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Theme: Alzheimer's disease - Review

Is dementia preventable? Focus on Alzheimer’s disease

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Pages 1689-1698 | Published online: 09 Jan 2014

References

  • Vaillant GE, Mukamal K. Successful aging. Am. J. Psychiatry158, 839–847 (2001).
  • Korczyn AD, Vakhapova V. The prevention of the dementia epidemic. J. Neurol. Sci.257, 2–4 (2007).
  • Hort J, O’Brien JT, Gainotti G et al.; on behalf of the EFNS Scientist Panel on Dementia. EFNS guidelines for the diagnosis and management of Alzheimer’s disease. Eur. J. Neurol.17, 1236–1248 (2010).
  • Iqbal K, Grundke-Iqbal I. Alzheimer›s disease, a multifactorial disorder seeking multitherapies. Alzheimers Dement.6, 420–424 (2010).
  • Yeo LH, Horan MA, Jones M, Pendleton N. Perceptions of risk and prevention of dementia in the healthy elderly. Dement. Geriatr. Cogn. Disord.23, 368–371 (2007).
  • Patterson C, Feightner JW, Garcia A, Hsiung GY, MacKnight C, Sadovnick AD. Diagnosis and treatment of dementia: 1. Risk assessment and primary prevention of Alzheimer disease. CMAJ178, 548–556 (2008).
  • Chertkow H. Diagnosis and treatment of dementia: introduction. Introducing a series based on the Third Canadian Consensus Conference on the Diagnosis and Treatment of Dementia. CMAJ178, 316–321 (2008).
  • Fratiglioni L, Winblad B, von Strauss E. Prevention of Alzheimer’s disease and dementia. Major findings from the Kungsholmen Project. Physiol. Behav.92, 98–104 (2007).
  • Middleton LE, Yaffe K. Promising strategies for the prevention of dementia. Arch. Neurol.66, 1210–1215 (2009).
  • Waldstein SR, Giggey PP, Thayer JF, Zonderman AB. Nonlinear relations of blood pressure to cognitive function: the Baltimore Longitudinal Study of Aging. Hypertension45, 374–379 (2005).
  • Burke D, Hickie I, Breakspear M, Götz J. Possibilities for the prevention and treatment of cognitive impairment and dementia. Br. J. Psychiatry190, 371–372 (2007).
  • Wu C, Zhou D, Wen C, Zhang L, Como P, Qiao Y. Relationship between blood pressure and Alzheimer’s disease in Linxian County, China. Life Sci.72, 1125–1133 (2003).
  • Honig LS, Tang MX, Albert S et al. Stroke and the risk of Alzheimer disease. Arch. Neurol.60, 1707–1712 (2003).
  • Spence JD. Carotid intima-media thickness and cognitive decline: what does it mean for prevention of dementia? J. Neurol. Sci.223, 103–105 (2004).
  • Gerhard L, Bergener M, Homayun S. Vascular changes in Alzheimer’s disease. Z. Neurol.201, 43–61 (1972).
  • Knopman DS, Mosley TH, Catellier DJ, Coker LH; Atherosclerosis Risk in Communities Study Brain MRI Study. Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study. Alzheimers Dement.5, 207–214 (2009).
  • Shah RC, Wilson RS, Bienias JL, Arvanitakis Z, Evans DA, Bennett DA. Relation of blood pressure to risk of incident Alzheimer‘s disease and change in global cognitive function in older persons. Neuroepidemiology26, 30–36 (2006).
  • Hebert LE, Scherr PA, Bennett DA et al. Blood pressure and late-AD cognitive function change: a biracial longitudinal population study. Neurology62, 2021–2024 (2004).
  • McGuinness B, Todd S, Passmore P, Bullock R. Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia. Cochrane Database Syst. Rev.CD004034 (2009).
  • Peila R, White LR, Masaki K, Petrovitch H, Launer LJ. Reducing the risk of dementia: efficacy of long-term treatment of hypertension. Stroke37, 1165–1170 (2006).
  • Lithell H, Hansson L, Skoog I et al.; SCOPE Study Group. The study on cognition and prognosis in the elderly (SCOPE): principal results of a randomized double-blind intervention trial. J. Hypertens.21, 875–886 (2003).
  • Tzourio C, Anderson C, Chapman N et al.; PROGRESS Collaborative Group. Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Arch. Intern. Med.163, 1069–1075 (2003).
  • Bosch J, Yusuf S, Pogue J et al.; HOPE Investigators. Heart outcomes prevention evaluation. Use of ramipril in preventing stroke: double blind randomised trial. BMJ324, 699–702 (2002).
