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Theme: Alzheimer's disease - Review

Abhorring the vacuum: use of Alzheimer’s disease medications in frontotemporal dementia

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Pages 709-717 | Published online: 09 Jan 2014

References

  • Bei Hu, Ross L, Neuhaus J et al. Off-label medication use in frontotemporal dementia. Am. J. Alzheimers Dis. Other Demen.25(2), 128–133 (2010).
  • Rabinovici GD, Miller BL. Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management. CNS Drugs24(5), 375–398 (2010).
  • Rascovsky KP, Hodges JR, Kipps CM et al. Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions. Alzheimer Dis. Assoc. Disorders21(4), S14–S18 (2007).
  • Neary D, Snowden JS, Gustafson L et al. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology51(6), 1546–1554 (1998).
  • Mackenzie I, Neumann M, Bigio E et al. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathol.119(1), 1–4 (2010).
  • Neumann M, Sampathu DM, Kwong LK et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science314(5796), 130–133 (2006).
  • Neumann M, Rademakers R, Roeber S, Baker M, Kretzschmar HA, Mackenzie IR. A new subtype of frontotemporal lobar degeneration with FUS pathology. Brain132(Pt 11), 2922–2931 (2009).
  • Merrilees J. A model for management of behavioral symptoms in frontotemporal lobar degeneration. Alzheimer Dis. Assoc. Disord.21(4), S64–S69 (2007).
  • Talerico KA, Evans LK. Responding to safety issues in frontotemporal dementias. Neurology56(11 Suppl. 4), S52–S55 (2001).
  • Perry RJ, Miller BL. Behavior and treatment in frontotemporal dementia. Neurology56(11 Suppl. 4), S46–S51 (2001).
  • Mendez MF. Frontotemporal dementia: therapeutic interventions. Front. Neurol. Neurosci.24, 168–178 (2009).
  • Huey ED, Putnam KT, Grafman J. A systematic review of neurotransmitter deficits and treatments in frontotemporal dementia. Neurology66(1), 17–22 (2006).
  • Procter AW, Qurne M, Francis PT. Neurochemical features of frontotemporal dementia. Dement. Geriatr. Cogn. Disord.10(Suppl. 1), 80–84 (1999).
  • Sparks DL, Markesbery WR. Altered serotonergic and cholinergic synaptic markers in Pick’s disease. Arch. Neurol.48(8), 796–799 (1991).
  • Pasquier F, Fukui T, Sarazin M et al. Laboratory investigations and treatment in frontotemporal dementia. Annals Neurol.54(Suppl. 5), S32–S35 (2003).
  • Chow TW, Mendez MF. Goals in symptomatic pharmacologic management of frontotemporal lobar degeneration. Am. J. Alzheimers Dis. Other Demen.17(5), 267–272 (2002).
  • Moretti R, Torre P, Antonello RM, Cazzato G, Bava A. Frontotemporal dementia: paroxetine as a possible treatment of behavior symptoms. A randomized, controlled, open 14-month study. Eur. Neurol.49(1), 13–19 (2003).
  • Deakin JB, Rahman S, Nestor PJ, Hodges JR, Sahakian BJ. Paroxetine does not improve symptoms and impairs cognition in frontotemporal dementia: a double-blind randomized controlled trial. Psychopharmacology172(4), 400–408 (2004).
  • Lebert F, Pasquier F. Trazodone in the treatment of behaviour in frontotemporal dementia. Hum. Psychopharmacol. Clin. Exp.14(4), 279–281 (1999).
  • Bowen D, Procter A, Mann D et al. Imbalance of a serotonergic system in frontotemporal dementia: implication for pharmacotherapy. Psychopharmacology196(4), 603–610 (2008).
  • Curtis RC, Resch DS. Case of pick’s central lobar atrophy with apparent stabilization of cognitive decline after treatment with risperidone. J. Clin. Psychopharmacol.20(3), 384–385 (2000).
  • Moretti R, Torre P, Antonello RM, Cazzato G, Griggio S, Bava A. Olanzapine as a treatment of neuropsychiatric disorders of Alzheimer’s disease and other dementias: a 24-month follow-up of 68 patients. Am. J. Alzheimers Dis. Other Demen.18(4), 205–214 (2003).
  • Pijnenburg YA, Sampson EL, Harvey RJ, Fox NC, Rossor MN. Vulnerability to neuroleptic side effects in frontotemporal lobar degeneration. Int. J. Geriatr. Psychiatry18(1), 67–72 (2003).
