Inhibition of miR-155 Attenuates CD14⁺ Monocyte-Mediated Inflammatory Response and Oxidative Stress in Psoriasis Through TLR4/MyD88/NF-κB Signaling Pathway

References

• Karabay EA, Demir D, Erman AA. Evaluation of monocyte to high-density lipoprotein ratio, lymphocytes, monocytes, and platelets in psoriasis. An Bras Dermatol. 2020;95(1):40–45. doi:10.1016/j.abd.2019.05.002
   PubMed Web of Science ®Google Scholar
• Hamers AAJ, Dinh HQ, Thomas GD, et al. Human monocyte heterogeneity as revealed by high-dimensional mass cytometry. Arterioscler Thromb Vasc Biol. 2019;39(1):25–36. doi:10.1161/ATVBAHA.118.311022
   PubMed Web of Science ®Google Scholar
• Singh TP, Zhang HH, Borek I, et al. Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation. Nat Commun. 2016;7:13581. doi:10.1038/ncomms13581
   PubMed Web of Science ®Google Scholar
• Do JE, Kwon SY, Park S, et al. Effects of vitamin D on expression of Toll-like receptors of monocytes from patients with Behcet’s disease. Rheumatology. 2008;47(6):840–848. doi:10.1093/rheumatology/ken109
   PubMed Web of Science ®Google Scholar
• Takamura N, Yamaguchi Y, Watanabe Y, et al. Downregulated Caveolin-1 expression in circulating monocytes may contribute to the pathogenesis of psoriasis. Sci Rep. 2019;9(1):125. doi:10.1038/s41598-018-36767-5
   PubMed Web of Science ®Google Scholar
• Zhou HB, Huang XF, Cui HJ, et al. miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells. Blood. 2010;116(26):5885–5894. doi:10.1182/blood-2010-04-280156
   PubMed Web of Science ®Google Scholar
• O’Neill LA, Golenbock D, Bowie AG. The history of Toll-like receptors - redefining innate immunity. Nat Rev Immunol. 2013;13(6):453–460.
   PubMed Web of Science ®Google Scholar
• Kim SJ, Kim HM. Dynamic lipopolysaccharide transfer cascade to TLR4/MD2 complex via LBP and CD14. BMB Rep. 2017;50(2):55–57. doi:10.5483/BMBRep.2017.50.2.011
   PubMed Web of Science ®Google Scholar
• Wang Y, Weng H, Song JF, et al. Activation of the HMGB1-TLR4-NF-κB pathway may occur in patients with atopic eczema. Mol Med Rep. 2017;16(3):2714–2720. doi:10.3892/mmr.2017.6942
   PubMed Web of Science ®Google Scholar
• Akira S, Takeda K. Toll-like receptor signalling. Cold Spring Harb Perspect Biol. 2004;4:499–511.
   Google Scholar
• Rommy VB, Laura E, Jaime E. Microglial cell dysregulation in brain aging and neurodegeneration. Front Aging Neurosci. 2015;7(124):124.
   PubMedGoogle Scholar
• Moore CS, Rao VTS, Durafourt BA, et al. miR-155 as a multiple sclerosis-relevant regulator of myeloid cell polarization. Ann Neurol. 2013;74(5):709–720. doi:10.1002/ana.23967
   PubMed Web of Science ®Google Scholar
• Zhou Y, Zhang PX, Zheng XY, et al. miR-155 regulates pro- and anti-inflammatory cytokine expression in human monocytes during chronic hepatitis C virus infection. Ann Transl Med. 2021;9(21):1618. doi:10.21037/atm-21-2620
   PubMed Web of Science ®Google Scholar
• Soonthornchai W, Tangtanatakul P, Meephansan J, et al. Down-regulation of miR-155 after treatment with narrow-band UVB and methotrexate associates with apoptosis of keratinocytes in psoriasis. Asian Pac J Allergy Immunol. 2021;39(3):206–213.
