Critical analysis of the potential for microRNA biomarkers in breast cancer management

References

• PratAPerouCMDeconstructing the molecular portraits of breast cancerMol Oncol20115152321147047
   PubMed Web of Science ®Google Scholar
• TofighASudermanMPaquetERThe prognostic ease and difficulty of invasive breast carcinomaCell Rep20149112914225284793
   PubMed Web of Science ®Google Scholar
• FoulkesWDSmithIEReis-FilhoJSTriple-negative breast cancerN Engl J Med2010363201938194821067385
   PubMed Web of Science ®Google Scholar
• DentRTrudeauMPritchardKITriple-negative breast cancer: clinical features and patterns of recurrenceClin Cancer Res20071315 Pt 14429443417671126
   PubMed Web of Science ®Google Scholar
• Di LevaGGarofaloMCroceCMMicroRNAs in cancerAnnu Rev Pathol2014928731424079833
   PubMed Web of Science ®Google Scholar
• HausserJZavolanMIdentification and consequences of miRNA-target interactions – beyond repression of gene expressionNat Rev Genet201415959961225022902
   PubMed Web of Science ®Google Scholar
• MachielaEPSempereLFIndividual noncoding RNA variations: their role in shaping and maintaining the epigenetic landscapeTollefsbolTPersonalized EpigeneticsElsevierin press
   Google Scholar
• KitaYVincentKNatsugoeSBerindan-NeagoeICalinGAEpigenetically regulated microRNAs and their prospect in cancer diagnosisExpert Rev Mol Diagn201414667368324914586
   PubMed Web of Science ®Google Scholar
• SempereLFFreemantleSPitha-RoweIMossEDmitrovskyEAmbrosVExpression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiationGenome Biol200453R1315003116
   PubMed Web of Science ®Google Scholar
• TranNHutvagnerGBiogenesis and the regulation of the maturation of miRNAsEssays Biochem201354172823829524
   PubMed Web of Science ®Google Scholar
• KozomaraAGriffiths-JonesSmiRBase: annotating high confidence microRNAs using deep sequencing dataNucleic Acids Res201442Database issueD68D7324275495
   PubMed Web of Science ®Google Scholar
• De CeccoLDugoMCanevariSDaidoneMGCallariMMeasuring microRNA expression levels in oncology: from samples to data analysisCrit Rev Oncog201318427328723614615
   PubMedGoogle Scholar
• ZhangXLuXLopez-BeresteinGSoodACalinGIn situ hybridization-based detection of microRNAs in human diseasesmicroRNA Diagn Ther2013111223
   Google Scholar
• de Planell-SaguerMRodicioMCDetection methods for microRNAs in clinic practiceClin Biochem20134610–1186987823499588
   PubMed Web of Science ®Google Scholar
• PritchardCCChengHHTewariMMicroRNA profiling: approaches and considerationsNat Rev Genet201213535836922510765
   PubMed Web of Science ®Google Scholar
• HowladerNNKrapchoMGarshellJSEER Cancer Statistics Review, 1975–2011National Cancer Institute2014 Available from: http://seer.cancer.gov/csr/1975_2011/Accessed October 31, 2014
   Google Scholar
• Kilburn-ToppinFBarterSJNew horizons in breast imagingClin Oncol (R Coll Radiol)20132529310023207071
   PubMed Web of Science ®Google Scholar
• KerlikowskeKZhuWHubbardRABreast Cancer Surveillance ConsortiumOutcomes of screening mammography by frequency, breast density, and postmenopausal hormone therapyJAMA Intern Med2013173980781623552817
   PubMed Web of Science ®Google Scholar
• BoydNFGuoHMartinLJMammographic density and the risk and detection of breast cancerN Engl J Med2007356322723617229950
   PubMed Web of Science ®Google Scholar
• De AbreuFBWellsWATsongalisGJThe emerging role of the molecular diagnostics laboratory in breast cancer personalized medicineAm J Pathol201318341075108323920325
   PubMed Web of Science ®Google Scholar
• TaylorDDGercel-TaylorCThe origin, function, and diagnostic potential of RNA within extracellular vesicles present in human biological fluidsFront Genet2013414223908664
   PubMedGoogle Scholar
• HaizhongMLiangCWangGMicroRNA-mediated cancer metastasis regulation via heterotypic signals in the microenvironmentCurr Pharm Biotechnol201415545545824846069
   PubMed Web of Science ®Google Scholar
• JarryJSchadendorfDGreenwoodCSpatzAvan KempenLCThe validity of circulating microRNAs in oncology: five years of challenges and contradictionsMol Oncol20148481982924656978
   PubMed Web of Science ®Google Scholar
• DobbinKKStatistical design and evaluation of biomarker studiesMethods Mol Biol2014110266767724259005
