191
Views
10
CrossRef citations to date
0
Altmetric
Theme: Epilepsy - Review

Is it time to consider cognitive behavioral therapy for persons with epilepsy? Clues from pathophysiology, treatment and functional neuroimaging

, , &
Pages 1911-1927 | Published online: 09 Jan 2014

References

  • Goodwin RD, Devanand DP. Stroke, depression, and functional health outcomes among adults in the community. J. Geriatr. Psychiatry Neurol.21(1), 41–46 (2008).
  • Dobkin RD, Allen LA, Menza M. Cognitive–behavioral therapy for depression in Parkinson’s disease: a pilot study. Mov. Disord.22(7), 946–952 (2007).
  • Veazey C, Aki SO, Cook KF, Lai EC, Kunik ME. Prevalence and treatment of depression in Parkinson’s disease. J. Neuropsychiatry Clin. Neurosci.17(3), 310–323 (2005).
  • Kulaksizoglu IB. Mood and anxiety disorders in patients with myasthenia gravis: aetiology, diagnosis and treatment. CNS Drugs21(6), 473–481 (2007).
  • Reuber M, Burness C, Howlett S, Brazier J, Grunewald R. Tailored psychotherapy for patients with functional neurological symptoms: a pilot study. J. Psychosom. Res.63(6), 625–632 (2007).
  • Bowis J. ‘Out of the shadows’: the political view. Epilepsia43(Suppl. 6), 16–17 (2002).
  • Reynolds EH. The ILAE/IBE/WHO Global Campaign against Epilepsy: Bringing Epilepsy ‘Out of the Shadows’. Epilepsy Behav.1(4), S3–S8 (2000).
  • Moore JL, Elliott JO, Lu B, Klatte ET, Charyton C. Serious psychological distress among persons with epilepsy based on the 2005 California Health Interview Survey. Epilepsia50(5), 1077–1084 (2009).
  • Gilliam FG. Diagnosis and treatment of mood disorders in persons with epilepsy. Curr. Opin. Neurol.18(2), 129–133 (2005).
  • Hecimovic H, Goldstein JD, Sheline YI, Gilliam FG. Mechanisms of depression in epilepsy from a clinical perspective. Epilepsy Behav.4(Suppl. 3), S25–30 (2003).
  • Kanner AM. Epilepsy and mood disorders. Epilepsia48(Suppl. 9), 20–22 (2007).
  • Boylan LS, Flint LA, Labovitz DL, Jackson SC, Starner K, Devinsky O. Depression but not seizure frequency predicts quality of life in treatment-resistant epilepsy. Neurology62(2), 258–261 (2004).
  • Mendez MF, Cummings JL, Benson DF. Depression in epilepsy. Significance and phenomenology. Arch. Neurol.43(8), 766–770 (1986).
  • Comer RJ. Abnormal psychology. Worth Publishers, NY, USA (2007).
  • Harden CL, Goldstein MA. Mood disorders in patients with epilepsy: epidemiology and management. CNS Drugs16(5), 291–302 (2002).
  • Tellez-Zenteno JF, Patten SB, Jette N, Williams J, Wiebe S. Psychiatric comorbidity in epilepsy: a population-based analysis. Epilepsia48(12), 2336–2344 (2007).
  • Ettinger A, Reed M, Cramer J; Epilepsy Impact Project Group. Depression and comorbidity in community-based patients with epilepsy or asthma. Neurology63(6), 1008–1014 (2004).
  • Kanner AM. Depression and epilepsy: a review of multiple facets of their close relation. Neurol. Clin.27(4), 865–880 (2009).
  • Hesdorffer DC, Hauser WA, Olafsson E, Ludvigsson P, Kjartansson O. Depression and suicide attempt as risk factors for incident unprovoked seizures. Ann. Neurol.59(1), 35–41 (2006).
  • Blumer D, Montouris G, Davies K. The interictal dysphoric disorder: recognition, pathogenesis, and treatment of the major psychiatric disorder of epilepsy. Epilepsy Behav.5(6), 826–840 (2004).
  • Cramer JA, Blum D, Fanning K, Reed M; Epilepsy Impact Project Group. The impact of comorbid depression on health resource utilization in a community sample of people with epilepsy. Epilepsy Behav.5(3), 337–342 (2004).
  • Cramer JA, Blum D, Reed M, Fanning K; Epilepsy Impact Project Group. The influence of comorbid depression on seizure severity. Epilepsia44(12), 1578–1584 (2003).
  • Lee WC, Arcona S, Thomas SK, Wang Q, Hoffmann MS, Pashos CL. Effect of comorbidities on medical care use and cost among refractory patients with partial seizure disorder. Epilepsy Behav.7(1), 123–126 (2005).
