Ineffective esophageal motility and the vagus: current challenges and future prospects

References

• BlonskiWVelaMSafderAHilaACastellDORevised criterion for diagnosis of ineffective esophageal motility is associated with more frequent dysphagia and greater bolus transit abnormalitiesAm J Gastroenterol2008103369970418341490
   PubMed Web of Science ®Google Scholar
• KahrilasPJBredenoordAJFoxMInternational High Resolution Manometry Working GroupThe Chicago classification of esophageal motility disorders, v3.0Neurogastroenterol Motil201527216017425469569
   PubMed Web of Science ®Google Scholar
• ConchilloJMNguyenNQSamsomMHollowayRHSmoutAJMultichannel intraluminal impedance monitoring in the evaluation of patients with non-obstructive DysphagiaAm J Gastroenterol2005100122624263216393211
   PubMed Web of Science ®Google Scholar
• ScheerensCTackJRommelNBuspirone, a new drug for the management of patients with ineffective esophageal motilityUnited European Gastroenterol J201533261265
   PubMed Web of Science ®Google Scholar
• Abdel JalilAACastellDOIneffective esophageal motility (IEM): the old-new Frontier in esophagologyCurr Gastroenterol Rep2016181126685862
   PubMedGoogle Scholar
• HoSCChangCSWuCYChenGHIneffective esophageal motility is a primary motility disorder in gastroesophageal reflux diseaseDig Dis Sci200247365265611911355
   PubMed Web of Science ®Google Scholar
• NguyenNQTippettMSmoutAJHollowayRHRelationship between pressure wave amplitude and esophageal bolus clearance assessed by combined manometry and multichannel intraluminal impedance measurementAm J Gastroenterol2006101112476248417029613
   PubMed Web of Science ®Google Scholar
• TutuianRCastellDOClarification of the esophageal function defect in patients with manometric ineffective esophageal motility: studies using combined impedance-manometryClin Gastroenterol Hepatol20042323023615017607
   PubMed Web of Science ®Google Scholar
• LinZYimBGawronAImamHKahrilasPJPandolfinoJEThe four phases of esophageal bolus transit defined by high-resolution impedance manometry and fluoroscopyAm J Physiol Gastrointest Liver Physiol20143074G437G44424970774
   PubMed Web of Science ®Google Scholar
• van HoeijFBSmoutAJBredenoordAJPredictive value of routine esophageal high-resolution manometry for gastro-esophageal reflux diseaseNeurogastroenterol Motil20152796397025930019
   PubMed Web of Science ®Google Scholar
• MelloMDShriverARLiYPatelAGyawaliCPIneffective esophageal motility phenotypes following fundoplication in gastroesophageal reflux diseaseNeurogastroenterol Motil201628229229826575034
   PubMed Web of Science ®Google Scholar
• PageAJBlackshawLARoles of gastro-esophageal afferents in the mechanisms and symptoms of reflux diseaseCanningBJSpinaDHandbook of Experimental Pharmacology194 edSpringer VerlagBerlin, Germany2009227
   Google Scholar
• SweisRAnggiansahAWongTBradyGFoxMAssessment of esophageal dysfunction and symptoms during and after a standardized test meal: development and clinical validation of a new methodology utilizing high-resolution manometryNeurogastroenterol Motil201426221522824238326
   PubMed Web of Science ®Google Scholar
• FornariFBraviIPenaginiRTackJSifrimDMultiple rapid swallowing: a complementary test during standard oesophageal manometryNeurogastroenterol Motil200921718.e4119222762
   PubMed Web of Science ®Google Scholar
• MinYWShinISonHJRheePLMultiple rapid swallow maneuver enhances the clinical utility of high-resolution manometry in patients showing ineffective esophageal motilityMedicine (Baltimore)20159440e166926448010
   PubMed Web of Science ®Google Scholar
• JeanABrain stem control of swallowing: neuronal network and cellular mechanismsPhysiol Rev200181292996911274347
   PubMed Web of Science ®Google Scholar
• ErtekinCAydogduINeurophysiology of swallowingClin Neurophysiol2003114122226224414652082
   PubMed Web of Science ®Google Scholar
• PatersonWGDiamantNEEsophageal motor physiologyShakerREAPrinciples of Diglutition: A Multidisciplinary Text for Swallowing and Its DisordersNew YorkSpringer2013303318