   PubMedGoogle Scholar
• WangKYuanYChoJHMcClartySBaxterDGalasDJComparing the MicroRNA spectrum between serum and plasmaPLoS One201277e4156122859996
   PubMed Web of Science ®Google Scholar
• LeidnerRSLiLThompsonCLDampening enthusiasm for circulating microRNA in breast cancerPLoS One201383e5784123472110
   PubMed Web of Science ®Google Scholar
• ShenJHuQSchrauderMCirculating miR-148b and miR-133a as biomarkers for breast cancer detectionOncotarget20145145284529425051376
   PubMedGoogle Scholar
• KodahlARZeuthenPBinderHKnoopASDitzelHJAlterations in circulating miRNA levels following early-stage estrogen receptor-positive breast cancer resection in post-menopausal womenPLoS One201497e10195025004125
   PubMed Web of Science ®Google Scholar
• SochorMBasovaPPestaMOncogenic microRNAs: miR-155, miR-19a, miR-181b, and miR-24 enable monitoring of early breast cancer in serumBMC Cancer20141444824938880
   PubMed Web of Science ®Google Scholar
• BrunoAELiLKalabusJLPanYYuAHuZmiRdSNP: a database of disease-associated SNPs and microRNA target sites on 3′UTRs of human genesBMC Genomics2012134422276777
   PubMed Web of Science ®Google Scholar
• MaXPZhangTPengBYuLJiang deKAssociation between microRNA polymorphisms and cancer risk based on the findings of 66 case-control studiesPLoS One2013811e7958424278149
   PubMed Web of Science ®Google Scholar
• XuYGuLPanYDifferent effects of three polymorphisms in MicroRNAs on cancer risk in Asian population: evidence from published literaturesPLoS One201386e6512323750236
   PubMed Web of Science ®Google Scholar
• YaoSGrahamKShenJGenetic variants in microRNAs and breast cancer risk in African American and European American womenBreast Cancer Res Treat2013141344745924062209
   PubMed Web of Science ®Google Scholar
• YangRSchleheBHemminkiKA genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer riskBreast Cancer Res Treat2010121369370219921425
   PubMed Web of Science ®Google Scholar
• ZhangNHuoQWangXA genetic variant in pre-miR-27a is associated with a reduced breast cancer risk in younger Chinese populationGene2013529112513023954879
   PubMed Web of Science ®Google Scholar
• HuZLiangJWangZCommon genetic variants in pre-microRNAs were associated with increased risk of breast cancer in Chinese womenHum Mutat2009301798418634034
   PubMed Web of Science ®Google Scholar
• CatucciIYangRVerderioPEvaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer casesHum Mutat2010311E1052E105719847796
   PubMed Web of Science ®Google Scholar
• ChenJQinZJiangYGenetic variations in the flanking regions of miR-101-2 are associated with increased risk of breast cancerPLoS One201491e8631924475105
   PubMed Web of Science ®Google Scholar
• ParanjapeTHeneghanHLindnerRA 3′-untranslated region KRAS variant and triple-negative breast cancer: a case-control and genetic analysisLancet Oncol201112437738621435948
   PubMed Web of Science ®Google Scholar
• HollestelleAPelletierCHooningMPrevalence of the variant allele rs61764370 T>G in the 3′UTR of KRAS among Dutch BRCA1, BRCA2 and non-BRCA1/BRCA2 breast cancer familiesBreast Cancer Res Treat20111281798420676756
   PubMed Web of Science ®Google Scholar
• CerneJZStegelVGersakKNovakovicSKRAS rs61764370 is associated with HER2-overexpressed and poorly-differentiated breast cancer in hormone replacement therapy users: a case control studyBMC Cancer20121210522436609
   PubMed Web of Science ®Google Scholar
• JiangYQinZHuZGenetic variation in a hsa-let-7 binding site in RAD52 is associated with breast cancer susceptibilityCarcinogenesis201334368969323188672
   PubMed Web of Science ®Google Scholar
• SaetromPBiesingerJLiSMA risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesisCancer Res200969187459746519738052
   PubMed Web of Science ®Google Scholar
• BaumgartenSCFrasorJMinireview: Inflammation: an instigator of more aggressive estrogen receptor (ER) positive breast cancersMol Endocrinol201226336037122301780
   PubMedGoogle Scholar
• WolffACHammondMESchwartzJNAmerican Society of Clinical OncologyCollege of American PathologistsAmerican Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancerJ Clin Oncol200725111814517159189
