233
Views
43
CrossRef citations to date
0
Altmetric
Review

Activated platelets and atherosclerosis

, , , , , , & show all
Pages 1297-1307 | Published online: 10 Jan 2014

References

  • Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med.352, 1685–1695 (2005).
  • Nathan C, Ding A. Nonresolving inflammation. Cell140, 871–882 (2010).
  • von Hundelshausen P, Weber C. Platelets as immune cells: bridging inflammation and cardiovascular disease. Circ. Res.100, 27–40 (2007).
  • May AE, Seizer P, Gawaz M. Platelets: inflammatory firebugs of vascular walls. Arterioscler. Thromb. Vasc. Biol.28, 5–10 (2008).
  • Harrison P, Goodall AH. ‘Message in the platelet’ – more than just vestigial mRNA! Platelets19, 395–404 (2008).
  • Rendu F, Brohard-Bohn B. The platelet release reaction: granules’ constituents, secretion and functions. Platelets12, 261–273 (2001).
  • Smyth SS, McEver RP, Weyrich AS et al. Platelet functions beyond hemostasis. J. Thromb. Haemost.7, 1759–1766 (2009).
  • Furie B, Furie BC, Flaumenhaft R. A journey with platelet P-selectin: the molecular basis of granule secretion, signalling and cell adhesion. Thromb. Haemost.86, 214–221 (2001).
  • Kaneider NC, Kaser A, Tilg H, Ricevuti G, Wiedermann CJ. CD40 ligand-dependent maturation of human monocyte-derived dendritic cells by activated platelets. Int. J. Immunopathol. Pharmacol.16, 225–231 (2003).
  • Henn V, Slupsky JR, Gräfe M et al. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature391, 591–594 (1998).
  • Shattil SJ. Signaling through platelet integrin α IIb β 3: inside-out, outside-in, and sideways. Thromb. Haemost.82, 318–325 (1999).
  • Solum NO. Procoagulant expression in platelets and defects leading to clinical disorders. Arterioscler. Thromb. Vasc. Biol.19, 2841–2846 (1999).
  • Mann KG, Nesheim ME, Church WR, Haley P, Krishnaswamy S. Surface-dependent reactions of the vitamin K-dependent enzyme complexes. Blood76, 1–16 (1990).
  • Mosesson MW. Fibrinogen and fibrin structure and functions. J. Thromb. Haemost.3, 1894–1904 (2005).
  • Ogura H, Kawasaki T, Tanaka H et al. Activated platelets enhance microparticle formation and platelet-leukocyte interaction in severe trauma and sepsis. J. Trauma50, 801–809 (2001).
  • Nieuwland R, Berckmans RJ, Rotteveel-Eijkman RC et al. Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant. Circulation96, 3534–3541 (1997).
  • Tan KT, Lip GY. The potential role of platelet microparticles in atherosclerosis. Thromb. Haemost.94, 488–492 (2005).
  • Forlow SB, McEver RP, Nollert MU. Leukocyte-leukocyte interactions mediated by platelet microparticles under flow. Blood95, 1317–1323 (2000).
  • Boehlen F, Clemetson KJ. Platelet chemokines and their receptors: what is their relevance to platelet storage and transfusion practice? Transfus. Med.11, 403–417 (2001).
  • Kraaijeveld AO, de Jager SC, de Jager WJ et al. CC chemokine ligand-5 (CCL5/RANTES) and CC chemokine ligand-18 (CCL18/PARC) are specific markers of refractory unstable angina pectoris and are transiently raised during severe ischemic symptom. Circulation.116, 1931–1941 (2007).
  • Otterdal K, Smith C, Oie E et al. Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes. Blood108, 928–935 (2006).
  • Sandberg WJ, Otterdal K, Gullestad L et al. The tumor necrosis factor superfamily ligand APRIL (TNFSF13) is released upon platelet activation and expressed in atherosclerosis. Thromb. Haemost.102, 704–710 (2009).
  • Soslau G, Morgan DA, Jaffe JS, Brodsky I, Wang Y. Cytokine mRNA expression in human platelets and a megakaryocytic cell line and cytokine modulation of platelet function. Cytokine9, 405–411 (1997).
