Review of Ethnobotanical and Ethnopharmacological Evidence of Some Ethiopian Medicinal Plants Traditionally Used for Peptic Ulcer Disease Treatment

References

• Chan FKL, Graham DY. Prevention of non-steroidal anti-inflammatory drug gastrointestinal complications - review and recommendations based on risk assessment. Aliment Pharmacol Ther. 2004;19(10):1051–1061. doi:10.1111/j.1365-2036.2004.01935.x
   PubMed Web of Science ®Google Scholar
• Debjit B, Chiranjib C, Tripathi KK, Kumar KPS. Recent trends of treatment and medication peptic ulcerative disorder. Int J Pharm Tech Res. 2010;2(1):970–980.
   Google Scholar
• Daniel VT, Wiseman JT, Flahive J, Santry HP. Predictors of mortality in the elderly after open repair for perforated peptic ulcer disease. J Surg Res. 2017;215:108–113. PMID: 28688634. doi:10.1016/j.jss.2017.03.052
   PubMed Web of Science ®Google Scholar
• Abebaw M, Mishra B, Gelayee DA. Evaluation of antiulcer activity of the leaf extract of Osyris quadripartita decne. (Santalaceae) in rats. J Exp Pharmacol. 2017;9:1–11. doi:10.2147/JEP.S125383
   PubMedGoogle Scholar
• Vyawahare NS, Deshmukh VV, Godkari MR, Kagathara VG. Plants with anti-ulcer activity. Pharmacognosy Rev. 2009;3(5):108–115.
   Google Scholar
• Vimala G, Shoba FG. A review on antiulcer activity of few Indian medicinal plants. Int J Microbiol. 2014;2014:1–14. doi:10.1155/2014/519590
   Google Scholar
• Ayantunde AA. Current opinions in bleeding peptic ulcer disease. J Gastrointest Dig Syst. 2014;4:172. doi:10.4172/2161-069X.1000172
   Google Scholar
• Byrge N, Barton RG, Enniss TM, Nirula R. Laparoscopic versus open repair of perforated gastro duodenal ulcer: a National surgical quality improvement program analysis. Am J Surg. 2013;206(6):957–963. PMID: 24112676. doi:10.1016/j.amjsurg.2013.08.014
   PubMed Web of Science ®Google Scholar
• Teka B, Gebre-Selassie S, Abebe T. Sero - prevalence of Helicobacter Pylori in HIV positive patients and HIV negative controls in St. Paul’s general specialized hospital, Addis Ababa, Ethiopia. Sci J Public Health. 2016;4(5):387–393. doi:10.11648/j.sjph.20160405.14
   Google Scholar
• Kumar M, Niyas M, Mani T, Rahiman O, Kumar S. A review on medicinal plants for peptic ulcer. Der Pharmacia Lettre. 2011;3(2):180–186.
   Google Scholar
• Stewart DJ, Ackroyd R. Peptic ulcers and their complications. Surgery. 2011;29(11):568–574.
   Google Scholar
• Lauret M, Pérez I, Rodrigo L. Peptic ulcer disease. Austin J Gastroenterol. 2015;2(5):1055–1063.
   Google Scholar
• Sugano K, Tack J, Kuipers EJ, et al. Kyoto global consensus report on Helicobacter pylori gastritis. Gut. 2015;64(9):1353–1367. PMID: 26187502. doi:10.1136/gutjnl-2015-309252
   PubMed Web of Science ®Google Scholar
• Lau JY, Sung J, Hill C, Henderson C, Howden CW, Metz DC. Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion. 2011;84(2):102–113. PMID: 21494041. doi:10.1159/000323958
   PubMed Web of Science ®Google Scholar
• Rickard J. Surgery for peptic ulcer disease in sub-Saharan Africa: systematic review of published data. J Gastrointest Surg. 2016;20(4):840–850. PMID: 26573850. doi:10.1007/s11605-015-3025-7
   PubMed Web of Science ®Google Scholar
• Toth-Manikowski SM, Grams ME. Proton pump inhibitors and kidney disease-GI upset for the nephrologist? Kidney Int Rep. 2017;2(3):297–301. PMID: 28845467. doi:10.1016/j.ekir.2017.01.005
   PubMed Web of Science ®Google Scholar
• Dashputre NL, Naikwade NS. Evaluation of the anti-ulcer activity of methanolic extract of Abutilon indicum Linn leaves in experimental rats. Int J Pharm Sci Drug Res. 2011;3(2):97–100.
   Google Scholar
• Priyanka V. Some of the medicinal plants with anti-ulcer activity – a review. J Pharm Sci Res. 2015;7(9):772–775.