   Google Scholar
• ReynoldsRPEl-SharkawyTYDiamantNELower esophageal sphincter function in the cat: role of central innervation assessed by transient vagal blockadeAm J Physiol19842466 Pt 1G666G6746742118
   PubMed Web of Science ®Google Scholar
• GoyalRKPatersonWGEsophageal motilityPollockDMComprehensive PhysiologyBethesda, MDThe American Physiological Society2011865908
   Google Scholar
• PreiksaitisHGDiamantNEMyogenic mechanism for peristalsis in the cat esophagusAm J Physiol19992772 Pt 1G306G31310444444
   PubMed Web of Science ®Google Scholar
• BerezinIDanielEEHuizingaJDUltrastructure of interstitial cells of Cajal in the canine distal esophagusCan J Physiol Pharmacol1994729104910597842387
   PubMed Web of Science ®Google Scholar
• ZarateNWangXYTougasGIntramuscular interstitial cells of Cajal associated with mast cells survive nitrergic nerves in achalasiaNeurogastroenterol Motil200618755656816771771
   PubMed Web of Science ®Google Scholar
• ChenJHWangXYLiuLWOn the origin of rhythmic contractile activity of the esophagus in early achalasia, a clinical case studyFront Neurosci201377723734090
   PubMed Web of Science ®Google Scholar
• PatersonWGEsophageal and lower esophageal sphincter response to balloon distention in patients with achalasiaDig Dis Sci19974211061129009124
   PubMed Web of Science ®Google Scholar
• HuizingaJDThunebergLKluppelMMalyszJMikkelsenHBBernsteinAW/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activityNature199537365123473497530333
   PubMed Web of Science ®Google Scholar
• HuizingaJDThunebergLVanderwindenJMRumessenJJInterstitial cells of Cajal as targets for pharmacological intervention in gastrointestinal motor disordersTrends Pharmacol Sci199718103934039357324
   PubMed Web of Science ®Google Scholar
• StreutkerCJHuizingaJDDrimanDKRiddellRHInterstitial cells of Cajal in health and disease. Part I: normal ICC structure and function with associated motility disordersHistopathology200750217618917222246
   PubMed Web of Science ®Google Scholar
• ShafikAEl-SibaiOShafikIShafikAElectroesophagogram in gastroesophageal reflux disease with a new theory on the pathogenesis of its electric changesBMC Surg200441315462680
   PubMedGoogle Scholar
• BerthoudHRPattersonLMNeumannFNeuhuberWLDistribution and structure of vagal afferent intraganglionic laminar endings (IGLEs) in the rat gastrointestinal tractAnat Embryol (Berl)199719521831919045988
   PubMedGoogle Scholar
• BeyakMJBulmerDCEJiangWKeatingCRongWGrundyDExtrinsic sensory afferent nerves innervating the gastrointestinal tractJohnsonLRPhysiology of the Gastrointestinal Tract4th edAcademic Press2006685727
   Google Scholar
• PowleyTLWangXYFoxEAPhillipsRJLiuLWHuizingaJDUltrastructural evidence for communication between intramuscular vagal mechanoreceptors and interstitial cells of Cajal in the rat fundusNeurogastroenterol Motil2008201697917931338
   PubMed Web of Science ®Google Scholar
• HuizingaJDReedDEBerezinISurvival dependency of intramuscular ICC on vagal afferent nerves in the cat esophagusAm J Physiol Regul Integr Comp Physiol20082942R302R31018003789
   PubMed Web of Science ®Google Scholar
• PowleyTLHudsonCNMcAdamsJLBaronowskyEAPhillipsRJVagal intramuscular arrays: the specialized mechanoreceptor arbors that innervate the smooth muscle layers of the stomach examined in the ratJ Comp Neurol2016524471373726355387
   PubMed Web of Science ®Google Scholar
• PowleyTLBaronowskyEAGilbertJMVagal afferent innervation of the lower esophageal sphincterAuton Neurosci2013177212914223583280
   PubMed Web of Science ®Google Scholar
• TacheYThe parasympathetic nervous system in the pathophysiology of the gastrointestinal tractBolisCLLicinioJGovoniSHandbook of the Autonomic Nervous SystemBaselMarcel Dekker Inc2003463504
   Google Scholar
• BoeckxstaensGEThe lower oesophageal sphincterNeurogastroenterol Motil200517Suppl 1132115836451
   PubMed Web of Science ®Google Scholar