  • Weyrich AS, McIntyre TM, McEver RP, Prescott SM, Zimmerman GA. Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-α secretion. Signal integration and NF-κB translocation. J. Clin. Invest.95, 2297–2303 (1995).
  • Gawaz M, Brand K, Dickfeld T et al. Platelets induce alterations of chemotactic and adhesive properties of endothelial cells mediated through an interleukin-1-dependent mechanism. Implications for atherogenesis. Atherosclerosis148, 75–85 (2000).
  • Loppnow H, Bil R, Hirt S et al. Platelet-derived interleukin-1 induces cytokine production, but not proliferation of human vascular smooth muscle cells. Blood91, 134–141 (1998).
  • Damås JK, Jensenius M, Ueland T et al. Increased levels of soluble CD40L in African tick bite fever: possible involvement of TLRs in the pathogenic interaction between Rickettsia africae, endothelial cells, and platelets. J. Immunol.177, 2699–2706 (2006).
  • Clark SR, Ma AC, Tavener SA et al. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat. Med.13, 463–469 (2007).
  • Michelsen KS, Doherty TM, Shah PK, Arditi M. TLR signaling: an emerging bridge from innate immunity to atherogenesis. J. Immunol.173, 5901–5907 (2004).
  • Coppinger JA, Cagney G, Toomey S et al. Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood103, 2096–2104 (2004).
  • Breland UM, Michelsen AE, Skjelland M et al. Raised MCP-4 levels in symptomatic carotid atherosclerosis: an inflammatory link between platelet and monocyte activation. Cardiovasc. Res.86, 265–273 (2010).
  • Szabo MC, Butcher EC, McIntyre BW, Schall TJ, Bacon KB. RANTES stimulation ofT lymphocyte adhesion and activation: role for LFA-1 and ICAM-3. Eur. J. Immunol.27, 1061–1068 (1997).
  • von Hundelshausen P, Petersen F, Brandt E. Platelet-derived chemokines in vascular biology. Thromb. Haemost.97, 704–713 (2007).
  • von Hundelshausen P, Weber KS, Huo Y et al. RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium. Circulation103, 1772–1777 (2001).
  • Koenen RR, von Hundelshausen P, Nesmelova IV et al. Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice. Nat. Med.15, 97–103 (2009).
  • Massberg S, Konrad I, Schürzinger K et al. Platelet-derived stromal cell-derived factor-1 regulates adhesion and promotes differentiation of human CD34+ cells to endothelial progenitor cells. J. Exp. Med.203, 1221–1233 (2006).
  • Smith C, Damås JK, Otterdal K et al. Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation. J. Am. Coll. Cardiol.48, 1591–1599 (2006).
  • von Hundelshausen P, Koenen RR, Sack M et al. Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium. Blood105, 924–930 (2005).
  • Baltus T, von Hundelshausen P, Mause SF, Buhre W, Rossaint R, Weber C. Differential and additive effects of platelet-derived chemokines on monocyte arrest on inflamed endothelium under flow conditions. J. Leukoc. Biol.78, 435–441 (2005).
  • Fanslow WC, Srinivasan S, Paxton R, Gibson MG, Spriggs MK, Armitage RJ. Structural characteristics of CD40 ligand that determine biological function. Semin. Immunol.6, 267–278 (1994).
  • Zhang Y, Cao HJ, Graf B, Meekins H, Smith TJ, Phipps RP. CD40 engagement up-regulates cyclooxygenase-2 expression and prostaglandin E2 production in human lung fibroblasts. J. Immunol.160, 1053–1057 (1998).
  • Aukrust P, Müller F, Ueland T et al. Enhanced levels of soluble and membrane-bound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromes. Circulation100, 614–620 (1999).
  • Henn V, Steinbach S, Büchner K, Presek P, Kroczek RA. The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40. Blood98, 1047–1054 (2001).
  • Xu H, Zhang X, Mannon RB, Kirk AD. Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154. J. Clin. Invest.116, 769–774 (2006).
  • Ferroni P, Santilli F, Guadagni F, Basili S, Davì G. Contribution of platelet-derived CD40 ligand to inflammation, thrombosis and neoangiogenesis. Curr. Med. Chem.14, 2170–2180 (2007).
