Hidradenitis suppurativa: from pathogenesis to diagnosis and treatment

References

• KurzenHKurokawaIJemecGBWhat causes hidradenitis suppurativa?Exp Dermatol20081745547218400064
   PubMed Web of Science ®Google Scholar
• NaldiLEpidemiologyJemecGRevuzJLeydenJJHidradenitis SuppurativeBerlinSpringer20065864
   Google Scholar
• AlikhanALynchPJEisenDBHidradenitis suppurativa: a comprehensive reviewJ Am Acad Dermatol200960453956119293006
   PubMed Web of Science ®Google Scholar
• RevuzJECanoui-PoitrineFWolkensteinPPrevalence and factors associated with hidradenitis suppurativa: results from two case-control studiesJ Am Acad Dermatol20085959660118674845
   PubMed Web of Science ®Google Scholar
• JemecGBHeidenheimMNielsenNHThe prevalence of hidradenitis suppurativa and its potential precursor lesionsJ Am Acad Dermatol1996351911948708018
   PubMed Web of Science ®Google Scholar
• JemecGBThe symptomatology of hidradenitis suppurativa in womenBr J Dermatol19881193453503179207
   PubMed Web of Science ®Google Scholar
• VazquezBGAlikhanAWeaverALWetterDADavisMDIncidence of hidradenitis suppurativa and associated factors: a population-based study of Olmsted County, MinnesotaJ Invest Dermatol20131339710322931916
   PubMed Web of Science ®Google Scholar
• CosmatosIMatchoAWeinsteinRMontgomeryMOStangPAnalysis of patient claims data to determine the prevalence of hidradenitis suppurativa in the United StatesJ Am Acad Dermatol20136841241922921795
   PubMed Web of Science ®Google Scholar
• MargessonLJDanbyFWHidradenitis suppurativaBest Pract Res Clin Obstet Gynaecol2014281013102725214437
   PubMed Web of Science ®Google Scholar
• EsmannSDufourDNJemecGBQuestionnaire-based diagnosis of hidradenitis suppurativa: specificity, sensitivity and positive predictive value of specific diagnostic questionsBr J Dermatol201016310210620331444
   PubMed Web of Science ®Google Scholar
• ZouboulisCCDesaiNEmtestamLEuropean S1 guideline for the treatment of hidradenitis suppurativa/acne inversaJ Eur Acad Dermatol Venereol20152961964425640693
   PubMed Web of Science ®Google Scholar
• de WinterKvan der ZeeHHPrensEPIs mechanical stress an important pathogenic factor in hidradenitis suppurativa?Exp Dermatol20122117617722379963
   PubMed Web of Science ®Google Scholar
• SchraderAMDeckersIEvan der ZeeHHBoerJPrensEPHidradenitis suppurativa: a retrospective study of 846 Dutch patients to identify factors associated with disease severityJ Am Acad Dermatol20147146046724880664
   PubMed Web of Science ®Google Scholar
• FitzsimmonsJSGuilbertPRA family study of hidradenitis suppurativaJ Med Genet1985223673732934550
   PubMed Web of Science ®Google Scholar
• PinkAESimpsonMADesaiNMutations in the gamma-secretase genes NCSTN, PSENEN, and PSEN1 underlie rare forms of hidradenitis suppurativa (acne inversa)J Invest Dermatol20121322459246122622421
   PubMed Web of Science ®Google Scholar
• WangBYangWWenWGamma-secretase gene mutations in familial acne inversaScience2010330106520929727
   PubMed Web of Science ®Google Scholar
• PinkAESimpsonMADesaiNTrembathRCBarkerJNGamma-secretase mutations in hidradenitis suppurativa: new insights into disease pathogenesisJ Invest Dermatol201313360160723096707
   PubMed Web of Science ®Google Scholar
• ScheinfeldNHidradenitis suppurativa: a practical review of possible medical treatments based on over 350 hidradenitis patientsDermatol Online J2013191
   PubMedGoogle Scholar
• PrensEDeckersIPathophysiology of hidradenitis suppurativa: an updateJ Am Acad Dermatol2015735 Suppl 1S8S1126470623
   PubMed Web of Science ®Google Scholar
• JemecGBThomsenBMHansenUThe homogeneity of hidradenitis suppurativa lesions. A histological study of intra-individual variationAPMIS19971053783839201239
