141
Views
8
CrossRef citations to date
0
Altmetric
Review

Impact of semaphorin expression on prognostic characteristics in breast cancer

, , &
Pages 79-88 | Published online: 31 May 2018

References

  • SiegelRLMillerKDJemalACancer statistics, 2016CA Cancer J Clin201666173026742998
  • Nwabo KamdjeAHSeke EtetPFVecchioLMullerJMKramperaMLukongKESignaling pathways in breast cancer: therapeutic targeting of the microenvironmentCell Signal201426122843285625093804
  • BaskinYYigitbasiTClinical proteomics of breast cancerCurr Genomics201011752853621532837
  • SørlieTPerouCMTibshiraniRGene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implicationsProc Natl Acad Sci USA20019819108691087411553815
  • StatonCAShawLAValluruMExpression of class 3 semaphorins and their receptors in human breast neoplasiaHistopathology201159227428221884206
  • MalikMFSatherleyLKDaviesELYeLJiangWGExpression of semaphorin 3C in breast cancer and its impact on adhesion and invasion of breast cancer cellsAnticancer Res20163631281128626977026
  • KolodkinALMatthesDJGoodmanCSThe semaphorin genes encode a family of transmembrane and secreted growth cone guidance moleculesCell1993757138913998269517
  • CapparucciaLTamagnoneLSemaphorin signaling in cancer cells and in cells of the tumor microenvironment–two sides of a coinJ Cell Sci2009122111723173619461072
  • NeufeldGKesslerOThe semaphorins: versatile regulators of tumour progression and tumour angiogenesisNat Rev Cancer20088863264518580951
  • MishraRKumarDTomarDChakrabortyGKumarSKunduGCThe potential of class 3 semaphorins as both targets and therapeutics in cancerExpert Opin Ther Targets201519342744225434284
  • MishraRThoratDSoundararajanGSemaphorin 3A upregulates FOXO 3a-dependent MelCAM expression leading to attenuation of breast tumor growth and angiogenesisOncogene201534121584159524727891
  • AppletonBAWuPMaloneyJStructural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF bindingEMBO J200726234902491217989695
  • ParkerMWLinkugelADVander KooiCWEffect of C-terminal sequence on competitive semaphorin binding to neuropilin-1J Mol Biol2013425224405441423871893
  • Castro-RiveraERanSThorpePMinnaJDSemaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effectProc Natl Acad Sci USA200410131114321143715273288
  • AllegraMZaragkouliasAVorgiaESemaphorin-7a reverses the ERF-induced inhibition of EMT in Ras-dependent mouse mammary epithelial cellsMol Biol Cell201223193873388122875994
  • Cole-HealyZVerganiPHunterKBrownNJReedMWStatonCAThe relationship between semaphorin 3C and microvessel density in the progression of breast and oral neoplasiaExp Mol Pathol2015991192425910410
  • BenderRJMac GabhannFExpression of VEGF and semaphorin genes define subgroups of triple negative breast cancerPloS One201385e6178823667446
  • MalikMFYeLJiangWGReduced expression of semaphorin 4D and plexin-B in breast cancer is associated with poorer prognosis and the potential linkage with oestrogen receptorOncol Rep20153421049105726035216
  • GoodmanCSKolodkinALLuoYPüschelAWRaperJAUnified nomenclature for the semaphorins/collapsinsCell199997555155210367884
  • GherardiELoveCAEsnoufRMJonesEYThe sema domainCurr Opin Struct Biol200414666967815582390
  • KoppelAMFeinerLKobayashiHRaperJAA 70 amino acid region within the semaphorin domain activates specific cellular response of semaphorin family membersNeuron19971935315379331346
  • TakahashiTStrittmatterSMPlexina1 autoinhibition by the plexin sema domainNeuron200129242943911239433
  • Kong-BeltranMStamosJWickramasingheDThe Sema domain of Met is necessary for receptor dimerization and activationCancer Cell200461758415261143
  • TamagnoneLEmerging role of semaphorins as major regulatory signals and potential therapeutic targets in cancerCancer Cell201222214515222897846
  • ChangKKarnadAZhaoSFreemanJWRoles of c-Met and RON kinases in tumor progression and their potential as therapeutic targetsOncotarget201563507351825784650
  • BorkPDoerksTSpringerTASnelBDomains in plexins: links to integrins and transcription factorsTrends Biochem Sci199924726126310390613
