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Future Science OA Volume 10, 2024 - Issue 1
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Preliminary Communication

GC-MS analysis of an ethanolic extract of Ocimum species: a network pharmacology analysis insight towards obesity

Priyadharshini Gnanamurthy1 Department of Genetic Engineering, School of Bioengineering, College of Engineering & Technology, SRM Institute of Science & Technology, Kattankulathur, Chennai, Tamil Nadu, 603203, India
,
Manoj K Narasimhan1 Department of Genetic Engineering, School of Bioengineering, College of Engineering & Technology, SRM Institute of Science & Technology, Kattankulathur, Chennai, Tamil Nadu, 603203, IndiaCorrespondence[email protected]
&
Sarvesh Sabarathinam2 Drug Testing Laboratory, Interdisciplinary Institute of Indian System of Medicine (IIISM), SRM Institute of Science & Technology, SRM IST, Kattankulathur, Chennai, Tamil Nadu, 603203, IndiaCorrespondence[email protected]
Article: FSO940 | Received 19 Sep 2023, Accepted 10 Nov 2023, Published online: 10 Jan 2024

References

  • Dharsono HDA, Putri SA, Kurnia D, Dudi D, Satari MH. Ocimum species: a review on chemical constituents and antibacterial activity. 27(19), 6350 (2022).
  • Antora RA, Salleh RM. Antihyperglycemic effect of Ocimum plants: a short review. Asian Pacific J. Tropical Biomed. 7(8), 755–759 (2017).
  • Sethi J, Sood S, Seth S, Talwar A. Evaluation of hypoglycemic and antioxidant effect ofOcimum sanctum. Indian J. Clinical Biochem. 19(2), 152–155 (2004).
  • Wang M, Cantrell CL, Mathews ST, Paudel P, Lee J, Mentreddy SR. Agronomy, chemical analysis, and antidiabetic activity of basil (Ocimum species). ACS Food Sci. Technol. 2(8), 1243–1256 (2022).
  • Noor ZI, Ahmed D, Rehman HM et al. In vitro antidiabetic, anti-obesity and antioxidant analysis of Ocimum basilicum aerial biomass and in silico molecular docking simulations with alpha-amylase and lipase enzymes. 8(4), 92 (2019).
  • Hopkins AL. Network pharmacology: the next paradigm in drug discovery. Nature Chem. Biol. 4(11), 682–690 (2008).
  • Pant R, Firmal P, Shah VK, Alam A, Chattopadhyay S. Epigenetic regulation of adipogenesis in development of metabolic syndrome. Front Cell Developmental Biol. 8, 619888 (2020).
  • Wu F-Y, Yin R-X. Recent progress in epigenetics of obesity. Diabetol. Metab. Syndr. 14(1), 171 (2022).
  • Sabarathinam S, Rajappan Chandra SK, Satheesh S. Network pharmacology based pharmacokinetic assessment and evaluation of the therapeutic potential of catechin derivatives as a potential myostatin inhibitor: a special view on Sarcopenic Obesity. Nat Prod Res. 17, 1–5 (2023).
  • Sabarathinam S, Ganamurali N. Chalcones reloaded: an integration of network pharmacology and molecular docking for type 2 diabetes therapy. J. Biomol. Struct. Dynamics 41, 1–13 (2023).
  • Sabarathinam S, Satheesh S, Raja A. A computer-aided insight into the identification of significant therapeutic flavone as a promising agent for sarcopenic obesity. Nat Prod Res 1–6 (2023).
  • Venkatesh VS, Grossmann M, Zajac JD, Davey RA. The role of the androgen receptor in the pathogenesis of obesity and its utility as a target for obesity treatments. Obesity Rev. 23(6), e13429 (2022).
  • Sabarathinam S, Ganamurali N. Chalcones reloaded: an integration of network pharmacology and molecular docking for type 2 diabetes therapy. J. Biomol. Structure Dynamics 41, 1–13 (2023).
  • Sabarathinam S, Rajappan Chandra SK, Satheesh S. Network pharmacology based pharmacokinetic assessment and evaluation of the therapeutic potential of catechin derivatives as a potential myostatin inhibitor: a special view on Sarcopenic Obesity. Natural Product Res. 1–5 (2023).
  • Sabarathinam S, Satheesh S, Ganamurali N, Dhanasekaran D, Raja A. Drug designing and toxicity screening of halogen and nitrogen-augmented catechin in sarcopenic obesity. Natural Product Res. 1–6 (2023).
  • Sabarathinam S, Satheesh S, Raja A. A computer-aided insight into the identification of significant therapeutic flavone as a promising agent for sarcopenic obesity. Natural Product Res. 17, 1–6 (2023).
  • Ezeani C, Ezenyi I, Okoye T, Okoli C. Ocimum basilicum extract exhibits antidiabetic effects via inhibition of hepatic glucose mobilization and carbohydrate metabolizing enzymes. J. Intercultural Ethnopharmacol. 6(1), 22–28 (2017).
  • Khalil HE, Abdelwahab MF, Emeka PM et al. Ameliorative Effect of Ocimum forskolei Benth on Diabetic, Apoptotic, and Adipogenic Biomarkers of Diabetic Rats and 3T3-L1 Fibroblasts Assisted by In Silico Approach. 27(9), 2800 (2022).

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