  • Wiegartz P, Seidenberg M, Woodard A, Gidal B, Hermann B. Co-morbid psychiatric disorder in chronic epilepsy: recognition and etiology of depression. Neurology53(5 Suppl. 2), S3–S8 (1999).
  • Kanner AM, Kozak AM, Frey M. The use of sertraline in patients with epilepsy: is it safe? Epilepsy Behav.1(2), 100–105 (2000).
  • Suurmeijer TP, Reuvekamp MF, Aldenkamp BP. Social functioning, psychological functioning, and quality of life in epilepsy. Epilepsia42(9), 1160–1168 (2001).
  • Thapar A, Kerr M, Harold G. Stress, anxiety, depression, and epilepsy: investigating the relationship between psychological factors and seizures. Epilepsy Behav.14(1), 134–140 (2009).
  • Hesdorffer DC, Hauser WA, Annegers JF, Cascino G. Major depression is a risk factor for seizures in older adults. Ann. Neurol.47(2), 246–249 (2000).
  • Kanner AM. Depression and epilepsy: a new perspective on two closely related disorders. Epilepsy Curr.6(5), 141–146 (2006).
  • Kanner AM. Depression in epilepsy: a neurobiologic perspective. Epilepsy Curr.5(1), 21–27 (2005).
  • Albano C, Cupello A, Mainardi P, Scarrone S, Favale E. Successful treatment of epilepsy with serotonin reuptake inhibitors: proposed mechanism. Neurochem. Res.31(4), 509–514 (2006).
  • Theodore WH, Hasler G, Giovacchini G et al. Reduced hippocampal 5HT1A PET receptor binding and depression in temporal lobe epilepsy. Epilepsia48(8), 1526–1530 (2007).
  • Alper K, Schwartz KA, Kolts RL, Khan A. Seizure incidence in psychopharmacological clinical trials: an analysis of Food and Drug Administration (FDA) summary basis of approval reports. Biol. Psychiatry62(4), 345–354 (2007).
  • Kessing LV, Harhoff M, Andersen PK. Increased rate of treatment with antidepressants in patients with epilepsy. Epilepsy Behav.11(1), 39–45 (2007).
  • Fournier JC, DeRubeis RJ, Hollon SD et al. Antidepressant drug effects and depression severity: a patient-level meta-analysis. JAMA303(1), 47–53 (2010).
  • Bannan N. Multimodal therapy of treatment resistant depression: a study and analysis. Int. J. Psychiatry Med.35(1), 27–39 (2005).
  • Prinjha S, Chapple A, Herxheimer A, McPherson A. Many people with epilepsy want to know more: a qualitative study. Fam. Pract.22(4), 435–441 (2005).
  • DeRubeis RJ, Siegle GJ, Hollon SD. Cognitive therapy versus medication for depression: treatment outcomes and neural mechanisms. Nat. Rev. Neurosci.9(10), 788–796 (2008).
  • Hollon SD, Stewart MO, Strunk D. Enduring effects for cognitive behavior therapy in the treatment of depression and anxiety. Annu. Rev. Psychol.57(1), 285–315 (2006).
  • Nezu AM, Nezu CM, McMurran M. Problem-solving therapy. In: General Principles and Empirically Supported Techniques of Cognitive Behavior Therapy. O’Donohue WT, Fisher JE (Eds). John Wiley & Sons Inc., NJ, USA, 500–505 (2009).
  • Goldstein LH, McAlpine M, Deale A, Toone BK, Mellers JD. Cognitive behaviour therapy with adults with intractable epilepsy and psychiatric co-morbidity: preliminary observations on changes in psychological state and seizure frequency. Behav. Res. Ther.41(4), 447–460 (2003).
  • Au A, Chan F, Li K, Leung P, Li P, Chan J. Cognitive–behavioral group treatment program for adults with epilepsy in Hong Kong. Epilepsy Behav.4(4), 441–446 (2003).
  • Tan SY, Bruni J. Cognitive–behavior therapy with adult patients with epilepsy: a controlled outcome study. Epilepsia27(3), 225–233 (1986).
  • Davis GR, Armstrong HE Jr, Donovan DM, Temkin NR. Cognitive–behavioral treatment of depressed affect among epileptics: preliminary findings. J. Clin. Psychol.40(4), 930–935 (1984).
  • Spector S, Tranah A, Cull C, Goldstein LH. Reduction in seizure frequency following a short-term group intervention for adults with epilepsy. Seizure8(5), 297–303 (1999).
  • Roffman JL, Marci CD, Glick DM, Dougherty DD, Rauch SL. Neuroimaging and the functional neuroanatomy of psychotherapy. Psychol. Med.35(10), 1385–1398 (2005).
