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Original Research

Association of IFNL3 rs12979860 polymorphism with HCV-related hepatocellular carcinoma susceptibility in a Chinese population

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Pages 433-439 | Published online: 06 Nov 2019

References

  • Pradat P, Virlogeux V, Trépo E. Epidemiology and elimination of HCV-related liver disease. Viruses. 2018;10(10):pii: E545. doi:10.3390/v10100545
  • Axley P, Ahmed Z, Ravi S, Singal AK. Hepatitis C virus and hepatocellular carcinoma: a narrative review. J Clin Transl Hepatol. 2018;6(1):79–84. doi:10.14218/JCTH.2017.0006729607308
  • Matsuura K, Tanaka Y. Host genetic variations associated with disease progression in chronic hepatitis C virus infection. Hepatol Res. 2018;48(2):127–133. doi:10.1111/hepr.1304229235266
  • Zhang S, Qiao K, Trieu C, et al. Genetic polymorphism of epidermal growth factor rs4444903 influences susceptibility to HCV-related liver cirrhosis and hepatocellular carcinoma in a Chinese Han population. Clin Lab. 2017;63(4):845–850. doi:10.7754/Clin.Lab.2016.16120328397482
  • Prokunina-Olsson L, Muchmore B, Tang W, et al. A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus. Nat Genet. 2013;45(2):164–171. doi:10.1038/ng.252123291588
  • Bibert S, Roger T, Calandra T, et al.; Swiss Hepatitis C Cohort Study. IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction. J Exp Med. 2013;210(6):1109–1116. doi:10.1084/jem.2013001223712427
  • Terczyńska-Dyla E, Bibert S, Duong FH, et al.; Swiss Hepatitis C Cohort Study Group. Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes. Nat Commun. 2014;5:5699. doi:10.1038/ncomms597225534433
  • Ge D, Fellay J, Thompson AJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature. 2009;461(7262):399–401. doi:10.1038/nature0830919684573
  • Thomas DL, Thio CL, Martin MP, et al. Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature. 2009;461(7265):798–801. doi:10.1038/nature0846319759533
  • Tanaka Y, Nishida N, Sugiyama M, et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet. 2009;41(10):1105–1109. doi:10.1038/ng.44919749757
  • Suppiah V, Moldovan M, Ahlenstiel G, et al. IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat Genet. 2009;41(10):1100–1104. doi:10.1038/ng.44719749758
  • Rauch A, Kutalik Z, Descombes P, et al.; Swiss Hepatitis C Cohort Study; Swiss HIV Cohort Study. Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology. 2010;138(4):1338–45, 1345.e1-7. doi:10.1053/j.gastro.2009.12.056
  • Balagopal A, Thomas DL, Thio CL. IL28B and the control of hepatitis C virus infection. Gastroenterology. 2010;139(6):1865–1876. doi:10.1053/j.gastro.2010.10.00420950615
  • Hofmann WP, Zeuzem S. A new standard of care for the treatment of chronic HCV infection. Nat Rev Gastroenterol Hepatol. 2011;8(5):257–264. doi:10.1038/nrgastro.2011.4921468124
  • Hayes CN, Imamura M, Aikata H, Chayama K. Genetics of IL28B and HCV–response to infection and treatment. Nat Rev Gastroenterol Hepatol. 2012;9(7):406–417. doi:10.1038/nrgastro.2012.10122641049
  • Eslam M, George J. Genome-wide association studies and hepatitis C: harvesting the benefits of the genomic revolution. Semin Liver Dis. 2015;35(4):402–420. doi:10.1055/s-0035-156783026676815
  • Eslam M, McLeod D, Kelaeng KS, et al.; International Liver Disease Genetics Consortium (ILDGC). IFN-λ3, not IFN-λ4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis. Nat Genet. 2017;49(5):795–800. doi:10.1038/ng.383628394349
  • Chinnaswamy S. Gene-disease association with human IFNL locus polymorphisms extends beyond hepatitis C virus infections. Genes Immun. 2016;17(5):265–275. doi:10.1038/gene.2016.2427278127
  • Heim MH, Bochud PY, George J. Host - hepatitis C viral interactions: the role of genetics. J Hepatol. 2016;65(1 Suppl):S22–S32. doi:10.1016/j.jhep.2016.07.03727641986
  • Suo GJ, Zhao ZX. Association of the interleukin-28B gene polymorphism with development of hepatitis virus-related hepatocellular carcinoma and liver cirrhosis: a meta-analysis. Genet Mol Res. 2013;12(3):3708–3717. doi:10.4238/2013.September.19.124085431
  • Attallah AM, Omran D, Marie MS, et al. IL-28B rs12979860 polymorphism affect the course of chronic hepatitis and the development of HCC in Egyptian patients with hepatitis C type 4. Br J Biomed Sci. 2018;75(4):157–162. doi:10.1080/09674845.2018.148959929914308
  • Chang KC, Tseng PL, Wu YY, et al. A polymorphism in interferon L3 is an independent risk factor for development of hepatocellular carcinoma after treatment of hepatitis C virus infection. Clin Gastroenterol Hepatol. 2015;13(5):1017–1024. doi:10.1016/j.cgh.2014.10.03525460552
