Advanced search
Publication Cover
Expert Review of Molecular Diagnostics Volume 12, 2012 - Issue 8
Submit an article Journal homepage
89
Views
1
CrossRef citations to date
0
Altmetric
Review

Actionable theranostics for global maternal health: a focus on HIV and malaria

Parvaz Madadi Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, ON, Canada. [email protected]; Motherisk Program, Hospital for Sick Children, Toronto, ON, Canada; Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, ON, Canada. [email protected]; Motherisk Program, Hospital for Sick Children, Toronto, ON, Canada
,
Ehijie FO Enato Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Benin, Benin City, Nigeria; Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
&
Asnat Walfisch High-Risk Pregnancy Unit, Hillel-Yaffe Medical Center, Hadera, Israel; High-Risk Pregnancy Unit, Hillel-Yaffe Medical Center, Hadera, Israel
Pages 831-840 | Published online: 09 Jan 2014

References

  • United Nations General Assembly. United Nations Millennium Declaration. A/RES/55/2. United Nations, New York, NY, USA (2000).
  • Lozano R, Wang H, Foreman KJ et al. Progress towards Millennium Development Goals 4 and 5 on maternal and child mortality: an updated systematic analysis. Lancet 378(9797), 1139–1165 (2011).
  • Hogan MC, Foreman KJ, Naghavi M et al. Maternal mortality for 181 countries, 1980-2008: a systematic analysis of progress towards Millennium Development Goal 5. Lancet 375(9726), 1609–1623 (2010).
  • Vitoria M, Granich R, Gilks CF et al. The global fight against HIV/AIDS, tuberculosis, and malaria: current status and future perspectives. Am. J. Clin. Pathol. 131(6), 844–848 (2009).
  • Ezechi O, Odberg Petterson K, Byamugisha J. HIV/AIDS, tuberculosis, and malaria in pregnancy. J. Pregnancy doi:10.1155/2012/140826 (2012) (Epub ahead of print).
  • Turnbull ER, Kancheya NG, Harris JB, Topp SM, Henostroza G, Reid SE. A model of tuberculosis screening for pregnant women in resource-limited settings using Xpert MTB/RIF. J. Pregnancy doi:10.1155/2012/565049 (2012) (Epub ahead of print).
  • Ozdemir V, Husereau D, Hyland S, Samper S, Salleh MZ. Personalized medicine beyond genomics: new technologies, global health diplomacy and anticipatory governance. Curr. Pharmacogenomics Person. Med. 7(4), 225–230 (2009).
  • Bruce-Chwatt LJ. Chemotherapy of Malaria (2nd Edition). World Health Organization, Geneva, Switzerland (1986).
  • World Health Organization Expert Committee on Malaria. WHO Technical Report Series 892, 12th Report: 3–6, Geneva, Switzerland (2000).
  • White NJ, Breman JG. Malaria and other diseases caused by red blood cells parasites. In: Harrison’s Principles of Internal Medicine (14th Edition). Fauci AS, Braunwald E, Isselbacher KJ et al. (Eds). McGraw-Hill, NY, USA, 1180–1189 (1998).
  • Brabin BJ. An analysis of malaria in pregnancy in Africa. Bull. World Health Organ. 61(6), 1005–1016 (1983).
  • Menéndez C, D’Alessandro U, ter Kuile FO. Reducing the burden of malaria in pregnancy by preventive strategies. Lancet Infect. Dis. 7(2), 126–135 (2007).
  • Menendez C. Malaria in pregnancy: a priority area of malaria research and control. Parasitol. Today 11(5), 178–183 (1995).
  • World Health Organization. A Strategic Framework for Malaria Prevention and Control During Pregnancy in the African Region. World Health Organization Regional Office for Africa, Brazzaville – AFR/MAL/04.01 (2004).
  • Rogerson SJ, Boeuf P. New approaches to pathogenesis of malaria in pregnancy. Parasitology 134(Pt 13), 1883–1893 (2007).
  • Desai M, ter Kuile FO, Nosten F et al. Epidemiology and burden of malaria in pregnancy. Lancet Infect. Dis. 7(2), 93–104 (2007).
