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Clinical Trial Report

Effects of Lactoferrin on Subjective Skin Conditions in Winter: A Preliminary, Randomized, Double-Blinded, Placebo-Controlled Trial

, , , , , , , & ORCID Icon show all
Pages 875-880 | Published online: 02 Dec 2019

References

  • Ashida Y, Ogo M, Denda M. Epidermal interleukin-1alpha generation is amplified at low humidity: implications for the pathogenesis of inflammatory dermatoses. Br J Dermatol. 2001;144(2):238–243. doi:10.1046/j.1365-2133.2001.04007.x11251553
  • Chan H, Chan G, Santos J, Dee K, Co JK. A randomized, double-blind, placebo-controlled trial to determine the efficacy and safety of lactoferrin with vitamin E and zinc as an oral therapy for mild to moderate acne vulgaris. Int J Dermatol. 2017;56(6):686–690. doi:10.1111/ijd.1360728369875
  • Engebretsen KA, Johansen JD, Kezic S, Linneberg A, Thyssen JP. The effect of environmental humidity and temperature on skin barrier function and dermatitis. J Eur Acad Dermatol Venereol. 2016;30(2):223–249. doi:10.1111/jdv.1330126449379
  • García-Montoya IA, Cendón TS, Arévalo-Gallegos S, Rascón-Cruz Q. Lactoferrin a multiple bioactive protein: an overview. Biochimica Biophysica Acta Gen Subj. 2012;1820(3):226–236. doi:10.1016/j.bbagen.2011.06.018
  • Kanda Y. Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics. Bone Marrow Transplant. 2013;48(3):452–458. doi:10.1038/bmt.2012.24423208313
  • Kikuchi K, Kobayashi H, Hirao T, Ito A, Takahashi H, Tagami H. Improvement of mild inflammatory changes of the facial skin induced by winter environment with daily applications of a moisturizing cream. Dermatology. 2003;207(3):269–275. doi:10.1159/00007308914571069
  • Kim J, Ko Y, Park Y-K, Kim N-I, Ha W-K, Cho Y. Dietary effect of lactoferrin-enriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris. Nutrition. 2010;26(9):902–909. doi:10.1016/j.nut.2010.05.01120692602
  • Masson PL, Heremans JF. Lactoferrin in milk from different species. Comp Biochem Physiol. 1971;39(1):119–129.
  • Mueller EA, Trapp S, Frentzel A, Kirch W, Brantl V. Efficacy and tolerability of oral lactoferrin supplementation in mild to moderate acne vulgaris: an exploratory study. Curr Med Res Opin. 2011;27:793–797. doi:10.1185/03007995.2011.55772021303195
  • Murata M, Satoh T, Wakabayashi H, Yamauchi K, Abe F, Nomura Y. Oral administration of bovine lactoferrin attenuates ultraviolet B-induced skin photodamage in hairless mice. J Dairy Sci. 2014;97(2):651–658. doi:10.3168/jds.2013-715324359814
  • Ogasawara K. 8. Revised “ethical guidelines for medical and health research involving human subjects.”. Jpn J Radiol Technol. 2017;73(5):397–402. doi:10.6009/jjrt.2017_JSRT_73.5.397
  • Saraceno R, Gramiccia T, Chimenti S, Valenti P, Pietropaoli M, Bianchi L. Topical lactoferrin can improve stable psoriatic plaque. Giornale Italiano Di Dermatologia E Venereologia. 2014;149(3):335–340.24819761
  • Tong PL, West NP, Cox AJ, et al. Oral supplementation with bovine whey-derived Ig-rich fraction and lactoferrin improves SCORAD and DLQI in atopic dermatitis. J Dermatol Sci. 2017;85(2):143–146. doi:10.1016/j.jdermsci.2016.11.00928012820
  • Wakabayashi H, Yamauchi K, Takase M. Lactoferrin research, technology and applications. Int Dairy J. 2006;16(11):1241–1251. doi:10.1016/j.idairyj.2006.06.013
  • World Medical Association Declaration of Helsinki. Ethical principles for medical research involving human subjects. JAMA. 2013;310(20):2191. doi:10.1001/jama.2013.28105324141714
  • Yamauchi H, Yamazaki W, Kuwata T, Yamaguchi H. Oral administration of bovine lactoferrin for treatment of tinea pedis. A placebo-controlled, double-blind study. Mycoses. 2000;43(5):197–202. doi:10.1046/j.1439-0507.2000.00571.x10948819