Protein microarrays and novel detection platforms

References

• Hu Y, Huang X, Chen GY, Yao SQ. Recent advances in gel-based proteome profiling techniques. Mol. Biotechnol.28(1), 63–76 (2004).
   PubMed Web of Science ®Google Scholar
• Labaer J, Ramachandran N. Protein microarrays as tools for functional proteomics. Curr. Opin. Chem. Biol.9(1), 14–19 (2005).
   PubMed Web of Science ®Google Scholar
• Templin MF, Stoll D, Schwenk JM, Potz O, Kramer S, Joos TO. Protein microarrays: promising tools for proteomic research. Proteomics3(11), 2155–2166 (2003).
   PubMed Web of Science ®Google Scholar
• Chandra H, Srivastava S. Cell-free synthesis-based protein microarrays and their applications. Proteomics10(4), 717–730 (2010).
   PubMed Web of Science ®Google Scholar
• Espina V, Woodhouse EC, Wulfkuhle J, Asmussen HD, Petricoin EF III, Liotta LA. Protein microarray detection strategies: focus on direct detection technologies. J. Immunol. Methods290(1–2), 121–133 (2004).
   PubMed Web of Science ®Google Scholar
• Angenendt P. Progress in protein and antibody microarray technology. Drug Discov. Today10(7), 503–511 (2005).
   PubMed Web of Science ®Google Scholar
• Ray S, Chandra H, Srivastava S. Nanotechniques in proteomics: current status, promises and challenges. Biosens. Bioelectron.25(11), 2389–2401 (2010).
   PubMed Web of Science ®Google Scholar
• Yan J, Estévez MC, Smith JE et al. Dye-doped nanoparticles for bioanalysis. Nano Today2(3), 44–50 (2007).
   Web of Science ®Google Scholar
• Ray S, Mehta G, Srivastava S. Label-free detection techniques for protein microarrays: prospects, merits and challenges. Proteomics10(4), 731–748 (2010).
   PubMed Web of Science ®Google Scholar
• Wolf-Yadlin A, Sevecka M, MacBeath G. Dissecting protein function and signaling using protein microarrays. Curr. Opin. Chem. Biol.13(4), 398–405 (2009).
   PubMed Web of Science ®Google Scholar
• Hall DA, Ptacek J, Snyder M. Protein microarray technology. Mech. Ageing Dev.128(1), 161–167 (2007).
   PubMed Web of Science ®Google Scholar
• Walter JG, Kokpinar O, Friehs K, Stahl F, Scheper T. Systematic investigation of optimal aptamer immobilization for protein-microarray applications. Anal. Chem.80(19), 7372–7378 (2008).
   PubMed Web of Science ®Google Scholar
• Renberg B, Nordin J, Merca A et al. Affibody molecules in protein capture microarrays: evaluation of multidomain ligands and different detection formats. J. Proteome Res.6(1), 171–179 (2007).
   PubMed Web of Science ®Google Scholar
• Sanchez-Carbayo M. Antibody arrays: technical considerations and clinical applications in cancer. Clin. Chem.52(9), 1651–1659 (2006).
   PubMed Web of Science ®Google Scholar
• Shafer MW, Mangold L, Partin AW, Haab BB. Antibody array profiling reveals serum TSP-1 as a marker to distinguish benign from malignant prostatic disease. Prostate67(3), 255–267 (2007).
   PubMed Web of Science ®Google Scholar
• Robinson WH, DiGennaro C, Hueber W et al. Autoantigen microarrays for multiplex characterization of autoantibody responses. Nat. Med.8(3), 295–301 (2002).
   PubMed Web of Science ®Google Scholar
• Chen S, Zheng T, Shortreed MR, Alexander C, Smith LM. Analysis of cell surface carbohydrate expression patterns in normal and tumorigenic human breast cell lines using lectin arrays. Anal. Chem.79(15), 5698–5702 (2007).
   PubMedGoogle Scholar
• Chan SM, Ermann J, Su L, Fathman CG, Utz PJ. Protein microarrays for multiplex analysis of signal transduction pathways. Nat. Med.10(12), 1390–1396 (2004).
