Generating flavivirus vaccine candidates by modulating interferon sensitivity

References

• Liang JJ, Liao CL, Liao JT, Lee YL, Lin YL. A Japanese encephalitis virus vaccine candidate strain is attenuated by decreasing its interferon antagonistic ability. Vaccine27(21), 2746–2754 (2009).
   Google Scholar
• Lindenbach BD, Thiel HJ, Rice CM. Flaviviridae: the viruses and their replication. In: Fields Virology. Knipe DM, Howley PM (Eds). Lippincott-Raven Publishers, PA, USA (2007).
   Google Scholar
• Mackenzie JS. Emerging zoonotic encephalitis viruses: lessons from southeast Asia and Oceania. J. Neurovirol.11(5), 434–440 (2005).
   PubMed Web of Science ®Google Scholar
• Takeuchi O, Akira S. Innate immunity to virus infection. Immunol. Rev.227(1), 75–86 (2009).
   PubMed Web of Science ®Google Scholar
• Randall RE, Goodbourn S. Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J. Gen. Virol.89(Pt 1), 1–47 (2008).
   PubMed Web of Science ®Google Scholar
• Du Z, Wei L, Murti A et al. Non-conventional signal transduction by type 1 interferons: the NF-κB pathway. J. Cell. Biochem.102(5), 1087–1094 (2007).
   PubMed Web of Science ®Google Scholar
• Fredericksen BL, Gale M Jr. West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling. J. Virol.80(6), 2913–2923 (2006).
   PubMedGoogle Scholar
• Chang TH, Liao CL, Lin YL. Flavivirus induces interferon-β gene expression through a pathway involving RIG-I-dependent IRF-3 and PI3K-dependent NF-κB activation. Microbes Infect.8(1), 157–171 (2006).
   PubMed Web of Science ®Google Scholar
• Liu WJ, Wang XJ, Mokhonov VV, Shi PY, Randall R, Khromykh AA. Inhibition of interferon signaling by the New York 99 strain and Kunjin subtype of West Nile virus involves blockage of STAT1 and STAT2 activation by nonstructural proteins. J. Virol.79(3), 1934–1942 (2005).
   PubMed Web of Science ®Google Scholar
• Jones M, Davidson A, Hibbert L et al. Dengue virus inhibits α interferon signaling by reducing STAT2 expression. J. Virol.79(9), 5414–5420 (2005).
   PubMed Web of Science ®Google Scholar
• Guo JT, Hayashi J, Seeger C. West Nile virus inhibits the signal transduction pathway of α interferon. J. Virol.79(3), 1343–1350 (2005).
   PubMedGoogle Scholar
• Monath TP. Treatment of yellow fever. Antiviral Res.78(1), 116–124 (2008).
   PubMed Web of Science ®Google Scholar
• Tsai TF. New initiatives for the control of Japanese encephalitis by vaccination: minutes of a WHO/CVI meeting, Bangkok, Thailand, 13–15 October 1998. Vaccine18(Suppl. 2), 1–25 (2000).
   PubMed Web of Science ®Google Scholar
• Lin YL, Liao CL, Yeh CT et al. A highly attenuated strain of Japanese encephalitis virus induces a protective immune response in mice. Virus Res.44(1), 45–56 (1996).
   Google Scholar
• Chen LK, Lin YL, Liao CL et al. Generation and characterization of organ-tropism mutants of Japanese encephalitis virus in vivo and in vitro. Virology223(1), 79–88 (1996).
   Google Scholar
• Lin RJ, Liao CL, Lin E, Lin YL. Blocking of the α interferon-induced Jak–Stat signaling pathway by Japanese encephalitis virus infection. J. Virol.78(17), 9285–9294 (2004).
   PubMedGoogle Scholar
• Lin RJ, Chang BL, Yu HP, Liao CL, Lin YL. Blocking of interferon-induced Jak–Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism. J. Virol.80(12), 5908–5918 (2006).
   PubMed Web of Science ®Google Scholar
• Katze MG, Fornek JL, Palermo RE, Walters KA, Korth MJ. Innate immune modulation by RNA viruses: emerging insights from functional genomics. Nat. Rev. Immunol.8(8), 644–654 (2008).
   PubMed Web of Science ®Google Scholar
• Asselin-Paturel C, Brizard G, Chemin K et al. Type I interferon dependence of plasmacytoid dendritic cell activation and migration. J. Exp. Med.201(7), 1157–1167 (2005).
   PubMed Web of Science ®Google Scholar
• Luft T, Pang KC, Thomas E et al. Type I IFNs enhance the terminal differentiation of dendritic cells. J. Immunol.161(4), 1947–1953 (1998).
   PubMed Web of Science ®Google Scholar
• Shrestha B, Diamond MS. Role of CD8+ T cells in control of West Nile virus infection. J. Virol.78(15), 8312–8321 (2004).
   PubMed Web of Science ®Google Scholar
• Wang Y, Lobigs M, Lee E, Mullbacher A. CD8+ T cells mediate recovery and immunopathology in West Nile virus encephalitis. J. Virol.77(24), 13323–13334 (2003).
   PubMed Web of Science ®Google Scholar
• Lefeuvre A, Contamin H, Decelle T et al. Host-cell interaction of attenuated and wild-type strains of yellow fever virus can be differentiated at early stages of hepatocyte infection. Microbes Infect.8(6), 1530–1538 (2006).
   Google Scholar
• Liu WJ, Wang XJ, Clark DC, Lobigs M, Hall RA, Khromykh AA. A single amino acid substitution in the West Nile virus nonstructural protein NS2A disables its ability to inhibit α/β interferon induction and attenuates virus virulence in mice. J. Virol.80(5), 2396–2404 (2006).
   PubMed Web of Science ®Google Scholar
• Bolt G, Berg K, Blixenkrone-Moller M. Measles virus-induced modulation of host-cell gene expression. J. Gen. Virol.83(Pt 5), 1157–1165 (2002).
   Google Scholar
• Schioler KL, Samuel M, Wai KL. Vaccines for preventing Japanese encephalitis. Cochrane Database Syst. Rev. (3), CD004263 (2007).
   PubMedGoogle Scholar
• Okabe N. Background of recent JE vaccine issues. Uirusu55(2), 303–306 (2005).
   Google Scholar
• Pugachev KV, Guirakhoo F, Monath TP. New developments in flavivirus vaccines with special attention to yellow fever. Curr. Opin. Infect. Dis.18(5), 387–394 (2005).
   PubMed Web of Science ®Google Scholar