154
Views
12
CrossRef citations to date
0
Altmetric
Clinical Trial Report

TORAFIC study protocol: torasemide prolonged release versus furosemide in patients with chronic heart failure

, , , , , , & show all
Pages 897-904 | Published online: 10 Jan 2014

References

  • Mosterd A, Hoes AW, de Bruyne MC et al. Prevalence of heart failure and left ventricular dysfunction in the general population; The Rotterdam Study. Eur. Heart J.20, 447–455 (1999).
  • Anguita Sánchez M, Crespo Leiro MG, de Teresa Galván E et al; PRICE study investigators. Prevalence of heart failure in the Spanish general population aged over 45 years. Rev. Esp. Cardiol.61, 1041–1049 (2008).
  • McKee PA, Castelli WP, McNamara PM, Kannel WB. The natural history of congestive heart failure: the Framingham study. N. Engl. J. Med.285, 1441–1446 (1971).
  • Cleland JG, Gemmell I, Khand A, Boddy A. Is the prognosis of heart failure improving? Eur. Heart J.1, 229–241 (1999).
  • Cleland JG, Khand A, Clark A. The heart failure epidemic: exactly how big is it? Eur. Heart J.22, 623–626 (2001).
  • Mann DL, Bristow MR. Mechanisms and models in heart failure: the biomechanical model and beyond. Circulation111, 2837–2849 (2005).
  • Burlew BS, Weber KT. Connective tissue and the heart. Functional significance and regulatory mechanisms. Cardiol. Clin.18, 435–442 (2000).
  • Chapman RE, Spinale FG. Extracellular protease activation and unraveling of the myocardial interstitium: critical steps toward clinical applications. Am. J. Physiol. Heart Circ. Physiol.286, H1–H10 (2004).
  • Burlew BS, Weber KT. Cardiac fibrosis as a cause of diastolic dysfunction. Herz27, 92–98 (2002).
  • Brower GL, Gardner JD, Forman MF et al. The relationship between myocardial extracellular matrix remodeling and ventricular function. Eur. J. Cardiothorac. Surg.30, 604–610 (2006).
  • Díez J, González A, López B, Querejeta R. Mechanisms of disease: pathologic structural remodeling is more than adaptive hypertrophy in hypertensive heart disease. Nat. Clin. Pract. Cardiovasc. Med.2, 209–216 (2005).
  • Querejeta R, Varo N, López B et al. Serum carboxy-terminal propeptide procollagen type I is a marker of myocardial fibrosis in hypertensive heart disease. Circulation101, 1729–1735 (2000).
  • Querejeta R, López B, González A et al. Increased collagen type I synthesis in patients with heart failure of hypertensive origin: relation to myocardial fibrosis. Circulation110, 1263–1268 (2004).
  • López B, Querejeta R, Varo N et al. Usefulness of serum carboxy-terminal propeptide of procollagen type I in assessment of the cardioreparative ability of antihypertensive treatment in hypertensive patients. Circulation104, 286–291 (2001).
  • González A, López B, Ravassa S et al. Biochemical markers of myocardial remodelling in hypertensive heart disease. Cardiovasc. Res.81, 509–518 (2009).
  • Swedberg K, Cleland J, Dargie H et al; Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. Eur. Heart J.26, 1115–1140 (2005).
  • Hunt SA, Abraham WT, Chin MH et al; American College of Cardiology; American Heart Association Task Force on Practice Guidelines; American College of Chest Physicians; International Society for Heart and Lung Transplantation; Heart Rhythm Society: ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation112, E154–E235 (2005).
  • Ishido H, Senzaki H. Torasemide for the treatment of heart failure. Cardiovasc. Hematol. Disord. Drug Targets8, 127–132 (2008).
  • Cosín J, Díez J; TORIC investigators. Torasemide in chronic heart failure: results of the TORIC study. Eur. J. Heart Fail.4, 507–513 (2002).
  • Dunn CJ, Fitton A, Brogden RN. Torasemide. An update of its pharmacological properties and therapeutic efficacy. Drugs49, 121–142 (1995).