   PubMed Web of Science ®Google Scholar
• PaikSKimCWolmarkNHER2 status and benefit from adjuvant trastuzumab in breast cancerN Engl J Med2008358131409141118367751
   PubMed Web of Science ®Google Scholar
• VogelCLCobleighMATripathyDEfficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancerJ Clin Oncol200220371972611821453
   PubMed Web of Science ®Google Scholar
• SlamonDJLeyland-JonesBShakSUse of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2N Engl J Med20013441178379211248153
   PubMed Web of Science ®Google Scholar
• CobleighMAVogelCLTripathyDMultinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic diseaseJ Clin Oncol19991792639264810561337
   PubMed Web of Science ®Google Scholar
• ZhouJTengRWangQEndocrine resistance in breast cancer: current status and a perspective on the roles of miRNAs (Review)Oncol Lett20136229530524137320
   PubMed Web of Science ®Google Scholar
• WangSELinRJMicroRNA and HER2-overexpressing CancerMicrorna20132213714725070783
   PubMedGoogle Scholar
• YoshimotoNToyamaTTakahashiSDistinct expressions of microRNAs that directly target estrogen receptor alpha in human breast cancerBreast Cancer Res Treat2011130133133921755340
   PubMed Web of Science ®Google Scholar
• RaoXDi LevaGLiMMicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathwaysOncogene20113091082109721057537
   PubMed Web of Science ®Google Scholar
• GanRYangYYangXZhaoLLuJMengQHDownregulation of miR-221/222 enhances sensitivity of breast cancer cells to tamoxifen through upregulation of TIMP3Cancer Gene Ther201421729029624924200
   PubMed Web of Science ®Google Scholar
• XiongJYuDWeiNAn estrogen receptor alpha suppressor, microRNA-22, is downregulated in estrogen receptor alpha-positive human breast cancer cell lines and clinical samplesFEBS J201027771684169420180843
   PubMed Web of Science ®Google Scholar
• LoweryAJMillerNDevaneyAMicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancerBreast Cancer Res2009113R2719432961
   PubMed Web of Science ®Google Scholar
• CittellyDMDasPMSpoelstraNSDownregulation of miR-342 is associated with tamoxifen resistant breast tumorsMol Cancer2010931721172025
   PubMed Web of Science ®Google Scholar
• Di LevaGPiovanCGaspariniPEstrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor statusPLoS Genet201393e100331123505378
   PubMed Web of Science ®Google Scholar
• HeYJWuJZJiMHmiR-342 is associated with estrogen receptor-alpha expression and response to tamoxifen in breast cancerExp Ther Med20135381381823408138
   PubMed Web of Science ®Google Scholar
• HoppeRAchinger-KaweckaJWinterSIncreased expression of miR-126 and miR-10a predict prolonged relapse-free time of primary oestrogen receptor-positive breast cancer following tamoxifen treatmentEur J Cancer201349173598360823968733
   PubMed Web of Science ®Google Scholar
• Rodríguez-GonzálezFGSieuwertsAMSmidMMicroRNA-30c expression level is an independent predictor of clinical benefit of endocrine therapy in advanced estrogen receptor positive breast cancerBreast Cancer Res Treat20111271435120490652
   PubMed Web of Science ®Google Scholar
• RotheFIgnatiadisMChaboteauxCGlobal microRNA expression profiling identifies MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancerPLoS One201166e2098021738599
   PubMed Web of Science ®Google Scholar
• WardAShuklaKBalwierzAMicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancerJ Pathol2014233436837924752803
   PubMed Web of Science ®Google Scholar
• LyngMBLaenkholmAVSokildeRGravgaardKHLitmanTDitzelHJGlobal microRNA expression profiling of high-risk ER+ breast cancers from patients receiving adjuvant tamoxifen mono-therapy: a DBCG studyPLoS One201275e3617022623953
   PubMed Web of Science ®Google Scholar
• FoekensJASieuwertsAMSmidMFour miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor- positive human breast cancerProc Natl Acad Sci U S A200810535130211302618755890
   PubMed Web of Science ®Google Scholar
• ToyamaTKondoNEndoYHigh expression of microRNA-210 is an independent factor indicating a poor prognosis in Japanese triple-negative breast cancer patientsJpn J Clin Oncol201242425626322323552
   PubMed Web of Science ®Google Scholar
