1,019
Views
20
CrossRef citations to date
0
Altmetric
Editorial

Towards molecular diagnostics of invasive fungal infections

&
Pages 397-401 | Published online: 09 Jan 2014

References

  • Cornely OA. Aspergillus to Zygomycetes: causes, risk factors, prevention, and treatment of invasive fungal infections. Infection36(4), 296–313 (2008).
  • Donowitz GR, Maki DG, Crnich CJ, Pappas PG, Rolston KV. Infections in the neutropenic patient – new views of an old problem. Hematology Am. Soc. Hematol. Educ. Program113–139 (2001).
  • Nucci M, Spector N, Bueno AP et al. Risk factors and attributable mortality associated with superinfections in neutropenic patients with cancer. Clin. Infect. Dis.24(4), 575–579 (1997).
  • Walsh TJ, Anaissie EJ, Denning DW et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America. Clin. Infect. Dis.46(3), 327–360 (2008).
  • Richardson M, Lass-Florl C. Changing epidemiology of systemic fungal infections. Clin. Microbiol. Infect.14(Suppl. 4), 5–24 (2008).
  • Caston-Osorio JJ, Rivero A, Torre-Cisneros J. Epidemiology of invasive fungal infection. Int. J. Antimicrob. Agents32(Suppl. 2), S103–S109 (2008).
  • Lass-Florl C. The changing face of epidemiology of invasive fungal disease in Europe. Mycoses52(3), 197–205 (2009).
  • Marr KA, Patterson T, Denning D. Aspergillosis. Pathogenesis, clinical manifestations, and therapy. Infect. Dis. Clin. North Am.16(4), 875–894, vi (2002).
  • Kontoyiannis DP, Lionakis MS, Lewis RE et al. Zygomycosis in a tertiary-care cancer center in the era of Aspergillus-active antifungal therapy: a case–control observational study of 27 recent cases. J. Infect. Dis.191(8), 1350–1360 (2005).
  • Hope WW, Walsh TJ, Denning DW. Laboratory diagnosis of invasive aspergillosis. Lancet Infect. Dis.5(10), 609–622 (2005).
  • Pasqualotto AC, Denning DW. Diagnosis of invasive fungal infections – current limitations of classical and new diagnostic methods. Busin. Brief.: Eur. Oncol. Rev. 2005 (2005).
  • Ascioglu S, Rex JH, de Pauw B et al. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin. Infect. Dis.34(1), 7–14 (2002).
  • Ellepola AN, Morrison CJ. Laboratory diagnosis of invasive candidiasis. J. Microbiol (Seoul, Korea),43(Spec. No), 65–84 (2005).
  • Simoneau E, Kelly M, Labbe AC, Roy J, Laverdiere M. What is the clinical significance of positive blood cultures with Aspergillus sp in hematopoietic stem cell transplant recipients? A 23 year experience. Bone Marrow Transplant.35(3), 303–306 (2005).
  • Barnes RA. Early diagnosis of fungal infection in immunocompromised patients. J. Antimicrob. Chemother.61(Suppl. 1), i3–i6 (2008).
  • Leeflang MM, Debets-Ossenkopp YJ, Visser CE et al. Galactomannan detection for invasive aspergillosis in immunocompromized patients. Cochrane Database Syst. Rev.(4), CD007394 (2008).
  • Adam O, Auperin A, Wilquin F et al. Treatment with piperacillin-tazobactam and false-positive Aspergillus galactomannan antigen test results for patients with hematological malignancies. Clin. Infect. Dis.38(6), 917–920 (2004).
  • Zandijk E, Mewis A, Magerman K, Cartuyvels R. False-positive results by the platelia Aspergillus galactomannan antigen test for patients treated with amoxicillin-clavulanate. Clin. Vaccine Immunol.15(7), 1132–1133 (2008).
  • Racil Z, Kocmanova I, Lengerova M, Winterova J, Mayer J. Intravenous PLASMA-LYTE as a major cause of false-positive results of platelia Aspergillus test for galactomannan detection in serum. J. Clin. Microbiol.45(9), 3141–3142 (2007).
  • Wheat LJ, Walsh TJ. Diagnosis of invasive aspergillosis by galactomannan antigenemia detection using an enzyme immunoassay. Eur. J. Clin. Microbiol. Infect. Dis.27(4), 245–251 (2008).