  • BasileJRHolmbeckKBuggeTHGutkindJSMT1-MMP controls tumor-induced angiogenesis through the release of semaphorin 4DJ Biol Chem200728296899690517204469
  • MessinaAGiacobiniPSemaphorin signaling in the development and function of the gonadotropin hormone-releasing hormone systemFront Endocrinol20134133
  • HeZTessier-LavigneMNeuropilin is a receptor for the axonal chemorepellent Semaphorin IIICell19979047397519288753
  • TamagnoneLArtigianiSChenHPlexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebratesCell1999991718010520995
  • JanssenBJRobinsonRAPérez-BrangulíFStructural basis of semaphorin-plexin signallingNature201046773191118112220877282
  • OinumaIIshikawaYKatohHNegishiMThe Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-RasScience2004305568586286515297673
  • KolodkinALGintyDDSteering clear of semaphorins: neuropilins sound the retreatNeuron1997196115911629427240
  • SokerSTakashimaSMiaoHQNeufeldGKlagsbrunMNeuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factorCell19989267357459529250
  • Pellet-ManyCFrankelPJiaHZacharyINeuropilins: structure, function and role in diseaseBiochem J2008411221122618363553
  • YazdaniUTermanJRThe semaphorinsGenome Biol20067321116584533
  • TakahashiTFournierANakamuraFPlexin-neuropilin-1 complexes form functional semaphorin-3A receptorsCell1999991596910520994
  • CasazzaAFinisguerraVCapparucciaLSema3E–Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in miceJ Clin Invest201012082684269820664171
  • MasudaKFuruyamaTTakaharaMFujiokaSKurinamiHInagakiSSema4D stimulates axonal outgrowth of embryonic DRG sensory neuronesGenes Cells20049982182915330859
  • DengSHirschbergAWorzfeldTPlexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivoJ Neurosci200727236333634717554007
  • ArtigianiSConrottoPFazzariPPlexin-B3 is a functional receptor for semaphorin 5AEMBO Rep20045771071415218527
  • PanHWanamiLSDissanayakeTRBachelderREAutocrine sema - phorin3A stimulates alpha2 beta1 integrin expression/function in breast tumor cellsBreast Cancer Res Treat2009118119720518787945
  • GehlerSCompereFVMillerAMSemaphorin 3A increases FAK phosphorylation at focal adhesions to modulate MDA-MB-231 cell migration and spreading on different substratum concentrationsInt J Breast Cancer20172017961973428182100
  • Guttmann-RavivNShraga-HeledNVarshavskyAGuimaraes-SternbergCKesslerONeufeldGSemaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosisJ Biol Chem200728236262942630517569671
  • AcevedoLMBarillasSWeisSMGöthertJRChereshDASemaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factorBlood200811152674268018180379
  • ShenWWChenWGLiuFZBreast cancer cells promote osteoblastic differentiation via Sema 3A signaling pathway in vitroInt J Clin Exp Pathol2015821584158325973043
  • Castro-RiveraERanSBrekkenRAMinnaJDSemaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cellsCancer Res200868208295830318922901
  • ShahiPWangCYChouJGATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasisOncogene201736405567557528581515
  • ZhuXZhangXYeZSilencing of semaphorin 3C suppresses cell proliferation and migration in MCF-7 breast cancer cellsOncol Lett20171455913591729113226
  • MumblatYKesslerOIlanNNeufeldGFull-length semaphorin-3C is an inhibitor of tumor lymphangiogenesis and metastasisCancer Res201575112177218625808871
  • EsselensCMalapeiraJColoméNThe cleavage of semaphorin 3C induced by ADAMTS1 promotes cell migrationJ Biol Chem201028542463247319915008
  • XuXZhaoZGuoSIncreased semaphorin 3c expression promotes tumor growth and metastasis in pancreatic ductal adenocarcinoma by activating the ERK1/2 signaling pathwayCancer Lett2017397122228315433
  • LuchinoJHocineMAmoureuxMCSemaphorin 3E suppresses tumor cell death triggered by the plexin D1 dependence receptor in metastatic breast cancersCancer Cell201324567368524139859
  • WeiJCYangJLiuDTumor-associated lymphatic endothelial cells promote lymphatic metastasis by highly expressing and secreting SEMA4CClin Cancer Res201723121422427401250
