Advanced search
Publication Cover
Acta Cardiologica Volume 59, 2004 - Issue 3
Submit an article Journal homepage
8
Views
0
CrossRef citations to date
0
Altmetric
Articles

Short-term effect of atorvastatin on ischaemic threshold in hypercholesterolaemic patients with stable ischaemic heart disease

Marc J. ClaeysCardiology, Hospital Brain l’Alleud, Rue Wayez 35, 1420 Brain l’Alleud, Belgium.Correspondence[email protected]
,
Bernard CosynsCardiology, Hospital Brain l’Alleud, Rue Wayez 35, 1420 Brain l’Alleud, Belgium.
,
Etienne HofferCardiology, Hôpital La Citadelle, Bd Du 12ème de Ligne 1, 4000 Liège, Belgium.
,
Marc CarlierCardiology, Hôpital St Joseph Gilly, Rue de la Duchère 6, 6060 Gilly, Belgium.
,
Luc MissaultCardiology, AZ St Jan, Ruddershove 10, 8000 Brugge, Belgium.
,
Frank CoolsCardiology, AZ KLINA, Augustijnslei 100, 2930 Brasschaat, Belgium.
,
Antoine De MeesterCardiology, Hôpital Jolimont, Rue Ferrer 159, 7100 Haine St Paul, Belgium.
,
Paul VermeerschCardiology, AZ Middelheim, Lindendreef 1, 2020 Antwerpen, Belgium.
,
Eric GobinCardiology, CHU Sart Tilman, Bat B35, 4000 Liège, Belgium.
,
Brigitte DewitCardiology, Clinique St Michel –Europe, Rue de Linthout 150, 1040Bruxelles, Belgium.
& For The Belgian Young Cardiologists’ Club show all
Pages 269-274 | Received 12 May 2003, Accepted 23 Sep 2003, Published online: 23 May 2017