  • Steketee RW, Nahlen BL, Parise ME, Menendez C. The burden of malaria in pregnancy in malaria-endemic areas. Am. J. Trop. Med. Hyg. 64(Suppl. 1–2), 28–35 (2001).
  • Hassan Sel-D, Haggaz AE, Mohammed-Elhassan EB, Malik EM, Adam I. Fluorescence microscope (Cyscope) for malaria diagnosis in pregnant women in Medani Hospital, Sudan. Diagn. Pathol. doi:10.1186/1746-1596-6-88 (2011) (Epub ahead of print).
  • Nankabirwa J, Zurovac D, Njogu JN et al. Malaria misdiagnosis in Uganda – implications for policy change. Malar. J. 8, 66 (2009).
  • Erdman LK, Kain KC. Molecular diagnostic and surveillance tools for global malaria control. Travel Med. Infect. Dis. 6(1–2), 82–99 (2008).
  • Mockenhaupt FP, Bedu-Addo G, von Gaertner C et al. Detection and clinical manifestation of placental malaria in southern Ghana. Malar. J. 5, 119 (2006).
  • Bulmer JN, Rasheed FN, Francis N, Morrison L, Greenwood BM. Placental malaria I. Pathological classification. Histopathology 22(3), 2110218 (1993).
  • Muehlenbachs A, Fried M, McGready R et al. A novel histological grading scheme for placental malaria applied in areas of high and low malaria transmission. J. Infect. Dis. 202(10), 1608–1616 (2010).
  • Mayor A, Moro L, Aguilar R et al. How hidden can malaria be in pregnant women? Diagnosis by microscopy, placental histology, polymerase chain reaction and detection of histidine-rich protein 2 in plasma. Clin. Infect. Dis. 54(11), 1561–1568 (2012).
  • Taylor BJ, Martin KA, Arango E, Agudelo OM, Maestre A, Yanow SK. Real-time PCR detection of Plasmodium directly from whole blood and filter paper samples. Malar. J. 10, 244 (2011).
  • Kaigala GV, Hoang VN, Stickel A et al. An inexpensive and portable microchip-based platform for integrated RT-PCR and capillary electrophoresis. Analyst 133(3), 331–338 (2008).
  • Manage DP, Lauzon J, Atrazhev A et al. A miniaturized and integrated gel post platform for multiparameter PCR detection of herpes simplex viruses from raw genital swabs. Lab Chip 12(9), 1664–1671 (2012).
  • Shulman CE, Marshall T, Dorman EK et al. Malaria in pregnancy: adverse effects on haemoglobin levels and birthweight in primigravidae and multigravidae. Trop. Med. Int. Health 6(10), 770–778 (2001).
  • ter Kuile FO, Terlouw DJ, Phillips-Howard PA et al. Reduction of malaria during pregnancy by permethrin-treated bed nets in an area of intense perennial malaria transmission in western Kenya. Am. J. Trop. Med. Hyg. 68(Suppl. 4), 50–60 (2003).
  • Enato EF, Mens PF, Okhamafe AO, Okpere EE, Pogoson E, Schallig HD. Plasmodium falciparum malaria in pregnancy: prevalence of peripheral parasitaemia, anaemia and malaria care-seeking behaviour among pregnant women attending two antenatal clinics in Edo State, Nigeria. J. Obstet. Gynaecol. 29(4), 301–306 (2009).
  • Enato EF, Okhamafe AO, Okpere EE. A survey of knowledge, attitude and practice of malaria management among pregnant women from two health care facilities in Nigeria. Acta Obstet. Gynecol. Scand. 86(1), 33–36 (2007).
  • Worrall E, Hill J, Webster J, Mortimer J. Experience of targeting subsidies on insecticide-treated nets: what do we know and what are the knowledge gaps? Trop. Med. Int. Health 10(1), 19–31 (2005).
  • Greenwood BM, Bojang K, Whitty CJ, Targett GA. Malaria. Lancet 365(9469), 1487–1498 (2005).
