1,371
Views
0
CrossRef citations to date
0
Altmetric
Commentary

Artificial Sweetener is a Growing Threat for Metabolic Syndrome: Why is Extra Attention required?

ORCID Icon, &
Article: FSO880 | Received 29 May 2023, Accepted 08 Jun 2023, Published online: 23 Jun 2023

Reference

  • RochlaniY , PothineniNV , KovelamudiS , MehtaJL. Metabolic syndrome: pathophysiology, management, and modulation by natural compounds. Ther. Adv. Cardiovasc. Dis.11(8), 215–225 (2017).
  • ZatteraleF , LongoM , NaderiJet al.Chronic adipose tissue inflammation linking obesity to insulin resistance and Type 2 diabetes. 10https://doi.org/10.3389/fphys.2019.01607(2020).
  • SwarupS , GoyalA , GrigorovaY , ZeltserR. Metabolic syndrome. In: StatPearls.StatPearls Publishing Copyright © 2023, StatPearls Publishing LLC, FL, USA (2023).
  • GrundySM , CleemanJI , DanielsSRet al.Diagnosis and management of the metabolic syndrome. 112(17), 2735–2752 (2005).
  • LiangX , OrB , TsoiMF , CheungCL , CheungBMY. Prevalence of metabolic syndrome in the United States National Health and Nutrition Examination Survey 2011–18. Postgrad. Med. J.https://doi.org/10.1093/postmj/qgad008 (2023).
  • SinghSA , DhanasekaranD , GanamuraliN , PL , SabarathinamS. Junk food-induced obesity-a growing threat to youngsters during the pandemic. Obes. Med.26, 100364 (2021).
  • ChattopadhyayS , RaychaudhuriU , ChakrabortyR. Artificial sweeteners - a review. J. Food Sci. Technol.51(4), 611–621 (2014).
  • CzarneckaK , PilarzA , RogutAet al.Aspartame-true or false? Narrative review of safety analysis of general use in products. Nutrients13(6), (2021).
  • BianX , ChiL , GaoB , TuP , RuH , LuK. The artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice. PloS ONE12(6), e0178426 (2017).
  • OtabeA , FujiedaT , MasuyamaT , UbukataK , LeeC. Advantame – an overview of the toxicity data. Food Cheem. Toxicol.49, S2–S7 (2011).
  • Scientific Opinion on the safety of advantame for the proposed uses as a food additive. EFSA J.11, (2013).
  • RegnatK , MachRL , Mach-AignerAR. Erythritol as sweetener-wherefrom and whereto?Appl. Microbiol. Biotechnol.102(2), 587–595 (2018).
  • WitkowskiM , NemetI , AlamriHet al.The artificial sweetener erythritol and cardiovascular event risk. Nature Med.29(3), 710–718 (2023).
  • DietvorstJ , LondesboroughJ , SteensmaHY. Maltotriose utilization in lager yeast strains: MTT1 encodes a maltotriose transporter. 22(10), 775–788 (2005).
  • MarcosA , Serra-MajemL , Pérez-JiménezF , PascualV , TinahonesFJ , EstruchR. Moderate consumption of beer and its effects on cardiovascular and metabolic health: an updated review of recent scientific evidence. Nutrients13(3), (2021).
  • ChiL , BianX , GaoBet al.Effects of the artificial sweetener neotame on the gut microbiome and fecal metabolites in mice. Molecules (Basel, Switzerland)23(2), (2018).
  • PeteliukV , RybchukL , BayliakM , StoreyKB , LushchakO. Natural sweetener Stevia rebaudiana: functionalities, health benefits and potential risks. EXCLI J.20, 1412–1430 (2021).
  • ElangoD , RajendranK , Vander Laan Let al.Raffinose family oligosaccharides: friend or foe for human and plant health?Front. Plant Sci.13https://doi.org/10.3389/fpls.2022.829118 (2022).
  • AzeezOH , AlkassSY , PersikeDS. Long-term saccharin consumption and increased risk of obesity, diabetes, hepatic dysfunction, and renal impairment in rats. Medicina (Kaunas, Lithuania)55(10), (2019).
  • SchiffmanSS , RotherKI. Sucralose, a synthetic organochlorine sweetener: overview of biological issues. J. Toxicol. Environ. Health B Crit. Rev.16(7), 399–451 (2013).