   PubMed Web of Science ®Google Scholar
• JemecGBHansenUHistology of hidradenitis suppurativaJ Am Acad Dermatol1996349949998647993
   PubMed Web of Science ®Google Scholar
• von LaffertMHelmboldPWohlrabJFiedlerEStadieVMarschWCHidradenitis suppurativa (acne inversa): early inflammatory events at terminal follicles and at interfollicular epidermisExp Dermatol20101953353719659829
   PubMed Web of Science ®Google Scholar
• BoerJWeltevredenEFHidradenitis suppurativa or acne inversa. A clinicopathological study of early lesionsBr J Dermatol19961357275
   Web of Science ®Google Scholar
• KampSFiehnAMStenderupKHidradenitis suppurativa: a disease of the absent sebaceous gland? Sebaceous gland number and volume are significantly reduced in uninvolved hair follicles from patients with hidradenitis suppurativaBr J Dermatol201116451017102221250966
   PubMed Web of Science ®Google Scholar
• KathjuSLaskoLAStoodleyPConsidering hidradenitis suppurativa as a bacterial biofilm diseaseFEMS Immunol Med Microbiol201265238538922353357
   PubMedGoogle Scholar
• Guet-RevilletHCoignard-BiehlerHJaisJPBacterial pathogens associated with hidradenitis suppurativa, FranceEmerg Infect Dis201420121990199825418454
   PubMed Web of Science ®Google Scholar
• MatusiakLBieniekASzepietowskiJCBacteriology of hidradenitis suppurativa – which antibiotics are the treatment of choice?Acta Derm Venereol201494669970224604152
   PubMed Web of Science ®Google Scholar
• HofmannSCSaborowskiVLangeSKernWVBruckner-TudermanLRiegSExpression of innate defense antimicrobial peptides in hidradenitis suppurativaJ Am Acad Dermatol20126696697421982063
   PubMed Web of Science ®Google Scholar
• EmelianovVUBecharaFGGläserRImmunohistological pointers to a possible role for excessive cathelicidin (LL-37) expression by apocrine sweat glands in the pathogenesis of hidradenitis suppurativa/acne inversaBr J Dermatol20121661023103422136668
   PubMed Web of Science ®Google Scholar
• BecharaFGSandMSkryganMKreuterAAltmeyerPGambichlerTAcne inversa: evaluating antimicrobial peptides and proteinsAnn Dermatol20122439339723197903
   PubMed Web of Science ®Google Scholar
• MammucariCTommasi di VignanoASharovAAIntegration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation controlDev Cell2005866567615866158
   PubMed Web of Science ®Google Scholar
• MelnikBCPlewigGImpaired Notch-MKP-1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biologyExp Dermatol20132217217723489419
   PubMed Web of Science ®Google Scholar
• RangarajanATaloraCOkuyamaRNotch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiationEMBO J2001203427343611432830
   PubMed Web of Science ®Google Scholar
• PanYLinMHTianXGamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesisDev Cell2004773174315525534
   PubMed Web of Science ®Google Scholar
• van der ZeeHHLamanJDde RuiterLDikWAPrensEPAdalimumab (antitumour necrosis factor-α) treatment of hidradenitis suppurativa ameliorates skin inflammation: an in situ and ex vivo studyBr J Dermatol201216629830522013960
   PubMed Web of Science ®Google Scholar
• HungerRESurovyAMHassanASBraathenLRYawalkarNToll-like receptor 2 is highly expressed in lesions of acne inversa and colocalizes with C-type lectin receptorBr J Dermatol200815869169718241264
   PubMed Web of Science ®Google Scholar
• ReFStromingerJLToll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cellsJ Biol Chem2001276376923769911477091
   PubMed Web of Science ®Google Scholar
• SchlapbachCHänniTYawalkarNHungerREExpression of the IL-23/Th17 pathway in lesions of hidradenitis suppurativaJ Am Acad Dermatol20116579079821641076