• MartinoRTerraultNEzerzerFMikulisDDiamantNEDysphagia in a patient with lateral medullary syndrome: insight into the central control of swallowingGastroenterology2001121242042611487551
   PubMed Web of Science ®Google Scholar
• DentJHollowayRHToouliJDoddsWJMechanisms of lower oesophageal sphincter incompetence in patients with symptomatic gastrooesophageal refluxGut1988298102010283410327
   PubMed Web of Science ®Google Scholar
• SifrimDJanssensJVantrappenGTransient lower esophageal sphincter relaxations and esophageal body muscular contractile response in normal humansGastroenterology199611036596688608873
   PubMed Web of Science ®Google Scholar
• KuoPBraviIMarreddyUAzizQSifrimDPostprandial cardiac vagal tone and transient lower esophageal sphincter relaxation (TLESR)Neurogastroenterol Motil20132510841.e63923895280
   PubMed Web of Science ®Google Scholar
• AmarasiriDLPathmeswaranADassanayakeASde SilvaAPRanasinhaCDde SilvaHJEsophageal motility, vagal function and gastroesophageal reflux in a cohort of adult asthmaticsBMC Gastroenterol20121214023057471
   PubMed Web of Science ®Google Scholar
• BabicTAmblerJBrowningKNTravagliRACharacterization of synapses in the rat subnucleus centralis of the nucleus tractus solitariusJ Neurophysiol2015113246647425355962
   PubMed Web of Science ®Google Scholar
• BautistaTGSunQJPilowskyPMThe generation of pharyngeal phase of swallow and its coordination with breathing: interaction between the swallow and respiratory central pattern generatorsProg Brain Res201421225327525194202
   PubMed Web of Science ®Google Scholar
• BeyakMJVisceral afferents – determinants and modulation of excitabilityAuton Neurosci20101531–2697819674942
   PubMed Web of Science ®Google Scholar
• BrowningKNTravagliRACentral nervous system control of gastrointestinal motility and secretion and modulation of gastrointestinal functionsCompr Physiol2014441339136825428846
   PubMed Web of Science ®Google Scholar
• TougasGKamathMWatteelGModulation of neurocardiac function by oesophageal stimulation in humansClin Sci (Lond)19979221671749059318
   PubMed Web of Science ®Google Scholar
• BravoJAForsythePChewMVIngestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerveProc Natl Acad Sci U S A201110838160501605521876150
   PubMed Web of Science ®Google Scholar
• BercikPParkAJSinclairDThe anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communicationNeurogastroenterol Motil201123121132113921988661
   PubMed Web of Science ®Google Scholar
• KhoshdelAVerduEFKunzeWMcLeanPBergonzelliGHuizingaJDBifidobacterium longum NCC3001 inhibits AH neuron excitabilityNeurogastroenterol Motil2013257e478e48423663494
   PubMed Web of Science ®Google Scholar
• GoehlerLELyteMGaykemaRPInfection-induced viscerosensory signals from the gut enhance anxiety: implications for psychoneuroimmunologyBrain Behav Immun200721672172617428636
   PubMed Web of Science ®Google Scholar
• De PalmaGBlennerhassettPLuJMicrobiota and host determinants of behavioural phenotype in maternally separated miceNat Commun20156773526218677
   PubMed Web of Science ®Google Scholar
• CollinsSMSuretteMBercikPThe interplay between the intestinal microbiota and the brainNat Rev Microbiol2012101173574223000955
   PubMed Web of Science ®Google Scholar
• BarbaraGCremonCStanghelliniVInflammatory bowel disease and irritable bowel syndrome: similarities and differencesCurr Opin Gastroenterol201430435235824811054
   PubMed Web of Science ®Google Scholar
• MartinREGoodyearBGGatiJSMenonRSCerebral cortical representation of automatic and volitional swallowing in humansJ Neurophysiol200185293895011160524
   PubMed Web of Science ®Google Scholar
• CechettoDFCortical control of the autonomic nervous systemExp Physiol201499232633124121283
   PubMed Web of Science ®Google Scholar
• JeanALe noyau du faisceau solitaire: Aspects neuroanatomiques, neurochimiques et fonctionnels [The nucleus tractus solitarius: neuroanatomic, neurochemical and functional aspects]Arch Int Physiol Biochim Biophys1991995A3A52 French1720691
