70
Views
12
CrossRef citations to date
0
Altmetric
Review

Dormancy in breast cancer

, , , , , & show all
Pages 183-191 | Published online: 05 Dec 2012

References

  • AshworthTRA case of cancer in which cells similar to those in tumors were seen in the blood after deathAust Med J186914146149
  • BraunSVoglFDNaumeBA pooled analysis of bone marrow micrometastasis in breast cancerN Engl J Med2005353879380216120859
  • BeckerSSolomayerEBecker-PergolaGWallwienerDFehmTPrimary systemic therapy does not eradicate disseminated tumor cells in breast cancer patientsBreast Cancer Res Treat20071062239243 Epub January 27, 200717260094
  • JanniWRackBSchindlbeckCThe persistence of isolated tumor cells in bone marrow from patients with breast carcinoma predicts an increased risk for recurrenceCancer2005103588489115666325
  • CristofanilliMBuddGTEllisMJCirculating tumor cells, disease progression, and survival in metastatic breast cancerN Engl J Med2004351878179115317891
  • RackBKSchindlbeckCAndergassenUUse of circulating tumor cells (CTC) in peripheral blood of breast cancer patients before and after adjuvant chemotherapy to predict risk for relapse: The SUCCESS trial. ASCO Annual Meeting 2010 [abstract]J Clin Oncol201028Suppl 15s1003
  • LiottaLAKleinermanJSaidelGMQuantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantationCancer Res197434599710044841969
  • ButlerTPGullinoPMQuantitation of cell shedding into efferent blood of mammary adenocarcinomaCancer Res19753535125161090362
  • MehesGWittAKubistaEAmbrosPFCirculating breast cancer cells are frequently apoptoticAm J Pathol20011591172011438448
  • LarsonCJMorenoJGPientaKJApoptosis of circulating tumor cells in prostate cancer patientsCytometry A2004621465315472900
  • FidlerIJMetastasis: Quantitative analysis of distribution and fate of tumor emboli labeled with 125 I-5-Iodo-2′-desoxyuridineJ Natl Cancer Inst1970457737825513503
  • FrischSMScreatonRAAnoikis mechanismsCurr Opin Cell Biol200113555556211544023
  • LiottaLASaidelGMKleinermanJStochastic model of metastases formationBiometrics1976323535550963169
  • LiottaLASaidelMGKleinermanJThe significance of hematogenous tumor cell clumps in the metastatic processCancer Res19763638898941253177
  • BanysMKrawczykNBeckerSThe influence of removal of primary tumor on incidence and phenotype of circulating tumor cells in primary breast cancerBreast Cancer Res Treat20121321121129 Epub May 12, 201121562707
  • KragDNAshikagaTMossTJBreast cancer cells in the blood: a pilot studyBreast J19995635435811348313
  • LuzziKJMacdonaldICSchmidtEEMultistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastasesAm J Pathol199815338658739736035
  • CameronMDSchmidtEEKerkvlietNTemporal progression of metastasis in lung: cell survival, dormancy, and location dependence of metastatic inefficiencyCancer Res20006092541254610811137
  • KienastYVon BaumgartenLFuhrmannMReal-time imaging reveals the single steps of brain metastasis formationNat Med201016111612220023634
  • SleemanJPNazarenkoIThieleWDo all roads lead to Rome? Routes to metastasis developmentInt J Cancer2011128112511252621365648
  • PagetSDistribution of secondary growths in cancer of the breastLancet18891571
  • PsailaBLydenDThe metastatic niche: adapting the foreign soilNat Rev Cancer20099428529319308068
  • KaplanRNRibaRDZacharoulisSVEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic nicheNature2005438706982082716341007
  • ErlerJTWeaverVMThree-dimensional context regulation of metastasisClin Exp Metastasis2009261354918814043
  • KaplanRNPsailaBLydenDBone marrow cells in the ‘pre-metastatic niche’: within bone and beyondCancer Metastasis Rev200625452152917186383
  • DemicheliRAbbattistaAMiceliRValagussaPBonadonnaGTime distribution of the recurrence risk for breast cancer patients undergoing mastectomy: further support about the concept of tumor dormancyBreast Cancer Res Treat19964121771858944336
  • PocockSJGoreSMKerrGRLong term survival analysis: the curability of breast cancerStat Med198212931047187092
  • KarrisonTGFergusonDJMeierPDormancy of mammary carcinoma after mastectomyJ Natl Cancer Inst199991180859890174
  • WillisRAThe Spread of Tumors in the Human BodyLondonJ&A Churchill1934