   PubMed Web of Science ®Google Scholar
• Ehrlich JR, Qin S, Liu BC. The ‘reverse capture’ autoantibody microarray: a native antigen-based platform for autoantibody profiling. Nat. Protoc.1(1), 452–460 (2006).
   PubMed Web of Science ®Google Scholar
• Sheehan KM, Calvert VS, Kay EW et al. Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma. Mol. Cell Proteomics4(4), 346–355 (2005).
   PubMed Web of Science ®Google Scholar
• Grubb RL, Calvert VS, Wulkuhle JD et al. Signal pathway profiling of prostate cancer using reverse phase protein arrays. Proteomics3(11), 2142–2146 (2003).
   PubMed Web of Science ®Google Scholar
• Akkiprik M, Nicorici D, Cogdell D et al. Dissection of signaling pathways in fourteen breast cancer cell lines using reverse-phase protein lysate microarray. Technol. Cancer Res. Treat.5(6), 543–551 (2006).
   PubMed Web of Science ®Google Scholar
• Espina V, Liotta LA, Petricoin EF III. Reverse-phase protein microarrays for theranostics and patient tailored therapy. Methods Mol. Biol.520, 89–105 (2009).
   PubMedGoogle Scholar
• Bertone P, Snyder M. Advances in functional protein microarray technology. FEBS J.272(21), 5400–5411 (2005).
   PubMed Web of Science ®Google Scholar
• Issaq HJ, Chan KC, Janini GM, Conrads TP, Veenstra TD. Multidimensional separation of peptides for effective proteomic analysis. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.817(1), 35–47 (2005).
   PubMed Web of Science ®Google Scholar
• He M, Taussig MJ. Single step generation of protein arrays from DNA by cell-free expression and in situ immobilisation (PISA method). Nucleic Acids Res.29(15), E73–E73 (2001).
   PubMed Web of Science ®Google Scholar
• Schwenk JM, Gry M, Rimini R, Uhlén M, Nilsson P. Antibody suspension bead arrays within serum proteomics. J. Proteome Res.7(8), 3168–3179 (2008).
   PubMed Web of Science ®Google Scholar
• Wong J, Sibani S, Lokko NN, LaBaer J, Anderson KS. Rapid detection of antibodies in sera using multiplexed self-assembling bead arrays. J. Immunol. Methods350(1–2), 171–182 (2009).
   PubMed Web of Science ®Google Scholar
• Elshal MF, McCoy JP. Multiplex bead array assays: performance evaluation and comparison of sensitivity to ELISA. Methods38(4), 317–323 (2006).
   PubMed Web of Science ®Google Scholar
• Nolan JP, Sklar LA. Suspension array technology: evolution of the flat-array paradigm. Trends Biotechnol.20(1), 9–12 (2002).
   PubMed Web of Science ®Google Scholar
• Ramachandran N, Raphael JV, Hainsworth E et al. Next-generation high-density self-assembling functional protein arrays. Nat. Methods5(6), 535–538 (2008).
   PubMed Web of Science ®Google Scholar
• Beare PA, Chen C, Bouman T et al. Candidate antigens for Q fever serodiagnosis revealed by immunoscreening of a Coxiella burnetii protein microarray. Clin. Vaccine Immunol.15(12), 1771–1779 (2008).
   PubMedGoogle Scholar
• Lopez JE, Beare PA, Heinzen RA et al. High-throughput identification of T-lymphocyte antigens from Anaplasma marginale expressed using in vitro transcription and translation. J. Immunol. Methods332(1–2), 129–141 (2008).
   PubMedGoogle Scholar
• Hurst R, Hook B, Slater MR, Hartnett J, Storts DR, Nath N. Protein–protein interaction studies on protein arrays: effect of detection strategies on signal-to-background ratios. Anal. Biochem.392(1), 45–53 (2009).
   PubMedGoogle Scholar
• Mei Q, Fredrickson CK, Jin S, Fan ZH. Toxin detection by a miniaturized in vitro protein expression array. Anal. Chem.77(17), 5494–5500 (2005).
   PubMed Web of Science ®Google Scholar
• Meng L, Michaud GA, Merkel JS et al. Protein kinase substrate identification on functional protein arrays. BMC Biotechnol.8, 22 (2008).