• BuffaFMCampsCWinchesterLmicroRNA associated progression pathways and potential therapeutic targets identified by integrated mRNA and microRNA expression profiling in breast cancerCancer Res201171175635564521737487
   PubMed Web of Science ®Google Scholar
• HongLYangJHanYLuQCaoJSyedLHigh expression of miR-210 predicts poor survival in patients with breast cancer: a meta-analysisGene2012507213513822842193
   PubMed Web of Science ®Google Scholar
• CampsCBuffaFMColellaShsa-miR-210 Is induced by hypoxia and is an independent prognostic factor in breast cancerClin Cancer Res20081451340134818316553
   PubMed Web of Science ®Google Scholar
• CampsCSainiHKMoleDRIntegrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxiaMol Cancer2014132824517586
   PubMed Web of Science ®Google Scholar
• ScottGKGogaABhaumikDBergerCESullivanCSBenzCCCoordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125bJ Biol Chem200728221479148617110380
   PubMed Web of Science ®Google Scholar
• LeivonenSKSahlbergKKMäkeläRHigh-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growthMol Oncol2014819310424148764
   PubMed Web of Science ®Google Scholar
• FangCZhaoYGuoBMiR-199b-5p targets HER2 in breast cancer cellsJ Cell Biochem201311471457146323296799
   PubMed Web of Science ®Google Scholar
• IorioMVCasaliniPPiovanCmicroRNA-205 regulates HER3 in human breast cancerCancer Res20096962195220019276373
   PubMed Web of Science ®Google Scholar
• IchikawaTSatoFTerasawaKTrastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cellsPLoS One201272e3142222384020
   PubMed Web of Science ®Google Scholar
• LeXFAlmeidaMIMaoWModulation of MicroRNA-194 and cell migration by HER2-targeting trastuzumab in breast cancerPLoS One201277e4117022829924
   PubMed Web of Science ®Google Scholar
• LeeJALeeHYLeeESKimIBaeJWPrognostic Implications of MicroRNA-21 Overexpression in Invasive Ductal Carcinomas of the BreastJ Breast Cancer201114426927522323912
   PubMed Web of Science ®Google Scholar
• PerssonHKvistARegoNIdentification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 geneCancer Res2011711788621199797
   PubMed Web of Science ®Google Scholar
• GongCYaoYWangYUp-regulation of miR-21 mediates resistance to trastuzumab therapy for breast cancerJ Biol Chem201128621191271913721471222
   PubMed Web of Science ®Google Scholar
• YeXBaiWZhuHMiR-221 promotes trastuzumab-resistance and metastasis in HER2-positive breast cancers by targeting PTENBMB Rep201447526827324286315
   PubMed Web of Science ®Google Scholar
• FalkenbergNAnastasovNRapplKMiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasionBr J Cancer2013109102714272324129242
   PubMed Web of Science ®Google Scholar
• MattieMDBenzCCBowersJOptimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsiesMol Cancer200652416784538
   PubMed Web of Science ®Google Scholar
• GaoLBBaiPPanXMThe association between two polymorphisms in pre-miRNAs and breast cancer risk: a meta-analysisBreast Cancer Res Treat2011125257157420640596
   PubMed Web of Science ®Google Scholar
• GaspariniPCascioneLFassanMmicroRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancersOncotarget2014551174118424632568
   PubMedGoogle Scholar
• KolacinskaAMorawiecJPawlowskaZAssociation of microRNA-93, 190, 200b and receptor status in core biopsies from stage III breast cancer patientsDNA Cell Biol201433962462924865188
   PubMed Web of Science ®Google Scholar
• OuyangMLiYYeSMicroRNA profiling implies new markers of chemoresistance of triple-negative breast cancerPLoS One201495e9622824788655
   PubMed Web of Science ®Google Scholar
• SempereLFChristensenMSilahtarogluAAltered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancerCancer Res20076724116121162018089790
   PubMed Web of Science ®Google Scholar
• SempereLFPreisMYezefskiTFluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MicroRNA expression in solid tumorsClin Cancer Res201016164246425520682703
   PubMed Web of Science ®Google Scholar
• PreisMGardnerTBGordonSRmicroRNA-10b expression correlates with response to neoadjuvant therapy and survival in pancreatic ductal adenocarcinomaClin Cancer Res201117175812582121652542
   PubMed Web of Science ®Google Scholar
• JørgensenSBakerAMollerSNielsenBSRobust one-day in situ hybridization protocol for detection of microRNAs in paraffin samples using LNA probesMethods201052437538120621190