  • Fogari R, Mugellini A, Zoppi A et al. of valsartan compared with enalapril on blood pressure and cognitive function in elderly patients with essential hypertension. Eur. J. Clin. Pharmacol.59, 863–868 (2004).
  • Forette F, Seux ML, Staessen JA et al.; Systolic Hypertension in Europe Investigators. The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study. Arch. Intern. Med.162, 2046–2052 (2002).
  • Hanon O, Forette F. Prevention of dementia: lessons from SYST-EUR and PROGRESS. J. Neurol. Sci.226, 71–74 (2004).
  • Li NC, Lee A, Whitmer RA et al. Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis. BMJ340, b5465 (2010).
  • McGuinness B, Todd S, Passmore AP, Bullock R. Systematic review: blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia. J. Neurol. Neurosurg. Psychiatry7, 4–5 (2008).
  • Skoog I. Antihypertensive treatment and dementia prevention. Lancet Neurol.7(8), 664–665 (2008).
  • Schaefer EJ, Bongard V, Beiser AS et al. Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study. Arch. Neurol.63, 1545–1550 (2006).
  • Lim WS, Gammack JK, Van Niekerk J, Dangour AD. Omega 3 fatty acid for the prevention of dementia. Cochrane Database Syst. Rev. (1), CD005379 (2006).
  • Beydoun MA, Kaufman JS, Sloane PD, Heiss G, Ibrahim J. n-3 fatty acids, hypertension and risk of cognitive decline among older adults in the Atherosclerosis Risk in Communities (ARIC) study. Public Health Nutr.11, 17–29 (2008).
  • van de Rest O, Geleijnse JM, Kok FJ et al. Effect of fish oil on cognitive performance in older subjects: a randomized, controlled trial. Neurology71, 430–438 (2008).
  • Fotuhi M, Mohassel P, Yaffe K. Fish consumption, long-chain omega-3 fatty acids and risk of cognitive decline or Alzheimer disease: a complex association. Nat. Clin. Pract. Neurol.5, 140–152 (2009).
  • Luchsinger JA, Mayeux R. Dietary factors and Alzheimer’s disease. Lancet Neurol.3, 579–587 (2004).
  • Panza F, Solfrizzi V, Colacicco AM et al. Mediterranean diet and cognitive decline. Public Health Nutr.7, 959–963 (2004).
  • Scarmeas N, Stern Y, Mayeux R, Manly JJ, Schupf N, Luchsinger JA. Mediterranean diet and mild cognitive impairment. Arch. Neurol.66, 216–225 (2009).
  • Barberger-Gateau P, Raffaitin C, Letenneur L et al. Dietary patterns and risk of dementia: the Three-City cohort study. Neurology69, 1921–1930 (2007).
  • Féart C, Samieri C, Rondeau V et al. Adherence to a Mediterranean diet, cognitive decline, and risk of dementia. JAMA302, 638–648 (2009).
  • Gu Y, Nieves JW, Stern Y, Luchsinger JA, Scarmeas N. Food combination and Alzheimer disease risk: a protective diet. Arch. Neurol.67, 699–706 (2010).
  • Wilson RS, Mendes De Leon CF, Barnes LL et al. Participation in cognitively stimulating activities and risk of incident Alzheimer disease. JAMA287, 742–748 (2002).
  • Wilson RS, Scherr PA, Schneider JA, Tang Y, Bennett DA. Relation of cognitive activity to risk of developing Alzheimer disease. Neurology69, 1911–1920 (2007).
  • Wilson RS, Hebert LE, Scherr PA, Barnes LL, Mendes de Leon CF, Evans DA. Educational attainment and cognitive decline in old age. Neurology72, 460–465 (2009).
  • Valenzuela MJ. Brain reserve and the prevention of dementia. Curr. Opin. Psychiatry21, 296–302 (2008).
  • Ball K, Berch DB, Helmers KF et al.; Advanced Cognitive Training for Independent and Vital Elderly Study Group. Effects of cognitive training interventions with older adults: a randomized controlled trial. JAMA288, 2271–2281 (2002).
  • Willis SL, Tennstedt SL, Marsiske M et al.; ACTIVE Study Group. Long-term effects of cognitive training on everyday functional outcomes in older adults. JAMA296, 2805–2814 (2006).
  • Fritsch T, Smyth KA, McClendon MJ et al. Associations between dementia/mild cognitive impairment and cognitive performance and activity levels in youth. J. Am. Geriatr. Soc.53, 1191–1196 (2005).
  • Geda YE. Physical exercise, cognitive activity, caloric intake, and mild cognitive impairment: the Mayo Clinic study of aging AAN (2010) Abstract S44.004.
  • Madden DJ, Blumenthal JA, Allen PA, Emery CF. Improving aerobic capacity in healthy older adults does not necessarily lead to improved cognitive performance. Psychol. Aging4, 307–320 (1998).