   Google Scholar
• Yismaw YE, M Abdelwuhab, Ambikar DB, Yismaw AE, Derebe D, Melkam W. Phytochemical and antiulcer activity screening of seed extract of Cordia africana Lam (Boraginaceae) in pyloric ligated rats. Clin Pharmacol. 2020;12:67–73. doi:10.2147/CPAA.S245672
   PubMed Web of Science ®Google Scholar
• Mekonnen AN, Atnafie SA, Wahab Atta A. Evaluation of antiulcer activity of 80% methanol extract and solvent fractions of the root of Croton macrostachyus Hocsht: ex Del. (Euphorbiaceae) in rodents. Evid Based Complement Altern Med. 2020;2020:1–11. doi:10.1155/2020/2809270
   Web of Science ®Google Scholar
• Sisay W, Andargie Y, Molla M, Norahun A. Hydromethanolic crude extract of the leaf of Urtica simensis Hochst. Ex. A. Rich. (Urticaceae) acquires appreciable antiulcer effect: validation for in vivo antiulcer activity. Evid Based Complement Altern Med. 2021;2021:1–12. doi:10.1155/2021/6591070
   Web of Science ®Google Scholar
• Sisay Zewdu W, Jemere Aragaw T. Evaluation of the anti-ulcer activity of hydromethanolic crude extract and solvent fractions of the root of Rumex nepalensis in rats. J Exp Pharmacol. 2020;12:325–337. PMID: 33061674. doi:10.2147/jep.s258586
   PubMedGoogle Scholar
• Melese E, Asres K, Asad M, Engidawork E. Evaluation of the antipeptic ulcer activity of the leaf extract of Plantago lanceolata L. in rodents. Phytother Res. 2011;25(8):1174–1180. PMID: 21298726. doi:10.1002/ptr.3411
   PubMed Web of Science ®Google Scholar
• Kang YM, Komakech R, Karigar CS, Saqib A. Traditional Indian medicine (TIM) and traditional Korean medicine (TKM): a constitutional-based concept and comparison. Integr Med Res. 2017;6(2):105–113. PMID: 28664134. doi:10.1016/j.imr.2016.12.003
   PubMed Web of Science ®Google Scholar
• Gadekar R, Singour PK, Chaurasiya PK, Pawar RS, Patil UK. A potential of some medicinal plants as an antiulcer agents. Pharmacogn Rev. 2010;4(8):136–146. PMID: 22228953. doi:10.4103/0973-7847.70906
   PubMedGoogle Scholar
• Duressa TR. Vascular plant diversity and ethnobotanical study of medicinal and wild edible plants inJibat, Gedo and Chilimo forests, West Shewa zone of Oromia region, Ethiopia MSc thesis. Addis Ababa University; 2016.
   Google Scholar
• Kewessa G, Abebe T, Demessie A. Indigenous knowledge on the use and management of medicinal trees and shrubs in Dale district, Sidama zone, Southern Ethiopia. Ethnobot Res Appl. 2015;14:171–182. doi:10.17348/era.14.0.171-182
   Google Scholar
• Belayneh A, Demissew S, Bussa NF, Bisrat D. Ethno-medicinal and bio-cultural importance of aloes from South and East of the Great Rift Valley floristic regions of Ethiopia. Heliyon. 2020;6(6):e04344. doi:10.1016/j.heliyon.2020.e04344
   PubMed Web of Science ®Google Scholar
• Gebeyehu G, Zemede Asfaw A, Enyew A, Raja N. Ethnobotanical study of traditional medicinal plants and their conservation status in Mecha wereda, West Gojjam zone of Ethiopia. Int J Pharm Sci Health Care Res. 2014;02(03):137–154.
   Google Scholar
• Moravec I, Fernandez E, Vlkova M, Milella L. Ethnobotany of Medicinal Plants of Northern Ethiopia. Boletín Latinoamericano Y Del Caribe De Plantas Medicinales Y Aromáticas. 2014;13(2):126–134.
   Web of Science ®Google Scholar
• Giday M, Asfaw Z, Woldu Z. Ethnomedicinal study of plants used by Sheko ethnic group of Ethiopia. J Ethnopharmacol. 2010;132:75–85. doi:10.1016/j.jep.2010.07.046
   PubMed Web of Science ®Google Scholar
• Chekole G. Ethnobotanical study of medicinal plants used against human ailments in Gubalafto district, Northern Ethiopia. J Ethnobiol Ethnomed. 2017;13:55. doi:10.1186/s13002-017-0182-7
   PubMed Web of Science ®Google Scholar
• Tefera BN. Ethnobotanical study of medicinal plants used by Sidama people of Hawassa Zuria district, Sidama zone, Southern Ethiopia MSc thesis. Hallym University; 2019.