   PubMed Web of Science ®Google Scholar
• Hou RX, Liu RF, Zhao XC, et al. Increased miR-155-5p expression in dermal mesenchymal stem cells of psoriatic patients: comparing the microRNA expression profile by microarray. Genet Mol Res. 2016;15(3). doi:10.4238/gmr.15038631
   Web of Science ®Google Scholar
• Liu F, Fan H, Ren D, et al. TLR9-induced miR-155 and Ets-1 decrease expression of CD1d on B cells in SLE. Eur J Immunol. 2015;45(7):1934–1945. doi:10.1002/eji.201445286
   PubMed Web of Science ®Google Scholar
• Bala S, Tilahun Y, Taha O, et al. Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection. J Transl Med. 2012;10:151. doi:10.1186/1479-5876-10-151
   PubMed Web of Science ®Google Scholar
• El-Ekiaby N, Hamdi N, Negm M, et al. Repressed induction of interferon-related microRNAs miR-146a and miR-155 in peripheral blood mononuclear cells infected with HCV genotype 4. FEBS Open Bio. 2012;2(1):179–186. doi:10.1016/j.fob.2012.07.005
   PubMed Web of Science ®Google Scholar
• Fadime D, Ilknur K, Öznur A, et al. Investigation of TLR1-9 genes and miR-155 expression in dogs infected with canine distemper. Comp Immunol Microbiol Infect Dis. 2021;79:101711. doi:10.1016/j.cimid.2021.101711
   PubMed Web of Science ®Google Scholar
• Husakova M. MicroRNAs in the key events of systemic lupus erythematosus pathogenesis. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2016;160(3):327–342. doi:10.5507/bp.2016.004
   PubMed Web of Science ®Google Scholar
• Wen Y, Zhang XJ, Dong LP, et al. Acetylbritannilactone modulates microRNA-155-mediated inflammatory response in ischemic cerebral tissues. Mol Med. 2015;21(1):197–209. doi:10.2119/molmed.2014.00199
   PubMed Web of Science ®Google Scholar
• Akhter N, Madhoun A, Arefanian H, et al. Oxidative stress induces expression of the Toll-like receptors (TLRs) 2 and 4 in the human peripheral blood mononuclear cells: implications for metabolic inflammation. Cell Physiol Biochem. 2019;53(1):1–18.
   PubMedGoogle Scholar
• Chiu YG, Shao T, Feng C. CD16 (FcRγIII) as a potential marker of osteoclast precursors in psoriatic arthritis. Arthritis Res Ther. 2010;12(1):R14. doi:10.1186/ar2915
   PubMed Web of Science ®Google Scholar
• Yamanaka K, Umezawa Y, Yamagiwa A, et al. Biologic therapy improves psoriasis by decreasing the activity of monocytes and neutrophils. J Dermatol. 2014;41(8):679–685.
   PubMed Web of Science ®Google Scholar
• Yang X, Wang H. miRNAs flowing up and down: the concerto of psoriasis. Front Med. 2021;8:646796.
   Web of Science ®Google Scholar
• Xu L, Len H, Shi X, et al. MiR-155 promotes cell proliferation and inhibits apoptosis by PTEN signaling pathway in the psoriasis. Biomed Pharmacother. 2017;90:524–530. doi:10.1016/j.biopha.2017.03.105
   PubMed Web of Science ®Google Scholar
• Li C, He H, Zhu M, et al. Molecular characterisation of porcine miR-155 and its regulatory roles in the TLR3/TLR4 pathways. Dev Comp Immunol. 2013;39(1–2):110–116. doi:10.1016/j.dci.2012.01.001
   PubMed Web of Science ®Google Scholar
• Garg A, Aggarwal BB. Nuclear transcription factor-κB as a target for cancer drug development. Leukemia. 2002;16:1053–1068.
   PubMed Web of Science ®Google Scholar
• Taniguchi K, Karin M. NF-κB, inflammation, immunity and cancer: coming of age. Nat Rev Immunol. 2018;18(5):309–324.
   PubMed Web of Science ®Google Scholar
• Kocic H, Damiani G, Stamenkovic B, et al. Dietary compounds as potential modulators of microRNA expression in psoriasis. Ther Adv Chronic Dis. 2019;10:204062231986480. doi:10.1177/2040622319864805
   Web of Science ®Google Scholar
• Shi Y, Li K, Xu K, et al. MiR-155-5p accelerates cerebral ischemia-reperfusion injury via targeting DUSP14 by regulating NF-κB and MAPKs signaling pathways. Eur Rev Med Pharmacol Sci. 2020;24(3):1408–1419.
   PubMed Web of Science ®Google Scholar
• Ge X, Tang P, Rong Y, et al. Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular endothelial cells after traumatic spinal cord injury. Redox Biol. 2021;41:101932.
   PubMed Web of Science ®Google Scholar
• Wang Y, Branicky R, Noë A, Hekimi S. Superoxide dismutases: dual roles in controlling ROS damage and regulating ROS signaling. J Cell Biol. 2018;217(6):1915–1928. doi:10.1083/jcb.201708007
   PubMed Web of Science ®Google Scholar
• Yang ZB, Chen WW, Chen HP, et al. MiR-155 aggravated septic liver injury by oxidative stress-mediated ER stress and mitochondrial dysfunction via targeting Nrf-2. Exp Mol Pathol. 2018;105(3):387–394. doi:10.1016/j.yexmp.2018.09.003
   PubMed Web of Science ®Google Scholar
• Fu X, He HD, Li CJ, et al. MicroRNA-155 deficiency attenuates inflammation and oxidative stress in experimental autoimmune prostatitis in a TLR4-dependent manner. Kaohsiung J Med Sci. 2020;36(9):712–720. doi:10.1002/kjm2.12229
   PubMed Web of Science ®Google Scholar
• Jung S, Kim S, Lee C, et al. Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation. Oncotarget. 2016;7(38):62559–62571. doi:10.18632/oncotarget.11537
   PubMedGoogle Scholar