  • Poggi M, Jager J, Paulmyer-Lacroix O et al. The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes. Diabetologia52, 1152–1163 (2009).
  • Natal C, Restituto P, Iñigo C, Colina I, Díez J, Varo N. The proinflammatory mediator CD40 ligand is increased in the metabolic syndrome and modulated by adiponectin. J. Clin. Endocrinol. Metab.93, 2319–2327 (2008).
  • Deregibus MC, Buttiglieri S, Russo S, Bussolati B, Camussi G. CD40-dependent activation of phosphatidylinositol 3-kinase/Akt pathway mediates endothelial cell survival and in vitro angiogenesis. J. Biol. Chem.278, 18008–18014 (2003).
  • Longo CR, Arvelo MB, Patel VI et al. A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis. Circulation108, 1113–1118 (2003).
  • Urbich C, Dernbach E, Aicher A, Zeiher AM, Dimmeler S. CD40 ligand inhibits endothelial cell migration by increasing production of endothelial reactive oxygen species. Circulation106, 981–986 (2002).
  • Chai H, Yan S, Wang H et al. CD40 ligand increases expression of its receptor CD40 in human coronary artery endothelial cells. Surgery140, 236–242 (2006).
  • Zirlik A, Maier C, Gerdes N et al. CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1. Circulation115, 1571–1580 (2007).
  • Celik S, Langer H, Stellos K et al. Platelet-associated LIGHT (TNFSF14) mediates adhesion of platelets to human vascular endothelium. Thromb. Haemost.98, 798–805 (2007).
  • Chang YH, Hsieh SL, Chao Y, Chou YC, Lin WW. Proinflammatory effects of LIGHT through HVEM and LTbR interactions in cultured human umbilical vein endothelial cells. J. Biomed. Sci.12, 363–375 (2005).
  • Sandberg WJ, Halvorsen B, Yndestad A et al. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis. Circ. Res.104, 60–68 (2009).
  • Heo SK, Ju SA, Lee SC et al. LIGHT enhances the bactericidal activity of human monocytes and neutrophils via HVEM. J. Leukoc. Biol.79, 330–338 (2006).
  • Damås JK, Otterdal K, Yndestad A et al. Soluble CD40 ligand in pulmonary arterial hypertension: possible pathogenic role of the interaction between platelets and endothelial cells. Circulation110, 999–1005 (2004).
  • Ueland T, Otterdal K, Lekva T et al. Dickkopf-1 enhances inflammatory interaction between platelets and endothelial cells and shows increased expression in atherosclerosis. Arterioscler. Thromb. Vasc. Biol.29, 1228–1234 (2009).
  • Damås JK, Waehre T, Yndestad A et al. Interleukin-7-mediated inflammation in unstable angina: possible role of chemokines and platelets. Circulation107, 2670–2676 (2003).
  • Waehre T, Damås JK, Yndestad A et al. Effect of activated platelets on expression of cytokines in peripheral blood mononuclear cells – potential role of prostaglandin E2. Thromb. Haemost.92, 1358–1367 (2004).
  • King SM, McNamee RA, Houng AK, Patel R, Brands M, Reed GL. Platelet dense-granule secretion plays a critical role in thrombosis and subsequent vascular remodeling in atherosclerotic mice. Circulation120, 785–791 (2009).
  • Stenina OI, Plow EF. Counterbalancing forces: what is thrombospondin-1 doing in atherosclerotic lesions? Circ. Res.103, 1053–1055 (2008).
  • Kimura K, Hashiguchi T, Deguchi T et al. Serum VEGF – as a prognostic factor of atherosclerosis. Atherosclerosis194, 182–188 (2007).
  • Otterdal K, Andreassen AK, Yndestad A et al. Raised LIGHT levels in pulmonary arterial hypertension: potential role in thrombus formation. Am. J. Respir. Crit. Care Med.177, 202–207 (2008).
  • Massberg S, Brand K, Grüner S et al. A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation. J. Exp. Med.196, 887–896 (2002).
  • Huo Y, Schober A, Forlow SB et al. Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E. Nat. Med.9, 61–67 (2003).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.