446
Views
20
CrossRef citations to date
0
Altmetric
Review

Proteomics and liver fibrosis: identifying markers of fibrogenesis

, , &
Pages 421-431 | Published online: 09 Jan 2014

References

  • Friedman SL. Liver fibrosis – from bench to bedside. J. Hepatol.38, S38–S53 (2003).
  • Schuppan D, Ruehl M, Somasundaram R, Hahn EH. Matrix as a modulator of hepatic fibrogenesis. Semin. Liver Dis.21, 351–372 (2001).
  • Wallace K, Burt AD, Wright MC. Liver fibrosis. Biochem. J.411(1), 1–18 (2008).
  • Svegliati-Baroni G, De Minicis S, Marzioni M. Hepatic fibrogenesis in response to chronic liver injury: novel insights on the role of cell-to-cell interaction and transition. Liver Int.28(8), 1052–1064 (2008).
  • Møller S, Henriksen JH. Cardiovascular complications of cirrhosis. Gut57(2), 268–278 (2008).
  • Henderson NC, Forbes SJ. Hepatic fibrogenesis: from within and outwith. Toxicology254(3), 130–135 (2008).
  • Iredale J. Defining therapeutic targets for liver fibrosis: exploiting the biology of inflammation and repair. Pharmacol. Res.58(2), 129–136 (2008).
  • Friedman SL. Hepatic fibrosis – overview. Toxicology254(3), 120–129 (2008).
  • Friedman SL. Mechanisms of hepatic fibrogenesis. Gastroenterology134(6), 1655–1669 (2008).
  • Friedman SL, Bansal MB. Reversal of hepatic fibrosis – fact or fantasy? Hepatology43(2 Suppl. 1), S82–S88 (2006).
  • Iimuro Y, Brenner DA. Matrix metalloproteinase gene delivery for liver fibrosis. Pharm. Res.25(2), 249–258 (2008).
  • Guo J, Friedman SL. Hepatic fibrogenesis. Semin. Liver Dis.27(4), 413–426 (2007).
  • Bataller R, Brenner DA. Liver fibrosis. J. Clin. Invest.115(2), 209–218 (2005).
  • Ghiassi-Nejad Z, Friedman SL. Advances in antifibrotic therapy. Expert Rev. Gastroenterol. Hepatol.2(6), 803–816 (2008).
  • Rockey DC. Antifibrotic therapy in chronic liver disease. Clin. Gastroenterol. Hepatol.3(2), 95–107 (2005).
  • Said A, Lucey MR. Liver transplantation: an update 2008. Curr. Opin. Gastroenterol.24(3), 339–345 (2008).
  • Renz JF, Kin C, Kinkhabwala M et al. Utilization of extended donor criteria liver allografts maximizes donor use and patient access to liver transplantation. Ann. Surg.242(4), 556–563 (2005).
  • Brown RS, Rush SH, Rosen HR et al. Liver and intestine transplantation. Am. J. Transplant.4(Suppl. 9), 81–92 (2004).
  • Zachary D. Goodman. Grading and staging systems for inflammation and fibrosis in chronic liver diseases. J. Hepatol.47(4), 598–607 (2007).
  • Leroy V. Other non-invasive markers of liver fibrosis. Gastroenterol. Clin. Biol.32(6 Suppl 1), 52–57 (2008).
  • Murtagh J, Foerster V. Transient elastography (FibroScan) for non-invasive assessment of liver fibrosis. Issues Emerg. Health Technol.90, 1–4 (2006).
  • Gressner AM, Gao CF, Gressner OA. Non-invasive biomarkers for monitoring the fibrogenic process in liver: a short survey. World J. Gastroenterol.15(20), 2433–2440 (2009).
  • Sawyers CL. The cancer biomarker problem. Nature452(7187), 548–552 (2008).
  • van’t Veer LJ, Bernards R. Enabling personalized cancer medicine through analysis of gene-expression patterns. Nature452(7187), 564–570 (2008).
  • Neusser MA, Lindenmeyer MT, Kretzler M, Cohen CD. Genomic analysis in nephrology – towards systems biology and systematic medicine? Nephrol. Ther.4(5), 306–311 (2008).
  • Kurian S, Grigoryev Y, Head S, Campbell D, Mondala T, Salomon DR. Applying genomics to organ transplantation medicine in both discovery and validation of biomarkers. Int. Immunopharmacol.7(14), 1948–1960 (2007).
  • Walters KA, Katze MG. Using high-throughput genomics to study hepatitis C: what determines the outcome of infection? Antiviral Res.81(3), 198–208 (2009).
  • Day CP. Genes or environment to determine alcoholic liver disease and non-alcoholic fatty liver disease. Liver Int.26(9), 1021–1028 (2006).
  • Mas VR, Fisher RA, Archer KJ et al. Genes associated with progression and recurrence of hepatocellular carcinoma in hepatitis C patients waiting and undergoing liver transplantation: preliminary results. Transplantation83(7), 973–981 (2007).
  • Mas VR, Maluf DG, Archer KJ et al. Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma. Mol. Med.15(3–4), 85–94 (2009).