   PubMedGoogle Scholar
• Ptacek J, Devgan G, Michaud G et al. Global analysis of protein phosphorylation in yeast. Nature438(7068), 679–684 (2005).
   PubMed Web of Science ®Google Scholar
• Chen Z, Tabakman SM, Goodwin AP et al. Protein microarrays with carbon nanotubes as multicolor Raman labels. Nat. Biotechnol.26(11), 1285–1292 (2008).
   PubMed Web of Science ®Google Scholar
• Nam JM, Thaxton CS, Mirkin CA. Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins. Science301(5641), 1884–1886 (2003).
   PubMed Web of Science ®Google Scholar
• Thaxton CS, Elghanian R, Thomas AD et al. Nanoparticle-based bio-barcode assay redefines ‘undetectable’ PSA and biochemical recurrence after radical prostatectomy. Proc. Natl Acad. Sci. USA106(44), 18437–18442 (2009).
   PubMed Web of Science ®Google Scholar
• Edwards BS, Oprea T, Prossnitz ER, Sklar LA. Flow cytometry for high-throughput, high-content screening. Curr. Opin. Chem. Biol.8(4), 392–398 (2004).
   PubMed Web of Science ®Google Scholar
• Gantelius J, Hartmann M, Schwenk JM, Roeraade J, Andersson-Svahn H, Joos TO. Magnetic bead-based detection of autoimmune responses using protein microarrays. Nat. Biotechnol.26(6), 269–276 (2009).
   Google Scholar
• Morozov VN, Morozova TY. Active bead-linked immunoassay on protein microarrays. Anal. Chim. Acta564(1), 40–52 (2006).
   PubMedGoogle Scholar
• Miller JC, Zhou H, Kwekel J et al. Antibody microarray profiling of human prostate cancer sera: antibody screening and identification of potential biomarkers. Proteomics3(1), 56–63 (2003).
   PubMed Web of Science ®Google Scholar
• Haab BB. Methods and applications of antibody microarrays in cancer research. Proteomics3(11), 2116–2122 (2003).
   PubMed Web of Science ®Google Scholar
• Srivastava M, Eidelman O, Jozwik C et al. Serum proteomic signature for cystic fibrosis using an antibody microarray platform. Mol. Genet. Metab.87(4), 303–310 (2006).
   PubMed Web of Science ®Google Scholar
• Sreekumar A, Nyati MK, Varambally S et al. Profiling of cancer cells using protein microarrays: discovery of novel radiation-regulated proteins. Cancer Res.61(20), 7585–7593 (2001).
   PubMed Web of Science ®Google Scholar
• Lin Y, Huang R, Santanam N, Liu YG, Parthasarathy S, Huang RP. Profiling of human cytokines in healthy individuals with vitamin E supplementation by antibody array. Cancer Lett.187(1–2), 17–24 (2002).
   PubMed Web of Science ®Google Scholar
• Nielsen UB, Cardone MH, Sinskey AJ, MacBeath G, Sorger PK. Profiling receptor tyrosine kinase activation by using Ab microarrays. Proc. Natl Acad. Sci. USA100(16), 9330–9335 (2003).
   PubMed Web of Science ®Google Scholar
• Schweitzer B, Kingsmore SF. Measuring proteins on microarrays. Curr. Opin. Biotechnol.13(1), 14–19 (2002).
   PubMed Web of Science ®Google Scholar
• Shao W, Zhou Z, Laroche I et al. Optimization of rolling-circle amplified protein microarrays for multiplexed protein profiling. J. Biomed. Biotechnol.2003(5), 299–307 (2003).
   PubMedGoogle Scholar
• Zhou H, Bouwman K, Schotanus M et al. Two-color, rolling-circle amplification on antibody microarrays for sensitive, multiplexed serum-protein measurements. Genome Biol.5(4), R28 (2004).
   PubMed Web of Science ®Google Scholar
• Han XX, Zhao B, Ozaki Y. Surface-enhanced Raman scattering for protein detection. Anal. Bioanal. Chem.394(7), 1719–1727 (2009).
