Breast cancer causes and treatment: where are we going wrong?

References

• MukhtarTKYeatesDRGoldacreMJBreast cancer mortality trends in England and the assessment of the effectiveness of mammography screening: population-based studyJ R Soc Med201310623424223761583
   PubMed Web of Science ®Google Scholar
• ForouzanfarMHForemanKJDelossantosAMBreast and cervical cancer in 187 countries between 1980 and 2010: a systematic analysisLancet20113781461148421924486
   PubMed Web of Science ®Google Scholar
• AutierPBoniolMGavinAVattenLJBreast cancer mortality in neighbouring European countries with different levels of screening but similar access to treatment: trend analysis of WHO mortality databaseBMJ2011343d441121798968
   PubMed Web of Science ®Google Scholar
• GinsbergOLoveRRBreast cancer: a neglected disease for the majority of affected women worldwideBreast J20111728929521410589
   PubMed Web of Science ®Google Scholar
• BrennanSFCantwellMMCardwellCRVelentzisLSWoodsideJVDietary patterns and breast cancer risk: a systematic review and meta-analysisAm J Clin Nutr2010911294130220219961
   PubMed Web of Science ®Google Scholar
• ThomsonCAThompsonPADietary patterns, risk and prognosis of breast cancerFuture Oncol200951257126919852740
   PubMed Web of Science ®Google Scholar
• LofMWeiderpassEImpact of diet on breast cancer riskCurr Opin Obstet Gynecol200921808519125007
   PubMed Web of Science ®Google Scholar
• GaudetMMGapsturSMSunJDiverWRHannanLMThunMJActive smoking and breast cancer risk: original cohort data and meta-analysisJ Natl Cancer Inst201310551552523449445
   PubMed Web of Science ®Google Scholar
• LuoJMargolisKLWactawski-WendeJAssociation of active and passive smoking with risk of breast cancer among postmenopausal women: a prospective cohort studyBMJ2011342d101621363864
   PubMed Web of Science ®Google Scholar
• JohnsonKCMillerABCollishawNEActive smoking and secondhand smoke increase breast cancer risk: the report of the Canadian Expert Panel on Tobacco Smoke and Breast Cancer Risk (2009)Tob Control201120e221148114
   PubMed Web of Science ®Google Scholar
• PijpeAAndrieuNEastonDFExposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK)BMJ2012345e566022956590
   PubMed Web of Science ®Google Scholar
• RonckersCMErdmannCALandCERadiation and breast cancer: a review of current evidenceBreast Cancer Res20057213215642178
   PubMed Web of Science ®Google Scholar
• MettlerFAMedical effects and risks of exposure to ionizing radiationJ Radiol Prot201232N9N1322395124
   PubMed Web of Science ®Google Scholar
• JoshiDBuehringGCAre viruses associated with human breast cancer? Scrutinizing the molecular evidenceBreast Cancer Res Treat201213511522274134
   PubMed Web of Science ®Google Scholar
• SimõesPWMedeirosLRSimões PiresPDPrevalence of human papillomavirus in breast cancer: a systematic reviewInt J Gynecol Cancer20122234334722214962
   PubMed Web of Science ®Google Scholar
• [No authors listed]The 2007 recommendations of the International Commission on Radiological Protection: ICRP publication 103Ann ICRP2007371332
   Google Scholar
• BoydMAA regulatory perspective on whether the system of radiation protection is fit for purposeAnn ICRP201241576323089004
   PubMedGoogle Scholar
• PentreathRJEthics, genetics and dynamics: an emerging systematic approach to radiation protection of the environmentJ Environ Radioact200474193015063533
   PubMed Web of Science ®Google Scholar
• Tria TironaMBreast cancer screening updateAm Fam Physician20138727427823418799
   PubMed Web of Science ®Google Scholar
• SchopperDde WolfCHow effective are breast cancer screening programmes by mammography? Review of the current evidenceEur J Cancer2009451916192319398327
