Clinical Assessment of New Topical Cream Containing Two Essential Oils Combined with Tretinoin in the Treatment of Acne

References

• Williams HC, Dellavalle RP, Garner S. Acne vulgaris. Lancet. 2012;379:361–372. doi:10.1016/S0140-6736(11)60321-821880356
   PubMed Web of Science ®Google Scholar
• Bek-Thomsen M, Lomholt HB, Kilian M. Acne is not associated with yet-uncultured bacteria. J Clin Microbiol. 2008;46:3355–3360. doi:10.1128/JCM.00799-0818716234
   PubMed Web of Science ®Google Scholar
• Contasot E, French LE. New insights into acne pathogenesis: Propionibacterium acnes activates the inflammasome. J Invest Dermatol. 2014;134:310–313. doi:10.1038/jid.2013.50524424454
   PubMed Web of Science ®Google Scholar
• Ross JJ, Snelling AM, Carnegie E, et al. Antibiotic-resistant acne: lessons from Europe. Brit J Dermatol. 2003;148:467–478. 5. doi:10.1046/j.1365-2133.2003.05067.x12653738
   PubMed Web of Science ®Google Scholar
• Spada G, Gavini E, Cossu M, Rassu G, Carta A, Giunchedi P. Evaluation of the effect of hydroxypropyl-β-cyclodextrin on topical administration of milk thistle extract. Carbohydr Polym. 2013;92(2013):40–47. doi:10.1016/j.carbpol.2012.09.01823218263
   PubMed Web of Science ®Google Scholar
• Cunliffe W, Gollnick HPM. Topical therapy In: Cunliffe W, Gollnick HP, editors. Acne Diagnosis and Management. USA: Martin Dunitz Press; 2001:107–14. 7.
   Google Scholar
• Bassett IB, Pannowitz DL, Barnetson RS. A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne. Med J Aust. 1990;153(8):455–458. doi:10.5694/j.1326-5377.1990.tb126150.x2145499
   PubMed Web of Science ®Google Scholar
• Lalla JK, Nandedkar SY, Paranjape MH, Talreja NB. Clinical trials of ayurvedic formulations in the treatment of acne vulgaris. J Ethnopharmacol. 2001;78(1):99–102. (). doi:10.1016/S0378-8741(01)00323-311585696
   PubMed Web of Science ®Google Scholar
• Orafidiya LO, Agbani EO, Oyedele AO, Babalola OO, Onayemi O. Preliminary clinical tests on topical preparations of Ocimum gratis-simum Linn leaf essential oil for the treatment of acne vulgaris. Clin Drug Investig. 2002;22(5):313–319. doi:10.2165/00044011-200222050-00005
   Web of Science ®Google Scholar
• Yoo J, Park S, Hwang I. A clinical study on the effect of a cream containing Ramulus mori extract and tea tree oil on acne vulgaris and aerobic skin flora. Korean J Dermatol. 2003;41:1136–1141.
   Google Scholar
• Orafidiya L, Agbani EO, Oyedele AO, Babalolab OO, Onayemic O, Aiyeduna FF. The effect of Aloe vera gel on the anti-acne properties of the essential oil of Ocimum gratissimum Linn leaf – a preliminary clinical investigation. Int J Aromather. 2004;14(1):15–21. doi:10.1016/j.ijat.2003.12.005
   Google Scholar
• Enshaieh S, Jooya A, Siadat AH, Iraji F. The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study. Indian J Dermatol Venereol Leprol. 2007;73(1):22–25. doi:10.4103/0378-6323.3064617314442
   PubMed Web of Science ®Google Scholar
• Balambal R, Thiruvengadam KV, Kameswarant L, Janaki VR, Thambiah AS.Ocimum basilicum in acne vulgaris a controlled comparison with a standard regime. J Assoc Physicians India. 1985;33(8):507–508.2932427
   PubMedGoogle Scholar
• Sharquie KE, Noaimi AA, Al-Salih MM.Topical therapy of acne vulgaris using 2% tea lotion in comparison with 5% zinc sulphate solution. Saudi Med J. 2008;29(12):1757–1761.19082228
   PubMed Web of Science ®Google Scholar
• Kim B, Shin S. Antimicrobial and improvement effects of tea tree and lavender oils on acne lesions. J Convergence Inf Technol. 2013;8:339–345.
   Google Scholar
• Kwon HH, Yoon JY, Park SY, Min S, Suh DH. Comparison of clinical and histological effects between lactobacillus-fermented Chamaecyparis obtusa and tea tree oil for the treatment of acne: an eight-week double-blind randomized controlled split-face study. Dermatology. 2014;229(2):102–109. doi:10.1159/00036249125228478
   PubMed Web of Science ®Google Scholar
• Mazzarello V, Donadu MG, Ferrari M, et al. Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations. Clin Pharmacol. 2018;13(10):175–181.
   Google Scholar
• Taleb MH, Abdeltawab NF, Shamma RN, et al. Essential oil as a potential anti-acne topical nanoemulsion-in vitro and in vivo study. Molecules. 2018;23(9). doi:10.3390/molecules23092164
   Web of Science ®Google Scholar
• Kılıç S, Okullu SO, Kurt O, et al. Efficacy of two plant extracts against acne vulgaris: initial results of microbiological tests and cell culture studies. J Cosmet Dermatol. 2019;18(4):1061–1065. doi:10.1111/jocd.1281430414245
   PubMed Web of Science ®Google Scholar
• Fiorini-Puybaret C, Aries MF, Fabre B, et al. Pharmacological properties of Myrtacine® and its potential value in acne treatment. Planta Med. 2011;77(14):1582–1589. doi:10.1055/s-0030-127095521452108
   PubMed Web of Science ®Google Scholar
• De Santis F, Poerio N, Gismondi A, et al. Hydroalcoholic extract from origanum vulgare induces a combined anti-mycobacterial and anti-inflammatory response in innate immune cells. PLoS One. 2019;14(3):e0213150. doi:10.1371/journal.pone.021315030830942
   PubMed Web of Science ®Google Scholar
• Cruciani S, Santaniello S, Garroni G, et al. Myrtus polyphenols, from antioxidants to anti-inflammatory molecules: exploring a network involving cytochromes P450 and vitamin D. Molecules. 2019;24(8). doi:10.3390/molecules24081515
   Web of Science ®Google Scholar
• Del Rosso JQ. Clindamycin phosphate-tretinoin combination gel revisited: status report on a specific formulation used for acne treatment. Cutis. 2017;99(3):179–183.28398420
   PubMed Web of Science ®Google Scholar
• Austin BA, Fleischer AB Jr. The extinction of topical erythromycin therapy for acne vulgaris and concern for the future of topical clindamycin. J Dermatolog Treat. 2017;28(2):145–148. doi:10.1080/09546634.2016.121423427425633
   PubMed Web of Science ®Google Scholar
• Goreshi R, Samrao A, Ehst BD. Un confronto in doppio cieco, randomizzato, bilaterale dell’irritazione cutanea dopo l’applicazione della combinazione di prodotti per l’acne clindamicina/tretinoina e perossido di benzoile/adattoalene. J Drugs Dermatol. 2012;11(12):1422–1426.23377511
   PubMed Web of Science ®Google Scholar
• Chuang LT, Tsa TH, Lien TJ, et al. Ethanolic extract of origanum vulgare suppresses propionibacterium acnes-induced inflammatory responses in human monocyte and mouse ear edema models. Molecules. 2018;23(8):1987. doi:10.3390/molecules23081987
   Web of Science ®Google Scholar