   PubMed Web of Science ®Google Scholar
• Li T, Guo L, Wang Z. Microarray based Raman spectroscopic detection with gold nanoparticle probes. Biosens. Bioelectron.23(7), 1125–1130 (2008).
   PubMedGoogle Scholar
• Cao YC, Jin R, Nam JM, Thaxton CS, Mirkin CA. Raman dye-labeled nanoparticle probes for proteins. J. Am. Chem. Soc.125(48), 14676–14677 (2003).
   PubMed Web of Science ®Google Scholar
• Kim D, Daniel WL, Mirkin CA. Microarray-based multiplexed scanometric immunoassay for protein cancer markers using gold nanoparticle probes. Anal. Chem.81(21), 9183–9187 (2009).
   PubMedGoogle Scholar
• Liang RQ, Tan CY, Ruan KC. Colorimetric detection of protein microarrays based on nanogold probe coupled with silver enhancement. J. Immunol. Methods285(2), 157–163 (2004).
   PubMed Web of Science ®Google Scholar
• Gao J, Liu D, Wang Z. Microarray-based study of carbohydrate-protein binding by gold nanoparticle probes. Anal. Chem.80(22), 8822–8827 (2008).
   PubMedGoogle Scholar
• Gao J, Liu C, Liu D, Wang Z, Dong S. Antibody microarray-based strategies for detection of bacteria by lectin-conjugated gold nanoparticle probes. Talanta81(4–5), 1816–1820 (2010).
   PubMedGoogle Scholar
• Resch-Genger U, Grabolle M, Cavaliere-Jaricot S, Nitschke R, Nann T. Quantum dots versus organic dyes as fluorescent labels. Nat. Methods5(9), 763–775 (2008).
   PubMed Web of Science ®Google Scholar
• Sun YP, Zhou B, Lin Y et al. Quantum-sized carbon dots for bright and colorful photoluminescence. J. Am. Chem. Soc.128(24), 7756–7757 (2006).
   PubMed Web of Science ®Google Scholar
• Jokerst JV, Raamanathan A, Christodoulides N et al. Nano-bio-chips for high performance multiplexed protein detection: determinations of cancer biomarkers in serum and saliva using quantum dot bioconjugate labels. Biosens. Bioelectron.24(12), 3622–3629 (2009).
   PubMed Web of Science ®Google Scholar
• Hu M, Yan J, He Y et al. Ultrasensitive, multiplexed detection of cancer biomarkers directly in serum by using a quantum dot-based microfluidic protein chip. ACS Nano.4(1), 488–494 (2010).
   PubMed Web of Science ®Google Scholar
• Zajac A, Song D, Qian W, Zhukov T. Protein microarrays and quantum dot probes for early cancer detection. Colloids Surf. B Biointerfaces58(2), 309–314 (2007).
   PubMed Web of Science ®Google Scholar
• Ghazani AA, Lee JA, Klostranec J et al. High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals. Nano Lett.6(12), 2881–2886 (2006).
   PubMed Web of Science ®Google Scholar
• Geho D, Lahar N, Gurnani P et al. Pegylated, steptavidin-conjugated quantum dots are effective detection elements for reverse-phase protein microarrays. Bioconjug. Chem.16(3), 559–566 (2005).
   PubMed Web of Science ®Google Scholar
• Drbohlavova J, Adam V, Kizek R, Hubalek J. Quantum dots-characterization, preparation and usage in biological systems. Int. J. Mol. Sci.10(2), 656–673 (2009).
   PubMed Web of Science ®Google Scholar
• Wu H, Huo Q, Varnum S et al. Dye-doped silica nanoparticle labels/protein microarray for detection of protein biomarkers. Analyst133(11), 1550–1555 (2008).
   PubMed Web of Science ®Google Scholar
• Wang L, Yang C, Tan W. Dual-luminophore-doped silica nanoparticles for multiplexed signaling. Nano Lett.5(1), 37–43 (2005).
   PubMed Web of Science ®Google Scholar
• Santra S, Zhang P, Wang K, Tapec R, Tan W. Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers. Anal. Chem.73(20), 4988–4993 (2001).