   PubMed Web of Science ®Google Scholar
• de KoningHJMammographic screening: evidence from randomised controlled trialsAnn Oncol2003141185118912881373
   PubMed Web of Science ®Google Scholar
• BeemsterboerPMWarmerdamPGBoerRde KoningHJRadiation risk of mammography related to benefit in screening programmes: a favourable balance?J Med Screen1998581879718526
   PubMed Web of Science ®Google Scholar
• DrukteinisJSMooneyBPFlowersCIGatenbyRABeyond mammography: new frontiers in breast cancer screeningAm J Med201312647247923561631
   PubMed Web of Science ®Google Scholar
• QuanstrumKHHaywardRALessons from the mammography warsN Engl J Med20103631076107920825322
   PubMed Web of Science ®Google Scholar
• BrennerDJSlowing the increase in the population dose resulting from CT scansRadiat Res201017480981520731591
   PubMed Web of Science ®Google Scholar
• MaloneJGuleriaRCravenCJustification of diagnostic medical exposures: some practical issues. Report of an International Atomic Energy Agency ConsultationBr J Radiol20128552353821343316
   PubMed Web of Science ®Google Scholar
• BakerSRBhattiWAThe thyroid cancer epidemic: is it the dark side of the CT revolution?Eur J Radiol200660676916787731
   PubMed Web of Science ®Google Scholar
• KrilleLZeebHJahnenAComputed tomographies and cancer risk in children: a literature overview of CT practices, risk estimations and an epidemiologic cohort study proposalRadiat Environ Biophys20125110311122310909
   PubMed Web of Science ®Google Scholar
• HallEJBrennerDJCancer risks from diagnostic radiology: the impact of new epidemiological dataBr J Radiol201285e1316e131723175496
   PubMed Web of Science ®Google Scholar
• BrennerDJMinimising medically unwarranted computed tomography scansAnn ICRP20124116116923089015
   PubMedGoogle Scholar
• BrennerDJHallEJCancer risks from CT scans: now we have data, what next?Radiology201226533033122915598
   PubMed Web of Science ®Google Scholar
• IannacconePMWeinbergWCDeamantFDOn the clonal origin of tumors: a review of experimental modelsInt J Cancer1987397787843294611
   PubMed Web of Science ®Google Scholar
• FucicABrunborgGLasanRJezekDKnudsenLEMerloDFGenomic damage in children accidentally exposed to ionizing radiation: a review of the literatureMutat Res200865811112318155954
   PubMed Web of Science ®Google Scholar
• NordlingCOA new theory on the cancer-inducing mechanismBr J Cancer19537687213051507
   PubMed Web of Science ®Google Scholar
• MarjanovicNDWeinbergRAChafferCLCell plasticity and heterogeneity in cancerClin Chem20135916817923220226
   PubMed Web of Science ®Google Scholar
• WeinbergRAMechanisms of malignant progressionCarcinogenesis2008291092109518453542
   PubMed Web of Science ®Google Scholar
• KnudsonAGJrMutation and cancer: statistical study of retinoblastomaProc Natl Acad Sci U S A1971688208235279523
   PubMed Web of Science ®Google Scholar
• MothersillCSeymourCChanging paradigms in radiobiologyMutat Res2012750859522273762
   PubMed Web of Science ®Google Scholar
• Barcellos-HoffMHNew biological insights on the link between radiation exposure and breast cancer riskJ Mammary Gland Biol Neoplasia20131831323325014
   PubMed Web of Science ®Google Scholar
• Barcellos-HoffMHLydenDWangTCThe evolution of the cancer niche during multistage carcinogenesisNat Rev Cancer20131351151823760023
   PubMed Web of Science ®Google Scholar
• MothersillCSeymourCBRadiation-induced bystander effects – implications for cancerNat Rev Cancer2004415816414964312
   PubMed Web of Science ®Google Scholar
• HaldaneJBSScience and Everyday Life1st edNew York, NYMacMillan1940
   Google Scholar
