Advanced search
Publication Cover
Acta Cardiologica Volume 59, 2004 - Issue 5
Submit an article Journal homepage
6
Views
0
CrossRef citations to date
0
Altmetric
Articles

Changes of homocysteine levels and arterial endothelial function in patients with high risk of coronary artery disease after 6-month folic acid supplementation

Hangyuan GuoDepartment of Cardiology, Huayu Hospital, China Medical University, Shaoxing 312030, China;First Department of Internal Medicine, Medical College, Fukui University, Fukui 910-1193, JapanCorrespondence[email protected] (Hangyuan)
,
Jong-Dae LeeFirst Department of Internal Medicine, Medical College, Fukui University, Fukui 910-1193, Japan
,
Yangbo XingDepartment of Cardiology, Huayu Hospital, China Medical University, Shaoxing 312030, China
,
Jianfeng ChengNew York State Psychiatric Institute and Columbia University, NY 10032, U.S.A.
,
Takanori UedaFirst Department of Internal Medicine, Medical College, Fukui University, Fukui 910-1193, Japan
,
Kiyohiro ToyodaFirst Department of Internal Medicine, Medical College, Fukui University, Fukui 910-1193, Japan
&
Tooru GeshiFirst Department of Internal Medicine, Medical College, Fukui University, Fukui 910-1193, Japan
 show all
Pages 503-506 | Received 28 Jul 2003, Accepted 12 Jan 2004, Published online: 23 May 2017

References

  • Carson NAJ, Neill DW. Metabolic abnormalities detected in a survey of mentally backward individuals in Northern Ireland. Arch Disease Child 1962; 37: 505–13.
  • McCully KS. Vascular pathology of homocysteinemia: impli-cations for the pathogenesis of arteriosclerosis. Am J Path 1969; 56: 111–28.
  • Graham IM, Daly IE, Refsum HM, Robinson K, Brattstrom LE, Ueland PM, Palma-Reis RJ, Boers GH, Sheahan RG, Israelsson B. Plasma homocysteine as a risk factor for vascular disease: The European concerted Action Project. JAMA 1997; 277: 1775–81.
  • Clark R, Daly L, Robinson K, Naughten E, Cahalane S, Fowler B, Graham I. Hyperhomocysteinemia: An indepen-dent risk factor for vascular disease. N Engl J Med 1991; 324: 1149–55.
  • Ubbink JB, Hayward VW Bissbort S. Rapid high-perfor-mance liquid chromatographic assay for total homocysteine levels in human serum. J Chromat 1991; 565: 441–6.
  • Virdis A, Ghiadoni L, Salvetti G, Versari D, Taddei S. Salvett A. Hyperhomocyst(e)inemia: is this a novel risk factor in hypertension? J Nephrol 2002; 15: 414–21.
  • Woo KS, Chook P, Lolin YI, Cheung AS, Chan LT, Sun YY, Sanderson JE, Metreweli Celermajer DS. Hyper-homocysteinemia is a risk factor for arterial endothelial dys-function in humans. Circulation 1997; 96: 2542–4.
  • Stampfer MJ, Malinow MR, Willett WC, Newcomer LM, Upson B, Ullmann D, Tishler PV, Hennekens CH. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA 1992; 268: 877–81.
  • Frinkelstein JD. The metabolism of homocysteine: Pathways and regulation. Eur J Pediatr 1998; 157: 40–4.
  • Malinow MR, Due11 PB, Hess DL, Anderson PH, Kruger WD, Philipson BE, Gluckman RA, Block PC, Upson BM. Reduction of plasma homocysteine levels by breakfast cereal fortified with folic acid in patients with coro-nary heart disease. N Engl J Med 1998; 338: 1009–15.
  • Woo KS, Chook P, Cheung AS, Fung WH, Qiao M, Lolin YI, Thomas GN, Sanderson JE, Metreweli C, Celer-majer DS. Long-term improvement in homocysteine levels and arterial endothelial function after 1-year folic acid sup-plementation. Am J Med 2002; 112: 535–39.
  • Willems FF, Aengevaeren WR, Boers GH, Blom HJ, Verheugt FW. Coronary endothelial function in hyperho-mocysteinemia: improvement after treatment with folic acid and cobalamin in patients with coronary artery disease. J Am Coll Cardiol 2002; 40: 766–72.
  • O’Grady HL, Leahy A, McCormick PH, Fitzgerald P, Kelly CK, Bouchier-Hayes DJ. Oral folic acid improves endothelial dysfunction in cigarette smokers. J Surg Res 2002; 106: 342–5.
  • Gottsater A, Forsblad J, Mattiasson I, Lindgarde F. Decreas-ing plasma endothelin-1 and unchanged plasma neopterin during folate supplementation in hyperhomocysteinemia. Int Angiol 2002; 21: 158–64.
  • Van Wersch JW, Janssens Y, Zandvoort JA, Folic acid, vitamin B(12), and homocysteine in smoking and non-smoking pregnant women. Eur J Obstet Gynecol Reprod Biol 2002; 103: 18–21.
  • Holven KB, Aukrust P, Holm T, Ose L, Nenseter MS. Folic acid treatment reduces chemokine release from peripheral blood mononuclear cells in hyperhomocysteinemic subjects. Arterioscler Thromb Vasc Biol 2002; 22: 699–703.
  • Mayer 0, Filipovsky J, Hromadka M, Svobodova V, Racek J, Mayer 0 Jr, Stehlik P, Trefil, Zarybnicka M. Treat-ment of hyperhomocysteinemia with folic acid: effects on homocysteine levels, coagulation status, and oxidative stress markers. J Cardiovasc Pharmacol 2002; 39: 851–7.
  • el-Swefy SE, Ali SI, Asker ME, Mohamed HE. Hyperho-mocysteinaemia and cardiovascular risk in female ovariec-tomized rats: role of folic acid and hormone replacement therapy. J Pharm Pharmacol 2002; 54: 391–7.
  • Venn BJ, Mann JI, Williams SM, Riddell LJ, Chisholm A, Harper MJ, Aitken W, Rossaak JI. Assessment of three levels of folic acid on serum folate and plasma homocys-teine: a randomised placebo-controlled double-blind dietary intervention trial. Eur J Clin Nutr 2002; 56: 748–54.
  • Sato Y, Kaji M, Kondo I, Yoshida H, Satoh K, Metoki N, Hyperhomocysteinemia in Japanese patients with convales-cent stage ischemic stroke: effect of combined therapy with folic acid and mecobalamine. J Neurol Sci 2002; 202: 65–8.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

A worldwide pioneer in biotechnology.
Bristol Myers Squibb – symposium on hypertrophic cardiomyopathy.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.