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Review

Diagnosis and management of microscopic colitis: current perspectives

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Pages 273-284 | Published online: 21 Aug 2014

References

  • NyhlinNBohrJErikssonSTyskCSystematic review: microscopic colitisAliment Pharmacol Ther200623111525153416696800
  • PardiDSKellyCPMicroscopic colitisGastroenterology201114041155116521303675
  • MünchAAustDBohrJMicroscopic colitis: current status, present and future challenges: statements of the European Microscopic Colitis GroupJ Crohns Colitis20126993294522704658
  • LindströmCG‘Collagenous colitis’ with watery diarrhoea – a new entity?Pathol Eur19761118789934705
  • FreemanHWeinsteinWMShnitkaTWenselRHSartorVEWatery diarrhea syndrome associated with a lesion of the colonic basement membrane-lamina propria interfaceAnn Royal Coll Phys Surg Can19769A45
  • LazenbyAJYardleyJHGiardielloFMJessurunJBaylessTMLymphocytic (“microscopic”) colitis: a comparative histopathologic study with particular reference to collagenous colitisHum Pathol198920118282912870
  • FekihMBen HrizFSassiAMatriSFilaliABoubakerJMicroscopic colitis. A 20 cases seriesTunis Med2006847403406 French17039729
  • GargPKSinghJDhaliGKMathurMSharmaMPMicroscopic colitis is a cause of large bowel diarrhea in Northern IndiaJ Clin Gastroenterol199622111158776087
  • Rubio-TapiaAMartinez-SalgadoJGarcía-LeivaJMartinez-BenítezBUribeMMicroscopic colitides: a single center experience in MexicoInt J Colorectal Dis20072291031103617242940
  • ParkYSBaekDHKimWHClinical characteristics of microscopic colitis in Korea: prospective multicenter study by KASIDGut Liver20115218118621814598
  • BohrJTyskCErikssonSJärnerotGCollagenous colitis in Örebro, Sweden, an epidemiological study 1984–1993Gut19953733943977590436
  • OlesenMErikssonSBohrJJarnerotGTyskCMicroscopic colitis: a common diarrhoeal disease. An epidemiological study in Örebro, Sweden, 1993–1998Gut200453334635014960513
  • WickbomABohrJErikssonSUdumyanRNyhlinNTyskCStable incidence of collagenous colitis and lymphocytic colitis in Örebro, Sweden, 1999–2008: a continuous epidemiological studyInflamm Bowel Dis201319112387239323945183
  • PardiDSLoftusEVJrSmyrkTCThe epidemiology of microscopic colitis: a population based study in Olmsted County, MinnesotaGut200756450450817135309
  • GentileNMKhannaSLoftusEVJrThe epidemiology of microscopic colitis in Olmsted County from 2002 to 2010: a population-based studyClin Gastroenterol Hepatol201412583884224120840
  • BenchimolEIKirschRVieroSGriffithsAMCollagenous colitis and eosinophilic gastritis in a 4-year old girl: a case report and review of the literatureActa Paediatr20079691365136717718794
  • CamareroCLeonFColinoECollagenous colitis in children: clinicopathologic, microbiologic, and immunologic featuresJ Pediatr Gastroenterol Nutr200337450851314508225
  • OlesenMErikssonSBohrJJarnerotGTyskCLymphocytic colitis: a retrospective clinical study of 199 Swedish patientsGut200453453654115016748
  • WilliamsJJKaplanGGMakhijaSMicroscopic colitis-defining incidence rates and risk factors: a population-based studyClin Gastroenterol Hepatol200861354018166476
  • StewartMAndrewsCNUrbanskiSBeckPLStorrMThe association of coeliac disease and microscopic colitis: a large population-based studyAliment Pharmacol Ther201133121340134921517923
  • Fernández-BañaresFSalasAFornéMEsteveMEspinósJViverJMIncidence of collagenous and lymphocytic colitis: a 5-year population-based studyAm J Gastroenterol199994241842310022639
  • Fernández-BañaresFSalasAEsteveMEvolution of the incidence of collagenous colitis and lymphocytic colitis in Terrassa, Spain: a population-based studyInflamm Bowel Dis20111741015102020878755
