196
Views
0
CrossRef citations to date
0
Altmetric
Original Research

Effect of Heparinoid Moisturizer on Quality of Life in Patients with Acute Radiation Skin Damage Following Hypofractionated Radiation Therapy After Breast-Conserving Surgery: A Randomized Controlled Study

ORCID Icon, , , , & ORCID Icon
Pages 743-753 | Published online: 31 Dec 2021

References

  • McQuestionM. Evidence-based skin care management in radiation therapy: clinical update. Semin Oncol Nurs. 2011;27(2):e1–17. doi:10.1016/j.soncn.2011.02.009
  • BeamerLC, GrantM. Longitudinal trends in skin-related and global quality of life among women with breast radiodermatitis: a pilot study. Eur J Oncol Nurs. 2018;33:22–27. doi:10.1016/j.ejon.2018.01.00829551173
  • WongRK, BensadounRJ, Boers-DoetsCB, et al. Clinical practice guidelines for the prevention and treatment of acute and late radiation reactions from the MASCC Skin Toxicity Study Group. Support Care Cancer. 2013;21(10):2933–2948. doi:10.1007/s00520-013-1896-223942595
  • SekiguchiK, AkahaneK, OgitaM, et al. Efficacy of heparinoid moisturizer as a prophylactic agent for radiation dermatitis following radiotherapy after breast-conserving surgery: a randomized controlled trial. Jpn J Clin Oncol. 2018;48(5):450–457. doi:10.1093/jjco/hyy04529635534
  • SekiguchiK, OgitaM, AkahaneK, et al. Randomized, prospective assessment of moisturizer efficacy for the treatment of radiation dermatitis following radiotherapy after breast-conserving surgery. Jpn J Clin Oncol. 2015;45(12):1146–1153. doi:10.1093/jjco/hyv15526491204
  • OgitaM, SekiguchiK, AkahaneK, et al. Damage to sebaceous gland and the efficacy of moisturizer after whole breast radiotherapy: a randomized controlled trial. BMC Cancer. 2019;19(1):125. doi:10.1186/s12885-019-5334-930732579
  • YeeC, WangK, AsthanaR, et al. Radiation-induced skin toxicity in breast cancer patients: a systematic review of randomized trials. Clin Breast Cancer. 2018;18(5):e825–e840. doi:10.1016/j.clbc.2018.06.01530072193
  • FinlayAY, KhanGK. Dermatology Life Quality Index (DLQI)–a simple practical measure for routine clinical use. Clin Exp Dermatol. 1994;19(3):210–216. doi:10.1111/j.1365-2230.1994.tb01167.x8033378
  • BeamerLC, GrantM. Using the dermatology life quality index to assess how breast radiodermatitis affects patients’ quality of life. Breast Cancer (Auckl). 2019;13:1178223419835547. doi:10.1177/117822341983554731019366
  • HindleyA, ZainZ, WoodL, et al. Mometasone furoate cream reduces acute radiation dermatitis in patients receiving breast radiation therapy: results of a randomized trial. Int J Radiat Oncol Biol Phys. 2014;90(4):748–755. doi:10.1016/j.ijrobp.2014.06.03325585779
  • FukushimaS, KawamoriJ, HagaC, YamauchiH, SekiguchiKEffect of radiation dermatitis on quality of life in patients following radiation therapy after breast-conserving surgery: prospective observational study. Paper presented at: Proceedings of the 25th Annual Meeting of the the Japanese Breast Cancer Society (in Japanese); 2017; Fukuoka.
  • LongCC, FinlayAY. The finger-tip unit–a new practical measure. Clin Exp Dermatol. 1991;16(6):444–447. doi:10.1111/j.1365-2230.1991.tb01232.x1806320
  • National Cancer Institute, editor. Common Terminology Criteria for Adverse Events V4.03 (CTCAE). Bethesda, MD: National Institutes of Health; 2010.