   Google Scholar
• Amsalu N, Bezie Y, Fentahun M, Alemayehu A, Amsalu G. Use and conservation of medicinal plants by indigenous people of Gozamin wereda, East Gojjam zone of Amhara region, Ethiopia: an ethnobotanical approach. Evid Based Complement Altern Med. 2018;2018:1–23. doi:10.1155/2018/2973513
   Web of Science ®Google Scholar
• Beyene ST. An ethnobotanical study of medicinal plants in Wondo Genet natural forest and adjacent kebeles, Sidama zone, SNNP region, Ethiopia MSc thesis. Addis Ababa University; 2011.
   Google Scholar
• Suleman S, Alemu T. A survey on utilization of ethnomedicinal plants in Nekemte town, East Wellega (Oromia), Ethiopia. J Herbs Spices Med Plants. 2012;18(1):34–57. doi:10.1080/10496475.2011.645188
   Google Scholar
• Kassa Z, Asfaw Z, Demissew S. Ethnobotanical study of medicinal plants used by the local people in Tulu Korma and its surrounding areas of Ejere district, Western Shewa zone of Oromia regional state, Ethiopia. J Med Plants Stud. 2016;4(2):24–47.
   Google Scholar
• Yadav RH. Medicinal plants in folk medicine system of Ethiopia. J Poisonous Plant Res. 2013;1(1):007–011.
   Google Scholar
• Abdurhman N. Ethnobotanical study of medicinal plants used by local people in Ofla wereda, Southern zone of Tigray region, Ethiopia MSc thesis. Addis Ababa University; 2010.
   Google Scholar
• Regassa R, Bekele T, Megersa M. Ethnobotonical study of traditional medicinal plants used to treat human ailments by Halaba people, Southern Ethiopia. J Med Plants Stud. 2017;5(4):36–47.
   Google Scholar
• Alebie G, Mehamed A. An ethno-botanical study of medicinal plants in Jigjiga town, capital city of Somali regional state of Ethiopia. Int J Herb Med. 2016;4(6):168–175.
   Google Scholar
• Chekole G, Asfaw Z, Kelbessa E. Ethnobotanical study of medicinal plants in the environs of Tara-gedam and Amba remnant forests of Libo Kemkem district, Northwest Ethiopia. J Ethnobiol Ethnomed. 2015;11:4. doi:10.1186/1746-4269-11-4
   PubMed Web of Science ®Google Scholar
• Bussa NF, Belayneh A. Long-standing herbal medicinal traditions from the prehistoric Harar town and the surroundings, Eastern Ethiopia. J Ayurvedic Herb Med. 2020;6(3):154–172. doi:10.31254/jahm.2020.6311
   Google Scholar
• Birhanu Z. Ethno-botanical survey on medicinal plants used by ethnic groups of Denbia district, North-western Ethiopia. J Nat Remedies. 2011;11(2):119–123. doi:10.18311/jnr/2011/435
   Google Scholar
• Meragiaw M, Asfaw Z, Argaw M. The status of ethnobotanical knowledge of medicinal plants and the impacts of resettlement in Delanta, Northwestern Wello, Northern Ethiopia. Evid Based Complement Altern Med. 2016;2016:1–24. doi:10.1155/2016/5060247
   Web of Science ®Google Scholar
• Flatie T, Gedif T, Asres K, Gebre-Mariam T. Ethnomedical survey of Berta ethnic group Assosa zone, Benishangul-Gumuz regional state, mid-west Ethiopia. J Ethnobiol Ethnomed. 2009;5:14. doi:10.1186/1746-4269-5-14
   PubMed Web of Science ®Google Scholar
• Yineger H. A Study on the ethnobotany of medicinal plants and floristic composition of the dry Afromontane forest at Bale mountains National park, Ethiopia MSc thesis. Addis Ababa University; 2005.
   Google Scholar
• Amsalu N. An ethnobotanical study of medicinal plants in Farta wereda, South Gonder zone of Amhara region, Ethiopia MSc thesis. Addis Ababa University; 2010.
   Google Scholar
• Mekuanent T, Zebene A, Solomon Z. Ethnobotanical study of medicinal plants in Chilga district, Northwestern Ethiopia. J Nat Remedies. 2015;15(2):88–112. doi:10.18311/jnr/2015/476
   Google Scholar
• Enyew A, Asfaw Z, Kelbessa E, Nagappan R. Ethnobotanical study of traditional medicinal plants in and around Fiche district, Central Ethiopia. Curr Res J Biol Sci. 2014;6(4):154–167. doi:10.19026/crjbs.6.5515
   Google Scholar
• Wubetu M, Abula T, Dejenu G. Ethnopharmacologic survey of medicinal plants used to treat human diseases by traditional medical practitioners in Dega Damot district, Amhara, Northwestern Ethiopia. BMC Res Notes. 2017;10:157. doi:10.1186/s13104-017-2482-3
   PubMedGoogle Scholar
• Regassa R. Assessment of indigenous knowledge of medicinal plant practice and mode of service delivery in Hawassa city, Southern Ethiopia. J Med Plant Res. 2013;7(9):517–535. doi:10.5897/JMPR012.1126
   Google Scholar
• Abebe E. Ethnobotanical study on medicinal plants used by local communities in Debark wereda, North Gondar zone, Amhara regional state, Ethiopia MSc thesis. Addis Ababa University; 2011.