  • Wang PS, Schneeweiss S, Avorn J et al. Risk of death in elderly users of conventional vs. atypical antipsychotic medications. N. Engl. J. Med.353(22), 2335–2341 (2005).
  • Moretti R, Torre P, Antonello RM, Cazzato G, Bava A. Effects of selegiline on fronto-temporal dementia: a neuropsychological evaluation. Int. J. Geriatr. Psychiatry17(4), 391–392 (2002).
  • Rahman S, Robbins TW, Hodges JR et al. Methylphenidate (‘Ritalin’) can ameliorate abnormal risk-taking behavior in the frontal variant of frontotemporal dementia. Neuropsychopharmacology31(3), 651–658 (2006).
  • Goforth HW, Konopka L, Primeau M et al. Quantitative electroencephalography in frontotemporal dementia with methylphenidate response: a case study. Clin. EEG Neurosci.35(2), 108–111 (2004).
  • Kerchner GA, Boxer AL. Bapineuzumab. Expert Opin. Biol. Ther.10(7), 1121–1130 (2010).
  • Brunden KR, Trojanowski JQ, Lee VM. Advances in tau-focused drug discovery for Alzheimer’s disease and related tauopathies. Nat. Rev. Drug Discov.8(10), 783–793 (2009).
  • Hansen RA, Gartlehner G, Webb AP, Morgan LC, Moore CG, Jonas DE. Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer’s disease: a systematic review and meta-analysis. Clin. Interv. Aging3(2), 211–225 (2008).
  • Shanks M, Kivipelto M, Bullock R, Lane R. Cholinesterase inhibition: is there evidence for disease-modifying effects? Curr. Med. Res. Opin.25(10), 2439–2446 (2009).
  • Munoz-Torrero D. Acetylcholinesterase inhibitors as disease-modifying therapies for Alzheimer’s disease. Curr. Med. Chem.15(24), 2433–2455 (2008).
  • Hansen LA, Deteresa R, Tobias H, Alford M, Terry RD. Neocortical morphometry and cholinergic neurochemistry in Pick’s disease. Am. J. Pathol.131(3), 507–518 (1988).
  • Cummings JL, Schneider L, Tariot PN, Kershaw PR, Yuan W. Reduction of behavioral disturbances and caregiver distress by galantamine in patients with Alzheimer’s disease. Am. J. Psychiatry161(3), 532–538 (2004).
  • Trinh N-H, Hoblyn J, Mohanty S, Yaffe K. Efficacy of cholinesterase inhibitors in the treatment of neuropsychiatric symptoms and functional impairment in Alzheimer disease: a meta-analysis. JAMA289(2), 210–216 (2003).
  • Lampl Y, Sadeh M, Lorberboym M. Efficacy of acetylcholinesterase inhibitors in frontotemporal dementia. Ann. Pharmacother.38(11), 1967–1968 (2004).
  • Moretti R, Torre P, Antonello RM, Cattaruzza T, Cazzato G, Bava A. Rivastigmine in frontotemporal dementia: an open-label study. Drugs Aging21(14), 931–937 (2004).
  • Knopman DS, Kramer JH, Boeve BF et al. Development of methodology for conducting clinical trials in frontotemporal lobar degeneration. Brain131(Pt 11), 2957–2968 (2008).
  • Kertesz A, Morlog D, Light M et al. Galantamine in frontotemporal dementia and primary progressive aphasia. Dement. Geriatr. Cogn. Disord.25(2), 178–185 (2008).
  • Gorno-Tempini ML, Brambati SM, Ginex V et al. The logopenic/phonological variant of primary progressive aphasia. Neurology71(16), 1227–1234 (2008).
  • Rabinovici GD, Jagust WJ, Furst AJ et al. Aβ amyloid and glucose metabolism in three variants of primary progressive aphasia. Ann. Neurol.64(4), 388–401 (2008).
  • Mendez MF, Shapira JS, McMurtray A, Licht E. Preliminary findings: behavioral worsening on donepezil in patients with frontotemporal dementia. Am. J. Ger. Psychiatry15(1), 84–87 (2007).
  • Boxer AL, Boeve BF. Frontotemporal dementia treatment: current symptomatic therapies and implications of recent genetic, biochemical, and neuroimaging studies. Alzheimer Dis. Assoc. Disord.21(4), S79–S87 (2007).
  • Lomen-Hoerth C, Anderson T, Miller B. The overlap of amyotrophic lateral sclerosis and frontotemporal dementia. Neurology59(7), 1077–1079 (2002).
  • Lomen-Hoerth C, Murphy J, Langmore S, Kramer JH, Olney RK, Miller B. Are amyotrophic lateral sclerosis patients cognitively normal? Neurology60(7), 1094–1097 (2003).