  • Lee MH, Yang HI, Lu SN, et al. Polymorphisms near the IFNL3 gene associated with HCV RNA spontaneous clearance and hepatocellular carcinoma risk. Sci Rep. 2015;5:17030. doi:10.1038/srep1703026602024
  • Ibrahim MK, Salama H, Abd El Rahman M, et al. Three gene signature for predicting the development of hepatocellular carcinoma in chronically infected hepatitis C virus patients. J Interferon Cytokine Res. 2016;36(12):698–705. doi:10.1089/jir.2016.004227726464
  • Chang KC, Ye YH, Wu CK, et al. Risk factors for development of hepatocellular carcinoma in patients with chronic hepatitis C without sustained response to combination therapy. J Formos Med Assoc. 2018;117(11):1011–1018. doi:10.1016/j.jfma.2017.11.00829254684
  • Fabris C, Falleti E, Cussigh A, et al. IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC. J Hepatol. 2011;54(4):716–722. doi:10.1016/j.jhep.2010.07.01921146242
  • El-Awady MK, Mostafa L, Tabll AA, et al. Association of IL28B SNP with progression of Egyptian HCV genotype 4 patients to end stage liver disease. Hepat Mon. 2012;12(4):271–277. doi:10.5812/hepatmon.83522690235
  • Eurich D, Boas-Knoop S, Bahra M, et al. Role of IL28B polymorphism in the development of hepatitis C virus-induced hepatocellular carcinoma, graft fibrosis, and posttransplant antiviral therapy. Transplantation. 2012;93(6):644–649. doi:10.1097/TP.0b013e318244f77422411462
  • Zhang Y, Zhu SL, Chen J, Li LQ. Meta-analysis of associations of interleukin-28B polymorphisms rs8099917 and rs12979860 with development of hepatitis virus-related hepatocellular carcinoma. Onco Targets Ther. 2016;9:3249–3257. doi:10.2147/OTT.S10490427313470
  • Buivydiene A, Liakina V, Kashuba E, et al. Impact of the Uridine-Cytidine kinase like-1 protein and IL28B rs12979860 and rs8099917 SNPs on the development of hepatocellular carcinoma in cirrhotic chronic hepatitis C patients – a pilot study. Medicina (Kaunas). 2018;54(5):pii: E67. doi:10.3390/medicina54050067
  • Agúndez JA, García-Martin E, Maestro ML, et al. Relation of IL28B gene polymorphism with biochemical and histological features in hepatitis C virus-induced liver disease. PLoS One. 2012;7(5):e37998. doi:10.1371/journal.pone.003799822666430
  • Bochud PY, Bibert S, Kutalik Z, et al.; Swiss Hepatitis C Cohort Study Group; ANRS HC EP 26 Genoscan Study Group. IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes. Hepatology. 2012;55(2):384–394. doi:10.1002/hep.2467822180014
  • Joshita S, Umemura T, Katsuyama Y, et al. Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection. Hum Immunol. 2012;73(3):298–300. doi:10.1016/j.humimm.2011.12.02122245236
  • Miura M, Maekawa S, Kadokura M, et al. Analysis of viral amino acids sequences and the IL28B SNP influencing the development of hepatocellular carcinoma in chronic hepatitis C. Hepatol Int. 2012;6(1):386–396. doi:10.1007/s12072-011-9307-622020823
  • Akkiz H, Kuran S, Akgöllü E, Usküdar O, Bekar A, Bayram S. The role of interleukin 28B gene polymorphism in Turkish patients with hepatocellular carcinoma. Ann Hepatol. 2014;13(6):788–795.25332265
  • Zekri AR, Salama H, Medhat E, et al. IL28B rs12979860 gene polymorphism in Egyptian patients with chronic liver disease infected with HCV. Asian Pac J Cancer Prev. 2014;15(17):7213–7218. doi:10.7314/apjcp.2014.15.17.721325227816
  • Qiao K, Trieu C, Huo Z, Du Y, Hou W. Distribution of IL28B rs12979860 and rs8099917 genotypes in patients with chronic hepatitis C virus infection in Tianjin, China. Clin Lab. 2018;64(4):543–550. doi:10.7754/Clin.Lab.2017.17103629739095
  • Wack A, Terczyńska-Dyla E, Hartmann R. Guarding the frontiers: the biology of type III interferons. Nat Immunol. 2015;16(8):802–809. doi:10.1038/ni.321226194286
  • Lasfar A, Zloza A, de la Torre A, Cohen-Solal KA. IFN-λ: a new inducer of local immunity against cancer and infections. Front Immunol. 2016;7:598 eCollection 2016. doi:10.3389/fimmu.2016.0059828018361
  • Lasfar A, Zloza A, Silk AW, Lee LY, Cohen-Solal KA. Interferon lambda: toward a dual role in cancer. J Interferon Cytokine Res. 2019;39(1):22–29. doi:10.1089/jir.2018.004630020822
  • Abushahba W, Balan M, Castaneda I, et al. Antitumor activity of type I and type III interferons in BNL hepatoma model. Cancer Immunol Immunother. 2010;59(7):1059–1071. doi:10.1007/s00262-010-0831-320217081
  • Yan Y, Wang L, He J, et al. Synergy with interferon-lambda 3 and sorafenib suppresses hepatocellular carcinoma proliferation. Biomed Pharmacother. 2017;88:395–402. doi:10.1016/j.biopha.2017.01.07728122304