1,059
Views
43
CrossRef citations to date
0
Altmetric
Review

Fecal calprotectin in inflammatory bowel disease

&
Pages 21-29 | Published online: 28 Jan 2016

References

  • National Institute for Health and Clinical ExcellenceFaecal calprotectin diagnostic tests for inflammatory diseases of the bowelNICE diagnostic guideline 11London UK2013
  • FagerholMDaleIAnderssonTA radioimmunoassay for a granulocyte protein as a marker in studies on the turnover of such cellsBull Eur Physiopathol Respir198016Suppl2732827225633
  • HsuKChampaiboonCGuentherBDAnti-infective protective properties of S100 calgranulinsAntiinflamm Antiallergy Agents Med Chem2009829030520523765
  • RosethAAadlandEJahnsenJRaknerudNAssessment of disease activity in ulcerative colitis by fecal calprotectin, a novel granulocyte marker proteinDigestion199758276180
  • RosethASchmidtPFagerholMCorrelation between faecal excretion of indium-111-labelled granulocytes and calprotectin, a granulocyte marker protein, in patients with inflammatory bowel diseaseScand J Gastroenterol199934505410048733
  • RosethAFagerholMAadlandESchjønsbyHAssessment of the neutrophil dominating protein in feces. A methodologic studyScand J Gastroenterol1992277937981411288
  • LassonAStotzerPOÖhmanLIsakssonSSapnaraMStridHThe intra-individual variability of faecal calprotectin: a prospective study in patients with active ulcerative colitisJ Crohns Colitis20159263225008478
  • HusebyeETønHJohneBBiological variability of fecal calprotectin in patients referred for colonoscopy without colonic inflammation or neoplasmAm J Gastroenterol2001962683268711569695
  • CalafatMCabréEManosaMLobatónTMarínLDomènechEHigh within-day variability of fecal calprotectin levels in patients with active ulcerative colitis: What is the best timing for stool sampling?Inflamm Bowel Dis2015211072107625793326
  • NaismithGDSmithLABarrySJA prospective single-centre evaluation of the intra-individual variability of faecal calprotectin in quiescent Crohn’s diseaseAliment Pharmacol Ther20133761362123347334
  • RugtveitJFagerholMKAge-dependent variations in fecal calprotectin concentrations in childrenJ Pediatr Gastroenterol Nutr200234323324 author reply 324–32511964964
  • LabaereDSmismansAVan OlmenAComparison of six different calprotectin assays for the assessment of inflammatory bowel diseaseUnited European Gastroenterol J201423037
  • KokLEliasSGWittemanBJDiagnostic accuracy of point-of-care fecal calprotectin and immunochemical occult blood tests for diagnosis of organic bowel disease in primary care: the Cost-Effectiveness of a Decision Rule for Abdominal Complaints in Primary Care (CEDAR) studyClin Chem20125898999822407858
  • WhiteheadSJFrenchJBrookesMJFordCGamaRBetween-assay variability of faecal calprotectin enzyme-linked immunosorbent assay kitsAnn Clin Biochem201350536123129721
  • TibbleJASigthorssonGFosterRForgacsIBjarnasonIUse of surrogate markers of inflammation and Rome criteria to distinguish organic from nonorganic intestinal diseaseGastroenterol2002123450460
  • GisbertJPMcNichollAGQuestions and answers on the role of faecal calprotectin as a biological marker in inflammatory bowel diseaseDig Liver Dis2009411566618602356
  • Von RoonAKaramountzosLPurkayasthaSDiagnostic precision of fecal calprotectin for inflammatory bowel disease and colorectal malignancyAm J Gastroenterol200710280381317324124
  • Van RheenenPVan de VijvierAFidlerVFaecal calprotectin for screening for patients with suspected inflammatory bowel disease: diagnostic meta-analysisBrit Med J2010341c336920634346