  • AgnarsdottirMGunnlaugssonOOrvarKBCollagenous and lymphocytic colitis in IcelandDig Dis Sci20024751122112812018911
  • BjørnbakCEngelPJNielsenPLMunckLKMicroscopic colitis: clinical findings, topography and persistence of histopathological subgroupsAliment Pharmacol Ther201134101225123421967618
  • VigrenLOlesenMBenoniCSjöbergKAn epidemiological study of collagenous colitis in southern Sweden from 2001–2010World J Gastroenterol201218222821282622719191
  • GuagnozziDLucendoAJAngueira-LapeñaTGonzález-CastilloSTenias BurilloJMPrevalence and incidence of microscopic colitis in patients with diarrhoea of unknown aetiology in a region in central SpainDig Liver Dis201244538438822265684
  • ThörnMSjöbergDEkbomAMicroscopic colitis in Uppsala health region, a population-based prospective study 2005–2009Scand J Gastroenterol201348782583023721118
  • TyskCWickbomANyhlinNErikssonSBohrJRecent advances in diagnosis and treatment of microscopic colitisAnn Gastroenterol201124425326224713787
  • BohrJTyskCErikssonSAbrahamssonHJärnerotGCollagenous colitis: a retrospective study of clinical presentation and treatment in 163 patientsGut199639968468519038667
  • BohrJLarssonLGErikssonSJärnerotGTyskCColonic perforation in collagenous colitis: an unusual complicationEur J Gastroenterol Hepatol200517112112415647652
  • AllendeDSTaylorSLBronnerMPColonic perforation as a complication of collagenous colitis in a series of 12 patientsAm J Gastroenterol2008103102598260418702648
  • AbboudRPardiDSTremaineWJKammerPPSandbornWJLoftusEVJrSymptomatic overlap between microscopic colitis and irritable bowel syndrome: a prospective studyInflamm Bowel Dis201319355055323380937
  • LimsuiDPardiDSCamilleriMSymptomatic overlap between irritable bowel syndrome and microscopic colitisInflamm Bowel Dis200713217518117206699
  • NyhlinNWickbomAMontgomerySMTyskCBohrJLong-term symptom burden and health-related quality of life in patients with collagenous and lymphocytic colitis; a case-control studyAliment Pharmacol Ther201439996397224612051
  • HalpinSJFordACPrevalence of symptoms meeting criteria for irritable bowel syndrome in inflammatory bowel disease: systematic review and meta-analysisAm J Gastroenterol2012107101474148222929759
  • Fernandez-BañaresFEsteveMSalasABile acid malabsorption in microscopic colitis and in previously unexplained functional chronic diarrheaDig Dis Sci200146102231223811680602
  • UngKAGillbergRKilanderAAbrahamssonHRole of bile acids and bile acid binding agents in patients with collagenous colitisGut200046217017510644309
  • UngKAKilanderAWillenRAbrahamssonHRole of bile acids in lymphocytic colitisHepatogastroenterology2002494443243711995467
  • WildtSNordgaard-LassenIBendtsenFRumessenJJMetabolic and inflammatory faecal markers in collagenous colitisEur J Gastroenterol Hepatol200719756757417556903
  • WagnerMLampinenMSangfeltPAgnarsdottirMCarlsonMBudesonide treatment of patients with collagenous colitis restores normal eosinophil and T-cell activity in the colonInflamm Bowel Dis20101671118112620027654
  • WagnerMPetersonCGStoltIFecal eosinophil cationic protein as a marker of active disease and treatment outcome in collagenous colitis: a pilot studyScand J Gastroenterol2011467–884985421557718
  • WagnerMStridsbergMPetersonCGSangfeltPLampinenMCarlsonMIncreased fecal levels of chromogranin A, chromogranin B, and secretoneurin in collagenous colitisInflammation201336485586123423580
  • Cruz-CorreaMMilliganFGiardielloFMCollagenous colitis with mucosal tears on endoscopic insufflation: a unique presentationGut200251460012235088