   PubMed Web of Science ®Google Scholar
• Deng T, Li JS, Jiang JH, Shen GL, Yu RQ. Preparation of near-IR fluorescent nanoparticles for fluorescence-anisotropy-based immunoagglutination assay in whole blood. Adv. Funct. Mater.16(16), 2147–2155 (2006).
   Web of Science ®Google Scholar
• Goluch ED, Nam JM, Georganopoulou DG et al. A bio-barcode assay for on-chip attomolar-sensitivity protein detection. Lab. Chip.6(10), 1293–1299 (2006).
   PubMed Web of Science ®Google Scholar
• Oh BK, Nam JM, Lee SW, Mirkin CA. A fluorophore-based bio-barcode amplification assay for proteins. Small2(1), 103–108 (2006).
   PubMedGoogle Scholar
• Stoeva SI, Lee JS, Smith JE, Rosen ST, Mirkin CA. Multiplexed detection of protein cancer markers with biobarcoded nanoparticle probes. J. Am. Chem. Soc.128(26), 8378–8379 (2006).
   PubMed Web of Science ®Google Scholar
• Faucher S, Martel A, Sherring A et al. Protein bead array for the detection of HIV-1 antibodies from fresh plasma and dried-blood-spot specimens. Clin. Chem.50(7), 1250–1253 (2004).
   PubMedGoogle Scholar
• Morgan E, Varro R, Sepulveda H et al. Cytometric bead array: a multiplexed assay platform with applications in various areas of biology. Clin. Immunol.110(3), 252–266 (2004).
   PubMed Web of Science ®Google Scholar
• Sklar LA, Carter MB, Edwards BS. Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening. Curr. Opin. Pharmacol.7(5), 527–534 (2007).
   PubMed Web of Science ®Google Scholar
• Schwenk JM, Lindberg J, Sundberg M, Uhlen M, Nilsson P. Determination of binding specificities in highly multiplexed bead-based assays for antibody proteomics. Mol. Cell Proteomics6(1), 125–132 (2007).
   PubMedGoogle Scholar
• Leblanc N, Gantelius J, Schwenk JM et al. Development of a magnetic bead microarray for simultaneous and simple detection of four pestiviruses. J. Virol. Methods155(1), 1–9 (2009).
   PubMedGoogle Scholar
• Stahl PL, Gantelius J, Natanaelsson C, Ahmadian A, Andersson-Svahn H, Lundeberg J. Visual DNA – identification of DNA sequence variations by bead trapping. Genomics90(6), 741–745 (2007).
   PubMedGoogle Scholar
• Ramachandran N, Larson DN, Stark PR, Hainsworth E, Labaer J. Emerging tools for real-time label-free detection of interactions on functional protein microarrays. FEBS J.272(21), 5412–5425 (2005).
   PubMed Web of Science ®Google Scholar
• Blow N. Proteins and proteomics: life on the surface. Nat. Methods6, 389–393 (2009).
   Web of Science ®Google Scholar
• Zhu SL, Zhang JB, Lin Yue LY, Hartono D, Liu AQ. Label-free protein detection via gold nanoparticles and localized surface plasmon resonance. Adv. Mat. Res.74, 95–98 (2009).
   Google Scholar
• D’Urso OS, De Blasi MD, Manera MG, Latronico MF, Rella R, Poltronieri P. Listeria monocytogenes detection with surface plasmon resonance and protein arrays. IEEE Sens. J.458–461 (2008).
   Google Scholar
• Wassaf D, Kuang G, Kopacz K et al. High-throughput affinity ranking of antibodies using surface plasmon resonance microarrays. Anal. Biochem.351(2), 241–253 (2006).
   PubMed Web of Science ®Google Scholar
• Klenkar G, Liedberg B. A microarray chip for label-free detection of narcotics. Anal. Bioanal. Chem.391(5), 1679–1688 (2008).
   PubMedGoogle Scholar
• Ladd J, Taylor AD, Piliarik M, Homola J, Jiang S. Label-free detection of cancer biomarker candidates using surface plasmon resonance imaging. Anal. Bioanal. Chem.393(4), 1157–1163 (2009).