  • DegraeuwePLBeldMPAshornMFaecal calprotectin in suspected paediatric inflammatory bowel diseaseJ Pediatr Gastroenterol Nutr20156033934625373864
  • HendersonPAndersonNWilsonDThe diagnostic accuracy of fecal calprotectin during the investigation of suspected pediatric inflammatory bowel disease: a systematic review and meta-analysisAm J Gastroenterol201410963764523670113
  • BurriEManzMSchroederPDiagnostic yield of endoscopy in patients with abdominal complaints: incremental value of faecal calprotectin on guidelines of appropriatenessBMC Gastroenterology2014145724679065
  • PavlidisPChedgyFJQTibbleJADiagnostic accuracy and clinical application of faecal calprotectin in adult patients presenting with gastrointestinal symptoms in primary careScand J Gastoenterol20134810481054
  • LanghorstJElsenbruchSKoelzerJRuefferAMichalsenADobosGNoninvasive markers in the assessment of intestinal inflammation in inflammatory bowel diseases: performance of fecal lactoferrin, calprotectin, and PMN-elastase, CRP and clinical indicesAm J Gastroenterol200810316216917916108
  • SchoepferAMBeglingerCStraumanAFecal calprotectin correlates more closely with the Simple Endoscopic Score for Crohn’s disease (SES-CD) than CRP, leukocytes and the CDAIAm J Gastroenterol201010516216919755969
  • SchoepferAMBeglingerCStraumanAFecal calprotectin more accurately reflects endoscopic activity of ulcerative colitis than the Lichtiger Index, C-reactive protein, platelets, hemoglobin and blood leukocytesInflamm Bowel Dis20131933234123328771
  • SipponenTSavilahtiEKolhoKLNuutinenHTurunenUFarkkilaMCrohn’s disease activity assessed by fecal calprotectin and lactoferrin: correlation with Crohn’s disease activity index and endoscopic findingsInflamm Bowel Dis200814404618022866
  • LobatónTLópez-GarcíaARodríguez-MorantaFRuizARodríguezLGuardiolaJA new rapid test for fecal calprotectin predicts endoscopic remission and postoperative recurrence in Crohn’s diseaseJ Crohns Colitis20137e641e65123810085
  • SauterBBeglingerCGirardinMMonitoring disease activity and progression in Crohn’s disease. A Swiss perspective on the IBD Ahead ‘Optimised Monitoring’ recommendationsDigestion20148929930925074029
  • SchoepferSMVavrickaSZahnal-StraumannNStraumannABeglingerCMonitoring inflammatory bowel disease activity: clinical activity is judged to be more relevant than endoscopic severity or biomarkersJ Crohns Colitis2012641241822398068
  • RosethAAadlandEGrzybKNormalization of fecal calprotectin: a predictor of mucosal healing in patients with inflammatory bowel diseaseScan J Gastroenterol2004391017102015549460
  • D’HaensGFernanteMVermiereSFecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel diseaseInflamm Bowel Dis2012182218222422344983
  • BurriEBeglingerCvon FeltenSLehmannFSFecal calprotectin and the clinical activity index are both useful to monitor medical treatment in patients with ulcerative colitisDig Dis Sci20156048549125344905
  • SipponenTSavilahtiEKärkkäinenPFecal calprotectin, lactoferrin and endoscopic disease activity in monitoring anti-TNF-alpha therapy for Crohn’s diseaseInflamm Bowel Dis2008141392139818484671
  • De VosMDewitOD’HaensGFast and sharp decline in calprotectin predicts remission by infliximab in anti-TNF naïve patients with ulcerative colitisJ Crohns Colitis2012655756222398050
  • MolanderPAf BjörkesteinCMustonenHFecal calprotectin concentration predicts outcome in inflammatory bowel disease after induction therapy with TNFα blocking agentsInflamm Bowel Dis2012182011201722223566