  • MengSTripathyDFrenkelEPCirculating tumor cells in patients with breast cancer dormancyClin Cancer Res200410248152816215623589
  • HolmgrenLO’ReillyMSFolkmanJDormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppressionNat Med1995121491537585012
  • MorganTMLangePHPorterMPDisseminated tumor cells in prostate cancer patients after radical prostatectomy and without evidence of disease predicts biochemical recurrenceClin Cancer Res200915267768319147774
  • GoodisonSKawaiKHiharaJProlonged dormancy and site-specific growth potential of cancer cells spontaneously disseminated from nonmetastatic breast tumors as revealed by labeling with green fuorescent proteinClin Cancer Res2003910 Pt 13808381414506175
  • WikmanHVessellaRPantelKCancer micrometastasis and tumour dormancyAPMIS20081167–875477018834417
  • BeckerSBecker-PergolaGWallwienerDSolomayerEFFehmTDetection of cytokeratin-positive cells in the bone marrow of breast cancer patients undergoing adjuvant therapyBreast Cancer Res Treat2006971919616319975
  • FrischSMFrancisHDisruption of epithelial cell-matrix interactions induces apoptosisJ Cell Biol199412446196268106557
  • FehmTMuellerVMarchesRTumor cell dormancy: implications for the biology and treatment of breast cancerAPMIS20081167–874275318834416
  • Aguirre-GhisoJAModels, mechanisms and clinical evidence for cancer dormancyNat Rev Cancer200771183484617957189
  • HusseinOKomarovaSVBreast cancer at bone metastatic sites: recent discoveries and treatment targetsJ Cell Commun Signal200152859921484191
  • TownsonJLChambersAFDormancy of solitary metastatic cellsCell Cycle20065161744175016861927
  • WhiteDERaymentJHMullerWJAddressing the role of cell adhesion in tumor cell dormancyCell Cycle20065161756175916880738
  • RanganathanACAdamAPAguirre-GhisoJAOpposing roles of mitogenic and stress signaling pathways in the induction of cancer dormancyCell Cycle20065161799180716929185
  • Aguirre GhisoJAKovalskiKOssowskiLTumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signalingJ Cell Biol199914718910410508858
  • NaumovGNMacdonaldICWeinmeisterPMPersistence of solitary mammary carcinoma cells in a secondary site: a possible contributor to dormancyCancer Res20026272162216811929839
  • FisherJLThomas-MudgeRJElliottJOsteoprotegerin overexpression by breast cancer cells enhances orthotopic and osseous tumor growth and contrasts with that delivered therapeuticallyCancer Res20066673620362816585187
  • HolenICrossSSNeville-WebbeHLOsteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo – a role in tumour cell survival?Breast Cancer Res Treat200592320721516155791
  • Neville-WebbeHLCrossNAEatonCLOsteoprotegerin (OPG) produced by bone marrow stromal cells protects breast cancer cells from TRAIL-induced apoptosisBreast Cancer Res Treat200486326927915567943
  • ZhangXHWangQGeraldWLatent bone metastasis in breast cancer tied to Src-dependent survival signalsCancer Cell2009161677819573813
  • IndraccoloSStievanoLMinuzzoSInterruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironmentProc Natl Acad Sci U S A2006103114216422116537511
  • NaumovGNBenderEZurakowskiDA model of human tumor dormancy: an angiogenic switch from the nonangiogenic phenotypeJ Natl Cancer Inst200698531632516507828
  • KleinCABlankensteinTJSchmidt-KittlerOGenetic heterogeneity of single disseminated tumour cells in minimal residual cancerLancet2002360933468368912241875
  • BarkanDKleinmanHSimmonsJLInhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeletonCancer Res200868156241625018676848
  • UhrJWPantelKControversies in clinical cancer dormancyProc Natl Acad Sci U S A201110830123961240021746894
  • BalicMLinHYoungLMost early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotypeClin Cancer Res200612195615562117020963
  • HolenIColemanREAnti-tumour activity of bisphosphonates in preclinical models of breast cancerBreast Cancer Res201012621421176176
  • FournierPGStresingVEbetinoFHClezardinPHow do bisphosphonates inhibit bone metastasis in vivo?Neoplasia201012757157820651986
  • DielIJJaschkeASolomayerEFAdjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow: a long-term follow-upAnn Oncol200819122007201118664560