   PubMed Web of Science ®Google Scholar
• Lausted C, Hu Z, Hood L. Quantitative serum proteomics from surface plasmon resonance imaging. Mol. Cell Proteomics7(12), 2464–2474 (2008).
   PubMed Web of Science ®Google Scholar
• Inoue Y, Mori T, Yamanouchi G et al. Surface plasmon resonance imaging measurements of caspase reactions on peptide microarrays. Anal. Biochem.375(1), 147–149 (2008).
   PubMedGoogle Scholar
• Ouellet E, Lausted C, Lin T, Yang CW, Hood L, Lagally ET. Parallel microfluidic surface plasmon resonance imaging arrays. Lab. Chip.10(5), 581–588 (2010).
   PubMedGoogle Scholar
• Srivastava S, Labaer J. Nanotubes light up protein arrays. Nat. Biotechnol.26(11), 1244–1246 (2008).
   PubMed Web of Science ®Google Scholar
• Okuno J, Maehashi K, Kerman K, Takamura Y, Matsumoto K, Tamiya E. Label-free immunosensor for prostate-specific antigen based on single-walled carbon nanotube array-modified microelectrodes. Biosens. Bioelectron.22(9–10), 2377–2381 (2007).
   PubMed Web of Science ®Google Scholar
• Joshi A, Punyani S, Bale SS, Yang H, Borca-Tasciuc T, Kane RS. Nanotube-assisted protein deactivation. Nat. Nanotechnol.3(1), 41–45 (2008).
   PubMedGoogle Scholar
• Welsher K, Liu Z, Sherlock SP et al. A route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice. Nat. Nanotechnol.4(11), 773–780 (2009).
   PubMed Web of Science ®Google Scholar
• Cid CC, Riu J, Maroto A, Rius FX. Carbon nanotube field effect transistors for the fast and selective detection of human immunoglobulin G. Analyst133(8), 1005–1008 (2008).
   PubMedGoogle Scholar
• Villamizar RA, Maroto A, Rius FX, Inza I, Figueras MJ. Fast detection of Salmonella infantis with carbon nanotube field effect transistors. Biosens. Bioelectron.24(2), 279–283 (2008).
   PubMed Web of Science ®Google Scholar
• Zheng G, Patolsky F, Cui Y, Wang WU, Lieber CM. Multiplexed electrical detection of cancer markers with nanowire sensor arrays. Nat. Biotechnol.23(10), 1294–1301 (2005).
   PubMed Web of Science ®Google Scholar
• Wang WU, Chen C, Lin KH, Fang Y, Lieber CM. Label-free detection of small-molecule-protein interactions by using nanowire nanosensors. Proc. Natl Acad. Sci. USA102(9), 3208–3212 (2005).
   PubMed Web of Science ®Google Scholar
• Patolsky F, Zheng G, Hayden O, Lakadamyali M, Zhuang X, Lieber CM. Electrical detection of single viruses. Proc. Natl Acad. Sci. USA101(39), 14017–14022 (2004).
   PubMed Web of Science ®Google Scholar
• Brammer KS, Choi C, Oh S et al. Antibiofouling, sustained antibiotic release by Si nanowire templates. Nano Lett.9(10), 3570–3574 (2009).
   PubMed Web of Science ®Google Scholar
• Hwang KS, Lee S, Kim SK, Lee JH, Kim TS. Micro- and nanocantilever devices and systems for biomolecule detection. Annu. Rev. Anal. Chem.2, 77–98 (2009).
   PubMedGoogle Scholar
• Braun T, Ghatkesar MK, Backmann N et al. Quantitative time-resolved measurement of membrane protein–ligand interactions using microcantilever array sensors. Nat. Nanotechnol.4(3), 179–185 (2009).
   PubMed Web of Science ®Google Scholar
• Sarphie D. Nanomechanical cantilever biosensors: a springboard to novel antibiotics. Innovations in Pharmaceutical Technology29, 12–17 (2009)
   Google Scholar
• Wee KW, Kang GY, Park J et al. Novel electrical detection of label-free disease marker proteins using piezoresistive self-sensing micro-cantilevers. Biosens. Bioelectron.20(10), 1932–1938 (2005).