  • HoGLeeHBrydonGTingTFecal calprotectin predicts the clinical course of acute severe ulcerative colitisAm J Gastroenterol200910467367819262524
  • MolanderPFärkkiläMRistimäkiADoes fecal calprotectin predict short-term relapse after stopping TNFα-blocking agents in inflammatory bowel disease patients in deep remission?J Crohns Colitis20159334025052347
  • TheedeKKiszka-KanowitzMMertz NielsenANordgaard-LassenIThe correlation between fecal calprotectin, simple clinical colitis activity index and biochemical markers in ulcerative colitis during high-dose steroid treatmentScand J Gastroenterol20144941842324495103
  • KolhoKRaivioTLindahlHSavilahtiEFecal calprotectin remains high during glucocorticoids therapy in children with inflammatory bowel diseaseScand J Gastroenterol20064172072516716972
  • KolhoKSipponenTThe long-term outcome of anti-tumour necrosis factor-α therapy related to fecal calprotectin values during induction therapy in paediatric inflammatory bowel diseaseScan J Gastroenterol201449434446
  • ColombelJSandbornWReinischWInfliximab, azothioprine, or combination therapy for Crohn’s diseaseNew Eng J Med20103621383139520393175
  • CostaFMumoloMGCeccarelliLCalprotectin is a stronger predictive marker of relapse in ulcerative colitis than in Crohn’s diseaseGut20055436436815710984
  • TibbleJASigthorssonGBridgerSFagerholMKBjarnasonISurrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel diseaseGastroenterol20001191522
  • SipponenTKolhoKLFaecal calprotectin in children with clinically quiescent inflammatory bowel diseaseScand J Gastroenterol20104587287720377469
  • D’IncàRDal PontEDi LeoVCan calprotectin predict relapse risk in inflammatory bowel diseaseAm J Gastroenterol20081032007101418802997
  • GisbertJPBermejoFPerez-CalleJLFecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapseInflamm Bowel Dis2009151190119819291780
  • DiamantiAColistroFBassoMSClinical role of calprotectin assay in determing histological relapses in children affected by inflammatory bowel diseasesInflamm Bowel Dis2008141229123518398894
  • WalkiewiczDWerlinSLFishDScanlonMHanawayPKugathasanSFecal calprotectin is useful in predicting disease relapse in pediatric inflammatory bowel diseaseInflamm Bowel Dis20081466967318240279
  • KallelLAyadiIMatriSFecal calprotectin is a predictive marker of relapse in Crohn’s disease involving the colon: a prospective studyEur J Gastroenterol Hepatol20102234034519581809
  • Garcia-SanchezVIglesias-FloresEGonzalezRDoes fecal calprotectin predict relapse in patients with Crohn’s disease and ulcerative colitis?J Crohns Colitis2010414415221122498
  • VosMDLouisEJJahnsenJConsecutive fecal calprotectin measurements to predict relapse in patients with ulcerative colitis receiving infliximab maintenance therapyInlamm Bowel Dis2013192112117
  • OrdásIEckmannLTalaminiMBaumgartDCSandbornWJUlcerative colitisLancet20123801606161922914296
  • Van AsscheGDignassAReinischWThe second European evidence-based concensus on the diagnosis and management of Crohn’s disease: Special situationsJ Crohns Colitis201046310121122490
  • LambCAMohiuddinMKGicquelJFaecal calprotectin or lactoferrin can identify postoperative recurrence in Crohn’s diseaseBr J Surg20099666367419384912
  • OrlandoAModestoICastiglioneFThe role of calprotectin in predicting endoscopic post-surgical recurrence in asymptomatic Crohn’s disease: a comparison with ultrasoundEur Rev Med Pharacol Sci2006101722
  • YamamotoTShirakiMBambaTFaecal calprotectin and lactoferrin as markers for monitoring disease activity and predicting clinical recurrence in patients with Crohn’s disease after ileocolonic resection: A prospective pilot studyUnited European Gastroenterol J20131368374