  • Lederer SL, Walters KA, Proll S et al. Distinct cellular responses differentiating alcohol- and hepatitis C virus-induced liver cirrhosis. Virol. J.3, 98–108 (2006).
  • Siu L, Foont J, Wands JR. Hepatitis C virus and alcohol. Semin. Liver Dis.29(2), 188–199 (2009).
  • Bhattacharya R, Shuhart MC. Hepatitis C and alcohol: interactions, outcomes, and implications. J. Clin. Gastroenterol.36(3), 242–252 (2003).
  • Szabo G, Aloman C, Polyak SJ, Weinman SA, Wands J, Zakhari S. Hepatitis C infection and alcohol use: a dangerous mix for the liver and antiviral immunity. Alcohol Clin. Exp. Res.30(4), 709–719 (2006).
  • Iizuka N, Oka M, Yamada-Okabe H et al. Differential gene expression in distinct virologic types of hepatocellular carcinoma: association with liver cirrhosis. Oncogene22(19), 3007–3014 (2003).
  • Song EJ, Babar SM, Oh E, Hasan MN, Hong HM, Yoo YS. CE at the omics level: towards systems biology--an update. Electrophoresis29(1), 129–142 (2008).
  • Diamond DL, Jacobs JM, Paeper B et al. Proteomic profiling of human liver biopsies: hepatitis C virus-induced fibrosis and mitochondrial dysfunction. Hepatology46(3), 649–657 (2007).
  • Mölleken C, Sitek B, Henkel C et al. Detection of novel biomarkers of liver cirrhosis by proteomic analysis. Hepatology49(4), 1257–1266 (2009).
  • Gorg A, Weiss W, Dunn MJ. Current two-dimensional electrophoresis technology for proteomics. Proteomics4(12), 3665–3685 (2004).
  • Wilkins MR, Appel RD, Van Eyk JE et al. Guidelines for the next 10 years of proteomics. Proteomics6(1), 4–8 (2006).
  • Tonge R, Shaw J, Middleton B et al. Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology. Proteomics1(3), 377–396 (2001).
  • Unlu M, Morgan ME, Minden JS. Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis18(11), 2071–2077 (1997).
  • Domon B, Aebersold R. Mass spectrometry and protein analysis. Science312(5771), 212–217 (2006).
  • Mann M, Hendrickson RC, Pandey A. Analysis of proteins and proteomes by mass spectrometry. Annu. Rev. Biochem.18, 2071–2077 (2001).
  • Veenstra TD. Global and targeted quantitative proteomics for biomarker discovery. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.847(1), 3–11 (2007).
  • Hu L, Ye M, Jiang X, Feng S, Zou H. Advances in hyphenated analytical techniques for shotgun proteome and peptidome analysis--a review. Anal. Chim. Acta598(2), 193–204 (2007).
  • Issaq HJ, Conrads TP, Prieto DA, Tirumalai R, Veenstra TD. SELDI-TOF MS for diagnostic proteomics. Anal. Chem.75(7), 148A–155A (2003).
  • Joos T, Bachmann J. Protein microarrays: potentials and limitations. Front. Biosci.4, 4376–4385 (2009).
  • Kopf E, Zharhary D. Antibody arrays – an emerging tool in cancer proteomics. 39(7–8), 1305–1317 (2007).
  • Cheung KJ, Tilleman K, Deforce D, Colle, Van Vlierberghe H. Proteomics in liver fibrosis is more than meets the eye. Eur. J. Gastroenterol. Hepatol.20(5), 450–464 (2008).
  • Jacobs JM, Diamond DL, Chan EY et al. Proteome analysis of liver cells expressing full-length hepatitis C virus replicon and biopsy specimens of posttransplantation liver from HCV-infected patients. J. Virol.79(12), 7556–7569 (2005).
  • Low TY, Leow CK, Salto-Tellez M, Chung MC. A proteomic analysis of thioacetamide-induced hepatotoxicity and cirrhosis in rat livers. Proteomics4(12), 3960–3974 (2004).
  • Kristensen DB, Kawada N, Imamura K et al. Proteome analysis of rat hepatic stellate cells. Hepatology32(2), 268–277 (2000).
  • Rockey DC, Bissell DM. Noninvasive measures of liver fibrosis. Hepatology43(2 Suppl. 1), S113–S120 (2006).
  • Thuluvath PJ, Krok KL. Noninvasive markers of fibrosis for longitudinal assessment of fibrosis in chronic liver disease: are they ready for prime time? Am. J. Gastroenterol.100(9), 1981–1983 (2005).
  • Sandrin L, Fourquet B, Hasquenoph JM et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasound Med. Biol.29(12), 1705–1713 (2003).
  • Castera L, Vergniol J, Foucher J et al. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology128(2), 343–350 (2005).
  • Ziol M, Handra-Luca A, Kettaneh A et al. Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C. Hepatology41, 48–54 (2005).
