Retinoid plus antimicrobial combination treatments for acne

References

• KatsambasADessiniotiCNew and emerging treatments in dermatology: acneDermatol Ther200821869518394082
   PubMed Web of Science ®Google Scholar
• WhiteGMRecent findings in the epidemiologic evidence, classification, and subtypes of acne vulgarisJ Am Acad Dermatol199839S34S379703121
   PubMed Web of Science ®Google Scholar
• GollnickHCurrent concepts of the pathogenesis of acne: implications for drug treatmentDrugs2003631579159612887264
   PubMed Web of Science ®Google Scholar
• PerkinsAChengCHillebrandGMiyamotoKKimballAComparison of the epidemiology of acne vulgaris among Caucasian, Asian, Continental Indian and African American womenJ Eur Acad Dermatol Venereol11252010 [Epub ahead of print].
   Web of Science ®Google Scholar
• GoldbergJLDabadeTSDavisSAFleischerABJrKrowchukDPFeldmanSRChanging Age of Acne Vulgaris Visits: another sign of earlier puberty? Accepted for publication March 19, 2011 by Pediatric Dermatology.
   Google Scholar
• GuptaMAGuptaAKDepression and suicidal ideation in dermatology patients with acne, alopecia areata, atopic dermatitis and psoriasisBr J Dermatol19981398468509892952
   PubMed Web of Science ®Google Scholar
• LasekRJChrenMMAcne vulgaris and the quality of life of adult dermatology patientsArch Dermatol19981344544589554297
   PubMed Web of Science ®Google Scholar
• KooJThe psychosocial impact of acne: patients’ perceptionsJ Am Acad Dermatol199532S26S307738224
   PubMed Web of Science ®Google Scholar
• KrowchukDPStancinTKeskinenRWalkerRBassJAnglinTMThe psychosocial effects of acne on adolescentsPediatr Dermatol199183323381838809
   PubMed Web of Science ®Google Scholar
• KurokawaIDanbyFWJuQNew developments in our understanding of acne pathogenesis and treatmentExp Dermatol20091882183219555434
   PubMed Web of Science ®Google Scholar
• ZouboulisCCAcne and sebaceous gland functionClin Dermatol20042236036615556719
   PubMed Web of Science ®Google Scholar
• LeeDYYamasakiKRudsilJSebocytes express functional cathelicidin antimicrobial peptides and can act to kill propionibacterium acnesJ Invest Dermatol20081281863186618200058
   PubMed Web of Science ®Google Scholar
• KoreckAPivarcsiADobozyAKemenyLThe role of innate immunity in the pathogenesis of acneDermatology20032069610512592074
   PubMed Web of Science ®Google Scholar
• AlestasTGancevicieneRFimmelSMuller-DeckerKZouboulisCCEnzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glandsJ Mol Med200684758716388388
   PubMed Web of Science ®Google Scholar
• MakrantonakiEZouboulisCCTestosterone metabolism to 5alpha-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytesBr J Dermatol200715642843217300229
   PubMed Web of Science ®Google Scholar
• DarlingJALaingAHHarknessRAA survey of the steroids in cows’ milkJ Endocrinol1974622912974411778
   PubMed Web of Science ®Google Scholar
• ChenWTsaiSJLiaoCYHigher levels of steroidogenic acute regulatory protein and type I 3beta-hydroxysteroid dehydrogenase in the scalp of men with androgenetic alopeciaJ Invest Dermatol20061262332233516778788
   PubMed Web of Science ®Google Scholar
• McDowellAValanneSRamageGPropionibacterium acnes types I and II represent phylogenetically distinct groupsJ Clin Microbiol20054332633415634990
   PubMed Web of Science ®Google Scholar
• LeydenJJA review of the use of combination therapies for the treatment of acne vulgarisJ Am Acad Dermatol200349S200S21012963896
   PubMed Web of Science ®Google Scholar
• WolfJEJrKaplanDKrausSJEfficacy and tolerability of combined topical treatment of acne vulgaris with adapalene and clindamycin: a multicenter, randomized, investigator-blinded studyJ Am Acad Dermatol200349S211S21712963897
   PubMed Web of Science ®Google Scholar
• Abdel-NaserMBZouboulisCCClindamycin phosphate/tretinoin gel formulation in the treatment of acne vulgarisExpert Opin Pharmacother200892931293718937624