  • van Marum RJ. Update on the use of memantine in Alzheimer’s disease. Neuropsychiatr. Dis. Treat.5, 237–247 (2009).
  • Parsons CG, Stöffler A, Danysz W. Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system – too little activation is bad, too much is even worse. Neuropharmacology53(6), 699–723 (2007).
  • Kerchner G, Kim A, Choi D. Glutamate-mediated excitotoxicity. In: Ionotropic Glutamate Receptors in the CNS. Jonas P, Monyer H (Eds). Springer-Verlag, Berlin, Germany, 443–469 (1999).
  • Lipton SA. Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond. Nat. Rev. Drug Discov.5(2), 160–170 (2006).
  • Olney JW, Farber NB. NMDA antagonists as neurotherapeutic drugs, psychotogens, neurotoxins, and research tools for studying schizophrenia. Neuropsychopharmacology13(4), 335–345 (1995).
  • Selkoe DJ. Alzheimer’s disease is a synaptic failure. Science298(5594), 789–791 (2002).
  • Palop JJ, Chin J, Mucke L. A network dysfunction perspective on neurodegenerative diseases. Nature443(7113), 768–773 (2006).
  • Wilcock GK, Ballard CG, Cooper JA, Loft H. Memantine for agitation/aggression and psychosis in moderately severe to severe Alzheimer’s disease: a pooled analysis of 3 studies. J. Clin. Psychiatry69(3), 341–348 (2008).
  • Franco KN, Messinger-Rapport B. Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence. J. Am. Med. Dir. Assoc.7(3), 201–202 (2006).
  • Gauthier S, Wirth Y, Möbius HJ. Effects of memantine on behavioural symptoms in Alzheimer’s disease patients: an analysis of the Neuropsychiatric Inventory (NPI) data of two randomised, controlled studies. Int. J. Geriatr. Psychiatry20(5), 459–464 (2005).
  • Cummings JL, Schneider E, Tariot PN, Graham SM, for the Memantine MEM-MD-02 Study Group. Behavioral effects of memantine in Alzheimer disease patients receiving donepezil treatment. Neurology67(1), 57–63 (2006).
  • Swanberg MM. Memantine for behavioral disturbances in frontotemporal dementia: a case series. Alzheimer Dis. Assoc. Dis.21(2), 164–166 (2007).
  • Diehl-Schmid J, Förstl H, Perneczky R, Pohl C, Kurz A. A 6-month, open-label study of memantine in patients with frontotemporal dementia. Int. J. Geriatr. Psychiatry23(7), 754–759 (2008).
  • Boxer AL, Lipton AM, Womack K et al. An open-label study of memantine treatment in 3 subtypes of frontotemporal lobar degeneration. Alzheimer Dis. Assoc. Disord.23(3), 211–217 (2009).
  • Matsuoka Y, Jouroukhin Y, Gray AJ et al. A neuronal microtubule-interacting agent, NAPVSIPQ, reduces tau pathology and enhances cognitive function in a mouse model of Alzheimer’s disease. J. Pharmacol. Exp. Ther.325(1), 146–153 (2008).
  • Wischik C, Staff R. Challenges in the conduct of disease-modifying trials in AD: Practical experience from a Phase 2 trial of TAU-aggregation inhibitor therapy. J. Nutr. Health Aging13(4), 367–369 (2009).
  • Vossel KA, Miller BL. New approaches to the treatment of frontotemporal lobar degeneration. Curr. Opin. Neurol.21(6), 708–716 (2008).
  • Trojanowski JQ, Duff K, Fillit H et al. New directions for frontotemporal dementia drug discovery. Alzheimers Dement.4(2), 89–93 (2008).
  • Stamelou M, de Silva R, Arias-Carrion O et al. Rational therapeutic approaches to progressive supranuclear palsy. Brain133(Pt 6), 1578–1590 (2010).
  • Cruts M, Gijselinck I, van der Zee J et al. Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21. Nature442(7105), 920–924 (2006).
  • Baker M, Mackenzie IR, Pickering-Brown SM et al. Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature442(7105), 916–919 (2006).
  • Jiao J, Herl LD, Farese RV, Gao FB. MicroRNA-29b regulates the expression level of human progranulin, a secreted glycoprotein implicated in frontotemporal dementia. PLoS One5(5), e10551 (2010).
  • Knopman DS, Jack CR Jr, Kramer JH et al. Brain and ventricular volumetric changes in frontotemporal lobar degeneration over 1 year. Neurology72(21), 1843–1849 (2009).

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