   PubMed Web of Science ®Google Scholar
• Giamarellos-BourboulisEJAntonopoulouAPetropoulouCAltered innate and adaptive immune responses in patients with hidrad-enitis suppurativaBr J Dermatol2007156515617199566
   PubMed Web of Science ®Google Scholar
• ZhangQWangCLiuZNotch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activationJ Biol Chem20122876208621722205705
   PubMed Web of Science ®Google Scholar
• MozeikaEPilmaneMNürnbergBMJemecGBTumour necrosis factor-alpha and matrix metalloproteinase-2 are expressed strongly in hidradenitis suppurativaActa Derm Venereol20139330130423096596
   PubMed Web of Science ®Google Scholar
• van der ZeeHHLamanJDBoerJPrensEPHidradenitis suppurativa: viewpoint on clinical phenotyping, pathogenesis and novel treatmentsExp Dermatol20122173573922882284
   PubMed Web of Science ®Google Scholar
• KathjuSLaskoLStoodleyPConsidering hidradenitis suppurativa as a bacterial biofilm diseaseFEMS Immunol Med Microbiol20126538538922353357
   PubMedGoogle Scholar
• JahnsACKillasliHNosekDMicrobiology of hidradenitis suppurativa (acne inversa): a histological study of 27 patientsAPMIS201412280480924475943
   PubMed Web of Science ®Google Scholar
• YuCCCookMGHidradenitis suppurativa: a disease of follicular epithelium, rather than apocrine glandsBr J Dermatol19901227637692369556
   PubMed Web of Science ®Google Scholar
• EsmannSJemecGBPsychosocial impact of hidradenitis suppurativa: a qualitative studyActa Derm Venereol20119132833221394419
   PubMed Web of Science ®Google Scholar
• BrownTJRosenTOrengoIFHidradenitis suppurativaSouth Med J199891110711149853721
   PubMed Web of Science ®Google Scholar
• SladeDEMPowellBWMortimerPSHidradenitis suppurativa: pathogenesis and managementBr J Plast Surg20035645146112890458
   PubMedGoogle Scholar
• ShalomGFreudTHarman-BoehmIPolishchukICohenADHidradenitis suppurativa and metabolic syndrome: a comparative cross-sectional study of 3207 patientsBr J Dermatol2015173246447025760289
   PubMed Web of Science ®Google Scholar
• RevuzJHidradenitis suppurativaJ Eur Acad Dermatol Venereol200923998599819682181
   PubMed Web of Science ®Google Scholar
• KimballABKerdelFAdamsDAdalimumab for the treatment of moderate to severe hidradenitis suppurativa: a parallel randomized trialAnn Intern Med201215784685523247938
   PubMed Web of Science ®Google Scholar
• SartoriusKKillasliHHeilbornJJemecGBLapinsJEmtestamLInterobserver variability of clinical scores in hidradenitis suppurativa is lowBr J Dermatol20101621261126820184581
   PubMed Web of Science ®Google Scholar
• AmanoMGrantAKerdelFAA prospective open-label clinical trial of adalimumab for the treatment of hidradenitis suppurativaInt J Dermatol20104995095521128923
   PubMed Web of Science ®Google Scholar
• JemecGBBiomarkers in hidradenitis suppurativaBr J Dermatol201316811511153
   Web of Science ®Google Scholar
• HurleyHJAxillary hyperhidrosis, apocrine bromhidrosis, hidradenitis suppurativa, and familial benign pemphigus: surgical approachRoenigkRKRoenigkHHDermatologic SurgeryNew YorkMarcel Dekker1996623645
   Google Scholar
• SartoriusKEmtestamLJemecGBLapinsJObjective scoring of hidradenitis suppurativa reflecting the role of tobacco smoking and obesityBr J Dermatol200916183183919438453
   PubMed Web of Science ®Google Scholar
• SartoriusKLapinsJEmtestamLJemecGBSuggestions for uniform outcome variables when reporting treatment effects in hidradenitis suppurativaBr J Dermatol200314921121312890229
   PubMed Web of Science ®Google Scholar
• GrantAGonzalezTMontgomeryMOCardenasVKerdelFAInfliximab therapy for patients with moderate to severe hidradenitis suppurativa: a randomized, double-blind, placebo-controlled crossover trialJ Am Acad Dermatol20106220521720115947