  • Knauf H, Mutschler E. Clinical pharmacokinetics and pharmacodynamics of torasemide. Clin. Pharmacokinet.34, 1–24 (1998).
  • Dodion L, Ambroes Y, Lameire N. A comparison of the pharmacokinetics and diuretic effects of two loop diuretics, torasemide and furosemide, in normal volunteers. Eur. J. Clin. Pharmacol.31, 21–27 (1986).
  • Vargo DL, Kramer WG, Black PK, Smith WB, Serpas T, Brater DC. Bioavailability, pharmacokinetics, and pharmacodynamics of torsemide and furosemide in patients with congestive heart failure. Clin. Pharmacol. Ther.57, 601–609 (1995).
  • Barbanoj MJ, Ballester MR, Antonijoan RM et al. A bioavailability/bioequivalence and pharmacokinetic study of two oral doses of torasemide (5 mg and 10 mg): prolonged-release versus the conventional formulation. Clin. Exp. Pharmacol. Physiol.36(5–6), 469–477 (2008).
  • Gropper S, Rojas MJ, Guglietta A et al. Single and repeated-dose, randomized, cross-over, bioavailability clinical trial of torasemide immediate release compared to a new prolonged release formulation of torasemide. Basic Clin. Pharmacol. Toxicol.99(Suppl. 1), 48 (2006) (Abstract).
  • Sutril Neo (torasemide prolonged release), summary of product characteristics. Ferrer Grupo, Barcelona, Spain (2006).
  • Roca-Cusachs A, Aracil-Vilar J, Calvo-Gómez C et al.; the Torasemide-PR in Hypertension Clinical Trial Investigators Group. Clinical effects of torasemide prolonged release in milt to moderate hypertension: a randomized non-inferiority trial versus torasemide immediate release. Cardiovasc. Ther.26, 91–100 (2008).
  • Veeraveedu PT, Watanabe K, Ma M et al. Comparative effects of torasemide and furosemide in rats with heart failure. Biochem. Pharmacol.75, 649–659 (2008).
  • Veeraveedu PT, Watanabe K, Ma M et al. Torasemide, a long-acting loop diuretic, reduces the progression of myocarditis to dilated cardiomyopathy. Eur. J. Pharmacol.581, 121–131 (2008).
  • López B, Querejeta R, González A, Sánchez E, Larman M, Díez J. Effects of loop diuretics on myocardial fibrosis and collagen type I turnover in chronic heart failure. J. Am. Coll. Cardiol.43, 2028–2035 (2004).
  • López B, González A, Beaumont J, Querejeta R, Larman M, Díez J. Identification of a potential antifibrotic mechanism of torasemide in patients with chronic heart failure. J. Am. Coll. Cardiol.50, 859–867 (2007).
  • López B, Querejeta R, González A, Beaumont J, Larman M, Díez J. Impact of treatment on myocardial lysyl oxidase expression and collagen cross-linking in patients with heart failure. Hypertension53(2), 236–242 (2009).
  • Rector TS, Cohn JN. Assessment of patient outcome with the Minnesota Living with Heart Failure Questionnaire: reliability and validity during a randomized, double-blind, placebo-controlled trial of pimobendan. Am. Heart J.124, 1017–1025 (1992).
  • Hansson L, Hedner T, Dahlöf B. Prospective randomized open blinded end-point (PROBE) study. A novel design for intervention trials. Prospective Randomized Open Blinded End-Point. Blood Press.1, 113–119 (1992).
  • Paulus WJ, Tschöpe C, Sanderson JE et al. How to diagnose diastolic heart failure: a consensus statement of the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. Eur. Heart J.28, 2539–2550 (2007).
  • European Society of Hypertension-European Society of Cardiology Guidelines Committee. 2003 European Society of Hypertension–European Society of Cardiology guidelines for the management of arterial hypertension. J. Hypertens.21, 1011–1053 (2003).
  • Karch FE, Lasagna L. Toward the operational identification of adverse drug reactions. Clin. Pharmacol. Ther.21, 247–254 (1977).
  • González A, López B, Díez J. New directions in the assessment and treatment of hypertensive heart disease. Curr. Opin. Nephrol. Hypertens.14, 428–434 (2005).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.