• HymanLHThe Invertebrates: Protozoa through Ctenophora1st edNew York, NYMcGraw Hill1940
   Google Scholar
• WehlandMBauerJInfangerMGrimmDTarget-based anti-angiogenic therapy in breast cancerCurr Pharm Des2012184244425722632607
   PubMed Web of Science ®Google Scholar
• RussellJSBrownJMThe irradiated tumor microenvironment: role of tumor-associated macrophages in vascular recoveryFront Physiol2013415716323882218
   PubMed Web of Science ®Google Scholar
• KozinSVDudaDGMunnLLJainRKIs vasculogenesis crucial for the regrowth of irradiated tumours?Nat Rev Cancer20111153253721701514
   PubMed Web of Science ®Google Scholar
• ChenFHChiangCSWangCCVasculatures in tumors growing from preirradiated tissues: formed by vasculogenesis and resistant to radiation and antiangiogenic therapyInt J Radiat Oncol Biol Phys2011801512152121621344
   PubMed Web of Science ®Google Scholar
• BrownMHenry S Kaplan Distinguished Scientist Award Lecture 2007. The remarkable yin and yang of tumour hypoxiaInt J Radiat Biol20108690791720569190
   PubMed Web of Science ®Google Scholar
• SpadaroMAmbrosinoEIezziMCure of mammary carcinomas in Her-2 transgenic mice through sequential stimulation of innate (neoadjuvant interleukin-12) and adaptive (DNA vaccine electroporation) immunityClin Cancer Res2005111941195215756020
   PubMed Web of Science ®Google Scholar
• SaijoNProgress in cancer chemotherapy with special stress on molecular-targeted therapyJpn J Clin Oncol20104085586220651047
   PubMed Web of Science ®Google Scholar
• StopeckATBrown-GlabermanUWongHYThe role of targeted therapy and biomarkers in breast cancer treatmentClin Exp Metastasis20122980781922692561
   PubMed Web of Science ®Google Scholar
• GuerinEManSXuPKerbelRSA model of postsurgical advanced metastatic breast cancer more accurately replicates the clinical efficacy of antiangiogenic drugsCancer Res2013732743274823610448
   PubMed Web of Science ®Google Scholar
• Le BourhisXRomonRHondermarckHRole of endothelial progenitor cells in breast cancer angiogenesis: from fundamental research to clinical ramificationsBreast Cancer Res Treat2010120172420033768
   PubMed Web of Science ®Google Scholar
• MareelMConstantinoSEcosystems of invasion and metastasis in mammary morphogenesis and cancerInt J Dev Biol20115567168422161824
   PubMed Web of Science ®Google Scholar
• PagetSThe distribution of secondary growths in cancer of the breastLancet1989898101
   Google Scholar
• FidlerIJPosteGThe “seed and soil” hypothesis revisitedLancet Oncol20089980818672217
   PubMed Web of Science ®Google Scholar
• FidlerIJYanoSZhangRFujimakiTBucanaCDThe seed and soil hypothesis: vascularisation and brain metastasesLancet Oncol20023535711905606
   PubMed Web of Science ®Google Scholar
• NobleDModeling the heart – from genes to cells to the whole organScience20022951678168211872832
   PubMed Web of Science ®Google Scholar
• LoebLASpringgateCFBattulaNErrors in DNA replication as a basis of malignant changesCancer Res197434231123214136142
   PubMed Web of Science ®Google Scholar
• LoebLACancer cells exhibit a mutator phenotypeAdv Cancer Res19987225569338073
   PubMed Web of Science ®Google Scholar
• FoxEJLoebLALethal mutagenesis: targeting the mutator phenotype in cancerSemin Cancer Biol20102035335920934515
   PubMed Web of Science ®Google Scholar
• KooninEVWolfYIEvolution of microbes and viruses: a paradigm shift in evolutionary biology?Front Cell Infect Microbiol2012211912522993722
   PubMed Web of Science ®Google Scholar
• FonvilleNCWardRMMittelmanDStress-induced modulators of repeat instability and genome evolutionJ Mol Microbiol Biotechnol201121364422248541
   PubMed Web of Science ®Google Scholar