  • MeghrajaniCF, CoHS, ArcillasJG, MaanoCC, CupinoNA. A randomized, double-blind trial on the use of 1% hydrocortisone cream for the prevention of acute radiation dermatitis. Expert Rev Clin Pharmacol. 2016;9(3):483–491. doi:10.1586/17512433.2016.112650626619355
  • WellsM, MacmillanM, RaabG, et al. Does aqueous or sucralfate cream affect the severity of erythematous radiation skin reactions? A randomised controlled trial. Radiother Oncol. 2004;73(2):153–162. doi:10.1016/j.radonc.2004.07.03215542162
  • PignolJP, OlivottoI, RakovitchE, et al. A multicenter randomized trial of breast intensity-modulated radiation therapy to reduce acute radiation dermatitis. J Clin Oncol. 2008;26(13):2085–2092. doi:10.1200/JCO.2007.15.248818285602
  • KeenanLG, LavanN, DunneM, McArdleO. Modifiable risk factors for acute skin toxicity in adjuvant breast radiotherapy: dosimetric analysis and review of the literature. Med Dosim. 2019;44(1):51–55. doi:10.1016/j.meddos.2018.01.00429576443
  • ShibaS, OkamotoM, KiyoharaH, et al. Clinical advantage of chest-wall post-mastectomy radiation therapy without Bolus. In Vivo (Brooklyn). 2018;32(4):961–965. doi:10.21873/invivo.11335
  • ArsenaultJ, ParpiaS, GoldbergM, et al. Acute toxicity and quality of life of hypofractionated radiation therapy for breast cancer. Int J Radiat Oncol Biol Phys. 2020;107(5):943–948. doi:10.1016/j.ijrobp.2020.03.04932334033
  • HickeyBE, JamesML, LehmanM, et al. Fraction size in radiation therapy for breast conservation in early breast cancer. Cochrane Database Syst Rev. 2016;7:CD003860. doi:10.1002/14651858.CD003860.pub427425588
  • ShaitelmanSF, SchlembachPJ, ArzuI, et al. Acute and short-term toxic effects of conventionally fractionated vs hypofractionated whole-breast irradiation: a randomized clinical trial. JAMA Oncol. 2015;1(7):931–941. doi:10.1001/jamaoncol.2015.266626247543
  • BronsardV, PaulC, PreyS, et al. What are the best outcome measures for assessing quality of life in plaque type psoriasis? A systematic review of the literature. J Eur Acad Dermatol Venereol. 2010;24(Suppl 2):17–22. doi:10.1111/j.1468-3083.2009.03563.x20443996
  • BasraMK, SalekMS, CamilleriL, SturkeyR, FinlayAY. Determining the minimal clinically important difference and responsiveness of the Dermatology Life Quality Index (DLQI): further data. Dermatology. 2015;230(1):27–33. doi:10.1159/00036539025613671
  • HarunaF, LipsettA, MarignolL. Topical management of acute radiation dermatitis in breast cancer patients: a systematic review and meta-analysis. Anticancer Res. 2017;37(10):5343–5353. doi:10.21873/anticanres.1196028982842
  • HoAY, Olm-ShipmanM, ZhangZ, et al. A randomized trial of mometasone furoate 0.1% to reduce high-grade acute radiation dermatitis in breast cancer patients receiving postmastectomy radiation. Int J Radiat Oncol Biol Phys. 2018;101(2):325–333. doi:10.1016/j.ijrobp.2018.02.00629726361
  • MillerRC, SchwartzDJ, SloanJA, et al. Mometasone furoate effect on acute skin toxicity in breast cancer patients receiving radiotherapy: a Phase III double-blind, randomized trial from the North Central Cancer Treatment Group N06C4. Int J Radiat Oncol Biol Phys. 2011;79(5):1460–1466. doi:10.1016/j.ijrobp.2010.01.03120800381
  • UlffE, MarotiM, SerupJ, FalkmerU. A potent steroid cream is superior to emollients in reducing acute radiation dermatitis in breast cancer patients treated with adjuvant radiotherapy. A randomised study of betamethasone versus two moisturizing creams. Radiother Oncol. 2013;108(2):287–292. doi:10.1016/j.radonc.2013.05.03323827771