  • Hill RD, Storandt M, Malley M. The impact of long-term exercise training on psychological function in older adults. J. Gerontol.48, 12–17 (1993).
  • Broe GA, Creasey H, Jorm AF et al. Health habits and risk of cognitive impairment and dementia in old age: a prospective study on the effects of exercise, smoking and alcohol consumption. Aust. NZ J. Public Health22, 621–623 (1998).
  • Lytle ME, Vander Bilt J, Pandav RS, Dodge HH, Ganguli M. Exercise level and cognitive decline: the MoVIES project. Alzheimer Dis. Assoc. Disord.18, 57–64 (2004).
  • Yaffe K, Fiocco AJ, Lindquist K et al.; Health ABC Study. Predictors of maintaining cognitive function in older adults: the Health ABC study. Neurology72, 2029–2035 (2009).
  • Achiron A, Kalron A. Physical activity: positive impact on brain plasticity. Harefuah147, 252–255 (2008).
  • Andel R, Crowe M, Pedersen NL, Fratiglioni L, Johansson B, Gatz M. Physical exercise at midAD and risk of dementia three decades later: a population-based study of Swedish twins. J. Gerontol.63, 62–66 (2008).
  • Middleton LE, Mitnitski A, Fallah N, Kirkland SA, Rockwood K. Changes in cognition and mortality in relation to exercise in late AD: a population based study. PLoS One3, e3124 (2008).
  • Brown AK, Liu-Ambrose T, Tate R, Lord SR. The effect of group-based exercise on cognitive performance and mood in seniors residing in intermediate care and self-care retirement facilities: a randomised controlled trial. Br. J. Sports Med.43, 608–614 (2009).
  • Lautenschlager NT, Cox KL, Flicker L et al. Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial. JAMA300, 1027–1037 (2008).
  • Deeny SP, Poeppel D, Zimmerman JB et al. Exercise, APOE, and working memory: MEG and behavioral evidence for benefit of exercise in epsilon4 carriers. Biol. Psychol.78, 179–187 (2008).
  • Sumic A, Michael YL, Carlson NE, Howieson DB, Kaye JA. Physical activity and the risk of dementia in oldest old. J. Aging Health19, 242–259 (2007).
  • Hamer M, Chida Y. Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence. Psychol. Med.39(1), 3–11 (2009).
  • Scarmeas N, Luchsinger JA, Schupf N et al. Physical activity, diet, and risk of Alzheimer disease. JAMA302(6), 627–637 (2009).
  • Dechamps A, Diolez P, Thiaudière E et al. Effects of exercise programs to prevent decline in health-related quality of AD in highly deconditioned institutionalized elderly persons: a randomized controlled trial. Arch. Intern. Med.170, 162–169 (2010).
  • Liu-Ambrose T, Nagamatsu LS, Graf P, Beattie BL, Ashe MC, Handy TC. Resistance training and executive functions: a 12-month randomized controlled trial. Arch. Intern. Med.170, 170–178 (2010).
  • Kemmler W, von Stengel S, Engelke K, Häberle L, Kalender WA. Exercise effects on bone mineral density, falls, coronary risk factors, and health care costs in older women: the randomized controlled Senior Fitness and Prevention (SEFIP) Study. Arch. Intern. Med.170(2), 179–185 (2010).
  • Etgen T, Sander D, Huntgeburth U, Poppert H, Förstl H, Bickel H. Physical activity and incident cognitive impairment in elderly persons: the INVADE study. Arch. Intern. Med.170, 186–193 (2010).
  • Sun Q, Townsend MK, Okereke OI et al. Physical activity at MidAD in relation to successful survival in women at age 70 years or older. Arch. Intern. Med.170, 194–201 (2010).
  • Williamson J, Pahor M. Evidence regarding the benefits of physical exercise. Arch. Intern. Med.170, 124–125 (2010).
  • Manton KC, Gu XL, Ukraintseva SV. Declining prevalence of dementia in the U.S. elderly population. Adv. Gerontol.16, 30–37 (2005).
  • Eriksson PS, Perfilieva E, Björk-Eriksson T et al. Neurogenesis in the adult human hippocampus. Nat. Med.4(11), 1313–1317 (1998).
  • Deng W, Aimone JB, Gage FH. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat. Rev. Neurosci.11, 339–350 (2010).
  • Ritchie K, Carrière I, Ritchie CW, Berr C, Artero S, Ancelin ML. Designing prevention programmes to reduce incidence of dementia: prospective cohort study of modifiable risk factors. BMJ341, c3885 (2010).
  • Kurth T, Logroscino G. Can dementia be prevented? BMJ341, c4201 (2010).

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