   PubMed Web of Science ®Google Scholar
• CastleMComoliELoewyADAutonomic brainstem nuclei are linked to the hippocampusNeuroscience2005134265766915975727
   PubMed Web of Science ®Google Scholar
• BourkeJSoldanJSilkDBAzizQLibbyGWIdiopathic’ intestinal failure – the importance of identifying and treating primary psychopathologyNeurogastroenterol Motil201224324225122188396
   PubMed Web of Science ®Google Scholar
• SchwaberJSKappBSHigginsGThe origin and extent of direct amygdala projections to the region of the dorsal motor nucleus of the vagus and the nucleus of the solitary tractNeurosci Lett198020115206189032
   PubMed Web of Science ®Google Scholar
• BakerLHLiebermanDOehlkeMPsychological distress in patients with gastroesophageal reflux diseaseAm J Gastroenterol19959010179718037572897
   PubMed Web of Science ®Google Scholar
• HornbyPJCentral neurocircuitry associated with emesisAm J Med2001111Suppl 8A106S112S11749934
   PubMed Web of Science ®Google Scholar
• SmoutAFoxMWeak and absent peristalsisNeurogastroenterol Motil201224Suppl 1404722248107
   PubMed Web of Science ®Google Scholar
• AndrewsPLSangerGJAbdominal vagal afferent neurones: an important target for the treatment of gastrointestinal dysfunctionCurr Opin Pharmacol20022665065612482726
   PubMed Web of Science ®Google Scholar
• ClouseREDiamantNEMotor function of the esophagusJohnsonLRPhysiology of the Gastrointestinal Tract4th edAcademic Press2006913927
   Google Scholar
• Di StefanoMPapathanasopoulosABlondeauKEffect of buspirone, a 5-HT1A receptor agonist, on esophageal motility in healthy volunteersDis Esophagus201225547047622050410
   PubMed Web of Science ®Google Scholar
• BrowningKNRole of central vagal 5-HT3 receptors in gastrointestinal physiology and pathophysiologyFront Neurosci2015941326578870
   PubMed Web of Science ®Google Scholar
• MarrosuFMaleciACoccoEPulighedduMBarberiniLMarrosuMGVagal nerve stimulation improves cerebellar tremor and dysphagia in multiple sclerosisMult Scler20071391200120217623740
   PubMed Web of Science ®Google Scholar
• KessingBFSmoutAJBenninkRJKraaijpoelNOorsJMBredenoordAJPrucalopride decreases esophageal acid exposure and accelerates gastric emptying in healthy subjectsNeurogastroenterol Motil20142681079108624891067
   PubMed Web of Science ®Google Scholar
• FoxMMenneDStutzBFriedMSchwizerWThe effects of tegaserod on oesophageal function and bolus transport in healthy volunteers: studies using concurrent high-resolution manometry and videofluoroscopyAliment Pharmacol Ther20062471017102716984495
   PubMed Web of Science ®Google Scholar
• LiKLChenJHZhangQHabitual rapid food intake and ineffective esophageal motilityWorld J Gastroenterol201319142270227723599655
   PubMed Web of Science ®Google Scholar
• LundingJANordströmLMHaukelidAOGiljaOHBerstadAHauskenTVagal activation by sham feeding improves gastric motility in functional dyspepsiaNeurogastroenterol Motil200820661862418248581
   PubMed Web of Science ®Google Scholar
• HasegawaYSakagamiJOnoTHoriKZhangMMaedaYCirculatory response and autonomic nervous activity during gum chewingEur J Oral Sci2009117447047319627361
   PubMed Web of Science ®Google Scholar
• KimmelJNCarlsonDAHinchcliffMThe association between systemic sclerosis disease manifestations and esophageal high-resolution manometry parametersNeurogastroenterol Motil Epub2016227
   Web of Science ®Google Scholar
• SinghJCohenSMehendirattaVEffects of scleroderma antibodies and pooled human immunoglobulin on anal sphincter and colonic smooth muscle functionGastroenterology201214351308131822864255
   PubMed Web of Science ®Google Scholar
• CunninghamKMHorowitzMRiddellPSRelations among autonomic nerve dysfunction, oesophageal motility, and gastric emptying in gastro-oesophageal reflux diseaseGut19913212143614401773945
   PubMed Web of Science ®Google Scholar
• PandolfinoJEKahrilasPJAmericanGAAGA technical review on the clinical use of esophageal manometryGastroenterology2005128120922415633138
   PubMed Web of Science ®Google Scholar