  • WrightEKKammMADe CruzPMeasurement of fecal calprotectin improves monitoring and detection of recurrence of Crohn’s disease after surgeryGastroenterol2015148938947
  • BoschettiGLaidetMMoussataDLevels of fecal calprotectin are associated with the severity of postoperative endoscopic recurrence in asymptomatic patients with Crohn’s diseaseAm J Gastroenterol201511086587225781366
  • YamamotoTThe clinical value of faecal calprotectin and lactoferrin measurement in postoperative Crohn’s diseaseUnited European Gastroenterol20143510
  • ThomasPRihaniHRosethAAssessment of ileal pouch inflammation by single-stool calprotectin assayDis Colon Rectum20004321422010696896
  • JohnsonMMaestranziSDuffyAFaecal calprotectin: a noninvasive diagnostic tool and marker of severity in pouchitisEur J Gastroenterol Hepatol20082017417918301296
  • PakarinenMKoivusaloANatursenJFecal calprotectin mirrors inflammation of the distal ileum and bowel function after restorative proctocolectomy for paediatric-onset ulcerative colitisInflamm Bowel Dis20101648248619685453
  • TibbleJSigthorssonGFosterRSherwoodRFagerholMBjarnasonIFaecal calprotectin and faecal occult blood tests in the diagnosis of colorectal carcinoma and adenomaGut20014940240811511563
  • HoffGGrotmelTThiis-EvensenEBretthauerMGondalGVatnMHTesting for faecal calprotectin (PhiCal) in the Norwegian Colorectal Cancer Prevention trial on flexible sigmoidoscopy screening: comparison with an immunochemical test for occult blood (FlexSure OBT)Gut2004531329133315306594
  • MeucciGD’IncàRMaieronRDiagnostic value of faecal calprotectin in unselected outpatients referred for colonoscopy: A multi centre prospective studyDig Liver Dis20104219119519695969
  • TibbleJASigthorssonGFosterRHigh prevalence of NSAID enteropathy as shown by a simple faecal testGut19994536236610446103
  • MaidenLCapsule endoscopic diagnosis of nonsteroidal anti-inflammatory drug-induced enteropathyJ Gastroenterol200944Suppl 19647119148796
  • ShastriYMBergisDPovseNProspective multicentre study evaluating fecal calprotectin in adult acute bacterial diarrhoeaSm J Med200812110991106
  • NielsenHLEngbergJEjlertsenTNielsenHEvaluation of fecal calprotectin in Campylobacter concisus and Camplylobacter jejuni/coli gastroenteritisScand J Gastroenterol20134863363523448294
  • SykoraJSialaKHumiMVarvarovskáJSchwarzJPomahacováREvaluation of faecal calprotectin as a valuable non-invasive marker in distinguishing gut pathogens in young children with acute gastroenteritisActa Paediatr2010991389139520412103
  • ChenCCHuangJLChangCJKongMSFecal calprotectin as a correlative marker in clinical severity of infectious diarrhoea and usefulness in evaluating bacterial or viral pathogens in childrenJ Pediatr Gastroenterol Nutr20125554154722699836
  • TursiABrandimarteGEliseiWGiorgettiGMInchingoloCDAielloFFaecal calprotectin in colonic diverticulitis: a case-control studyInt J Colorectal Dis200924495518941760
  • TursiABiomarkers in diverticular disease of the colonDig Dis201230121822572679
  • SherwoodRAFaecal markers of gastrointestinal inflammationJ Clin Path20126598198522813730
  • LehmannFSBurriEBeglingerCThe role and utility of faecal markers in inflammatory bowel diseaseTher Adv Gastroenterol201582336
  • YangZClarkNParkKTEffectiveness and cost-effectiveness of measurement of fecal calprotectin in the diagnosis of inflammatory bowel diseaseClin Gastroenterol Hepatol20141225326223883663