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Acta Cardiologica Volume 62, 2007 - Issue 5
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Original Articles

The signalling of AT2 and the influence on the collagen metabolism of AT2 receptor in adult rat cardiac fibroblasts

Xiao-Ying JiangDepartment of Physiology and Pathophysiology, College of Medicine, Xi’an Jiaotong University, Xi’an, 710061, Shaanxi, China.
,
Guang-Dao GaoDepartment of Physiology and Pathophysiology, College of Medicine, Xi’an Jiaotong University, Xi’an, 710061, Shaanxi, China.Correspondence[email protected]
,
Xiao-Jun DuBaker Heart Research Institute, Melbourne, Victoria 8008, Australia.
,
Juan ZhouDepartment of Physiology and Pathophysiology, College of Medicine, Xi’an Jiaotong University, Xi’an, 710061, Shaanxi, China.
,
Xin-Feng WangDepartment of Physiology and Pathophysiology, College of Medicine, Xi’an Jiaotong University, Xi’an, 710061, Shaanxi, China.
&
Yuan-Xi LinDepartment of Physiology and Pathophysiology, College of Medicine, Xi’an Jiaotong University, Xi’an, 710061, Shaanxi, China.
Pages 429-438 | Received 27 Feb 2007, Accepted 24 Aug 2007, Published online: 23 May 2017

References

  • Varagic J, Frohlich ED. Local cardiac renin-angiotensin system: Hypertension and cardiac failure. J Mol Cell Car-diol 2002; 34: 1435–42.
  • Dubey RK, Gillespie DG, Mi Z, Jackson EK. Exogenous and endogenous adenosine inhibits fetal calf serum-induced growth of rat cardiac fibroblasts: Role of A2B receptors. Circulation 1997; 96: 2656–66.
  • Lijnen PJ, Petrov VV. Role of intracardiac renin-angiotensin-aldosterone system in extracellular matrix remodeling. Meth-ods Find Exp Clin Pharmacol 2003; 25: 541–64.
  • Seeland U, Haeuseler C, Hinriches R, Rosenkranz S, Pfitzner T, Scharffetter-Kochanek K, Bohm M. Myocardial fibrosis in transforming growth factor-f31 (TGF-f31) transgenic mice is associated with inhibition of interstitial collagenase. Eur J Clin Invest 2002; 32: 295–303.
  • Sarkar S, Vellaichamy E, Young D, Sen S. Influence of cytokines and growth factors in Ang II-mediated collagen upregulation by fibroblasts in rats: role of myocytes. Am J Physiol Heart Circ Physiol 2004; 287: H107–17.
  • Steckelings UM, Kaschina E, Unger T. The AT2 receptor - A matter of love and hate. Peptides 2005; 26: 1401–9.
  • Gross V, Obst M, Luft FC. Insights into angiotensin II receptor function through AT2 receptor knockout mice. Acta Physiol Scand 2004; 181: 487–94.
  • Zhu YC, Zhu YZ, Lu N, Wang MJ, Wang YX and Yao T. Role of angiotensin AT1 and AT2 receptors in cardiac hyper-trophy and cardiac remodeling. Clin Exp Pharmacol Phys-iol 2003; 30: 911–8.
  • Oishi Y, Ozono R, Yano Y, Teranishi Y, Akishita M, Hori-uchi M, Oshima T, Kambe M. Cardioprotective role of AT2 receptor in postinfarctong left ventricular remodeling. Hypertension 2003; 41: 814–8.
  • Kurisu S, Ozono R, Oshima T, Kambe M, Ishida T, Sugino H, Matsuura H, Chayama K, Teranishi Y, Iba O, Amano K, Matsubara H. Cardiac angiotensin II type 2 receptor acti-vates the kinin/NO system and inhibits fibrosis. Hypertension 2003; 41: 99–107.
  • Jones ES, Black MJ, Widdop RE. Angiotensin AT2 recep-tor contributes to cardiovascular remodelling of aged SHR during chronic AT1 receptor blockade. J Mol Cell Cardiol 2004; 37: 1023–30.
  • D’Amore A, Black MJ, Thomas WG. The AT2 receptor causes constitutive growth of cardiomyocytes and does not antagonize AT1 receptor-mediated hypertrophy. Hyperten-sion 2005; 46: 1347–54.
  • Berk BC. Angiotensin II receptors and angiotensin II-stim-ulated signal transduction. Heart Failure Reviews 1998; 3: 87–99.
  • Csikos T, Chung O, Unger T. Role of angiotensin II in hyper-tension-induced cardiac hypertrophy and failure. Heart Fail-ure Reviews 1999; 3: 159–68.
  • Hou M, Pantev E, Moller S, Erlinge D, Edvinsson L. Angiotensin II type 1 receptors stimulate protein synthesis in human cardiac fibroblasts via a Ca2 +-sensitive PKC-dependent tyrosine kinase pathway. Acta Physiol Scand 2000; 168: 301–9.
  • Abbasi S, Su B, Kellems RE, Yang J, Xia Y. The essential role of MEKK3 signaling in angiotensin II-induced cal-cineurin/nuclear factor of activated T-cells activation. J Biol Chem 2005; 280: 36737–46.
  • Pulakat L, Rahman S, Gray A, Knowle D, Gavini N. Roles of the intracellular regions of angiotensin II receptor AT2 in mediating reduction of intracellular cGMP levels. Cell Signal 2005; 17: 395–404.
  • Ritter 0, Schuh K, Brede M, Rothlein N, Burkard N, Hein L, Neyses L. AT2 receptor activation regulates myocardial eNOS expression via the calcineurin-NF-AT pathway. FASEB J2002; 16: 283–5.
  • Andresen BT, Shome K, Jackson EK, Romero GG. AT2 receptors cross-talk with AT1 receptors through a nitric oxide and RhoA dependent mechanism resulting in decreased phospholipase D activity. Am J Physiol Renal Physiol 2005; 288: F763–70.
  • Fritz RD, Radziwill G. The scaffold protein CNK1 inter-acts with the angiotensin II type 2 receptor. Biochem Biophys Res Commun 2005; 338: 1906–12.
  • Kumar D, Menon V, Ford WR, Clanachan AS, Jugdutt BI. Effect of angiotensin II type 2 receptor blockade on mito-gen activated protein kinases during myocardial ischemia-reperfusion. Mol Cell Bio 2004; 258: 211–8.
  • Seta K, Sadoshima J. Phosphorylation of tyrosine 319 of the angiotensin II type 1 receptor mediates angiotensin II-induced trans-activation of the epidermal growth factor receptor. J Biol Chem 2003; 278: 9019–26.
  • Nouet S, Amzallag N, Li JM, Louis S, Seitz I, Cui TX, Alleaume AM, Di Benedetto M, Boden C, Masson M, Stros-berg AD, Horiuchi M, Couraud PO, Nahmias C. Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP. J Biol Chem 2004; 279: 28989–97.
  • Chen K, Chen SW, Li DY, Zhang XJ, Mehta JL. Angiotensin II regulation of collagen type I expression in cardiac fibrob-lasts-modulation by PPAR-gamma ligand pioglitazone. Hypertension 2004; 44: 655–61.
  • Lijnen PJ, Petrov VV, Fagard RH. Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors. J Renin Angiotensin Aldosterone Syst 2001; 2: 117–22.
  • Diez J. Emerging role of matrix metalloproteinases in the pathophysiology of cardiac diseases. Eur J Clin Invest 2002; 32: 291–4.

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