   PubMed Web of Science ®Google Scholar
• WolfJEJrPotential anti-inflammatory effects of topical retinoids and retinoid analoguesAdv Ther20021910911812201351
   PubMed Web of Science ®Google Scholar
• YentzerBAMcClainRWFeldmanSRDo topical retinoids cause acne to “flare”?J Drugs Dermatol2009879980119746671
   PubMed Web of Science ®Google Scholar
• TanghettiEThe evolution of benzoyl peroxide therapyCutis20088251119202772
   PubMed Web of Science ®Google Scholar
• KinneyMAYentzerBAFleischerABJrFeldmanSRTrends in the treatment of acne vulgaris: are measures being taken to avoid antimicrobial resistance?J Drugs Dermatol2010951952420480795
   PubMed Web of Science ®Google Scholar
• SagranskyMYentzerBAFeldmanSRBenzoyl peroxide: a review of its current use in the treatment of acne vulgarisExpert Opin Pharmacother2009102555256219761357
   PubMed Web of Science ®Google Scholar
• ThiboutotDNew treatments and therapeutic strategies for acneArch Fam Med2000917918710693736
   PubMedGoogle Scholar
• YentzerBAAdeRAFountainJMSimplifying regimens promotes greater adherence and outcomes with topical acne medications: a randomized controlled trialCutis20108610310820919606
   PubMed Web of Science ®Google Scholar
• KooJHow do you foster medication adherence for better acne vulgaris management?Skinmed2003222923314673276
   PubMedGoogle Scholar
• CarrollCLFeldmanSRCamachoFTManuelJCBalkrishnanRAdherence to topical therapy decreases during the course of an 8-week psoriasis clinical trial: commonly used methods of measuring adherence to topical therapy overestimate actual useJ Am Acad Dermatol20045121221615280839
   PubMed Web of Science ®Google Scholar
• YentzerBABaldwinHShalitaAWebsterGFeldmanSROptimizing patient adherence: update on combination acne therapy – teens and beyondJ Drugs Dermatol20109s92s95
   Web of Science ®Google Scholar
• DingSVeltin™ (Clindamycin Phosphate and Tretinoin) Gel 1.2%/0.025%2011 Available at: http://www.accessdata.fda.gov/drugsatfda_docs/nda/2010/050803Orig1s000ChemR.pdf. Accessed May 26, 2011.
   Google Scholar
• RietschelRLDuncanSHClindamycin phosphate used in combination with tretinoin in the treatment of acneInt J Dermatol19832241436219964
   PubMed Web of Science ®Google Scholar
• LeydenJJKrochmalLYaroshinskyATwo randomized, double-blind, controlled trials of 2219 subjects to compare the combination clindamycin/tretinoin hydrogel with each agent alone and vehicle for the treatment of acne vulgarisJ Am Acad Dermatol200654738116384759
   PubMed Web of Science ®Google Scholar
• RichterJRForstromLRKiistalaUOJungEGEfficacy of the fixed 1.2% clindamycin phosphate, 0.025% tretinoin gel formulation (Velac) and a proprietary 0.025% tretinoin gel formulation (Aberela) in the topical control of facial acneJ Eur Acad Dermatol Venereol1998112272339883434
   PubMed Web of Science ®Google Scholar
• ZouboulisCCDerumeauxLDecroixJMaciejewska-UdzielaBCambazardFStuhlertAA multicentre, single-blind, randomized comparison of a fixed clindamycin phosphate/tretinoin gel formulation (Velac) applied once daily and a clindamycin lotion formulation (Dalacin T) applied twice daily in the topical treatment of acne vulgarisBr J Dermatol200014349850510971320
   PubMed Web of Science ®Google Scholar
• LeydenJJWortzmanMA novel gel formulation of clindamycin phosphate-tretinoin is not associated with acne flaringCutis20088215115618792548
   PubMed Web of Science ®Google Scholar
• SchlessingerJMenterAGoldMClinical safety and efficacy studies of a novel formulation combining 1.2% clindamycin phosphate and 0.025% tretinoin for the treatment of acne vulgarisJ Drugs Dermatol2007660761517668526
   PubMedGoogle Scholar
• MedicusZiana® prescribing information http://pi.medicis.us/ziana.pdf. Accessed March 9, 2011.
   Google Scholar
• StiefelVeltin® prescribing information http://www.stiefel.com/US/us_veltin.pdf. Accessed March 9, 2011.