   Google Scholar
• Gebrehiwot M. An ethnobotanical study of medicinal plants in Seru wereda, Arsi zone of Oromia region, Ethiopia MSc thesis. Addis Ababa University; 2010.
   Google Scholar
• Wondimu T, Asfaw Z, Kelbessa E. Ethnobotanical study of medicinal plants around ‘Dheeraa’ town, Arsi Zone, Ethiopia. J Ethnopharmacol. 2007;112:152–161. PMID: 17418987. doi:10.1016/j.jep.2007.02.014
   PubMed Web of Science ®Google Scholar
• Gijan M, Dalle G. Ethnobotanical study of medicinal plants in Nagelle Arsi district, West Arsi zone of Oromia, Ethiopia. J Nat Sci Res. 2019;9(13). doi:10.7176/JNSR
   Google Scholar
• Belayneh A, Asfaw Z, Demissew S, Bussa NF. Medicinal plants potential and use by pastoral and agro-pastoral communities in Erer valley of Babile wereda, Eastern Ethiopia. J Ethnobiol Ethnomed. 2012;8:42. PMID: 23082858. doi:10.1186/1746-4269-8-42
   PubMed Web of Science ®Google Scholar
• Adane A. Ethnobotanical study of traditional medicinal plants used by indigenous people of Ankesha district, Awi zone, Amhara regional state, Ethiopia MSc thesis. Addis Ababa University; 2018.
   Google Scholar
• Megersa M, Asfaw Z, Kelbessa E, Beyene A, Woldeab B. An ethnobotanical study of medicinal plants in Wayu Tuka district, East Welega zone of Oromia regional state, West Ethiopia. J Ethnobiol Ethnomed. 2013;9(1):68. PMID: 24295044. doi:10.1186/1746-4269-9-68
   PubMed Web of Science ®Google Scholar
• Maryo M, Nemomissa S, Bekele T. An ethnobotanical study of medicinal plants of the Kembatta ethnic group in Enset-based agricultural landscape of Kembatta Tembaro (KT) zone, Southern Ethiopia. Asian J Plant Sci Res. 2015;5(7):42–61.
   Google Scholar
• Wereta TB. Ethnobotany of medicinal plants in Erob and Gulomahda districts, Eastern zone of Tigray region, Ethiopia MSc thesis. Addis Ababa University; 2015.
   Google Scholar
• Belay H, Wondimu T. Functional food plants in Debre Markos district, East Gojjam, Ethiopia. Asian J Ethnobiol. 2019;2(1):8–21. doi:10.13057/asianjethnobiol/y020102
   Google Scholar
• Atnafu H, Awas T, Alemu S, Wube S. Ethnobotanical study of medicinal plants in Selale mountain ridges, North Shoa, Ethiopia. Biodiversity Int J. 2018;2(6):567‒577. doi:10.15406/bij.2018.02.00114
   Google Scholar
• Yismaw YE, Abdelwuhab M, Ambikar DB, Yismaw AE, Derebe D, Melkam W. Phytochemical and antiulcer activity screening of seed extract of Cordia africana lam (Boraginaceae) in pyloric ligated rats. Clin Pharmacol. 2020;12:67. doi:10.2147/CPAA.S245672
   PubMed Web of Science ®Google Scholar
• Organization For Economic Co-Operation and Development. OECD Guideline for the testing of chemicals: acute oral toxicity-Up-and-down procedure. Available from: http://www.oecdbookshop.org. Accessed May 25, 2020.
   Google Scholar
• Zewdu WS, Aragaw TJ. Evaluation of the anti-ulcer activity of hydromethanolic crude extract and solvent fractions of the root of Rumex nepalensis in Rats. J Exp Pharmacol. 2020;12:325. doi:10.2147/JEP.S258586
   PubMedGoogle Scholar
• Kumar KS, Deenadayalan K. Croton macrostachyus roots used to study phytochemical screening, test for inorganic elements, proximate analysis, qualitative and quantitative characterization of phytoconstituents, antioxidant activities and free radical scavenging activity. Eur J Pharm Med Res. 2017;4(2):517–521.
   Google Scholar