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Editorial

Cellular stroke therapy: from cell replacement to trophic support

Pages 1187-1190 | Published online: 10 Jan 2014

References

  • Kelly SBT, Shah AK, Sun GH et al. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. Proc. Natl Acad. Sci. USA101(32), 11839–11844 (2004).
  • Guzman R, Uchida N, Bliss TM et al. Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc. Natl Acad. Sci. USA104(24), 10211–10216 (2007).
  • Cummings BJ, Uchida N, Tamaki SJ et al. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. Proc. Natl Acad. Sci. USA102(39), 14069–14074 (2005).
  • Krupinski J, Kumar P, Kumar S, Kaluza J. Increased expression of TGF-β 1 in brain tissue after ischemic stroke in humans. Stroke27(5), 852–857 (1996).
  • Krupinski J, Issa R, Bujny T et al. A putative role for platelet-derived growth factor in angiogenesis and neuroprotection after ischemic stroke in humans. Stroke28(3), 564–573 (1997).
  • Issa R, Krupinski J, Bujny T, Kumar S, Kaluza J, Kumar P. Vascular endothelial growth factor and its receptor, KDR, in human brain tissue after ischemic stroke. Lab. Invest.79(4), 417–425 (1999).
  • Issa R, AlQteishat A, Mitsios N et al. Expression of basic fibroblast growth factor mRNA and protein in the human brain following ischaemic stroke. Angiogenesis8(1), 53–62 (2005).
  • Cai W, Guzman R, Hsu AR et al. Positron emission tomography imaging of poststroke angiogenesis. Stroke40(1), 270–277 (2009).
  • Markus R, Reutens DC, Kazui S et al. Hypoxic tissue in ischaemic stroke: persistence and clinical consequences of spontaneous survival. Brain127(Pt 6), 1427–1436 (2004).
  • Guzman R, De Los Angeles A, Cheshier S et al. Intracarotid injection of fluorescence activated cell-sorted CD49d-positive neural stem cells improves targeted cell delivery and behavior after stroke in a mouse stroke model. Stroke39(4), 1300–1306 (2008).
  • Chen J, Zhang ZG, Li Y et al. Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats. Circ. Res.92(6), 692–699 (2003).
  • Park DH, Borlongan CV, Willing AE, Eve DJ, Sanberg PR. Human umbilical cord blood cell grafts for stroke. Cell. Transplant. pii: CT-2067 (2009) (Epub ahead of print).
  • Palmer TD, Willhoite AR, Gage FH. Vascular niche for adult hippocampal neurogenesis. J. Comp. Neurol.425(4), 479–494 (2000).
  • Roitbak T, Li L, Cunningham LA. Neural stem/progenitor cells promote endothelial cell morphogenesis and protect endothelial cells against ischemia via HIF-1α-regulated VEGF signaling. J. Cereb. Blood Flow Metab.28(9), 1530–1542 (2008).
  • Imitola J, Raddassi K, Park KI et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1α/CXC chemokine receptor 4 pathway. Proc. Natl Acad. Sci. USA101(52), 18117–18122 (2004).
  • Daadi M, Arac A, Davis A et al. Grafts of human embryonic stem cell-derived neural stem cells promote neuroanatomical rewiring and connectivity with host in hypoxia ischemia model of neonates. Stroke40(4), E105–E276 (2009).
  • Horie N, Andres RH, Keren-Gill H et al. Transplanted human neural progenitor cells enhance endogenous dendritic plasticity and axonal sprouting after stroke. Stroke40(4), E105–E276 (2009).
  • Liauw JA EC, Hoang S, Choi MP et al. Neural progenitor cells enhance synaptogenesis in neuronal cultures: a thrombospondin-dependent mechanism. In: Society for Neuroscience Annual Meeting Abstract. Society for Neuroscience, DC, USA (2006).
  • Jiang Q, Zhang ZG, Ding GL et al. MRI detects white matter reorganization after neural progenitor cell treatment of stroke. NeuroImage32(3), 1080–1089 (2006).
  • Arvidsson A CT, Kirik D, Kokaia Z, Lindvall O. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat. Med.8, 963–970 (2002).
  • Hoehn BD, Palmer TD, Steinberg GK. Neurogenesis in rats after focal cerebral ischemia is enhanced by indomethacin. Stroke36(12), 2718–2724 (2005).
  • Taguchi A, Soma T, Tanaka H et al. Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesis in a mouse model. J. Clin. Invest.114(3), 330–338 (2004).
  • Shen LH, Li Y, Chen J et al. Intracarotid transplantation of bone marrow stromal cells increases axon-myelin remodeling after stroke. Neuroscience137(2), 393–399 (2006).