   PubMed Web of Science ®Google Scholar
• RaskLBalslevEJørgensenSHigh expression of miR-21 in tumor stroma correlates with increased cancer cell proliferation in human breast cancerAPMIS20111191066367321917003
   PubMed Web of Science ®Google Scholar
• SusmanSTomuleasaCFeketeZPilatoBIrimieABerindan-NeagoeIThe importance of microRNAs in the stroma-breast cancer cell interplayCancer Biomark2014142–313714424878814
   PubMed Web of Science ®Google Scholar
• SempereLFTissue slide-based microRNA characterization of tumors: how detailed could diagnosis become for cancer medicine?Expert Rev Mol Diagn201414785386925090088
   PubMed Web of Science ®Google Scholar
• GongCNieYQuSmiR-21 induces myofibroblast differentiation and promotes the malignant progression of breast phyllodes tumorsCancer Res201474164341435224980553
   PubMed Web of Science ®Google Scholar
• BullockMDPickardKMNielsenBSPleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progressionCell Death Dis20134e68423788041
   PubMed Web of Science ®Google Scholar
• KaderaBELiLTostePAMicroRNA-21 in pancreatic ductal adenocarcinoma tumor-associated fibroblasts promotes metastasisPLoS One201388e7197823991015
   PubMed Web of Science ®Google Scholar
• MackenzieTASchwartzGCalderoneHMStromal expression of miR-21 identifies high-risk group in triple-negative breast cancerAm J Pathol2014184123217322525440114
   PubMed Web of Science ®Google Scholar
• WangLWangJMicroRNA-mediated breast cancer metastasis: from primary site to distant organsOncogene201231202499251121963843
   PubMed Web of Science ®Google Scholar
• MaLReinhardtFPanETherapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor modelNat Biotechnol201028434134720351690
   PubMed Web of Science ®Google Scholar
• MaLTeruya-FeldsteinJWeinbergRATumour invasion and metastasis initiated by microRNA-10b in breast cancerNature2007449716368268817898713
   PubMed Web of Science ®Google Scholar
• AhmadASethiSChenWAli-FehmiRMittalSSarkarFHUp- regulation of microRNA-10b is associated with the development of breast cancer brain metastasisAm J Transl Res20146438439025075255
   PubMed Web of Science ®Google Scholar
• ParrellaPBarbanoRPasculliBEvaluation of microRNA-10b prognostic significance in a prospective cohort of breast cancer patientsMol Cancer20141314224897960
   PubMed Web of Science ®Google Scholar
• ChenWCaiFZhangBBarekatiZZhongXYThe level of circulating miRNA-10b and miRNA-373 in detecting lymph node metastasis of breast cancer: potential biomarkersTumour Biol201334145546223238818
   PubMedGoogle Scholar
• ZhaoFLHuGDWangXFZhangXHZhangYKYuZSSerum overexpression of microRNA-10b in patients with bone metastatic primary breast cancerJ Int Med Res201240385986622906258
   PubMed Web of Science ®Google Scholar
• AnfossiSGiordanoAGaoHHigh serum miR-19a levels are associated with inflammatory breast cancer and are predictive of favorable clinical outcome in patients with metastatic HER2+ inflammatory breast cancerPLoS One201491e8311324416156
   PubMed Web of Science ®Google Scholar
• MarkouAYousefGMStathopoulosEGeorgouliasVLianidouEPrognostic significance of metastasis-related microRNAs in early breast cancer patients with a long follow-upClin Chem201460119720524132943
   PubMed Web of Science ®Google Scholar
• GeeHECampsCBuffaFMMicroRNA-10b and breast cancer metastasisNature20084557216E8E9 ; author reply E918948893
   PubMed Web of Science ®Google Scholar
• GravgaardKHLyngMBLaenkholmAVThe miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancerBreast Cancer Res Treat2012134120721722294488
   PubMed Web of Science ®Google Scholar
• RyuSMcDonnellKChoiHSuppression of miRNA-708 by polycomb group promotes metastases by calcium-induced cell migrationCancer Cell2013231637623328481
   PubMed Web of Science ®Google Scholar
• OkudaHXingFPandeyPRmiR-7 suppresses brain metastasis of breast cancer stem-like cells by modulating KLF4Cancer Res20137341434144423384942
   PubMed Web of Science ®Google Scholar
• KrutilinaRSunWSethuramanAMicroRNA-18a inhibits hypoxia-inducible factor 1-alpha activity and lung metastasis in basal breast cancersBreast Cancer Res2014164R7825069832