  • Steinbach WJ, Addison RM, McLaughlin L et al. Prospective Aspergillus galactomannan antigen testing in pediatric hematopoietic stem cell transplant recipients. Pediatr. Infect. Dis. J.26(7), 558–564 (2007).
  • Marty FM, Koo S. Role of (1-->3)-β-D-glucan in the diagnosis of invasive aspergillosis. Med. Mycol.1–8 (2008).
  • Pickering JW, Sant HW, Bowles CA, Roberts WL, Woods GL. Evaluation of a (1-->3)-β-D-glucan assay for diagnosis of invasive fungal infections. J. Clin. Microbiol.43(12), 5957–5962 (2005).
  • Persat F, Ranque S, Derouin F et al. Contribution of the (1-->3)-β-D-glucan assay for diagnosis of invasive fungal infections. J. Clin. Microbiol.46(3), 1009–1013 (2008).
  • De Pauw B, Walsh TJ, Donnelly JP et al. Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. Clin. Infect. Dis.46(12), 1813–1821 (2008).
  • Raad I, Hanna H, Sumoza D, Albitar M. Polymerase chain reaction on blood for the diagnosis of invasive pulmonary aspergillosis in cancer patients. Cancer94(4), 1032–1036 (2002).
  • El-Mahallawy HA, Shaker HH, Ali Helmy H, Mostafa T, Razak Abo-Sedah A. Evaluation of pan-fungal PCR assay and Aspergillus antigen detection in the diagnosis of invasive fungal infections in high risk paediatric cancer patients. Med. Mycol.44(8), 733–739 (2006).
  • Lau A, Chen S, Sorrell T et al. Development and clinical application of a panfungal PCR assay to detect and identify fungal DNA in tissue specimens. J. Clin. Microbiol.45(2), 380–385 (2007).
  • Loffler J, Hebart H, Sepe S et al. Detection of PCR-amplified fungal DNA by using a PCR-ELISA system. Med. Mycol.36(5), 275–279 (1998).
  • Lass-Florl C, Gunsilius E, Gastl G et al. Diagnosing invasive aspergillosis during antifungal therapy by PCR analysis of blood samples. J. Clin. Microbiol.42(9), 4154–4157 (2004).
  • Florent M, Katsahian S, Vekhoff A et al. Prospective evaluation of a polymerase chain reaction-ELISA targeted to Aspergillus fumigatus and Aspergillus flavus for the early diagnosis of invasive aspergillosis in patients with hematological malignancies. J. Infect. Dis.193(5), 741–747 (2006).
  • Loeffler J, Henke N, Hebart H et al. Quantification of fungal DNA by using fluorescence resonance energy transfer and the light cycler system. J. Clin. Microbiol.38(2), 586–590 (2000).
  • White PL, Linton CJ, Perry MD, Johnson EM, Barnes RA. The evolution and evaluation of a whole blood polymerase chain reaction assay for the detection of invasive aspergillosis in hematology patients in a routine clinical setting. Clin. Infect. Dis.42(4), 479–486 (2006).
  • Baskova L, Landlinger C, Preuner S, Lion T. The Pan-AC assay: a single-reaction real-time PCR test for quantitative detection of a broad range of Aspergillus and Candida species. J. Med. Microbiol.56(Pt 9), 1167–1173 (2007).
  • Klingspor L, Jalal S. Molecular detection and identification of Candida and Aspergillus spp. from clinical samples using real-time PCR. Clin. Microbiol. Infect.12(8), 745–753 (2006).
  • Vollmer T, Stormer M, Kleesiek K, Dreier J. Evaluation of novel broad-range real-time PCR assay for rapid detection of human pathogenic fungi in various clinical specimens. J. Clin. Microbiol.46(6), 1919–1926 (2008).
  • Schabereiter-Gurtner C, Selitsch B, Rotter ML, Hirschl AM, Willinger B. Development of novel real-time PCR assays for detection and differentiation of eleven medically important Aspergillus and Candida species in clinical specimens. J. Clin. Microbiol.45(3), 906–914 (2007).
  • Skladny H, Buchheidt D, Baust C et al. Specific detection of Aspergillus species in blood and bronchoalveolar lavage samples of immunocompromised patients by two-step PCR. J. Clin. Microbiol.37(12), 3865–3871 (1999).