  • ShermanAAckertJJRajapaksaRWestABOweityTFractured colon: an endoscopically distinctive lesion associated with colonic perforation following colonoscopy in patients with collagenous colitisJ Clin Gastroenterol200438434134515087693
  • WickbomALindqvistMBohrJColonic mucosal tears in collagenous colitisScand J Gastroenterol200641672672916716973
  • KiesslichRHoffmanAGoetzMIn vivo diagnosis of collagenous colitis by confocal endomicroscopyGut200655459159216531549
  • MeiningASchwendySBeckerVSchmidRMPrinzCIn vivo histopathology of lymphocytic colitisGastrointest Endosc200766239839917521648
  • ZambelliAVillanacciVBuscariniEBassottiGAlbarelloLCollagenous colitis: a case series with confocal laser microscopy and histology correlationEndoscopy200840760660818609454
  • MagroFLangnerCDriessenAEuropean consensus on the histopathology of inflammatory bowel diseaseJ Crohns Colitis201371082785123870728
  • MünchALangnerCMicroscopic colitis: clinical and pathologic perspectivesClin Gastroenterol Hepatol Epub172014
  • AustDMünchAOlesenMTopographical distribution of collagenous colitis – a pooled histological analysis of 2 European prospective multicenter trialsGastroenterology2013144Suppl 1S421
  • WarrenBFEdwardsCMTravisSP‘Microscopic colitis’: classification and terminologyHistopathology200240437437611943023
  • GoldsteinNSBhanotPPaucicellular and asymptomatic lymphocytic colitis: expanding the clinicopathologic spectrum of lymphocytic colitisAm J Clin Pathol2004122340541115362371
  • Fernández-BañaresFCasalotsJSalasAPaucicellular lymphocytic colitis: is it a minor form of lymphocytic colitis? A clinical pathological and immunological studyAm J Gastroenterol200910451189119819352342
  • LibbrechtLCroesREctorsNStaelsFGeboesKMicroscopic colitis with giant cellsHistopathology200240433533811943017
  • SandmeierDBouzoureneHMicroscopic colitis with giant cells: a rare new histopathologic subtype?Int J Surg Pathol2004121454814765272
  • YuanSReyesVBronnerMPPseudomembranous collagenous colitisAm J Surg Pathol200327101375137914508399
  • RubioCALindholmJCryptal lymphocytic coloproctitis: a new phenotype of lymphocytic colitis?J Clin Pathol200255213814011865010
  • SaurineTJBrewerJMEcksteinRPMicroscopic colitis with granulomatous inflammationHistopathology2004451828615228447
  • ChangFDeereHVuCAtypical forms of microscopic colitis: morphological features and review of the literatureAdv Anat Pathol200512420321116096382
  • AbdoAAZetlerPJHalparinLSFamilial microscopic colitisCan J Gastroenterol200115534134311381303
  • FreemanHJFamilial occurrence of lymphocytic colitisCan J Gastroenterol2001151175776011727006
  • JärnerotGHertervigEGrännöCFamilial occurrence of microscopic colitis: a report on five familiesScand J Gastroenterol200136995996211521987
  • van TilburgAJLamHGSeldenrijkCAFamilial occurrence of collagenous colitis. A report of two familiesJ Clin Gastroenterol19901232792852362097
  • FineKDDoKSchulteKHigh prevalence of celiac sprue-like HLA-DQ genes and enteropathy in patients with the microscopic colitis syndromeAm J Gastroenterol20009581974198210950045
  • KoskelaRMKarttunenTJNiemeläSELehtolaJKIlonenJKarttunenRAHuman leucocyte antigen and TNFα polymorphism association in microscopic colitisEur J Gastroenterol Hepatol200820427628218334870
  • MadischAHellmigSSchreiberSBethkeBStolteMMiehlkeSAllelic variation of the matrix metalloproteinase-9 gene is associated with collagenous colitisInflamm Bowel Dis201117112295229821305678
  • MadischAHellmigSSchreiberSBethkeBStolteMMiehlkeSNOD2/CARD15 gene polymorphisms are not associated with collagenous colitisInt J Colorectal Dis200722442542816804670
  • AbrahamCChoJHInflammatory bowel diseaseN Engl J Med2009361212066207819923578
  • XavierRJPodolskyDKUnravelling the pathogenesis of inflammatory bowel diseaseNature2007448715242743417653185