   PubMed Web of Science ®Google Scholar
• ChouJLinJHBrenotAKimJWProvotSWerbZGATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expressionNat Cell Biol201315220121323354167
   PubMed Web of Science ®Google Scholar
• PellegrinoLStebbingJBragaVMmiR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcriptsNucleic Acids Res201341105400541223580553
   PubMed Web of Science ®Google Scholar
• EllBQiuQWeiYThe MicroRNA-23b/27b/24 cluster promotes breast cancer lung metastasis by targeting metastasis- suppressive gene prosaposinJ Biol Chem201428932218882189524966325
   PubMed Web of Science ®Google Scholar
• MostertBSieuwertsAMMartensJWSleijferSDiagnostic applications of cell-free and circulating tumor cell-associated miRNAs in cancer patientsExpert Rev Mol Diagn201111325927521463236
   PubMed Web of Science ®Google Scholar
• SieuwertsAMMostertBBolt-de VriesJmRNA and microRNA expression profiles in circulating tumor cells and primary tumors of metastatic breast cancer patientsClin Cancer Res201117113600361821505063
   PubMed Web of Science ®Google Scholar
• MadhavanDZucknickMWallwienerMCirculating miRNAs as surrogate markers for circulating tumor cells and prognostic markers in metastatic breast cancerClin Cancer Res201218215972598222952344
   PubMed Web of Science ®Google Scholar
• LiQLiuMMaFCirculating miR-19a and miR-205 in serum may predict the sensitivity of luminal A subtype of breast cancer patients to neoadjuvant chemotherapy with epirubicin plus paclitaxelPLoS One201498e10487025137071
   PubMed Web of Science ®Google Scholar
• JungEJSantarpiaLKimJPlasma microRNA 210 levels correlate with sensitivity to trastuzumab and tumor presence in breast cancer patientsCancer2012118102603261422370716
   PubMed Web of Science ®Google Scholar
• MullerVGadeSSteinbachBChanges in serum levels of miR-21, miR-210, and miR-373 in HER2-positive breast cancer patients undergoing neoadjuvant therapy: a translational research project within the Geparquinto trialBreast Cancer Res Treat20141471616825086636
   PubMed Web of Science ®Google Scholar
• Asuragen [webpage on the Internet]miRInform^® PancreasAustin, TXAsuragen, Inc2014 Available from: http://asuragen.com/products-and-services/clinical-lab/mirinform-pancreas/Accessed October 31, 2014
   Google Scholar
• Rosetta Genomics [webpage on the Internet]MicroRNAs in DiagnosticsPhiladelphia, PARosetta Genomics Inc Available from: http://www.rosettagenomics.com/micrornas-in-diagnosticsAccessed October 31, 2014
   Google Scholar
• FinakGBertosNPepinFStromal gene expression predicts clinical outcome in breast cancerNat Med200814551852718438415
   PubMed Web of Science ®Google Scholar
• KristensenVNVaskeCJUrsini-SiegelJIntegrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signalingProc Natl Acad Sci U S A201210982802280721908711
   PubMed Web of Science ®Google Scholar
• JoosseSAMullerVSteinbachBPantelKSchwarzenbachHCirculating cell-free cancer-testis MAGE-A RNA, BORIS RNA, let-7b and miR-202 in the blood of patients with breast cancer and benign breast diseasesBr J Cancer2014111590991724983365
   PubMed Web of Science ®Google Scholar
• ChanMLiawCSJiSMIdentification of circulating microRNA signatures for breast cancer detectionClin Cancer Res201319164477448723797906
   PubMed Web of Science ®Google Scholar
• Mar-AguilarFMendoza-RamirezJAMalagón-SantiagoISerum circulating microRNA profiling for identification of potential breast cancer biomarkersDis Markers201334316316923334650
   PubMed Web of Science ®Google Scholar
• KodahlARLyngMBBinderHNovel circulating microRNA signature as a potential non-invasive multi-marker test in ER-positive early-stage breast cancer: a case control studyMol Oncol20148587488324694649
   PubMed Web of Science ®Google Scholar
• GuoLZhaoYYangSCaiMWuQChenFGenome-wide screen for aberrantly expressed miRNAs reveals miRNA profile signature in breast cancerMol Biol Rep20134032175218623196705
   PubMed Web of Science ®Google Scholar
• GodfreyACXuZWeinbergCRSerum microRNA expression as an early marker for breast cancer risk in prospectively collected samples from the Sister Study cohortBreast Cancer Res2013153R4223705859
   PubMed Web of Science ®Google Scholar