  • Merlet I, Ostrowsky K, Costes N et al. 5-HT1A receptor binding and intracerebral activity in temporal lobe epilepsy: an [18F]MPPF–PET study. Brain127(Pt 4), 900–913 (2004).
  • Toczek MT, Carson RE, Lang L et al. PET imaging of 5-HT1A receptor binding in patients with temporal lobe epilepsy. Neurology60(5), 749–756 (2003).
  • Merlet I, Ryvlin P, Costes N et al. Statistical parametric mapping of 5-HT1A receptor binding in temporal lobe epilepsy with hippocampal ictal onset on intracranial EEG. Neuroimage22(2), 886–896 (2004).
  • Didelot A, Ryvlin P, Lothe A, Merlet I, Hammers A, Mauguiere F. PET imaging of brain 5-HT1A receptors in the preoperative evaluation of temporal lobe epilepsy. Brain131(Pt 10), 2751–2764 (2008).
  • Theodore WH. Epilepsy and depression: imaging potential common factors. Clin. EEG Neurosci.35(1), 38–45 (2004).
  • Richardson EJ, Griffith HR, Martin RC et al. Structural and functional neuroimaging correlates of depression in temporal lobe epilepsy. Epilepsy Behav.10(2), 242–249 (2007).
  • Lothe A, Didelot A, Hammers A et al. Comorbidity between temporal lobe epilepsy and depression: a [18F]MPPF PET study. Brain131(Pt 10), 2765–2782 (2008).
  • Hasler G, Bonwetsch R, Giovacchini G et al. 5-HT1A receptor binding in temporal lobe epilepsy patients with and without major depression. Biol. Psychiatry.62(11), 1258–1264 (2007).
  • Bromfield EB, Altshuler L, Leiderman DB et al. Cerebral metabolism and depression in patients with complex partial seizures. Arch. Neurol.49(6), 617–623 (1992).
  • Victoroff JI, Benson F, Grafton ST, Engel J Jr, Mazziotta JC. Depression in complex partial seizures. Electroencephalography and cerebral metabolic correlates. Arch. Neurol.51(2), 155–163 (1994).
  • Savic I, Lindstrom P, Gulyas B, Halldin C, Andree B, Farde L. Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy. Neurology62(8), 1343–1351 (2004)
  • Giovacchini G, Toczek MT, Bonwetsch R et al. 5-HT1A receptors are reduced in temporal lobe epilepsy after partial-volume correction. J. Nucl. Med.46(7), 1128–1135 (2005).
  • Kennedy SH, Evans KR, Kruger S et al. Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression. Am. J. Psychiatry158(6), 899–905 (2001).
  • Mayberg HS, Brannan SK, Tekell JL et al. Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response. Biol. Psychiatry48(8), 830–843 (2000).
  • Buchsbaum MS, Wu J, Siegel BV et al. Effect of sertraline on regional metabolic rate in patients with affective disorder. Biol. Psychiatry41(1), 15–22 (1997).
  • Liotti M, Mayberg HS, McGinnis S, Brannan SL, Jerabek P. Unmasking disease-specific cerebral blood flow abnormalities: mood challenge in patients with remitted unipolar depression. Am. J. Psychiatry159(11), 1830–1840 (2002).
  • Miller JM, Oquendo MA, Ogden RT, Mann JJ, Parsey RV. Serotonin transporter binding as a possible predictor of one-year remission in major depressive disorder. J. Psychiatr. Res.42(14), 1137–1144 (2008).
  • Mayberg HS, Liotti M, Brannan SK et al. Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness. Am. J. Psychiatry156(5), 675–682 (1999).
  • Drevets WC, Videen TO, Price JL, Preskorn SH, Carmichael ST, Raichle ME. A functional anatomical study of unipolar depression. J. Neurosci.12(9), 3628–3641 (1992).
  • Parsey RV, Oquendo MA, Ogden RT et al. Altered serotonin 1A binding in major depression: a [carbonyl-C-11]WAY100635 positron emission tomography study. Biol. Psychiatry59(2), 106–113 (2006).
  • Goldapple K, Segal Z, Garson C et al. Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy. Arch. Gen. Psychiatry61(1), 34–41 (2004).
  • Kennedy SH, Konarski JZ, Segal ZV et al. Differences in brain glucose metabolism between responders to CBT and venlafaxine in a 16-week randomized controlled trial. Am. J. Psychiatry164(5), 778–788 (2007).
  • Konarski JZ, Kennedy SH, Segal ZV et al. Predictors of nonresponse to cognitive behavioural therapy or venlafaxine using glucose metabolism in major depressive disorder. J. Psychiatry Neurosci.34(3), 175–180 (2009).