  • White IR, Patel K, Symonds WT et al. Serum proteomic analysis focused on fibrosis in patients with hepatitis C virus infection. J. Transl. Med.5, 33 (2007).
  • Poynard T, Morra R, Ingiliz P et al. Biomarkers of liver fibrosis. Adv. Clin. Chem.46, 131–160 (2008).
  • Ngo Y, Munteanu M, Messous D et al. A prospective analysis of the prognostic value of biomarkers (FibroTest) in patients with chronic hepatitis C. Clin. Chem.52(10), 1887–1896 (2006).
  • Poon TC, Hui AY, Chan HL et al. Prediction of liver fibrosis and cirrhosis in chronic hepatitis B infection by serum proteomic fingerprinting: a pilot study.Clin. Chem.51(2), 328–335 (2005).
  • Sun S, Lee NP, Poon RT et al. Oncoproteomics of hepatocellular carcinoma: from cancer markers’ discovery to functional pathways. Liver Int.27(8), 1021–1038 (2007).
  • Santamaría E, Muñoz J, Fernández-Irigoyen J, Prìeto J, Corrales FJ. Toward the discovery of new biomarkers of hepatocellular carcinoma by proteomics. Liver Int.27(20), 163–173 (2007).
  • Sun W, Zhong F, Zhi L, Zhou G, He F. Systematic -omics analysis of HBV-associated liver diseases.Cancer Lett. DOI:10.1016/j.canlet.2008.12.002 (2009) (Epub ahead of print).
  • Ward DG, Cheng Y, N’Kontchou G et al. Changes in the serum proteome associated with the development of hepatocellular carcinoma in hepatitis C-related cirrhosis. Br. J. Cancer94(2), 287–292 (2006).
  • Ward DG, Cheng Y, N’Kontchou G et al. Preclinical and post-treatment changes in the HCC-associated serum proteome. Br. J. Cancer95(10), 1379–1383 (2006).
  • Mas VR, Maluf DG, Archer KJ, Yanek K, Bornstein K, Fisher RA. Proteomic analysis of HCV cirrhosis and HCV-induced HCC: identifying biomarkers for monitoring HCV-cirrhotic patients awaiting liver transplantation. Transplantation87(1), 143–152 (2009).
  • American Liver Tumor Study Group. A randomized prospective multi-institutional trial of orthotopic liver transplantation or partial hepatic resection with or without adjuvant chemotherapy for hepatocellular carcinoma. Investigators Booklet and protocol 1998. United Network for Organ Sharing. Policy 3.6.4.4.1998.
  • Cui J, Kang X, Dai Z et al. Prediction of chronic hepatitis B, liver cirrhosis and hepatocellular carcinoma by SELDI-based serum decision tree classification. J. Cancer Res. Clin. Oncol.133(11), 825–834 (2007).
  • He QY, Zhu R, Lei T et al. Toward the proteomic identification of biomarkers for the prediction of HBV related hepatocellular carcinoma. J. Cell. Biochem.103(3), 740–752 (2008).
  • Wallace JC, Korth MJ, Diamond DL, Proll SC, Katze MG. Virology in the 21st century: finding function with functional genomics. Future Virol.1, 47–53 (2006).
  • Thorgeirsson SS, Lee JS, Grisham JW. Functional genomics of hepatocellular carcinoma. Hepatology43(Suppl.), S145–S150 (2006).
  • Issa R, Zhou X, Constandinou CM et al. Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology126, 1795–1808 (2004).
  • Asselah T, Bièche I, Paradis V, Bedossa P, Vidaud M, Marcellin P. Genetics, genomics, and proteomics: implications for the diagnosis and the treatment of chronic hepatitis C. Semin. Liver Dis.27(1), 13–27 (2007).
  • Gressner AM, Yagmur E, Lahme B, Gressner O, Stanzel S. Connective tissue growth factor in serum as a new candidate test for assessment of hepatic fibrosis. Clin Chem.52, 1815–1817 (2006).
  • Quan TE, Cowper S, Wu SP, Bockenstedt LK, Bucala R. Circulating fibrocytes: collagen-secreting cells of the peripheral blood. Int. J. Biochem. Cell. Biol.36, 598–606 (2004).
  • Kubota A, Okamura S, Omori F et al. High serum levels of granulocyte-macrophage colony-stimulating factor in patients with liver cirrhosis and granulocytopenia. Clin. Lab. Haematol.17, 61–63 (1995).
  • Tacke F, Gäbele E, Bataille F et al. Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells. Dig. Dis. Sci.52, 3404–3415 (2007).
  • Kuhn J, Prante C, Schön S, Götting C, Kleesiek K. Measurement of fibrosis marker xylosyltransferase I activity by HPLC electrospray ionization tandem mass spectrometry. Clin Chem.52, 2243–2249 (2006).

Websites

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.