• GaoJZhangQXuJGuoLLiXClinical significance of serum miR-21 in breast cancer compared with CA153 and CEAChin J Cancer Res201325674374824385703
   PubMed Web of Science ®Google Scholar
• SiHSunXChenYCirculating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancerJ Cancer Res Clin Oncol2013139222322923052693
   PubMed Web of Science ®Google Scholar
• LuoJZhaoQZhangWA novel panel of microRNAs provides a sensitive and specific tool for the diagnosis of breast cancerMol Med Rep201410278579124866395
   PubMed Web of Science ®Google Scholar
• ZengRCZhangWYanXQDown-regulation of miRNA-30a in human plasma is a novel marker for breast cancerMed Oncol201330147723389917
   PubMed Web of Science ®Google Scholar
• CukKZucknickMMadhavanDPlasma microRNA panel for minimally invasive detection of breast cancerPLoS One2013810e7672924194846
   PubMed Web of Science ®Google Scholar
• WatersPSDwyerRMBroughamCImpact of tumour epithelial subtype on circulating microRNAs in breast cancer patientsPLoS One201493e9060524626163
   PubMed Web of Science ®Google Scholar
• CukKZucknickMHeilJCirculating microRNAs in plasma as early detection markers for breast cancerInt J Cancer201313271602161222927033
   PubMed Web of Science ®Google Scholar
• LiuJMaoQLiuYHaoXZhangSZhangJAnalysis of miR-205 and miR-155 expression in the blood of breast cancer patientsChin J Cancer Res2013251465423372341
   PubMed Web of Science ®Google Scholar
• WangPYGongHTLiBFHigher expression of circulating miR-182 as a novel biomarker for breast cancerOncol Lett2013661681168624260062
   PubMed Web of Science ®Google Scholar
• ZearoSKimEZhuYMicroRNA-484 is more highly expressed in serum of early breast cancer patients compared to healthy volunteersBMC Cancer20141420024641801
   PubMed Web of Science ®Google Scholar
• ChenQHWangQBZhangBEthnicity modifies the association between functional microRNA polymorphisms and breast cancer risk: a HuGE meta-analysisTumour Biol201435152954323982873
   PubMedGoogle Scholar
• KontorovichTLevyAKorostishevskyMNirUFriedmanESingle nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk womenInt J Cancer2010127358959719950226
   PubMed Web of Science ®Google Scholar
• ZhongSChenZXuJLiWZhaoJPre-mir-27a rs895819 polymorphism and cancer risk: a meta-analysisMol Biol Rep20134043181318623266669
   PubMed Web of Science ®Google Scholar
• XuQHeCYLiuJWYuanYPre-miR-27a rs895819A/G polymorphisms in cancer: a meta-analysisPLoS One201386e6520823762318
   PubMed Web of Science ®Google Scholar
• BensenJTTseCKNyanteSJBarnholtz-SloanJSColeSRMillikanRCAssociation of germline microRNA SNPs in pre-miRNA flanking region and breast cancer risk and survival: the Carolina Breast Cancer StudyCancer Causes Control20132461099110923526039
   PubMed Web of Science ®Google Scholar
• PastrelloCPoleselJDella PuppaLVielAMaestroRAssociation between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patientsCarcinogenesis201031122124212620810544
   PubMed Web of Science ®Google Scholar
• WangPYGaoZHJiangZHLiXXJiangBFXieSYThe associations of single nucleotide polymorphisms in miR-146a, miR-196a and miR-499 with breast cancer susceptibilityPLoS One201389e7065624039706
   PubMed Web of Science ®Google Scholar
• LeeSJSeoJWChaeYSGenetic polymorphism of miR-196a as a prognostic biomarker for early breast cancerAnticancer Res20143462943294924922658
   PubMed Web of Science ®Google Scholar
• LinharesJJAzevedoMJrSiufiAAEvaluation of single nucleotide polymorphisms in microRNAs (hsa-miR-196a2 rs11614913 C/T) from Brazilian women with breast cancerBMC Med Genet20121311923228090
   PubMed Web of Science ®Google Scholar
• SmithRAJedlinskiDJGabrovskaPNWeinsteinSRHauptLGriffithsLRA genetic variant located in miR-423 is associated with reduced breast cancer riskCancer Genomics Proteomics20129311511822593246
   PubMed Web of Science ®Google Scholar
• ChenPZhangJZhouFmiR-499 rs3746444 polymorphism is associated with cancer development among Asians and related to breast cancer susceptibilityMol Biol Rep20123912104331043823053947
   PubMed Web of Science ®Google Scholar
• SunHLiQYangTWangWQuantitative assessment of the association between microRNA-499 rs3746444 A/G polymorphism and cancer riskTumour Biol20143532351235824258110
   PubMedGoogle Scholar
