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Articles

Comparison of the effects of trimetazidine and diltiazem on exercise performance in patients with coronary heart disease. The Turkish trimetazidine study (TTS)

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Pages 644-650 | Received 06 Feb 2004, Accepted 10 Jun 2004, Published online: 23 May 2017

References

  • Gibbons RJ, Chatterjee K, Levy D, Daley J, Douglas JS, Film SD, Gardin JM, Grunwald MA, Lytle BW, O’Rourke RA, Schafer WP, Williams SV, Ritchie JL, Cheitlin MD, Eagle KA, Gardner TJ, Garson A Jr, Russel RO, Ryan TJ, Smith SC Jr: ACC/AHA/ACP-ASIM Guidelines for the Management of Patients With Chronic Sta-ble Angina. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With Chronic Stable Angina). J Am Coll Cardiol 1999; 33 (7): 2092–7.
  • Jackson G. The place of metabolic agents in the manage-ment of stable angina pectoris. Rev Port Cardiol 1999; 18 Suppl 4: I V23–27.
  • Rizzon P, Iliceto S, Marangelli V. Metabolic approach to myocardial ischemia. A novel therapeutic strategy for patients with coronary artery disease. Cardiologia 1995; 40 (10): 717–20.
  • de Leiris J, Opie LH. Cellular antiischemic agents. In: Car-diovascular Drug Therapy 2nd edition, 1996. Ed. FH Messerli, WB Saunders Company, Pennsylvania: p. 1594–1603.
  • Lavanchy N, Martin J, Rossi A. Anti-ischaemic effects of trimetazidine: 31P-NMR spectroscopy in the isolated rat heart. Arch Int Pharmacodyn Ther 1987; 286: 97–110.
  • Kantor PF, Lucien A, Kozak R, Lopaschuk GD. The antianginal drug trimetazidine shifts cardiac energy metab-olism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. Circ Res 2000; 86: 487–9.
  • Renaud JF. Internal pH, Na+ and Ca2+ regulation by trimetazidine during cardiac cell acidosis. Cardiovasc Drugs Ther 1988; 1: 677–86.
  • Maupoil V, Rochette L, Tabard A, Clauser P, Harpey C. Direct measurement of free radical generation in isolated rat heart by electron paramagnetic resonance spectroscopy: effect of trimetazidine. Adv Exp Med Biol 1990; 264: 377–82.
  • Maridonneau-Parini K, Harpey C. Effects of trimetazidine on membrane damage induced by oxygen free radicals in human red cells. Br J Clin Pharm 1985; 20: 148–51.
  • Williams FM, Tanda K, Kus M. Trimetazidine inhibits neu-trophil accumulation after myocardial ischemia and reper-fusion in rabbits. J Cardiovasc Pharmacol 1993; 22: 828–33.
  • McClellan KJ, Plosker GL. Trimetazidine - A review of its use in stable angina pectoris and other coronary conditions. Drugs 1999; 58 (1): 143–57.
  • Sellier P, Adouin P, Payen B, Corona P, Duong TC, Our-back P. Acute effects of trimetazidine evaluated by exercise testing. Eur J Clin Pharmacol 1987; 33: 205–7.
  • Dalla Volta S, Maraglino G, Della Valentina B, Viena P, Desideri A. Comparison of trimetazidine in stable effort angina: a double-blind cross-over study. Cardiovasc Drug Ther 1990; 4: 853–60.
  • Detry JM, Sellier P, Pennaforte S, Cokkinos D, Dargie H, Mathes P. Trimetazidine: a new concept in the treatment of angina. Comparison with propranolol in patients with sta-ble angina. Br J Clin Pharmacol 1994; 37: 279–88.
  • Michaelides AP, Vysoulis GP, Bonoris PE, Psaros TK, Papadopoulos PD, Toutouzas PK. Beneficial effects of trimetazidine in patients with stable angina under beta-block-ers. Cardiovasc Drug Ther 1987; 1: 268. [abstract].
  • Levy S, The Group of South of France Investigators. Com-bination therapy of trimetazidine with diltiazem in patients with coronary artery disease. Am J Cardiol 1995; 76: 12B–16B.
  • Kober G, Buck T, Sievert H, Vallbracht C. Myocardial pro-tection during percutaneous transluminal coronary angio-plasty: effects of trimetazidine. Eur Heart J 1992; 13: 1109–15.
  • Steg PG, Grollier G, Gallay P, Morice MC, Kempf C, Laperche T, Arnaud P, SeHier P, Bourguignon C, Harpey C. A randomized double-blind trial of trimetazidine as adjunc-tive therapy to primary PTCA for acute myocardial infarc-tion: evidence for improved myocardial reperfusion from ST-segment analysis [abstract]. Eur Heart J 1998; 19 (Abstract Suppl.): 365.
  • Fabiani JN, Ponzio 0, Emerit I, Massonet Castel S, Paris M, Chevalier P, Jebara V, Carpentier A. Cardioprotective effect of trimetazidine during coronary artery graft surgery. Car-diovasc Surg 1992; 33: 486–91.
  • Vedrinne JM, Vedrinne C, Bompard D, Lehot JJ, Boissel JP, Champsaur G. Myocardial protection during coronary artery bypass graft surgery: a randomized, double-blind, placebo-controlled study with trimetazidine. Anesth Ana1g 1996; 82: 712–8.
  • Dalla-Volta S, Maraglino G, Della-Valentina P, Viena P. Desideri A. Comparison of trimetazidine with nifedipine in effort angina: a double-blind crossover study. Cardiovasc Drugs Ther 1990(4); suppl 4: 853–9.
  • Detry JM, Leclercq PJ. Trimetazidine European Multicen-ter Study versus propranolol in stable angina pectoris: con-tribution of Holter electrocardiographic ambulatory moni-toring. Am J Cardiol 1995(24); 76(6): 8B–11B.
  • Pornin M, Harpey C, Allal J, SeHier P, Ourbak P. Effects of trimetazidine on systemic hemodynamics in patients with coronary artery disease. Mol Gel Cardiol 1990; 22 (suppl 22): 150.
  • Nalbantgil S, Altintig A, Yilmaz H, Nalbantgil I, Onder R. The effect of trimetazidine in the treatment of microvascu-lar angina. Int J Angiol 1999; 8: 40–3.
  • Cross HR. Trimetazidine for stable angina pectoris. Exp Opin Pharmacother 2001; 2(5): 857–75.
  • Manchanda SC, Krishnaswami S. Combination treatment with trimetazidine and diltiazem in stable angina pectoris. Heart 1997; 78: 353–7.
  • Manchanda SC. Treatment of stable angina with low dose diltiazem in combination with the metabolic agent trimetazi-dine. Int J Cardiol 2003; 88: 83–9.
  • Brochier M, Demange J, Ducloux G, Monpere C, Warin JF. Value of the combination of trimetazidine and a calcium inhibitor in the treatment of chronic coronary insufficiency. Double-blind controlled study versus placebo [in French]. Ann Cardiol Angeiol (Paris) 1986; 35: 49–56.
  • Michaelides AP, Vyssoulis GP, Bonoris PE, Psaros TH, Papadopoulos PD, Toutouzas PK. Beneficial effects of trimetazidine in men with stable angina under beta blocker treatment. Curr Ther Res 1989; 46: 565–6.
  • Michaelides AP, Spiropoulos K, Dimopoulos K. Antiangi-nal efficacy of the combination of trimetazidine-propranolol compared with isosorbide dinitrate-propranolol in patients with stable angina. Clin Drug Invest 1997; 13: 8–14.

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