References

  • Adams MR, Kinlay S, Blake GJ, Orford JL, Ganz P, Selwyn AP. Atherogenic lipids and endothelial dysfunction: mecha-nisms in the genesis of ischemic syndromes. Annu Rev Med 2000; 51: 149–67.
  • Kaufmann P, Matter C, Mandinov L, Frielingsdorf J, Seiler C, Hess OM. High level of cholesterol increases coronary vasomotor tone during exercise. Coron Artery Dis 2000; 11(6): 459–66.
  • Sessa WC. Can modulation of endothelial nitric oxide synthase explain the vasculoprotective actions of statins? Trends Mol Med 2001; 7(5): 189–91.
  • O’Driscoll G, Green D, Taylor RR. Simvastatin, an HMG-coenzyme A reductase inhibitor, improves endothelial func-tion within 1 month. Circulation 1997; 95(5): 1126–31.
  • Dupuis J, Tardif JC, Cernacek P, Theroux P. Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes. The RECIFE (reduction of cholesterol in ischemia and function of the endothelium) trial. Circula-tion 1999; 99(25): 3227–33.
  • Marchesi S, Lupattelli G, Siepi D, Schillaci G, Vaudo G, Roscini AR, Sinzinger H, Mannarino E. Short-term ator-vastatin treatment improves endothelial function in hyper-cholesterolemic women. J Cardiovasc Pharmacol 2000; 36(5): 617–21.
  • Laufs U, Wassmann S, Hilgers S, Ribaudo N, Bohm M, Nickenig G. Rapid effects on vascular function after initia-tion and withdrawal of atorvastatin in healthy, normocho-lesterolemic men. Am J Cardiol 2001; 88(11): 1306–7.
  • Masumoto A, Hirooka Y, Hironaga K, Eshima K, Setoguchi S, Egashira K, Takeshita A. Effect of pravastatin on endothe-lial function in patients with coronary artery disease (cho-lesterol-independent effect of pravastatin). Am J Cardiol 2001; 88(11): 1291–4.
  • Tamai O, Matsuoka H, Itabe H, Wada Y, Kohno K, Imaizumi T. Single LDL apheresis improves endothelium-dependent vasodilatation in hypercholesterolemic humans. Circulation 1997; 95(1): 76–82.
  • Nawrocki JW, Weiss SR, Davidson MH, Sprecher DL, Schwartz SL, Lupien PJ, Jones PH, Haber HE, Black DM. Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor. Arterioscler Thromb Vasc Biol 1995; 15(5): 678–82.
  • Schrott H, Fereshetian AG, Knopp RH, Bays H, Jones PH, Littlejohn TW, III, McLain R, Black DM. A multicenter, placebo-controlled, dose-ranging study of atorvastatin. J Cardiovasc Pharmacol Ther 1998; 3(2): 119–24.
  • Wassmann S, Laufs U, Baumer AT, Muller K, Ahlbory K, Linz W, Itter G, Rosen R, Bohm M, Nickenig G. HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced produc-tion of reactive oxygen species. Hypertension 2001; 37(6): 1450–7.
  • Perticone F, Ceravolo R, Maio R, Cloro C, Candigliota M, Scozzafava A, Mongiardo A, Mastroroberto P, Chello M, Mattioli PL. Effects of atorvastatin and vitamin C on endothelial function of hypercholesterolemic patients. Atherosclerosis 2000; 152(2): 511–8.
  • Ramires JA, Sposito AC, Mansur AP, Coelho OR, Maran-hao M, Cesar LA. Cholesterol lowering with statins reduces exercise-induced myocardial ischemia in hypercholesterolemic patients with coronary artery disease. Am J Cardiol 2001; 88(10): 1134–8.
  • Prasad A, Mincemoyer R, Quyyumi AA. Anti-ischemic effects of angiotensin-converting enzyme inhibition in hyper-tension. J Am Coll Cardiol 2001; 38(4): 1116–22.
  • Cannon RO, III. Cardiovascular benefit of cholesterol-lowering therapy: does improved endothelial vasodilator function matter? Circulation 2000; 102(8): 820–2.
  • Quyyumi AA. Does acute improvement of endothelial dysfunction in coronary artery disease improve myocardial ischemia? A double-blind comparison of parenteral D-and L-arginine. J Am Coll Cardiol 1998; 32(4): 904–11.
  • Egashira K, Hirooka Y, Kai H, Sugimachi M, Suzuki S, Inou T, Takeshita A. Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vaso-motion in patients with hypercholesterolemia. Circulation 1994; 89(6): 2519–24.
  • Treasure CB, Klein JL, Weintraub WS, Talley JD, Stillabower ME, Kosinski AS, Zhang J, Boccuzzi SJ, Cedarholm JC, Alexander RW. Beneficial effects of choles-terol-lowering therapy on the coronary endothelium in patients with coronary artery disease. N Engl J Med 1995; 332(8): 481–7.
  • Andrews TC, Raby K, Barry J, Naimi CL, Allred E, Ganz P, Selwyn AP. Effect of cholesterol reduction on myocardial ischemia in patients with coronary disease. Circulation 1997; 95(2): 324–8.
  • Mansur AP, Serrano CV, Jr, Nicolau JC, Cesar LA, Ramires JA. Effect of cholesterol lowering treatment on positive exercise tests in patients with hypercholesterolaemia and normal coronary angiograms. Heart 1999; 82(6): 689–93.
  • van Boven AJ, Jukema JW, Zwinderman AH, Crijns HJ, Lie KI, Bruschke AV. Reduction of transient myocardial ischemia with pravastatin in addition to the conventional treatment in patients with angina pectoris. REGRESS Study Group. Circulation 1996; 94(7): 1503–5.
  • Pitt B, Waters D, Brown WV, van Boven AJ, Schwartz L, Title LM, Eisenberg D, Shurzinske L, McCormick LS. Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease. Atorvastatin versus revas-cularization treatment Investigators. N Engl J Med 1999; 341(2): 70–6.
  • Vasa M, Fichtlscherer S, Adler K, Aicher A, Martin H, Zeiher AM, Dimmeler S. Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coro-nary artery disease. Circulation 2001; 103(24): 2885–90.
  • Dujovne CA, Harris WS, Altman R, Overhiser RW, Black DM. Effect of atorvastatin on hemorheologic-hemostatic parameters and serum fibrinogen levels in hyperlipidemic patients. Am J Cardiol 2000; 85(3): 350–3.
  • Marraccini P, Levantesi D, Michelassi C, Dalle VM, L’Abbate A. Individual variability in symptoms, ischemic threshold and cardiovascular efficiency during exercise test-ing in patients with effort angina. Can J Cardiol 1989; 5(4): 222–8.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

A worldwide pioneer in biotechnology.
Novartis. Your partner in Heart Failure & Atherosclerosis >>

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.