   PubMed Web of Science ®Google Scholar
• PascoeVLKimballABHidradenitis suppurativa: current progress and future questionsJAMA Dermatol20141501263126425229429
   PubMed Web of Science ®Google Scholar
• GoldDAReederVJMahanMGHamzaviIHThe prevalence of metabolic syndrome in patients with hidradenitis suppurativaJ Am Acad Dermatol20147069970324433875
   PubMed Web of Science ®Google Scholar
• ShlyankevichJChenAJKimGEKimballABHidradenitis suppurativa is a systemic disease with substantial comorbidity burden: a chart-verified case-control analysisJ Am Acad Dermatol20147161144115025440440
   PubMed Web of Science ®Google Scholar
• MillerIMEllervikCVindingGRAssociation of metabolic syndrome and hidradenitis suppurativaJAMA Dermatol20141501273128025229996
   PubMed Web of Science ®Google Scholar
• DeckersIEBenhadouFKoldijkMJInflammatory bowel disease is associated with hidradenitis suppurativa: results from a multicenter cross-sectional studyJ Am Acad Dermatol2017761495327793450
   PubMed Web of Science ®Google Scholar
• NapolitanoMMegnaMMonfrecolaGInsulin resistance and skin diseasesScientific World J20152015479354
   Google Scholar
• BettoliVNaldiLCazzanigaSOverweight, diabetes and disease duration influence clinical severity in hidradenitis suppurativa–acne inversa. Evidence from the national Italian registryBr J Dermatol2016174119519725913460
   PubMed Web of Science ®Google Scholar
• MonfrecolaGBalatoACaiazzoGMammalian target of rapamycin, insulin resistance and hidradenitis suppurativa: a possible metabolic loopJ Eur Acad Dermatol Venereol20163091631163326299257
   PubMed Web of Science ®Google Scholar
• TianGLiangJNWangZYZhouDEmerging role of leptin in rheumatoid arthritisClin Exp Immunol201417755757024802245
   PubMed Web of Science ®Google Scholar
• SabatRChanwangpongASchneider-BurrusSIncreased prevalence of metabolic syndrome in patients with acne inversaPLoS One20127e3181022359634
   PubMed Web of Science ®Google Scholar
• EgebergAGislasonGHHansenPRRisk of major adverse cardiovascular events and all-cause mortality in patients with hidradenitis suppurativaJAMA Dermatol2016152442943426885728
   PubMed Web of Science ®Google Scholar
• MillerIMMcAndrewRJHamzaviIPrevalence, risk factors, and comorbidities of hidradenitis suppurativaDermatol Clin201634171626617352
   PubMed Web of Science ®Google Scholar
• ShavitEDreiherJFreudTHalevySVinkerSCohenADPsychiatric comorbidities in 3207 patients with hidradenitis suppurativaJ Eur Acad Dermatol Venereol20152937137624909646
   PubMed Web of Science ®Google Scholar
• OnderdijkAJvan der ZeeHHEsmannSDepression in patients with hidradenitis suppurativaJ Eur Acad Dermatol Venereol201327447347822339940
   PubMed Web of Science ®Google Scholar
• YadavSSinghSEdakkanambeth VarayilJHidradenitis suppurativa in patients with inflammatory bowel disease: a population-based cohort study in Olmsted County, MinnesotaClin Gastroenterol Hepatol2016141657025952308
   PubMed Web of Science ®Google Scholar
• KamalNCohenBLBucheSDelaporteEColombelJFFeatures of patients with Crohn’s disease and hidradenitis suppurativaClin Gastroenterol Hepatol2016141717925956836
   PubMed Web of Science ®Google Scholar
• HsiaoJLAntayaRJBergerTMaurerTShinkaiKLeslieKSHidradenitis suppurativa and concomitant pyoderma gangrenosum: a case series and literature reviewArch Dermatol2010146111265127021079064
   PubMedGoogle Scholar
• RichettePMoltoAViguierMHidradenitis suppurativa associated with spondyloarthritis – results from a multicenter national prospective studyJ Rheumatol20144149049424429166
   PubMed Web of Science ®Google Scholar