  • Welch K, Fuster M. Barriers in access to insecticide-treated bednets for malaria prevention: an analysis of Cambodian DHS data. J. Vector Borne Dis. 49(1), 1–7 (2012).
  • Hamel MJ, Otieno P, Bayoh N et al. The combination of indoor residual spraying and insecticide-treated nets provides added protection against malaria compared with insecticide-treated nets alone. Am. J. Trop. Med. Hyg. 85(6), 1080–1086 (2011).
  • Briand V, Cottrell G, Massougbodji A, Cot M. Intermittent preventive treatment for the prevention of malaria during pregnancy in high transmission areas. Malar. J. 6, 160 (2007).
  • Greenwood B. Review: intermittent preventive treatment – a new approach to the prevention of malaria in children in areas with seasonal malaria transmission. Trop. Med. Int. Health 11(7), 983–991 (2006).
  • Brentlinger PE, Dgedge M, Correia MA et al. Intermittent preventive treatment of malaria during pregnancy in central Mozambique. Bull. World Health Organ. 85(11), 873–879 (2007).
  • van Eijk AM, Ayisi JG, ter Kuile FO et al. Effectiveness of intermittent preventive treatment with sulphadoxine-pyrimethamine for control of malaria in pregnancy in western Kenya: a hospital-based study. Trop. Med. Int. Health 9(3), 351–360 (2004).
  • Vallely A, Vallely L, Changalucha J, Greenwood B, Chandramohan D. Intermittent preventive treatment for malaria in pregnancy in Africa: what’s new, what’s needed? Malar. J. 6, 16 (2007).
  • Amor A, Toro C, Fernández-Martínez A, Baquero M, Benito A, Berzosa P. Molecular markers in Plasmodium falciparum linked to resistance to anti-malarial drugs in samples imported from Africa over an eight-year period (2002–2010): impact of the introduction of artemisinin combination therapy. Malar. J. 11, 100 (2012).
  • McGready R, Cho T, Keo NK et al. Artemisinin antimalarials in pregnancy: a prospective treatment study of 539 episodes of multidrug-resistant Plasmodium falciparum. Clin. Infect. Dis. 33(12), 2009–2016 (2001).
  • Adam I, Ali DM, Abdalla MA. Artesunate plus sulfadoxine-pyrimethamine in the treatment of uncomplicated Plasmodium falciparum malaria during pregnancy in eastern Sudan. Trans. R. Soc. Trop. Med. Hyg. 100(7), 632–635 (2006).
  • Adam I, Elwasila E, Mohammed Ali DA, Elansari E, Elbashir MI. Artemether in the treatment of falciparum malaria during pregnancy in eastern Sudan. Trans. R. Soc. Trop. Med. Hyg. 98(9), 509–513 (2004).
  • Dellicour S, Hall S, Chandramohan D, Greenwood B. The safety of artemisinins during pregnancy: a pressing question. Malar. J. 6, 15 (2007).
  • Abdool-Karim Q, Abouzahr C, Dehne K et al. HIV and maternal mortality: turning the tide. Lancet 375(9730), 1948–1949 (2010).
  • McIntyre J. Mothers infected with HIV. Br. Med. Bull. 67, 127–135 (2003).
  • Corbett EL, Watt CJ, Walker N et al. The growing burden of tuberculosis: global trends and interactions with the HIV epidemic. Arch. Intern. Med. 163(9), 1009–1021 (2003).
  • Uneke CJ, Ogbonna A. Malaria and HIV co-infection in pregnancy in sub-Saharan Africa: impact of treatment using antimalarial and antiretroviral agents. Trans. R. Soc. Trop. Med. Hyg. 103(8), 761–767 (2009).
  • Mwapasa V, Rogerson SJ, Molyneux ME et al. The effect of Plasmodium falciparum malaria on peripheral and placental HIV-1 RNA concentrations in pregnant Malawian women. AIDS 18(7), 1051–1059 (2004).
  • McIntyre J. Maternal health and HIV. Reprod. Health Matters 13(25), 129–135 (2005).