   PubMed Web of Science ®Google Scholar
• Yue M, Stachowiak JC, Lin H, Datar R, Cote R, Majumdar A. Label-free protein recognition two-dimensional array using nanomechanical sensors. Nano Lett.8(2), 520–524 (2008).
   PubMed Web of Science ®Google Scholar
• Braun T, Backmann N, Vogtli M et al. Conformational change of bacteriorhodopsin quantitatively monitored by microcantilever sensors. Biophys. J.90(8), 2970–2977 (2006).
   PubMed Web of Science ®Google Scholar
• Huber F, Lang HP, Hegner M, Despont M, Drechsler U, Gerber C. Analyzing refractive index changes and differential bending in microcantilever arrays. Rev. Sci. Instrum.79(8), 086110 (2008).
   PubMedGoogle Scholar
• Dauksaite V, Lorentzen M, Besenbacher F, Kjems J. Antibody-based protein detection using piezoresistive cantilever arrays. Nanotechnology18(18), 125503 (2007).
   Web of Science ®Google Scholar
• Zhang H, Wu G, Tu H, Huang F. Discovery of serum biomarkers in astrocytoma by SELDI-TOF MS and proteinchip technology. J. Neurooncol.84(3), 315–323 (2007).
   PubMedGoogle Scholar
• Zhu XD, Zhang WH, Li CL, Xu Y, Liang WJ, Tien P. New serum biomarkers for detection of HBV-induced liver cirrhosis using SELDI protein chip technology. World J. Gastroenterol.10(16), 2327–2329 (2004).
   PubMed Web of Science ®Google Scholar
• Grus FH, Podust VN, Bruns K et al. SELDI-TOF-MS ProteinChip array profiling of tears from patients with dry eye. Invest. Ophthalmol. Vis. Sci.46(3), 863–876 (2005).
   PubMed Web of Science ®Google Scholar
• Cui JF, Liu YK, Zhou HJ et al. Screening serum hepatocellular carcinoma-associated proteins by SELDI-based protein spectrum analysis. World J. Gastroenterol.14(8), 1257–1262 (2008).
   PubMed Web of Science ®Google Scholar
• Mannello F, Medda V, Tonti GA. Protein profile analysis of the breast microenvironment to differentiate healthy women from breast cancer patients. Expert Rev. Proteomics6(1), 43–60 (2009).
   PubMed Web of Science ®Google Scholar
• Liu Y, Wang H, Huang J, Yang J, Liu B, Yang P. Microchip-based ELISA strategy for the detection of low-level disease biomarker in serum. Anal. Chim. Acta650(1), 77–82 (2009).
   PubMedGoogle Scholar
• Breitenstein M, Holzel R, Bier FF. Immobilization of different biomolecules by atomic force microscopy. J. Nanobiotechnology.8, 10 (2010).
   PubMedGoogle Scholar
• Soultani-Vigneron S, Dugas V, Rouillat MH et al. Immobilisation of oligo-peptidic probes for microarray implementation: characterisation by FTIR, atomic force microscopy and 2D fluorescence. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.822(1–2), 304–310 (2005).
   PubMed Web of Science ®Google Scholar
• Lynch M, Mosher C, Huff J, Nettikadan S, Johnson J, Henderson E. Functional protein nanoarrays for biomarker profiling. Proteomics4(6), 1695–1702 (2004).
   PubMed Web of Science ®Google Scholar
• Lee M, Kang DK, Yang HK et al. Protein nanoarray on Prolinker surface constructed by atomic force microscopy dip-pen nanolithography for analysis of protein interaction. Proteomics6(4), 1094–1103 (2006).
   PubMed Web of Science ®Google Scholar
• Lian W, Litherland SA, Badrane H et al. Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles. Anal. Biochem.334(1), 135–144 (2004).
   PubMed Web of Science ®Google Scholar
• Lee W, Lee JH, Oh BK, Choi JW. Detection of human serum albumin on protein array using scanning tunneling microscopy. Ultramicroscopy110(6), 723–728 (2010).
