Topical Curcumin as Chemoprotector Against Photoproducts Production: The Role of Cyclobutyl Pyrimidine Dimers, 8-Hydroxy2ʹDeoxyguanosine Expression and Epidermal Hyperplasia in Acute and Chronic UVB-Induced Mice

References

• Rünger TM. Cutaneous Photobiology. In: Kang S, Amagai M, Bruckner AL, Enk AH, Morgolis DJ, McMichael AJ, editors. Fitzpatrick’s Dermatology. 9th ed. McGraw-Hill Education; 2019:265–288.
   Google Scholar
• Streilein JW. Suceptibility: posible relationship to photoaging and photocarcinogenesis. In: Gilchrest B, editor. Photodamage. Oxford: Wiley-Blackwell; 1995:68–79.
   Google Scholar
• Soehnge H, Ouhtit A, Ananthaswamy ON. Mechanisms of induction of skin cancer by UV radiation. Front Biosci. 1997;2:d538–51. doi:10.2741/A211
   PubMedGoogle Scholar
• D’Orazio J, Jarrett S, Amaro-Ortiz A, Scott T. UV radiation and the skin. Int J Mol Sci. 2013;14(6):12222–12248. doi:10.3390/ijms140612222
   PubMed Web of Science ®Google Scholar
• Nishisgori C. Current concept of photocarcinogenesis. Photochem Photobiol Sci. 2015;14(9):1713–1721. doi:10.1039/C5PP00185D
   PubMed Web of Science ®Google Scholar
• Ouhtit A, Muller HK, Davis DW, Ullrich SE, McConkey D, Ananthaswamy HN. Temporal events in skin injury and the early adaptive responses in ultraviolet-irradiated mouse skin. Am J Pathol. 2000;156(1):201–207. doi:10.1016/S0002-9440(10)64720-7
   PubMed Web of Science ®Google Scholar
• Wolf P, Donawho CK, Kripke ML. Effect of sunscreens on UV radiation-induced enhancement of melanoma growth in mice. JNCI. 1994;86(2):99–105. doi:10.1093/jnci/86.2.99
   PubMedGoogle Scholar
• Scott TL, Christian PA, Kesler MV, et al. Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation. Exp Dermatol. 2012;21(10):771–777. doi:10.1111/exd.12012
   PubMed Web of Science ®Google Scholar
• Ali RE, Rattan SI. Curcumin’s biphasic hormetic response on proteasome activity and heat-shock protein synthesis in human keratinocytes. Ann N Y Acad Sci. 2006;1067:394–399. doi:10.1196/annals.1354.056
   PubMed Web of Science ®Google Scholar
• Miskad UA, Semba S, Kato H, et al. High PRL-3 expression in human gastric cancer is a marker of metastasis and grades of malignancies: an in situ hybridization study. Virchows Archiv. 2007;450(3):303–310. doi:10.1007/s00428-006-0361-8
   PubMed Web of Science ®Google Scholar
• Chan WY, Cheung KK, Schorge JO, et al. Bcl-2 and p53 protein expression, apoptosis, and p53 mutation in human epithelial ovarian cancers. Am J Pathol. 2000;156(2):409–417. doi:10.1016/S0002-9440(10)64744-X
   PubMed Web of Science ®Google Scholar
• Tsai KD, Lin JC, Yang S, et al. Curcumin protects against UVB-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular markers in carcinogenesis. Evid Based Complementary Altern Med. 2012;2012:1–11. doi:10.1155/2012/593952
   Web of Science ®Google Scholar
• Huang MT, Ma W, Yen P, et al. Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis. Carcinogenesis. 1997;18(1):83–88. doi:10.1093/carcin/18.1.83
   PubMed Web of Science ®Google Scholar
• Majidinia M, Bishayee A, Yousefi B. Polyphenols: major regulators of key components of DNA damage response in cancer. DNA Repair. 2019;82:102679. doi:10.1016/j.dnarep.2019.102679
   PubMed Web of Science ®Google Scholar
• Lüer SC, Goette J, Troller R, Aebi C. Synthetic versus natural curcumin: bioequivalence in an in vitro oral mucositis model. BMC Complement Altern Med. 2014;14(1):53. doi:10.1186/1472-6882-14-53
   PubMed Web of Science ®Google Scholar
• Taylor S, Diffey B. Simple dosage guide for suncreans will help users. BMJ. 2002;324(7352):1526. doi:10.1136/bmj.324.7352.1526/a
   PubMedGoogle Scholar
• Mitchell DL, Greinert R, De Gruijl FR, et al. Effects of chronic low-dose ultraviolet B radiation on DNA damage and repair in mouse skin. Cancer Res. 1999;59(12):2875–2884.