  • Kwalombota M. The effect of pregnancy in HIV-infected women. AIDS Care 14(3), 431–433 (2002).
  • Watts DH. Management of human immunodeficiency virus infection in pregnancy. N. Engl. J. Med. 346(24), 1879–1891 (2002).
  • Kourtis AP, Bulterys M, Nesheim SR, Lee FK. Understanding the timing of HIV transmission from mother to infant. JAMA 285(6), 709–712 (2001).
  • Kourtis AP, Jamieson DJ, de Vincenzi I et al. Prevention of human immunodeficiency virus-1 transmission to the infant through breastfeeding: new developments. Am. J. Obstet. Gynecol. 197(Suppl. 3), S113–S122 (2007).
  • Kourtis AP, Lee FK, Abrams EJ, Jamieson DJ, Bulterys M. Mother-to-child transmission of HIV-1: timing and implications for prevention. Lancet Infect. Dis. 6(11), 726–732 (2006).
  • Ticconi C, Mapfumo M, Dorrucci M et al. Effect of maternal HIV and malaria infection on pregnancy and perinatal outcome in Zimbabwe. J. Acquir. Immune Defic. Syndr. 34(3), 289–294 (2003).
  • Mofenson LM, Laughon BE. Human immunodeficiency virus, mycobacterium tuberculosis, and pregnancy: a deadly combination. Clin. Infect. Dis. 45(2), 250–253 (2007).
  • Rogerson SJ, Hviid L, Duffy PE, Leke RF, Taylor DW. Malaria in pregnancy: pathogenesis and immunity. Lancet Infect. Dis. 7(2), 105–117 (2007).
  • Pillay T, Khan M, Moodley J et al. The increasing burden of tuberculosis in pregnant women, newborns and infants under 6 months of age in Durban, KwaZulu-Natal. S. Afr. Med. J. 91(11), 983–987 (2001).
  • Pai NP, Pai M. Point-of-care diagnostics for HIV and tuberculosis: landscape, pipeline, and unmet needs. Discov. Med. 13(68), 35–45 (2012).
  • Pai NP, Tulsky JP, Cohan D, Colford JM Jr, Reingold AL. Rapid point-of-care HIV testing in pregnant women: a systematic review and meta-analysis. Trop. Med. Int. Health 12(2), 162–173 (2007).
  • Pant Pai N, Joshi R, Dogra S et al. Evaluation of diagnostic accuracy, feasibility and client preference for rapid oral fluid-based diagnosis of HIV infection in rural India. PLoS ONE 2(4), e367 (2007).
  • Pant Pai N, Balram B, Shivkumar S et al. Head-to-head comparison of accuracy of a rapid point-of-care HIV test with oral versus whole-blood specimens: a systematic review and meta-analysis. Lancet Infect. Dis. 12(5), 373–380 (2012).
  • Chin CD, Laksanasopin T, Cheung YK et al. Microfluidics-based diagnostics of infectious diseases in the developing world. Nat. Med. 17(8), 1015–1019 (2011).
  • Creek T, Tanuri A, Smith M et al. Early diagnosis of human immunodeficiency virus in infants using polymerase chain reaction on dried blood spots in Botswana’s national program for prevention of mother-to-child transmission. Pediatr. Infect. Dis. J. 27(1), 22–26 (2008).
  • Sherman GG, Cooper PA, Coovadia AH et al. Polymerase chain reaction for diagnosis of human immunodeficiency virus infection in infancy in low resource settings. Pediatr. Infect. Dis. J. 24(11), 993–997 (2005).
  • Tuomala RE, Shapiro DE, Mofenson LM et al. Antiretroviral therapy during pregnancy and the risk of an adverse outcome. N. Engl. J. Med. 346(24), 1863–1870 (2002).
  • Lubomirov R, Colombo S, di Iulio J et al.; Swiss HIV Cohort Study. Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study. J. Infect. Dis. 203(2), 246–257 (2011).
  • McAlister C, Baskett TF. Female education and maternal mortality: a worldwide survey. J. Obstet. Gynaecol. Can. 28(11), 983–990 (2006).

Websites

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.