   Google Scholar
• EichenfieldLFWortzmanMA novel gel formulation of 0.25% tretinoin and 1.2% clindamycin phosphate: efficacy in acne vulgaris patients aged 12 to 18 yearsPediatr Dermatol20092625726119706084
   PubMed Web of Science ®Google Scholar
• KircikLHPeredoMIBuckoADSafety of a novel gel formulation of clindamycin phosphate 1.2%-tretinoin 0.025%: results from a 52-week open-label studyCutis20088235836619090341
   PubMed Web of Science ®Google Scholar
• van HoogdalemEJBavenTLSpiegel-MelsenITerpstraIJTransdermal absorption of clindamycin and tretinoin from topically applied anti-acne formulations in manBiopharm Drug Dispos1998195635699872337
   PubMed Web of Science ®Google Scholar
• LookingbillDPChalkerDKLindholmJSTreatment of acne with a combination clindamycin/benzoyl peroxide gel compared with clindamycin gel, benzoyl peroxide gel and vehicle gel: combined results of two double-blind investigationsJ Am Acad Dermatol1997375905959344199
   PubMed Web of Science ®Google Scholar
• LeydenJJBergerRSDunlapFEEllisCNConnollyMALevySFComparison of the efficacy and safety of a combination topical gel formulation of benzoyl peroxide and clindamycin with benzoyl peroxide, clindamycin and vehicle gel in the treatments of acne vulgarisAm J Clin Dermatol20012333911702619
   PubMedGoogle Scholar
• LeydenJJHickmanJGJarrattMTStewartDMLevySFThe efficacy and safety of a combination benzoyl peroxide/clindamycin topical gel compared with benzoyl peroxide alone and a benzoyl peroxide/erythromycin combination productJ Cutan Med Surg20015374211281433
   PubMed Web of Science ®Google Scholar
• TschenEHKatzHIJonesTMA combination benzoyl peroxide and clindamycin topical gel compared with benzoyl peroxide, clindamycin phosphate, and vehicle in the treatment of acne vulgarisCutis20016716516911236229
   PubMed Web of Science ®Google Scholar
• ThiboutotDZaengleinAWeissJWebsterGCalvareseBChenDAn aqueous gel fixed combination of clindamycin phosphate 1.2% and benzoyl peroxide 2.5% for the once-daily treatment of moderate to severe acne vulgaris: assessment of efficacy and safety in 2813 patientsJ Am Acad Dermatol20085979280018805603
   PubMed Web of Science ®Google Scholar
• CunliffeWJHollandKTBojarRLevySFA randomized, double-blind comparison of a clindamycin phosphate/benzoyl peroxide gel formulation and a matching clindamycin gel with respect to microbiologic activity and clinical efficacy in the topical treatment of acne vulgarisClin Ther2002241117113312182256
   PubMed Web of Science ®Google Scholar
• SeidlerEMKimballABMeta-analysis comparing efficacy of benzoyl peroxide, clindamycin, benzoyl peroxide with salicylic acid, and combination benzoyl peroxide/clindamycin in acneJ Am Acad Dermatol201063526220488582
   PubMed Web of Science ®Google Scholar
• ChalkerDKShalitaASmithJGJrSwannRWA double-blind study of the effectiveness of a 3% erythromycin and 5% benzoyl peroxide combination in the treatment of acne vulgarisJ Am Acad Dermatol198399339366227643
   PubMed Web of Science ®Google Scholar
• PoulinYSanchezNPBuckoAA 6-month maintenance therapy with adapalene-benzoyl peroxide gel prevents relapse and continuously improves efficacy among severe acne vulgaris patients: results of a randomized controlled trialBr J Dermatol412011 [Epub ahead of print].
   Web of Science ®Google Scholar
• GoldLSTanJCruz-SantanaAA North American study of adapalene-benzoyl peroxide combination gel in the treatment of acneCutis20098411011619746769
   PubMed Web of Science ®Google Scholar
• GollnickHPDraelosZGlennMJAdapalene-benzoyl peroxide, a unique fixed-dose combination topical gel for the treatment of acne vulgaris: a transatlantic, randomized, double-blind, controlled study in 1670 patientsBr J Dermatol20091611180118919466959
   PubMed Web of Science ®Google Scholar
• ThiboutotDMWeissJBuckoAAdapalene-benzoyl peroxide, a fixed-dose combination for the treatment of acne vulgaris: results of a multicenter, randomized double-blind, controlled studyJ Am Acad Dermatol20075779179917655969
   PubMed Web of Science ®Google Scholar
• TroielliPAAsisBBermejoACommunity study of fixed-combination adapalene 0.1% and benzoyl peroxide 2.5% in acneSkinmed20108172220839420
   PubMedGoogle Scholar
• AndresPPerninCPoncetMAdapalene-benzoyl peroxide once-daily, fixed-dose combination gel for the treatment of acne vulgaris: a randomized, bilateral (split-face), dose-assessment study of cutaneous tolerability in healthy participantsCutis20088127828418441854
   PubMed Web of Science ®Google Scholar
• LoescheCPerninCPoncetMAdapalene 0.1% and benzoyl peroxide 2.5% as a fixed-dose combination gel is as well tolerated as the individual components alone in terms of cumulative irritancyEur J Dermatol20081852452618693154
   PubMed Web of Science ®Google Scholar
• ZouboulisCCFischerTCWohlrabJBarnardJAlioABStudy of the efficacy, tolerability, and safety of 2 fixed-dose combination gels in the management of acne vulgarisCutis20098422322919911678
   PubMed Web of Science ®Google Scholar
• EichenfieldLEJorizzoJLDirschkaTTreatment of 2,453 acne vulgaris patients aged 12–17 years with the fixed-dose adapalene-benzoyl peroxide combination topical gel: efficacy and safetyJ Drugs Dermatol201091395140121061762
   PubMed Web of Science ®Google Scholar
• EadyEAFarmeryMRRossJICoveJHCunliffeWJEffects of benzoyl peroxide and erythromycin alone and in combination against antibiotic-sensitive and -resistant skin bacteria from acne patientsBr J Dermatol19941313313367918006
   PubMed Web of Science ®Google Scholar
• FeldmanSRTanJPoulinYDirschkaTKerroucheNMannaVThe efficacy of adapalene-benzoyl peroxide combination increases with number of acne lesionsJ Am Acad Dermatol2011641085109121439678
   PubMed Web of Science ®Google Scholar