585
Views
1
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

The Association of Serum Adipokines, Insulin Resistance and Vitamin D Status in Male Patients with Androgenetic Alopecia

, , ORCID Icon, , , , , , , & ORCID Icon show all
Pages 419-427 | Received 14 Nov 2022, Accepted 08 Feb 2023, Published online: 13 Feb 2023

References

  • Sheikh FZ, Butt G, Hafeez R, Maqsood A, Altaf F, Hussain I. Association of early-onset androgenetic alopecia and metabolic syndrome. J Coll Physicians Surg Pak. 2021;31(2):123–127.
  • Yang -C-C, Hsieh F-N, Lin L-Y, Hsu C-K, Sheu H-M, Chen W. Higher body mass index is associated with greater severity of alopecia in men with male-pattern androgenetic alopecia in Taiwan: a cross-sectional study. J Am Acad Dermatol. 2014;70(2):297–302.e1. doi:10.1016/j.jaad.2013.09.036
  • Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol. 2005;115(5):911–920. doi:10.1016/j.jaci.2005.02.023
  • Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol. 2011;11(2):85–97. doi:10.1038/nri2921
  • Chatterjee TK, Stoll LL, Denning GM, et al. Proinflammatory phenotype of perivascular adipocytes: influence of high-fat feeding. Circ Res. 2009;104(4):541–549. doi:10.1161/CIRCRESAHA.108.182998
  • Iguchi M, Aiba S, Yoshino Y, Tagami H. Human follicular papilla cells carry out nonadipose tissue production of leptin. J Invest Dermatol. 2001;117(6):1349–1356. doi:10.1046/j.0022-202x.2001.01606.x
  • Yang CC, Sheu HM, Chung PL, et al. Leptin of dermal adipose tissue is differentially expressed during the hair cycle and contributes to adipocyte-mediated growth inhibition of anagen-phase vibrissa hair. Exp Dermatol. 2015;24(1):57–60. doi:10.1111/exd.12566
  • Sumikawa Y, Inui S, Nakajima T, Itami S. Hair cycle control by leptin as a new anagen inducer. Exp Dermatol. 2014;23(1):27–32. doi:10.1111/exd.12286
  • Yang CC, Chung PL, Lin LY, Hughes MW, Tsai YS. Higher plasma leptin is associated with higher risk of androgenetic alopecia in men. Exp Dermatol. 2017;26(6):524–526. doi:10.1111/exd.13369
  • Matilainen V, Koskela P, Keinänen-Kiukaanniemi S. Early androgenetic alopecia as a marker of insulin resistance. Lancet. 2000;356(9236):1165–1166. doi:10.1016/S0140-6736(00)02763-X
  • Nimitphong H, Park E, Lee M-J. Vitamin D regulation of adipogenesis and adipose tissue functions. Nutr Res Pract. 2020;14(6):553–567. doi:10.4162/nrp.2020.14.6.553
  • Szymczak-Pajor I, Miazek K, Selmi A, Balcerczyk A, Śliwińska A. The action of vitamin d in adipose tissue: is there the link between vitamin D deficiency and adipose tissue-related metabolic disorders? Int J Mol Sci. 2022;23(2):956. doi:10.3390/ijms23020956
  • Gerkowicz A, Chyl-Surdacka K, Krasowska D, Chodorowska G. The role of vitamin D in non-scarring alopecia. Int J Mol Sci. 2017;18(12):2653. doi:10.3390/ijms18122653
  • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28(7):412–419. doi:10.1007/BF00280883
  • Lolli F, Pallotti F, Rossi A, et al. Androgenetic alopecia: a review. Endocrine. 2017;57(1):9–17. doi:10.1007/s12020-017-1280-y
  • Kanti V, Messenger A, Dobos G, et al. Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men - short version. J Eur Acad Dermatol Venereol. 2018;32(1):11–22. doi:10.1111/jdv.14624