   PubMed Web of Science ®Google Scholar
• Sutherland BM, Harber LC, Kochevar IE. Pyrimidine dimer formation and repair in human skin. Cancer Res. 1980;40(9):3181–3185.
   PubMed Web of Science ®Google Scholar
• Park JM, Kang TH. Transcriptional and posttranslational regulation of nucleotide excision repair: the guardian of the genome against ultraviolet radiation. Int J Mol Sci. 2016;17(11):1840. doi:10.3390/ijms17111840
   PubMed Web of Science ®Google Scholar
• Zhou H-Y, Sun -Y-Y, Chang P, Huang H-C. Curcumin inhibits cell damage and apoptosis caused by thapsigargin-induced endoplasmic reticulum stress involving the recovery of mitochondrial function mediated by mitofusin-2. Neurotox Res. 2022;40(2):449–460. doi:10.1007/s12640-022-00481-y
   PubMed Web of Science ®Google Scholar
• Hassan F-U, Rehman MS-U, Khan MS, et al. Curcumin as an alternative epigenetic modulator: mechanism of action and potential effects. Front Genet. 2019;10:514. doi:10.3389/fgene.2019.00514
   PubMed Web of Science ®Google Scholar
• Huei Chen H, Tong Rong J, Sheau Farn Y. Inhibitory effect of curcumin, an anti-inflammatory agent, on vascular smooth muscle cell proliferation. Eur J Pharmacol. 1992;221(2–3):381–384. doi:10.1016/0014-2999(92)90727-L
   PubMed Web of Science ®Google Scholar
• Sharma K, Agrawal S, Gupta M. Development and validation of UV spectrophotometric method for the estimation of curcumin in bulk drug and pharmaceutical dosage forms. Int J Drug Dev Res. 2012;4(2):375–380.
   Google Scholar
• Cao J, Jia L, Zhou H-M, Liu Y, Zhong L-F. Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells. Toxicol Sci. 2006;91(2):476–483. doi:10.1093/toxsci/kfj153
   PubMed Web of Science ®Google Scholar
• Lin JK, Lin-Shiau SY. Mechanisms of cancer chemoprevention by curcumin. Proc Natl Sci Counc. 2001;25(2):59–66.
   PubMedGoogle Scholar
• Okada K, Wangpoengtrakul C, Tanaka T, Toyokuni S, Uchida K, Osawa T. Curcumin and especially tetrahydrocurcumin ameliorate oxidative stress-induced renal injury in mice. J Nutr. 2001;131(8):2090–2095. doi:10.1093/jn/131.8.2090
   PubMed Web of Science ®Google Scholar
• Priyadarsini KI, Maity DK, Naik GH, et al. Role of phenolic O-H and methylene hydrogen on the free radical reactions and antioxidant activity of curcumin. Free Radic Biol Med. 2003;35(5):475–484. doi:10.1016/S0891-5849(03)00325-3
   PubMed Web of Science ®Google Scholar
• Y-p L, Chang RL, Lou Y-R, et al. Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate-and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in mouse epidermis. Carcinogenesis. 1994;15(10):2363–2370. doi:10.1093/carcin/15.10.2363
   PubMed Web of Science ®Google Scholar
• Khandelwal AR, Rong X, Moore-Medlin T, et al. Photopreventive effect and mechanism of AZD4547 and curcumin C3 complex on UVB-induced epidermal hyperplasia. Cancer Prev Res. 2016;9(4):296–304. doi:10.1158/1940-6207.CAPR-15-0366
   PubMed Web of Science ®Google Scholar
• Yehuda Greenwald M B, Frušić-Zlotkin M, Soroka Y, et al. Curcumin protects skin against UVB-induced cytotoxicity via the keap1-Nrf2 pathway: the use of a microemulsion delivery system. Oxid Med Cell Longev. 2017;2017:5205471. doi:10.1155/2017/5205471
   PubMed Web of Science ®Google Scholar