  • YangYHBuhamrahASchneiderASemaphorin 4d promotes skeletal metastasis in breast cancerPLoS One2016112e015015126910109
  • SwierczJMWorzfeldTOffermannsSErbB-2 and met reciprocally regulate cellular signaling via plexin-B1J Biol Chem200828341893190118025083
  • Ch’ngESKumanogohARoles of Sema4D and Plexin-B1 in tumor progressionMol Cancer20109125120858260
  • WorzfeldTSwierczJMLoosoMStraubBKSivarajKKOffermannsSErbB-2 signals through Plexin-B1 to promote breast cancer metastasisJ Clin Invest201212241296130522378040
  • BlackSANelsonACGuruleNJFutscherBWLyonsTRSemaphorin 7a exerts pleiotropic effects to promote breast tumor progressionOncogene201635395170517827065336
  • Garcia-AreasRLibrerosSAmatSSemaphorin7A promotes tumor growth and exerts a pro-angiogenic effect in macrophages of mammary tumor-bearing miceFront Physiol201451724550834
  • SchneiderBPMillerKDAngiogenesis of breast cancerJ Clin Oncol20052381782179015755986
  • ConleySJGheordunescuEKakaralaPAntiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxiaProc Natl Acad Sci USA201210982784278922308314
  • LiuTJSunBCZhaoXLCD133+ cells with cancer stem cell characteristics associates with vasculogenic mimicry in triple-negative breast cancerOncogene201332554455322469978
  • CasazzaAFuXJohanssonISystemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor modelsArterioscler Thromb Vasc Biol201131474174921205984
  • JiangHChenCSunQThe role of semaphorin 4D in tumor development and angiogenesis in human breast cancerOnco Targets Ther201695737575027729799
  • SierraJRCorsoSCaioneLTumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophagesJ Exp Med200820571673168518559453
  • SeyfriedTNHuysentruytLCOn the origin of cancer metastasisCrit Rev Oncog2013181–2437323237552
  • SinghASettlemanJEEMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancerOncogene201029344741475120531305
  • XuZChenWGSunJChenPChuTWHypoxia inhibits the expression of semaphorin 3A in breast cancer cells and regulates the differentiation of preosteoblast cellsTumor2016361212981306
  • NasarrePConstantinBRouhaudLSemaphorin SEMA3F and VEGF have opposing effects on cell attachment and spreadingNeoplasia200351839212659673
  • XiongGWangCEversBMZhouBPXuRRORα suppresses breast tumor invasion by inducing SEMA3F expressionCancer Res20127271728173922350413
  • ChristensenCAmbartsumianNGilestroGProteolytic processing converts the repelling signal Sema3E into an inducer of invasive growth and lung metastasisCancer Res200565146167617716024618
  • Garcia-AreasRLibrerosSSimoesMSuppression of tumor-derived Semaphorin 7A and genetic ablation of host-derived Semaphorin 7A impairs tumor progression in a murine model of advanced breast carcinomaInt J Oncol20175151395140429048670
  • ChenYZhangLLiuWExpression of semaphorin4C (Sema4C) in breast cancer, endometrial cancer and prostate cancer and its clinical significanceChin J Clin Oncol2010379507511
  • WuMHanLShiYDevelopment and characterization of a novel method for the analysis of gene expression patterns in lymphatic endothelial cells derived from primary breast tissuesJ Cancer Res Clin Oncol2010136686387219936789
  • YangQWangYLuXMiR-125b regulates epithelial-mesenchymal transition via targeting Sema4C in paclitaxel-resistant breast cancer cellsOncotarget2015653268327925605244
  • EvansEEJonasonASBusslerHAntibody blockade of semaphorin 4D promotes immune infiltration into tumor and enhances response to other immunomodulatory therapiesCancer Immunol Res20153668970125614511
  • RodyAHoltrichUGaetjeRPoor outcome in Estrogen receptor–positive breast cancers predicted by loss of Plexin B1Clin Cancer Res20071341115112217317819
  • RodyAKarnTRuckhäberleELoss of Plexin B1 is highly prognostic in low proliferating ER positive breast cancers–results of a large scale microarray analysisEur J Cancer2009453405413
  • ChenDLiYWangLJiaoKSEMA6D expression and patient survival in breast invasive carcinomaInt J breast cancer2015201553972125973277