   PubMedGoogle Scholar
• Kanga D, Janga Y, Leea J, Kimb S, Oha B, Choi J. Electrical detection of prostate specific antigen on protein array using scanning tunneling microscopy. Curr. Appl. Phys.9(2), e33–e37 (2009).
   Google Scholar
• Yang L, Li Y, Erf GF. Interdigitated array microelectrode-based electrochemical impedance immunosensor for detection of Escherichia coli O157:H7. Anal. Chem.76(4), 1107–1113 (2004).
   PubMed Web of Science ®Google Scholar
• Xu H, Mao X, Zeng Q, Wang S, Kawde AN, Liu G. Aptamer-functionalized gold nanoparticles as probes in a dry-reagent strip biosensor for protein analysis. Anal. Chem.81(2), 669–675 (2009).
   PubMed Web of Science ®Google Scholar
• Komarova E, Reber K, Aldissi M, Bogomolova A. New multispecific array as a tool for electrochemical impedance spectroscopy-based biosensing. Biosens. Bioelectron.25(6), 1389–1394 (2010).
   PubMedGoogle Scholar
• Nedelkov D, Nelson RW. Practical considerations in BIA/MS: optimizing the biosensor-mass spectrometry interface. J. Mol. Recognit.13(3), 140–145 (2000).
   PubMed Web of Science ®Google Scholar
• Ozkumur E, Needham JW, Bergstein DA et al. Label-free and dynamic detection of biomolecular interactions for high-throughput microarray applications. Proc. Natl Acad. Sci. USA105(23), 7988–7992 (2008).
   PubMedGoogle Scholar
• Joo C, Ozkumur E, Unlu MS, Boer JF. Spectral-domain optical coherence phase microscopy for label-free multiplexed protein microarray assay. Biosens. Bioelectron.25(2), 275–281 (2009).
   PubMedGoogle Scholar
• Zhu H, Bilgin M, Bangham R et al. Global analysis of protein activities using proteome chips. Science293(5537), 2101–2105 (2001).
   PubMed Web of Science ®Google Scholar
• Arenkov P, Kukhtin A, Gemmell A, Voloshchuk S, Chupeeva V, Mirzabekov A. Protein microchips: use for immunoassay and enzymatic reactions. Anal. Biochem.278(2), 123–131 (2000).
   PubMed Web of Science ®Google Scholar
• Heijmans-Antonissen C, Wesseldijk F, Munnikes RJ et al. Multiplex bead array assay for detection of 25 soluble cytokines in blister fluid of patients with complex regional pain syndrome type 1. Mediators Inflamm.2006(1), 28398 (2006).
   PubMed Web of Science ®Google Scholar
• Khan SS, Smith MS, Reda D, Suffredini AF, McCoy JP Jr. Multiplex bead array assays for detection of soluble cytokines: comparisons of sensitivity and quantitative values among kits from multiple manufacturers. Cytometry B. Clin. Cytom.61(1), 35–39 (2004).
   PubMed Web of Science ®Google Scholar
• Konry T, Hayman RB, Walt DR. Microsphere-based rolling circle amplification microarray for the detection of DNA and proteins in a single assay. Anal. Chem.81(14), 5777–5782 (2009).
   PubMed Web of Science ®Google Scholar
• Hiep HM, Endo Y, Kerman K et al. A localized surface plasmon resonance based immunosensor for the detection of casein in milk. Sci. Technol. Adv. Mater.8, 331 (2007).
   Web of Science ®Google Scholar
• Wu G, Datar RH, Hansen KH, Thundat T, Cote RJ, Majumdar A. Bioassay of prostate-specific antigen (PSA) using microcantilevers. Nat. Biotechnol.19, 856–860 (2001).
   PubMed Web of Science ®Google Scholar
• Lee K, Kim E, Mirkin CA, Wolinsky SM. The use of nanoarrays for highly sensitive and selective detection of human immunodeficiency virus type 1 in plasma. Nano Lett.4 (10), 1869–1872 (2004).
   Web of Science ®Google Scholar
• Vorderwülbecke S, Cleverley S, Weinberger SR, Wiesner A. Protein quantification by the SELDI-TOF-MS-based ProteinChip® System. Nat. Methods2, 393–395 (2005).
   Google Scholar