  • ArmesJGeeDCMacraeFASchroederWBhathalPSCollagenous colitis: jejunal and colorectal pathologyJ Clin Pathol19924597847871401208
  • MosnierJFLarvolLBargeJLymphocytic and collagenous colitis: an immunohistochemical studyAm J Gastroenterol19969147097138677934
  • GöranzonCKumawatAKHultgren-HörnqvistEImmunohistochemical characterization of lymphocytes in microscopic colitisJ Crohns Colitis2013710e434e44223523417
  • KumawatAKStridHElgbrattKTyskCBohrJHultgren HörnquistEMicroscopic colitis patients have increased proportions of Ki67(+) proliferating and CD45RO(+) active/memory CD8(+) and CD4(+)8(+) mucosal T cellsJ Crohns Colitis20137969470522995775
  • ElgbrattKKurlbergGHahn-ZohricMHörnquistEHRapid migration of thymic emigrants to the colonic mucosa in ulcerative colitis patientsClin Exp Immunol2010162232533620840654
  • KumawatAKElgbrattKTyskCBohrJHörnquistEHReduced T cell receptor excision circle levels in the colonic mucosa of microscopic colitis patients indicate local proliferation rather than homing of peripheral lymphocytes to the inflamed mucosaBiomed Res Int2013201340863823956982
  • JärnerotGTyskCBohrJErikssonSCollagenous colitis and fecal stream diversionGastroenterology199510924494557615194
  • KumawatAKStridHTyskCBohrJHörnquistEHMicroscopic colitis patients demonstrate a mixed Th17/Tc17 and Th1/Tc1 mucosal cytokine profileMol Immunol2013553–435536423566938
  • TagkalidisPPGibsonPRBhathalPSMicroscopic colitis demonstrates a T helper cell type 1 mucosal cytokine profileJ Clin Pathol200760438238716775121
  • GünaltaySNyhlinNKumawatAKDifferential expression of IL-1/TLR signaling regulators in microscopic and ulcerative colitisWorld J Gastroenterol2014
  • TahaYCarlsonMThornMLoofLRaabYEvidence of local eosinophil activation and altered mucosal permeability in collagenous colitisDig Dis Sci200146488889711330429
  • TahaYRaabYLarssonAMucosal secretion and expression of basic fibroblast growth factor in patients with collagenous colitisAm J Gastroenterol20039892011201714499780
  • TahaYRaabYLarssonAVascular endothelial growth factor (VEGF) – a possible mediator of inflammation and mucosal permeability in patients with collagenous colitisDig Dis Sci200449110911514992444
  • GrigaTTrommASchmiegelWPfistererOMüllerKMBraschFCollagenous colitis: implications for the role of vascular endothelial growth factor in repair mechanismsEur J Gastroenterol Hepatol200416439740215028972
  • SalasAFernández-BañaresFCasalotsJSubepithelial myofibroblasts and tenascin expression in microscopic colitisHistopathology2003431485412823712
  • MedinaCRadomskiMWRole of matrix metalloproteinases in intestinal inflammationJ Pharmacol Exp Ther2006318393393816644899
  • GüntherUSchuppanDBauerMFibrogenesis and fibrolysis in collagenous colitis. Patterns of procollagen types I and IV, matrix-metalloproteinase-1 and -13, and TIMP-1 gene expressionAm J Pathol1999155249350310433942
  • LundbergJOHerulfMOlesenMIncreased nitric oxide production in collagenous and lymphocytic colitisEur J Clin Invest199727108698719373768
  • OlesenMMiddelveldRBohrJLuminal nitric oxide and epithelial expression of inducible and endothelial nitric oxide synthase in collagenous and lymphocytic colitisScand J Gastroenterol2003381667212608467
  • PernerAAndresenLNormarkMExpression of nitric oxide synthases and effects of L-arginine and L-NMMA on nitric oxide production and fluid transport in collagenous colitisGut200149338739411511561
  • PernerANordgaardIMatzenPRask-MadsenJColonic production of nitric oxide gas in ulcerative colitis, collagenous colitis and uninflamed bowelScand J Gastroenterol200237218318811843055