• BhallaRSequeiraWArthritis associated with hidradenitis suppurativaAnn Rheum Dis19945364668311560
   PubMed Web of Science ®Google Scholar
• VasanthVChandrashekarBSFollicular occlusion tetradIndian Dermatol Online J2014549149325396138
   PubMedGoogle Scholar
• ConstantinouCWidomKDesantisJObmannMHidradenitis suppurativa complicated by squamous cell carcinomaAm Surg200874121177118119097532
   PubMed Web of Science ®Google Scholar
• ScheinfeldNA case of a patient with stage III familial hidradenitis suppurativa treated with 3 courses of infliximab and died of metastatic squamous cell carcinomaDermatol Online J2014203
   Google Scholar
• ClemmensenOJTopical treatment of hidradenitis suppurativa with clindamycinInt J Dermatol1983223253286347922
   PubMed Web of Science ®Google Scholar
• JemecGBEWendelboePTopical clindamycin versus systemic tetracycline in the treatment of hidradenitis suppurativaJ Am Acad Dermatol1998399719749843011
   PubMed Web of Science ®Google Scholar
• GenerGCanoui-PoitrineFRevuzJECombination therapy with clindamycin and rifampicin for hidradenitis suppurativa: a series of 116 consecutive patientsDermatology200921914815419590173
   PubMed Web of Science ®Google Scholar
• MendoncaCOGriffithsCEClindamycin and rifampicin combination therapy for hidradenitis suppurativaBr J Dermatol200615497797816634904
   PubMed Web of Science ®Google Scholar
• van der ZeeHHBoerJPrensEPJemevJBThe effect of combined treatment with oral clindamycin and oral rifampicin in patients with hidradenitis suppurativaDermatology200921914314719590174
   PubMed Web of Science ®Google Scholar
• BettoliVZauliSBorghiAOral clindamycin and rifampicin in the treatment of hidradenitis suppurativa–acne inversa: a prospective study on 23 patientsJ Eur Acad Dermatol Venereol20142812512623451831
   PubMed Web of Science ®Google Scholar
• DessiniotiCZisimouCTzanetakouVStratigosAAntoniouCOral clindamycin and rifampicin combination therapy for hidradenitis suppurativa: a prospective study and 1-year follow-upClin Exp Dermatol201641885285727753139
   PubMed Web of Science ®Google Scholar
• Join-LambertOCoignardHJaisJPEfficacy of rifampin–moxifloxacin–metronidazole combination therapy in hidradenitis suppurativaDermatology20112221495821109728
   PubMed Web of Science ®Google Scholar
• Join-LambertOCoignard-BiehlerHJaisJPEfficacy of ertapenem in severe hidradenitis suppurativa: a pilot study in a cohort of 30 consecutive patientsJ Antimicrob Chemother201671251352026565016
   PubMed Web of Science ®Google Scholar
• MeixnerDSchneiderSKrauseMSterryWAcne inversaJ Dtsch Dermatol Ges2008618919618093218
   PubMed Web of Science ®Google Scholar
• BoerJNazaryMLong-term results of acitretin therapy for hidradenitis suppurativa. Is acne inversa also a misnomer?Br J Dermatol201116417017520874789
   PubMed Web of Science ®Google Scholar
• MatusiakLBieniekASzepietowskiJCAcitretin in hidradenitis suppurativa treatment – own experiencesPrzegl Dermatol201299356357
   Google Scholar
• TanMGShearNHWalshSAlhusayenRAcitretin: monotherapy or combined therapy for hidradenitis suppurativa?J Cutan Med Surg2016211485327432818
   PubMed Web of Science ®Google Scholar
• ChowETMortimerPSSuccessful treatment of hidradenitis suppurativa and retroauricular acne with etretinateBr J Dermatol1992126415
   PubMed Web of Science ®Google Scholar
• HoganDJLightMJSuccessful treatment of hidradenitis suppurativa with acitretinJ Am Acad Dermatol1988193553562971689
   PubMed Web of Science ®Google Scholar
• SchemanAJNodulocystic acne and hidradenitis suppurativa treated with acitretin: a case reportCutis20026928728812080949
   PubMed Web of Science ®Google Scholar