  • Williamson EC, Leeming JP, Palmer HM et al. Diagnosis of invasive aspergillosis in bone marrow transplant recipients by polymerase chain reaction. Br. J. Haematol.108(1), 132–139 (2000).
  • Halliday C, Hoile R, Sorrell T et al. Role of prospective screening of blood for invasive aspergillosis by polymerase chain reaction in febrile neutropenic recipients of haematopoietic stem cell transplants and patients with acute leukaemia. Br. J. Haematol.132(4), 478–486 (2006).
  • Leinberger DM, Schumacher U, Autenrieth IB, Bachmann TT. Development of a DNA microarray for detection and identification of fungal pathogens involved in invasive mycoses. J. Clin. Microbiol.43(10), 4943–4953 (2005).
  • Spiess B, Seifarth W, Hummel M et al. DNA microarray-based detection and identification of fungal pathogens in clinical samples from neutropenic patients. J. Clin. Microbiol.45(11), 3743–3753 (2007).
  • Loeffler J, Dorn C, Hebart H et al. Development and evaluation of the nuclisens basic kit NASBA for the detection of RNA from Candida species frequently resistant to antifungal drugs. Diagn. Microbiol. Infect. Dis.45(3), 217–220 (2003).
  • Landlinger C, Baskova L, Preuner S et al. Identification of fungal species by fragment length analysis of the internally transcribed spacer 2 region. Eur. J. Clin. Microbiol. Infect. Dis.28(6), 613–622 (2008).
  • Leaw SN, Chang HC, Sun HF et al. Identification of medically important yeast species by sequence analysis of the internal transcribed spacer regions. J. Clin. Microbiol.44(3), 693–699 (2006).
  • Diaz MR, Fell JW. High-throughput detection of pathogenic yeasts of the genus trichosporon. J. Clin. Microbiol.42(8), 3696–3706 (2004).
  • Das S, Brown TM, Kellar KL, Holloway BP, Morrison CJ. DNA probes for the rapid identification of medically important Candida species using a multianalyte profiling system. FEMS Immunol. Med. Microbiol.46(2), 244–250 (2006).
  • Landlinger C, Preuner S, Willinger B et al. Species-specific identification of a wide range of clinically relevant fungal pathogens by the Luminex xMAPTM technology. J. Clin. Microbiol. DOI: 10.1128/JCM.01558-08 (2009) (Epub ahead of print).
  • Gharizadeh B, Norberg E, Loffler J et al. Identification of medically important fungi by the pyrosequencing technology. Mycoses47(1–2), 29–33 (2004).
  • Montero CI, Shea YR, Jones PA et al. Evaluation of pyrosequencing technology for the identification of clinically relevant non-dematiaceous yeasts and related species. Eur. J. Clin. Microbiol. Infect. Dis.27(9), 821–830 (2008).
  • Landlinger C, Baskova L, Preuner S et al. Rapid detection of invasive fungal infections in hemato-oncological patients. Blood (ASH Annual Meeting Abstracts)112, 1468(2008).
  • Loeffler J, Hebart H, Brauchle U, Schumacher U, Einsele H. Comparison between plasma and whole blood specimens for detection of Aspergillus DNA by PCR. J. Clin. Microbiol.38(10), 3830–3833 (2000).
  • Metwally L, Fairley DJ, Coyle PV et al. Comparison of serum and whole-blood specimens for the detection of Candida DNA in critically ill, non-neutropenic patients. J. Med. Microbiol.57(Pt 10), 1269–1272 (2008).
  • Mengoli C, Cruciani M, Barnes RA, Loeffler J, Donnelly JP. Use of PCR for diagnosis of invasive aspergillosis: systematic review and meta-analysis. Lancet Infect. Dis.9(2), 89–96 (2009).
  • White PL, Barton R, Guiver M et al. A consensus on fungal polymerase chain reaction diagnosis?: a United Kingdom–Ireland evaluation of polymerase chain reaction methods for detection of systemic fungal infections. J. Mol. Diagn.8(3), 376–384 (2006).

Patent

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.