• GalhardoRSHastingsPJRosenbergSMMutation as a stress response and the regulation of evolvabilityCrit Rev Biochem Mol Biol20074239943517917874
   PubMed Web of Science ®Google Scholar
• BlissMWilliam Osler: A Life in MedicineToronto, ONUniversity of Ontario Press1999
   Google Scholar
• SridharanSDal PraACattonCBristowRGWardePLocally advanced prostate cancer: current controversies and optimisation opportunitiesClin Oncol (R Coll Radiol)20122549950523680106
   PubMed Web of Science ®Google Scholar
• BristowRGHillRPHypoxia and metabolism. Hypoxia, DNA repair and genetic instabilityNat Rev Cancer2008818019218273037
   PubMed Web of Science ®Google Scholar
• FoxEJPrindleMJLoebLADo mutator mutations fuel tumorigenesis?Cancer Metastasis Rev Epub4 172013
   Web of Science ®Google Scholar
• OslerWChauvanism in MedicineThe Montreal Medical Journal1902XXXI
   Google Scholar
• SwinfordS15,000 people die every year because of cancer treatments, Lord Saatchi saysThe Telegraph5 202013 Available from: http://www.telegraph.co.uk/health/10069585/15000-people-die-every-year-because-of-cancer-treatments-Lord-Saatchi-says.htmlAccessed October 30, 2013
   Google Scholar
• PaulosJAMammogram MathThe New York Times12 102009 Available from: http://www.nytimes.com/2009/12/13/magazine/13Fob-wwln-t.html?_r=0Accessed October 2, 2013
   Google Scholar
• Editorial. The Controversy over MammogramsThe New York Times12 202009 Available from: http://health.nytimes.com/health/guides/test/mammography/news-and-features.html?page=3Accessed October 2, 2013
   Google Scholar
• NadellCDBucciVDrescherKLevinSABasslerBLXavierJBCutting through the complexity of cell collectivesProc Biol Sci20132802012277023363630
   PubMed Web of Science ®Google Scholar
• ThattaiMUsing topology to tame the complex biochemistry of genetic networksPhilos Trans A Math Phys Eng Sci20123712011054823277605
   PubMed Web of Science ®Google Scholar
• NaviauxRKMetabolic features of the cell danger responseMitochondrion Epub8 242013
   Web of Science ®Google Scholar
• CalabreseEJHormesis: improving predictions in the low-dose zoneEXS201210155156422945582
   PubMedGoogle Scholar
• RussoJRussoIHBreast development, hormones and cancerAdv Exp Med Biol2008630525618637484
   PubMed Web of Science ®Google Scholar
• RussoJRussoIHThe role of the basal stem cell of the human breast in normal development and cancerAdv Exp Med Biol201172012113421901623
   PubMed Web of Science ®Google Scholar
• WilsonEOConsilience, The Unity of KnowledgeNew York, NYVintage Books1999
   Google Scholar
• Definition of Science Available from: http://en.wikipedia.org/wiki/Science10 22013
   Google Scholar
• KuhnTThe Structure of Scientific Revolutions3rd edChicago, ILUniversity of Chicago2012
   Google Scholar
• VogelsteinBPapadopoulosNVelculescuVEZhouSDiazLAJrKinzlerKWCancer genome landscapesScience20133391546155823539594
   PubMed Web of Science ®Google Scholar
• Paracelsus Available from: http://en.wikipedia.org/wiki/ParacelsusAccessed October 2, 2013
   Google Scholar
• Paracelsus and homoeopathy Available from: http://www.similima.com/paracelsus-and-homoeopathyAccessed October 2, 2013
   Google Scholar
• MullerHJThe measurement of gene mutation rate in drosophila, its high variability, and its dependence upon temperatureGenetics19281327935717246553
   PubMedGoogle Scholar
• CarlsonEAGenes, Radiation, and Society: the Life and Work of H J MullerIthaca, NYCornell University Press1981
   Google Scholar
• CalabreseEJMuller’s Nobel lecture on dose-response for ionizing radiation: ideology or science?Arch Toxicol2011851495149821717110
   PubMed Web of Science ®Google Scholar