  • Iordanova IK, Guzman R, Fuerer C, Nusse R, Steinberg GK. Canonical Wnt signaling promotes neurogenesis in the adult murine brain and reduces apoptotic cell death following focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism, XXIVth International Symposium on Cerebral Blood Flow and Metabolism: Brain and PET Meeting 2009. Chicago, IL, USA (2009).
  • Pluchino S, Zanotti L, Rossi B et al. Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism. Nature436(7048), 266–271 (2005).
  • Liesz A, Suri-Payer E, Veltkamp C et al. Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke. Nat. Med.15(2), 192–199 (2009).
  • Guzman R, Bliss T, De Los Angeles A, Moseley M, Palmer T, Steinberg G. Neural progenitor cells transplanted into the uninjured brain undergo targeted migration after stroke onset. J. Neurosci. Res.86(4), 873–882 (2008).
  • Modo M, Cash D, Mellodew K et al. Tracking transplanted stem cell migration using bifunctional, contrast agent-enhanced, magnetic resonance imaging. NeuroImage17(2), 803–811 (2002).
  • Hoehn M, Kustermann E, Blunk J et al. Monitoring of implanted stem cell migration in vivo: A highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. PNAS99(25), 16267–16272 (2002).
  • Nelson PT, Kondziolka D, Wechsler L et al. Clonal human (hNT) neuron grafts for stroke therapy: neuropathology in a patient 27 months after implantation. Am J Pathol160(4), 1201–1206 (2002).
  • Harting MT, Jimenez F, Xue H et al. Intravenous mesenchymal stem cell therapy for traumatic brain injury. J Neurosurg110(6), 1189–1197 (2009).
  • Fischer UM, Harting MT, Jimenez F et al. Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect. Stem Cells Dev.18(5), 683–692 (2009).
  • Borlongan CV, Hadman M, Sanberg CD, Sanberg PR. Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke. Stroke35(10), 2385–2389 (2004).
  • Andres RH CR, Lee SW, Gaeta X, Wang N, Gera A, Palmer TD, Steinberg GK, Guzman R. CCL2-induced chemotaxis is important for transendothelial targeted migration of neural stem cells in response to ischemic stroke. In: Society for Neuroscience Meeting. Neuroscience Meeting Planner, DC, USA 703–706 (2008).
  • Walczak P, Zhang J, Gilad AA et al. Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia. Stroke39(5), 1569–1574 (2008).
  • Yano S, Kuroda S, Shichinohe H, Hida K, Iwasaki Y. Do bone marrow stromal cells proliferate after transplantation into mice cerebral infarct? – a double labeling study. Brain research1065(1–2), 60–67 (2005).
  • Love JC, Wang JC, Dennis JC et al. Imaging of mesenchymal stem cell transplant by bioluminescence and PET. J. Nucl. Med.48(12), 2011–2020 (2007).
  • Li L, Jiang Q, Ding G et al. MRI identification of white matter reorganization enhanced by erythropoietin treatment in a rat model of focal ischemia. Stroke40(3), 936–941 (2009).
  • Saleh A, Schroeter M, Ringelstein A et al. Iron oxide particle-enhanced MRI suggests variability of brain inflammation at early stages after ischemic stroke. Stroke38(10), 2733–2737 (2007).
  • Aloya R, Shirvan A, Grimberg H et al. Molecular imaging of cell death in vivo by a novel small molecule probe. Apoptosis11(12), 2089–2101 (2006).
  • Savitz SI, Dinsmore J, Wu J, Henderson GV, Stieg P, Caplan LR. Neurotransplantation of fetal porcine cells in patients with basal ganglia infarcts: a preliminary safety and feasibility study. Cerebrovasc. Dis.20(2), 101–107 (2005).
  • Kondziolka D, Steinberg GK, Wechsler L et al. Neurotransplantation for patients with subcortical motor stroke: a phase 2 randomized trial. J. Neurosurg.103(1), 38–45 (2005).
  • Kondziolka D, Steinberg GK, Cullen SB, McGrogan M. Evaluation of surgical techniques for neuronal cell transplantation used in patients with stroke. Cell Transplant.13(7–8), 749–754 (2004).
  • Kondziolka D, Wechsler L, Goldstein S et al. Tranplantation of cultured human neuronal cells for patients with stroke. Neurology55, 565–569 (2000).
  • Stem Cell Therapies as an Emerging Paradigm in Stroke (STEPS): bridging basic and clinical science for cellular and neurogenic factor therapy in treating stroke. Stroke40(2), 510–515 (2009).

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