  • Heymann WR. The inflammatory component of androgenetic alopecia. J Am Acad Dermatol. 2022;86(2):301–302. doi:10.1016/j.jaad.2021.11.013
  • González-González JG, Mancillas-Adame LG, Fernández-Reyes M, et al. Androgenetic alopecia and insulin resistance in young men. Clin Endocrinol. 2009;71(4):494–499. doi:10.1111/j.1365-2265.2008.03508.x
  • Arias-Santiago S, Gutiérrez-Salmerón MT, Buendía-Eisman A, Girón-Prieto MS, Naranjo-Sintes R. Hypertension and aldosterone levels in women with early-onset androgenetic alopecia. Br J Dermatol. 2010;162(4):786–789. doi:10.1111/j.1365-2133.2009.09588.x
  • Arias-Santiago S, Gutiérrez-Salmerón MT, Castellote-Caballero L, Buendía-Eisman A, Naranjo-Sintes R. Androgenetic alopecia and cardiovascular risk factors in men and women: a comparative study. J Am Acad Dermatol. 2010;63(3):420–429. doi:10.1016/j.jaad.2009.10.018
  • Wauters M, Considine RV, Yudkin JS, Peiffer F, De Leeuw I, Van Gaal LF. Leptin levels in type 2 diabetes: associations with measures of insulin resistance and insulin secretion. Horm Metab Res. 2003;35(2):92–96. doi:10.1055/s-2003-39054
  • Anandaraj AA, Syed Ismail PM, Namis SM, Bajnaid YJ, Shetty SB, Almutairi KM. Association of selected adipocytokines and inflammatory markers on body mass index in type 2 diabetes patients in Saudi Arabia and as risk factors to cardiovascular disease. Curr Diabetes Rev. 2017;13(3):330–335. doi:10.2174/1573399812666160614014254
  • Fasshauer M, Blüher M. Adipokines in health and disease. Trends Pharmacol Sci. 2015;36(7):461–470. doi:10.1016/j.tips.2015.04.014
  • Frühbeck G, Catalán V, Rodríguez A, Gómez-Ambrosi J. Adiponectin-leptin ratio: a promising index to estimate adipose tissue dysfunction. Relation with obesity-associated cardiometabolic risk. Adipocyte. 2018;7(1):57–62. doi:10.1080/21623945.2017.1402151
  • Frühbeck G, Catalán V, Rodríguez A, et al. Adiponectin-leptin ratio is a functional biomarker of adipose tissue inflammation. Nutrients. 2019;11(2):454. doi:10.3390/nu11020454
  • Marques-Oliveira GH, Silva TM, Lima WG, Valadares HMS, Chaves VE. Insulin as a hormone regulator of the synthesis and release of leptin by white adipose tissue. Peptides. 2018;106:49–58. doi:10.1016/j.peptides.2018.06.007
  • Zerwekh JE. Blood biomarkers of vitamin D status. Am J Clin Nutr. 2008;87(4):1087S–1091S. doi:10.1093/ajcn/87.4.1087S
  • Abbas MA. Physiological functions of Vitamin D in adipose tissue. J Steroid Biochem Mol Biol. 2017;165(Pt B):369–381. doi:10.1016/j.jsbmb.2016.08.004
  • Peters KE, Davis WA, Beilby J, Hung J, Bruce DG, Davis TME. The relationship between circulating adiponectin, ADIPOQ variants and incident cardiovascular disease in type 2 diabetes: the Fremantle Diabetes Study. Diabetes Res Clin Pract. 2018;143:62–70. doi:10.1016/j.diabres.2018.06.005
  • Kechichian E, Ezzedine K. Vitamin D and the skin: an update for dermatologists. Am J Clin Dermatol. 2018;19(2):223–235. doi:10.1007/s40257-017-0323-8
  • Hajimohammadi M, Shab-Bidar S, Neyestani TR. Vitamin D and serum leptin: a systematic review and meta-analysis of observational studies and randomized controlled trials. Eur J Clin Nutr. 2017;71(10):1144–1153. doi:10.1038/ejcn.2016.245