  • UysalB, GamsızH, DincoglanF, et al. Comparative evaluation of topical corticosteroid and moisturizer in the prevention of radiodermatitis in breast cancer radiotherapy. Indian J Dermatol. 2020;65(4):279–283. doi:10.4103/ijd.IJD_607_1832831368
  • RollmannDC, NovotnyPJ, PetersenIA, et al. Double-blind, placebo-controlled pilot study of processed ultra emu oil versus placebo in the prevention of radiation dermatitis. Int J Radiat Oncol Biol Phys. 2015;92(3):650–658. doi:10.1016/j.ijrobp.2015.02.02825936812
  • ChitapanaruxI, TovanabutraN, ChiewchanvitS, et al. Emulsion of olive oil and calcium hydroxide for the prevention of radiation dermatitis in hypofractionation post-mastectomy radiotherapy: a randomized controlled trial. Breast Care (Basel). 2019;14(6):394–400. doi:10.1159/00049606231933586
  • RawlingsAV. Molecular basis for stratum corneum maturation and moisturization. Br J Dermatol. 2014;171(Suppl 3):19–28. doi:10.1111/bjd.1330325234174
  • LeeJ, ParkW, ChoiDH, et al. Patient-reported symptoms of radiation dermatitis during breast cancer radiotherapy: a pilot study. Qual Life Res. 2017;26(7):1713–1719. doi:10.1007/s11136-017-1526-428238091
  • BC Cancer Agency. Symptom management guidelines: radiation dermatitis; 2018. Available from:http://www.bccancer.bc.ca/nursing-site/Documents/16.%20Radiation%20Dermatitis.pdf. Accessed November8, 2016.
  • BolderstonA, LloydNS, WongRK, HoldenL, Robb-BlendermanL. The prevention and management of acute skin reactions related to radiation therapy: a systematic review and practice guideline. Support Care Cancer. 2006;14(8):802–817. doi:10.1007/s00520-006-0063-416758176
  • D’HaeseS, Van RoyM, BateT, BijdekerkeP, Vinh-HungV. Management of skin reactions during radiotherapy in Flanders (Belgium): a study of nursing practice before and after the introduction of a skin care protocol. Eur J Oncol Nurs. 2010;14(5):367–372. doi:10.1016/j.ejon.2009.10.00619944645
  • NystedtKE, HillJE, MitchellAM, et al. The standardization of radiation skin care in British Columbia: a collaborative approach. Oncol Nurs Forum. 2005;32(6):1199–1205. doi:10.1188/05.ONF.1199-120516270115
  • Japanese Society for Radiation Oncology, editor. Radiotherapy Q & A for Patients and Family, 2015 Edition. Tokyo: Kanehara-shuppan; 2015. (in Japanese).
  • BaumannBC, VerginadisII, ZengC, et al. Assessing the validity of clinician advice that patients avoid use of topical agents before daily radiotherapy treatments. JAMA Oncol. 2018;4(12):1742–1748. doi:10.1001/jamaoncol.2018.429230347008
  • IyamaA, MatsuyamaT, MatsumotoE, et al. Effect of metal-containing topical agents on surface doses received during external irradiation. J Radiat Res. 2018;59(6):794–799. doi:10.1093/jrr/rry07830247674
  • DalencF, RibetV, RossiAB, et al. Efficacy of a global supportive skin care programme with hydrotherapy after non-metastatic breast cancer treatment: a randomised, controlled study. Eur J Cancer Care (Engl). 2018;27(1):e12735. doi:10.1111/ecc.12735
  • LeonardiMC, GariboldiS, IvaldiGB, et al. A double-blind, randomised, vehicle-controlled clinical study to evaluate the efficacy of MAS065D in limiting the effects of radiation on the skin: interim analysis. Eur J Dermatol. 2008;18(3):317–321. doi:10.1684/ejd.2008.039618474463