  • Liao W, Zhang Z, Pan Z et al. Default mode network abnormalities in mesial temporal lobe epilepsy: a study combining fMRI and DTI. Hum.Brain Mapp. DOI: 10.1002/hbm.21076 (2010) (Epub ahead of print).
  • Bonelli SB, Powell R, Yogarajah M et al. Preoperative amygdala fMRI in temporal lobe epilepsy. Epilepsia50(2), 217–27 (2009).
  • Schlosser RG, Wagner G, Koch K, Dahnke R, Reichenbach JR, Sauer H. Fronto-cingulate effective connectivity in major depression: a study with fMRI and dynamic causal modeling. Neuroimage43(3), 645–655 (2008).
  • Wagner G, Sinsel E, Sobanski T et al. Cortical inefficiency in patients with unipolar depression: an event-related FMRI study with the Stroop task. Biol. Psychiatry59(10), 958–965 (2006).
  • Grimm S, Ernst J, Boesiger P et al. Increased self-focus in major depressive disorder is related to neural abnormalities in subcortical-cortical midline structures. Hum.Brain Mapp.30(8), 2617–2627 (2009).
  • Siegle GJ, Carter CS, Thase ME. Use of FMRI to predict recovery from unipolar depression with cognitive behavior therapy. Am. J. Psychiatry.163(4), 735–738 (2006).
  • Gilliam FG, Maton BM, Martin RC et al. Hippocampal 1H-MRSI correlates with severity of depression symptoms in temporal lobe epilepsy. Neurology68(5), 364–368 (2007).
  • Schmitz EB, Moriarty J, Costa DC, Ring HA, Ell PJ, Trimble MR. Psychiatric profiles and patterns of cerebral blood flow in focal epilepsy: interactions between depression, obsessionality, and perfusion related to the laterality of the epilepsy. J. Neurol. Neurosurg. Psychiatry62(5), 458–463 (1997).
  • Ring HA, Acton PD, Scull D, Costa DC, Gacinovik S, Trimble MR. Patterns of brain activity in patients with epilepsy and depression. Seizure8(7), 390–397 (1999).
  • Davies J, Lloyd KR, Jones IK, Barnes A, Pilowsky LS. Changes in regional cerebral blood flow with venlafaxine in the treatment of major depression. Am. J. Psychiatry.160(2), 374–376 (2003).
  • Mayberg HS, Lewis PJ, Regenold W, Wagner HN Jr. Paralimbic hypoperfusion in unipolar depression. J. Nucl. Med.35(6), 929–934 (1994).
  • Usiskin SC. The role of counselling in an out-patient epilepsy clinic: a three year study. Seizure2(2), 111–114 (1993).
  • Charyton C, Elliott JO, Lu B, Moore JL. The impact of social support on health related quality of life in persons with epilepsy. Epilepsy Behav.16(4), 640–645 (2009).
  • Fournier JC, DeRubeis RJ, Shelton RC, Hollon SD, Amsterdam JD, Gallop R. Prediction of response to medication and cognitive therapy in the treatment of moderate to severe depression. J. Consult. Clin. Psychol.77(4), 775–787 (2009).
  • Gilliam F. Optimizing health outcomes in active epilepsy. Neurology58(8 Suppl. 5), S9–S20 (2002).
  • Shneker BF, Cios JS, Elliott JO. Suicidality, depression screening, and antiepileptic drugs: reaction to the FDA alert. Neurology72(11), 987–991 (2009).
  • Gilliam FG, Barry JJ, Hermann BP, Meador KJ, Vahle V, Kanner AM. Rapid detection of major depression in epilepsy: a multicentre study. Lancet Neurol.5(5), 399–405 (2006).
  • Weissman MM, Neria Y, Gameroff MJ et al. Positive screens for psychiatric disorders in primary care: a long-term follow-up of patients who were not in treatment. Psychiatr. Serv.61(2), 151–159 (2010).
  • US Preventive Services Task Force. Screening for depression in adults: U.S. preventive services task force recommendation statement. Ann. Intern. Med.151(11), 784–792 (2009).
  • Krishnamoorthy ES, Trimble MR, Blumer D. The classification of neuropsychiatric disorders in epilepsy: a proposal by the ILAE Commission on Psychobiology of Epilepsy. Epilepsy Behav.10(3), 349–353 (2007).
  • Goffin K, Dedeurwaerdere S, Van Laere K, Van Paesschen W. Neuronuclear assessment of patients with epilepsy. Semin. Nucl. Med.38(4), 227–239 (2008).

Websites

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.