  • BonderupOKHansenJBMadsenPVestergaardVFallingborgJTeglbjaergPSBudesonide treatment and expression of inducible nitric oxide synthase mRNA in colonic mucosa in collagenous colitisEur J Gastroenterol Hepatol200618101095109916957516
  • MünchASöderholmJDWallonCÖstAOlaisonGStrömMDynamics of mucosal permeability and inflammation in collagenous colitis before, during, and after loop ileostomyGut20055481126112816009686
  • MünchASöderholmJDÖstAStrömMIncreased transmucosal uptake of E. coli K12 in collagenous colitis persists after budesonide treatmentAm J Gastroenterol2009104367968519209166
  • BohrJNordfelthRJärnerotGTyskCYersinia species in collagenous colitis: a serologic studyScand J Gastroenterol200237671171412126251
  • ErimTAlazmiWMO’LoughlinCJBarkinJSCollagenous colitis associated with Clostridium difficile: a cause effect?Dig Dis Sci20034871374137512870798
  • MäkinenMNiemeläSLehtolaJKarttunenTJCollagenous colitis and Yersinia enterocolitica infectionDig Dis Sci1998436134113469635629
  • PerkGAckermanZCohenPEliakimRLymphocytic colitis: a clue to an infectious triggerScand J Gastroenterol199934111011210048742
  • LaSalaPRChodoshABVecchioJASchnedLMBlaszykHSeasonal pattern of onset in lymphocytic colitisJ Clin Gastroenterol2005391089189316208113
  • VigrenLTyskCStrömMCeliac disease and other autoimmune diseases in patients with collagenous colitisScand J Gastroenterol201348894495023800241
  • WangYLiuXPZhaoZBChenJHYuCGExpression of CD4+ forkhead box P3 (FOXP3)+ regulatory T cells in inflammatory bowel diseaseJ Dig Dis201112428629421791023
  • GötlindYYRaghavanSBlandPWHörnquistEHCD4+FoxP3+ regulatory T cells from Gαi2−/− mice are functionally active in vitro, but do not prevent colitisPLoS One201169e2507321966415
  • Fernández-BañaresFde SousaMRSalasAEpidemiological risk factors in microscopic colitis: a prospective case-control studyInflamm Bowel Dis201319241141723344243
  • VigrenLSjöbergKBenoniCIs smoking a risk factor for collagenous colitis?Scand J Gastroenterol201146111334133921854096
  • YenEFPokhrelBDuHCurrent and past cigarette smoking significantly increase risk for microscopic colitisInflamm Bowel Dis201218101835184122147506
  • Fernández-BañaresFde SousaMRSalasAImpact of current smoking on the clinical course of microscopic colitisInflamm Bowel Dis20131971470147623552765
  • BeaugerieLPardiDSReview article: drug-induced microscopic colitis – proposal for a scoring system and review of the literatureAliment Pharmacol Ther200522427728416097993
  • MiehlkeSMadischAKupcinskasLBudesonide is more effective than mesalamine or placebo in short-term treatment of collagenous colitisGastroenterology201414651222123024440672
  • ChandeNMcDonaldJWMacdonaldJKInterventions for treating lymphocytic colitisCochrane Database Syst Rev20082CD00609618425936
  • ChandeNMcDonaldJWMacdonaldJKInterventions for treating collagenous colitisCochrane Database Syst Rev20082CD00357518425892
  • BaertFSchmitAD’HaensGBudesonide in collagenous colitis: a double-blind placebo-controlled trial with histologic follow-upGastroenterology20021221202511781276
  • BonderupOKHansenJBBirket-SmithLVestergaardVTeglbjaergPSFallingborgJBudesonide treatment of collagenous colitis: a randomised, double blind, placebo controlled trial with morphometric analysisGut200352224825112524408
  • MiehlkeSHeymerPBethkeBBudesonide treatment for collagenous colitis: a randomized, double-blind, placebo-controlled, multicenter trialGastroenterology2002123497898412360457
  • MiehlkeSMadischAKarimiDBudesonide is effective in treating lymphocytic colitis: a randomized double-blind placebo-controlled studyGastroenterology200913672092210019303012
  • BonderupOKHansenJBTeglbjaergPSChristensenLAFallingborgJFLong-term budesonide treatment of collagenous colitis: a randomised, double-blind, placebo-controlled trialGut2009581687218669576