• FanCChenCWuDThe association between common genetic variant of microRNA-499 and cancer susceptibility: a meta-analysisMol Biol Rep20134043389339423271127
   PubMed Web of Science ®Google Scholar
• NicolosoMSSunHSpizzoRSingle-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibilityCancer Res20107072789279820332227
   PubMed Web of Science ®Google Scholar
• HeNZhengHLiPmiR-485-5p binding site SNP rs8752 in HPGD gene is associated with breast cancer riskPLoS One201497e10209325003827
   PubMed Web of Science ®Google Scholar
• GilamAEdryLMamluk-MoragEInvolvement of IGF-1R regulation by miR-515-5p modifies breast cancer risk among BRCA1 carriersBreast Cancer Res Treat2013138375376023549953
   PubMed Web of Science ®Google Scholar
• WangLLiuWJiangWA miRNA binding site single-nucleotide polymorphism in the 3′-UTR region of the IL23R gene is associated with breast cancerPLoS One2012712e4982323239971
   PubMed Web of Science ®Google Scholar
• ZhengJJiangLZhangLFunctional genetic variations in the IL-23 receptor gene are associated with risk of breast, lung and nasopharyngeal cancer in Chinese populationsCarcinogenesis201233122409241623042301
   PubMed Web of Science ®Google Scholar
• ZhengHSongFZhangLGenetic variants at the miR-124 binding site on the cytoskeleton-organizing IQGAP1 gene confer differential predisposition to breast cancerInt J Oncol20113841153116121318219
   PubMed Web of Science ®Google Scholar
• BrendleALeiHBrandtAPolymorphisms in predicted microRNA-binding sites in integrin genes and breast cancer: ITGB4 as prognostic markerCarcinogenesis20082971394139918550570
   PubMed Web of Science ®Google Scholar
• ZhangLLiuYSongFFunctional SNP in the microRNA-367 binding site in the 3′UTR of the calcium channel ryanodine receptor gene 3 (RYR3) affects breast cancer risk and calcificationProc Natl Acad Sci U S A201110833136531365821810988
   PubMed Web of Science ®Google Scholar
• ZhangBLSongFJZhengHZhangLNZhaoYRChenKXSNP rs16917496 within SET8 3′UTR is associated with the age of onset of breast cancerZhonghua Zhong Liu Za Zhi20123411835837 Chinese23291132
   PubMedGoogle Scholar
• QuesneJLJonesJWarrenJBiological and prognostic associations of miR-205 and let-7b in breast cancer revealed by in situ hybridization analysis of micro-RNA expression in arrays of archival tumour tissueJ Pathol2012227330631422294324
   PubMed Web of Science ®Google Scholar
• RadojicicJZaravinosAVrekoussisTKafousiMSpandidosDAStathopoulosENMicroRNA expression analysis in triple-negative (ER, PR and Her2/neu) breast cancerCell Cycle201110350751721270527
   PubMed Web of Science ®Google Scholar
• CascioneLGaspariniPLovatFIntegrated microRNA and mRNA signatures associated with survival in triple negative breast cancerPLoS One201382e5591023405235
   PubMed Web of Science ®Google Scholar
• DongGLiangXWangDHigh expression of miR-21 in triple-negative breast cancers was correlated with a poor prognosis and promoted tumor cell in vitro proliferationMed Oncol20143175724930006
   PubMed Web of Science ®Google Scholar
• SvobodaMSanaJRedovaMMiR-34b is associated with clinical outcome in triple-negative breast cancer patientsDiagn Pathol201273122439831
   PubMed Web of Science ®Google Scholar
• BerberUYilmazINarliGHaholuAKucukodaciZDemirelDmiR-205 and miR-200c: predictive micro RNAs for lymph node metastasis in triple negative breast cancerJ Breast Cancer201417214314825013435
   PubMed Web of Science ®Google Scholar
• de RinaldisEGazinskaPMeraAIntegrated genomic analysis of triple-negative breast cancers reveals novel microRNAs associated with clinical and molecular phenotypes and sheds light on the pathways they controlBMC Genomics20131464324059244
   PubMed Web of Science ®Google Scholar
• EichelserCFlesch-JanysDChang-ClaudeJPantelKSchwarzenbachHDeregulated serum concentrations of circulating cell-free microRNAs miR-17, miR-34a, miR-155, and miR-373 in human breast cancer development and progressionClin Chem201359101489149623748853
   PubMed Web of Science ®Google Scholar
• TangDZhangQZhaoSThe expression and clinical significance of microRNA-1258 and heparanase in human breast cancerClin Biochem20134610–1192693223415719
   PubMed Web of Science ®Google Scholar