Advanced search
Publication Cover
Clinical and Experimental Gastroenterology Volume 12, 2019 - Issue
Submit an article Journal homepage
173
Views
2
CrossRef citations to date
0
Altmetric
Original Research

Cholestasis In Infants With Down Syndrome Is Not Due To Extrahepatic Biliary Atresia: A Ten-Year Single Egyptian Centre Experience

Magd A Kotb1 Pediatrics Department, Faculty of Medicine, Kasr Al Ainy, Cairo University, Cairo, EgyptORCID Iconhttps://orcid.org/0000-0001-5928-8684
ORCID Icon,
Iman Draz1 Pediatrics Department, Faculty of Medicine, Kasr Al Ainy, Cairo University, Cairo, Egypt
,
Christine WS Basanti1 Pediatrics Department, Faculty of Medicine, Kasr Al Ainy, Cairo University, Cairo, EgyptORCID Iconhttps://orcid.org/0000-0002-3149-9233
ORCID Icon,
Sally TM El Sorogy2 Pediatrics Department, Public Mounira Hospital, Cairo, Egypt
,
Hesham M Abd Elkader3 Department of Pediatric Surgery, Faculty of Medicine, Ain Shams University, Cairo, EgyptORCID Iconhttps://orcid.org/0000-0002-5612-1157
ORCID Icon,
Haytham Esmat4 Department of Pediatric Surgery, Cairo University, Cairo, Egypt
,
Hend Abd El Baky1 Pediatrics Department, Faculty of Medicine, Kasr Al Ainy, Cairo University, Cairo, Egypt
&
Dalia Sayed Mosallam1 Pediatrics Department, Faculty of Medicine, Kasr Al Ainy, Cairo University, Cairo, EgyptCorrespondence[email protected]
 show all
Pages 401-408 | Published online: 22 Oct 2019

References

  • Stoll C, Dott B, Alembik Y, Roth MP. Associated congenital anomalies among cases with Down syndrome. Eur J Med Genet. 2015;58:674–680. doi:10.1016/j.ejmg.2015.11.00326578241
  • Presson AP, Partyka G, Jensen KM, et al. Current estimate of Down Syndrome population prevalence in the United States. J Pediatr. 2013;163(4):1163–1168. doi:10.1016/j.jpeds.2013.06.01323885965
  • Afifi HH, Aglan MS, Zaki ME, Thomas MM, Tosson AM. Growth charts of Down syndrome in Egypt: a study of 434 children 0–36 months of age. Am J Med Genet A. 2012;158A(11):2647–2655. doi:10.1002/ajmg.a.3546822811286
  • Arnell H, Fischler B. Population-based study of incidence and clinical outcome of neonatal cholestasis in patients with Down syndrome. J Pediatr. 2012;161:899–902. doi:10.1016/j.jpeds.2012.04.03722658787
  • Suchy FJ, Balistreri WF, Heubi JE, Searcy JE, Levin RS. Physiologic cholestasis: elevation of the primary serum bile acid concentrations in normal infants. Gastroenterology. 1981;80:1037–1041. doi:10.1016/0016-5085(81)90078-07202962
  • Halilbasic E, Claudel T, Trauner M. Bile acid transporters and regulatory nuclear receptors in the liver and beyond. J Hepatol. 2013;58:155–168. doi:10.1016/j.jhep.2012.08.00222885388
  • WHO International Standards for Clinical Trial Registries. ISBN 978 92 4 150429 4 (NLM classification: QV 771.4); 2012 Available from: https://apps.who.int/iris/bitstream/handle/10665/76705/9789241504294_eng.pdf;jsessionid=2DA15341BDC67DFDEDE8FC1E1F8B93D5?sequence=1 Accessed 912, 2019. doi:10.1094/PDIS-11-11-0999-PDN
  • WMA DECLARATION OF HELSINKI. WMA declaration of Helsinki - ethical principles for medical research involving human subjects, 64th. WMA general assembly; 2013 Available from https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/ Accessed 912, 2019.
  • Elmagrpy Z, Rayani A, Shah A, Habas E, Aburawi EH. Down syndrome and congenital heart disease: why the regional difference as observed in the Libyan experience? Cardiovasc J Afr. 2011;22:306–309. doi:10.5830/CVJA-2010-07222159317
  • Kim MA, Lee YS, Yee NH, Choi JS, Choi JY, Seo K. Prevalence of congenital heart defects associated with down syndrome in Korea. J Korean Med Sci. 2014;29:1544–1549. doi:10.3346/jkms.2014.29.11.154425408587
  • Morsy MM, Algrigri OO, Salem SS, Abosedera MM, Abutaleb AR, Al-Harbi KM. The spectrum of congenital heart diseases in down syndrome: a retrospective study from Northwest Saudi Arabia. Saudi Med J. 2016;37:767–772. doi:10.15537/smj.2016.7.1453627381537
  • Khoury MJ, Erickson JD. Improved ascertainment of cardiovascular malformations in infants with Down’s syndrome, Atlanta, 1968 through 1989. Implications for the interpretation of increasing rates of cardiovascular malformations in surveillance systems. Am J Epidemiol. 1992;136:1457–1464. doi:10.1093/oxfordjournals.aje.a1164661288275
  • Afifi HH, Abdel Azeem AA, El-Bassyouni HT, Gheith ME, Rizk A, Bateman JB. Distinct ocular expression in infants and children with down syndrome in Cairo. EgyptMyopia Heart Dis JAMA Ophthalmol. 2013;131:1057–1066. doi:10.1001/jamaophthalmol.2013.644
  • Mokhtar MM, Abdel-Fattah M. Major birth defects among infants with Down’s syndrome in Alexandria, Egypt (1995–2000). J Trop Pediatr. 2002;48:247–249. doi:10.1093/tropej/48.4.24712200989
  • Kotb MA, Kotb A. Extrahepatic biliary atresia is an aflatoxin induced cholangiopathy in infants with null GSTM1 genotype with disrupted P53 and GSTPi to mothers heterozygous for GSTM1 polymorphism: damage control is mediated through neutrophil elastase and CD14+ activated monocytes: kotb disease. Med J Cairo Univ. 2015;83:137–145.
  • Rascón Trincado MV, Lorente Toledano F, Villalobos VS. A study of the functions of polymorphonuclear neutrophil in patients with Down’s syndrome. Allergol Immunopathol (Madr). 1988;16:339–345.2976258
  • Novo E, García MI, Lavergne J. Nonspecific immunity in Down syndrome: a study of chemotaxis, phagocytosis, oxidative metabolism, and cell surface marker expression of polymorphonuclear cells. Am J Med Genet. 1993;46:384–391. doi:10.1002/ajmg.13204604087689298
  • Kotb MA. Ursodeoxycholic acid in neonatal hepatitis and infantile paucity of intrahepatic bile ducts: review of a historical cohort. Dig Dis Sci. 2009;54:2231–2241. doi:10.1007/s10620-008-0600-819082720
  • Ram G, Chinen J. Infections and immunodeficiency in Down syndrome. Clin Exp Immunol. 2011;164:9–16. doi:10.1111/j.1365-2249.2011.04335.x21352207
  • Alaama JY, Ahmad MS, Ahmad S, Damanhouri ZA. Altered Metabolism in down Syndrome, Health Problems in down Syndrome. Subrata Dey, IntechOpen; 2015 Available from https://www.intechopen.com/books/health-problems-in-down-syndrome/altered-metabolism-in-down-syndrome. doi:10.5772/60638

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.