• VahlquistAGriffithsWRetinoid therapy in hidradenitis suppurativa – a report of a caseRetinoids Today Tom1990182830
   Google Scholar
• GuptaAKEllisCNNickoloffBJOral cyclosporine in the treatment of inflammatory and noninflammatory dermatoses. A clinical and immunopathologic analysisArch Dermatol19901263393502178558
   PubMedGoogle Scholar
• RoseRFGoodfieldMJClarkSMTreatment of recalcitrant hidradenitis suppurativa with oral ciclosporinClin Exp Dermatol20063115415516309527
   PubMed Web of Science ®Google Scholar
• BuckleyDARogersSCyclosporin-responsive hidradenitis suppurativaJ R Soc Med199588289290
   PubMed Web of Science ®Google Scholar
• AndersonMDZauliSBettoliVBoerJJemecGBCyclosporine treatment of severe hidradenitis suppurativa – a case seriesJ Dermatolog Treat201627324725026406923
   PubMed Web of Science ®Google Scholar
• YazdanyarSBoerJIngvarssonGSzepietowskiJCJemecGBDapsone therapy for hidradenitis suppurativa: a series of 24 patientsDermatology201122234234621757878
   PubMed Web of Science ®Google Scholar
• KaurMRLewisHMHidradenitis suppurativa treated with dapsone: a case series of five patientsJ Dermatolog Treat20061721121316971313
   PubMed Web of Science ®Google Scholar
• HoferTItinPHAcne inversa: a dapsone-sensitive dermatosisHautarzt200152989992 German11715401
   PubMed Web of Science ®Google Scholar
• SoriaACanoui-PoitrineFWolkensteinPAbsence of efficacy of oral isotretinoin in hidradenitis suppurativa: a retrospective study based on patients’ outcome assessmentDermatology200921813413519060466
   PubMed Web of Science ®Google Scholar
• BoerJMirjanJPGemertVLong-term results of isotretinoin in the treatment of 68 patients with hidradenitis suppurativaJ Am Acad Dermatol19994073769922015
   PubMed Web of Science ®Google Scholar
• NorrisJFCunliffeWJFailure of treatment of familial widespread hidradenitis suppurativa with isotretinoinClin Exp Dermatol1986115795833478160
   PubMed Web of Science ®Google Scholar
• JemecGGEGniadeckaMSebum excretion in hidradenitis suppurativaDermatology19971943253289252751
   PubMed Web of Science ®Google Scholar
• HaslundPLeeRAJemecGBTreatment of hidradenitis suppurativa with tumour necrosis factor-alpha inhibitorsActa Derm Venereol20098959560019997689
   PubMed Web of Science ®Google Scholar
• MegnaMBettoliVChimentiSHidradenitis suppurativa: guidelines of the Italian Society of Dermatology and Venereology (SIDeMaST) for the use of anti-TNF-α agentsG Ital Dermatol Venereol2015150673173926513043
   PubMed Web of Science ®Google Scholar
• ShujaFChanCSRosenTBiologic drugs for the treatment of hidradenitis suppurativa: an evidence-based reviewDermatol Clin20102851152420510761
   PubMed Web of Science ®Google Scholar
• van RappardDCMooijJEBaetenDLMekkesJRNew-onset polyarthritis during successful treatment of hidradenitis suppurativa with infliximabBr J Dermatol201116519419821428974
   PubMed Web of Science ®Google Scholar
• BrunassoAMDelfinoCMassoneCHidradenitis suppurativa: are tumour necrosis factor-alpha blockers the ultimate alternative?Br J Dermatol200815976176318627370
   PubMed Web of Science ®Google Scholar
• DelageMSamimiMAtlanMMachetLLoretteGMaruaniAEfficacy of infliximab for hidradenitis suppurativa: assessment of clinical and biological inflammatory markersActa Derm Venereol20119116917121384087
   PubMed Web of Science ®Google Scholar
• FardetLDupuyAKerobDInfliximab for severe hidradenitis suppurativa: transient clinical efficacy in 7 consecutive patientsJ Am Acad Dermatol20075662462817240478
   PubMed Web of Science ®Google Scholar
• Fernandez-VozmedianoJMArmario-HitaJCInfliximab for the treatment of hidradenitis suppurativaDermatology2007215414417587838