  • ClezardinPEbetinoFHFournierPGBisphosphonates and cancer-induced bone disease: beyond their antiresorptive activityCancer Res200565124971497415958534
  • SolomayerEFGebauerGHirnlePInfluence of zoledronic acid on disseminated tumor cells in primary breast cancer patientsAnn Oncol Epub3 12012
  • RobertNJDierasVGlaspyJRIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancerJ Clin Oncol201129101252126021383283
  • MackeyJRKerbelRSGelmonKAControlling angiogenesis in breast cancer: A systematic review of anti-angiogenic trialsCancer Treat Rev201238667368822365657
  • SolomayerEFBeckerSPergola-BeckerGComparison of HER2 status between primary tumor and disseminated tumor cells in primary breast cancer patientsBreast Cancer Res Treat200698217918416552629
  • KrawczykNBanysMNeubauerHHER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumorAnticancer Res200929104019402419846945
  • FehmTHoffmannOAktasBDetection and characterization of circulating tumor cells in blood of primary breast cancer patients by RT-PCR and comparison to status of bone marrow disseminated cellsBreast Cancer Res2009114R5919664291
  • FehmTKrawczykNSolomayerEFERalpha-status of disseminated tumour cells in bone marrow of primary breast cancer patientsBreast Cancer Res2008105R7618793387
  • MengSTripathyDSheteSHER-2 gene amplification can be acquired as breast cancer progressesProc Natl Acad Sci U S A2004101259393939815194824
  • JückstockJRackBSchindlbeckCTreatment with trastuzumab in recurrence free patients with early breast cancer and persistent disseminated tumor cells (DTC) in bone marrowProceedings of the San Antonio Breast Cancer SymposiumDecember 10–14, 2008San Antonio (TX), USA
  • AktasBMullerVTewesMComparison of estrogen and progesterone receptor status of circulating tumor cells and the primary tumor in metastatic breast cancer patientsGynecol Oncol20111222356360 Epub May 24, 201121605893
  • RackBJuckstockJGunthner-BillerMTrastuzumab clears HER2/neu-positive isolated tumor cells from bone marrow in primary breast cancer patientsArch Gynecol Obstet20122852485492 Epub June 30, 201121717141
  • BozionellouVMavroudisDPerrakiMTrastuzumab administration can effectively target chemotherapy-resistant cytokeratin-19 messenger RNA-positive tumor cells in the peripheral blood and bone marrow of patients with breast cancerClin Cancer Res200410248185819415623593
  • CuriglianoGSpitaleriGPietriEBreast cancer vaccines: a clinical reality or fairy tale?Ann Oncol200617575076216293674
  • SchlomJTherapeutic cancer vaccines: current status and moving forwardJ Natl Cancer Inst2012104859961322395641
  • SemenzaGLTargeting HIF-1 for cancer therapyNat Rev Cancer200331072173213130303
  • WoelfeUCloosJSauterGMolecular signature associated with bone marrow micrometastasis in human breast cancerCancer Res200363185679568414522883
  • WeaverVMPetersenOWWangFReversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodiesJ Cell Biol199713712312459105051
  • Aguirre-GhisoJAEstradaYLiuDOssowskiLERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK)Cancer Res20036371684169512670923
  • RanganathanACZhangLAdamAPAguirre-GhisoJAFunctional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cellsCancer Res20066631702171116452230
  • MatsuzawaATakedaYNaritaMOzawaHSurvival of leukemic cells in a dormant state following cyclophosphamide-induced cure of strongly immunogenic mouse leukemia (DL811)Int J Cancer19914923033091879974
  • RabinovskyRUhrJWVitettaESYefenofECancer dormancy: lessons from a B cell lymphoma and adenocarcinoma of the prostateAdv Cancer Res20079718920217419946
  • QuintanaEShackletonMSabelMSFullenDRJohnsonTMMorrisonSJEfficient tumour formation by single human melanoma cellsNature2008456722259359819052619
  • NashKTPhadkePANavenotJMRequirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancyJ Natl Cancer Inst200799430932117312308
  • HorakCELeeJHMarshallJCShreeveSMSteegPSThe role of metastasis suppressor genes in metastatic dormancyAPMIS20081167–858660118834404
  • BarkanDGreenJEChambersAFExtracellular matrix: a gatekeeper in the transition from dormancy to metastatic growthEur J Cancer20104671181118820304630
  • EylesJPuauxALWangXTumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanomaJ Clin Invest201012062030203920501944