  • MiehlkeSMadischABethkeBOral budesonide for maintenance treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trialGastroenterology200813551510151618926826
  • MiehlkeSHansenJBMadischARisk factors for symptom relapse in collagenous colitis after withdrawal of short-term budesonide therapyInflamm Bowel Dis201319132763276724216688
  • MünchABohrJMiehlkeSLow-dose budesonide is an effective maintenance therapy in collagenous colitis: results from the randomised, placebo-controlled BUC-63/COC-trialUnited European Gastroenterol J201311SA35
  • MunckLKKjeldsenJPhilipsenEFischer HansenBIncomplete remission with short-term prednisolone treatment in collagenous colitis: a randomized studyScand J Gastroenterol200338660661012825868
  • GentileNMAbdallaAAKhannaSOutcomes of patients with microscopic colitis treated with corticosteroids: a population-based studyAm J Gastroenterol2013108225625923295275
  • CalabreseCFabbriAAreniAZahlaneDScialpiCDi FeboGMesalazine with or without cholestyramine in the treatment of microscopic colitis: randomized controlled trialJ Gastroenterol Hepatol200722680981417565633
  • WildtSMunckLKVinter-JensenLProbiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with Lactobacillus acidophilus and Bifidobacterium animalis subsp. lactisInflamm Bowel Dis200612539540116670529
  • MadischAMiehlkeSEicheleOBoswellia serrata extract for the treatment of collagenous colitis. A double-blind, randomized, placebo-controlled, multicenter trialInt J Colorectal Dis200722121445145117764013
  • PardiDSLoftusEVJrTremaineWJSandbornWJTreatment of refractory microscopic colitis with azathioprine and 6-mercaptopurineGastroenterology200112061483148411313319
  • MünchAFernández-BañaresFMunckLKAzathioprine and mercaptopurine in the management of patients with chronic, active microscopic colitisAliment Pharmacol Ther201337879579823432370
  • RiddellJHillmanLChiragakisLClarkeACollagenous colitis: oral low-dose methotrexate for patients with difficult symptoms: long-term outcomesJ Gastroenterol Hepatol200722101589159317845686
  • MünchABohrJVigrenLTyskCStrömMLack of effect of methotrexate in budesonide-refractory collagenous colitisClin Exp Gastroenterol2013614915224039441
  • AramGBaylessTMChenZMMontgomeryEADonowitzMGiardielloFMRefractory lymphocytic enterocolitis and tumor necrosis factor antagonist therapyClin Gastroenterol Hepatol20108439139420036760
  • EsteveMMahadevanUSainzERodriguezESalasAFernández-BañaresFEfficacy of anti-TNF therapies in refractory severe microscopic colitisJ Crohns Colitis20115661261822115383
  • MünchAIgnatovaSStrömMAdalimumab in budesonide and methotrexate refractory collagenous colitisScand J Gastroenterol2012471596322149977
  • PolaSFahmyMEvansETippsASandbornWJSuccessful use of infliximab in the treatment of corticosteroid dependent collagenous colitisAm J Gastroenterol2013108585785823644970
  • FineKDOgunjiFLeeELafonGTanziMRandomized, double blind, placebo-controlled trial of bismuth subsalicylate for microscopic colitisGastroenterology19991164A880
  • VargheseLGalandiukSTremaineWJBurgartLJLymphocytic colitis treated with proctocolectomy and ileal J-pouch-anal anastomosis: report of a caseDis Colon Rectum200245112312611786777
  • HjortswangHTyskCBohrJHealth-related quality of life is impaired in active collagenous colitisDig Liver Dis201143210210920638918
  • HjortswangHTyskCBohrJDefining clinical criteria for clinical remission and disease activity in collagenous colitisInflamm Bowel Dis200915121875188119504614
  • MadischAHeymerPVossCOral budesonide therapy improves quality of life in patients with collagenous colitisInt J Colorectal Dis200520431231615549326