   PubMed Web of Science ®Google Scholar
• LasockiASinclairRFoleyPSaundersHHidradenitis suppurativa responding to treatment with infliximabAustralas J Dermatol20105118619020695857
   PubMed Web of Science ®Google Scholar
• MekkesJRBosJDLong-term efficacy of a single course of infliximab in hidradenitis suppurativaBr J Dermatol200815837037418047504
   PubMed Web of Science ®Google Scholar
• ParadelaSRodriguez-LojoRFernandez-TorresRArévaloPFonsecaELong-term efficacy of infliximab in hidradenitis suppurativaJ Dermatolog Treat20122327828322482700
   PubMed Web of Science ®Google Scholar
• PedrazJDaudenEPerez-GalaSGoiriz-ValdésRFernández-PeñasPGarcía-DiezAHidradenitis suppurativa. Response to treatment with infliximabActas Dermosifiliogr200798325331 Spanish17555675
   PubMedGoogle Scholar
• UsmaniNClaytonTHEverettSGoodfieldMDVariable response of hidradenitis suppurativa to infliximab in four patientsClin Exp Dermatol20073220420517342798
   PubMed Web of Science ®Google Scholar
• ArenbergerovaMGkalpakiotisSArenbergerPEffective long-term control of refractory hidradenitis suppurativa with adalimumab after failure of conventional therapyInt J Dermatol2010491445144921091684
   PubMed Web of Science ®Google Scholar
• BlancoRMartinez-TaboadaVMVillaILong-term successful adalimumab therapy in severe hidradenitis suppurativaArch Dermatol200914558058419451504
   PubMed Web of Science ®Google Scholar
• SotiriouEApallaZVakirlisEIoannidesDEfficacy of adalimumab in recalcitrant hidradenitis suppurativaEur J Dermatol20091918018119153066
   PubMed Web of Science ®Google Scholar
• YamauchiPSMauNHidradenitis suppurativa managed with adalimumabJ Drugs Dermatol2009818118319213236
   PubMed Web of Science ®Google Scholar
• AbbVieA phase 3 multicenter study of the safety and efficacy of adalimumab in subjects with moderate to severe hidradenitis suppurativa – PIONEER I ClinicalTials.gov, Identifier: NCT01468207 [last updated October 15, 2015]. Available from: https://clinicaltrials.gov/ct2/show/NCT01468207?term=NCT01468207&rank=1Accessed May 23, 2016
   Google Scholar
• AbbVieA phase 3 multicenter study of the safety and efficacy of adalimumab in subjects with moderate to severe hidradenitis suppurativa – PIONEER II ClinicalTials.gov, Identifier: NCT01468233 [last updated October 15, 2015]. Available from: https://clinicaltrials.gov/ct2/show/NCT01468233?term=NCT01468233&rank=1Accessed May 23, 2016
   Google Scholar
• KimballABOkunMMWilliamsDATwo phase 3 trials of adalimumab for hidradenitis suppurativaN Engl J Med2016375542243427518661
   PubMed Web of Science ®Google Scholar
• BlokJLLiKBrodmerkelCHorvátovichPJonkmanMFHorváthBUstekinumab in hidradenitis suppurativa: clinical results and a search for potential biomarkers in serumBr J Dermatol2016174483984626641739
   PubMed Web of Science ®Google Scholar
• GulliverWPJemecGBBakerKAExperience with ustekinumab for the treatment of moderate to severe hidradenitis suppurativaJ Eur Acad Dermatol Venereol201226791191421605174
   PubMed Web of Science ®Google Scholar
• SharonVRGarciaMSBagheriSManagement of recalcitrant hidradenitis suppurativa with ustekinumabActa Derm Venereol201292332032122101775
   PubMed Web of Science ®Google Scholar
• BaerveldtEMKappenJHThioHBvan LaarJAvan HagenPMPrensEPSuccessful long-term triple disease control by ustekinumab in a patient with Behcet’s disease, psoriasis and hidradenitis suppurativaAnn Rheum Dis201372462662723148307
   PubMed Web of Science ®Google Scholar
• Santos-PérezMIGarcía-RodicioSDel Olmo-RevueltoMAPozo-RománTUstekinumab for hidradenitis suppurativa: a case reportActas Dermosifiliogr2014105772072224308927
   PubMedGoogle Scholar