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Methodology

The Cost-Effectiveness of Universal Varicella Vaccination in Italy: A Model-Based Assessment of Vaccination Strategies

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Pages 273-283 | Published online: 08 Jun 2020

References

  • Heininger U, Seward JF. Varicella. Lancet. 2006;368(9544):1365–1376. doi:10.1016/S0140-6736(06)69561-5
  • Sadzot-Delvaux C, Rentier B, Wutzler P, et al. Varicella vaccination in Japan, South Korea, and Europe. J Infect Dis. 2008;197(2):185–190. doi:10.1086/522163
  • Bardach A, Cafferata ML, Klein K, Cormick G, Gibbons L, Ruvinsky S. Incidence and use of resources for chickenpox and herpes zoster in Latin America and the Caribbean–a systematic review and meta-analysis. Pediatr Infect Dis J. 2012;31(12):1263–1268. doi:10.1097/INF.0b013e31826ff3a5
  • Czumbel I, Quinten C, Lopalco P, et al. Management and control of communicable diseases in schools and other child care settings: systematic review on the incubation period and period of infectiousness. BMC Infect Dis. 2018;18(1):199. doi:10.1186/s12879-018-3095-8
  • Gnann J. Varicella-zoster virus: atypical presentations and unusual complications. J Infect Dis. 2002;186(1):S91–S98.
  • Dunkle LM, Arvin AM, Whitley RJ, et al. A controlled trial of acyclovir for chickenpox in normal children. N Engl J Med. 1991;325(22):1539–1544. doi:10.1056/NEJM199111283252203
  • European Centre for Disease Prevention and Control. Guidance for Varicella Vaccination in the European Union; 2015.
  • Marchetti M, Kühnel UM, Colombo GL, Esposito S, Principi N. Cost-effectiveness of adjuvanted influenza vaccination of healthy children 6 to 60 months of age. Hum Vaccin. 2007;3(1):14–22. doi:10.4161/hv.3.1.3657
  • Choo PW, Donahue JG, Manson JE, Platt R. The epidemiology of varicella and its complications. J Infect Dis. 1995;172(3):706–712. doi:10.1093/infdis/172.3.706
  • Krugman S, Goodrich CH, Ward R. Primary varicella pneumonia. N Engl J Med. 1957;257(18):843–848. doi:10.1056/NEJM195710312571801
  • Gogos CA, Bassaris HP, Vagenakis AG. Varicella pneumonia in adults. A review of pulmonary manifestations, risk factors and treatment. Respiration. 1992;59(6):339–343. doi:10.1159/000196084
  • Preblud SR. Varicella: complications and costs. Pediatrics. 1986;78:4.
  • Galil K, Brown C, Lin F, Seward J. Hospitalizations for varicella in the United States, 1988 to 1999. Pediatr Infect Dis J. 2002;21(10):931–934. doi:10.1097/00006454-200210000-00009
  • Fangjun Z, Harpaz R, Jumaan A, et al. Impact of Varicella Vaccination on Health Care Utilization. JAMA. 2005;294(5):7.
  • Robert Koch-Institut. Empfehlungen der Ständigen Impfkommission (STIKO) Robert Koch-Institut. Epidemiol Bull. 2003;2003.
  • Davis MM, Patel MS, Gebremariam A. Decline in varicella-related hospitalizations and expenditures for children and adults after introduction of varicella vaccine in the United States. Pediatrics. 2004;114(3). doi:10.1542/peds.2004-0012
  • Nguyen HQ, Jumaan AO, Seward JF. Decline in mortality due to varicella after implementation of varicella vaccination in the United States. N Engl J Med. 2005;352(5):450–458. doi:10.1056/NEJMoa042271
  • Lopez A, Zhang J, Brown C, Bialek S. Varicella-related hospitalizations in the United States, 2000–2006: the 1-dose varicella vaccination era. Pediatrics. 2011;127(2):2. doi:10.1542/peds.2010-0962
  • Marin M, Zhang JX, Seward JF. Near elimination of varicella deaths in the US after implementation of the vaccination program. Pediatrics. 2011;128(2):214–220. doi:10.1542/peds.2010-3385
  • Lieu TA, Cochi SL, Black SB. Cost-effectiveness of a routine varicella vaccination program for US children. JAMA. 1994;271(5):375–381. doi:10.1001/jama.1994.03510290057037
  • Kwong JC, Tanuseputro P, Zagorski B, et al. Impact of varicella vaccination on health care outcomes in Ontario, Canada: effect of a publicly funded program? Vaccine. 2008;26(47):6006–6012. doi:10.1016/j.vaccine.2008.08.016
  • Amodio E, Tramuto F, Cracchiolo M, et al. The impact of ten years of infant universal varicella vaccination in Sicily, Italy (2003-2012). Hum Vaccin Immunother. 2015;11(1):236–239. doi:10.4161/hv.36157
  • Pezzotti P, Bellino S, Prestinaci F, et al. The impact of immunization programs on 10 vaccine preventable diseases in Italy: 1900–2015. Vaccine. 2018;36(11):1435–1443. doi:10.1016/j.vaccine.2018.01.065
  • Ministro della Salute. Le novità del decreto legge sui vaccini. 2017.
  • World Health Organization. Principles and Considerations for Adding a Vaccine to a National Immunization Programme from Decision to Implementation and Monitoring; 2014.
  • Wolfson LJ, Daniels VJ, Pillsbury M, et al. Cost-effectiveness analysis of universal varicella vaccination in Turkey using a dynamic transmission model. PLoS One. 2019;14(8):e0220921. doi:10.1371/journal.pone.0220921
  • Castillo-Chavez C, Hethcote HW, Andreasen V, Levin SA, Liu WM. Epidemiological models with age structure, proportionate mixing, and cross-immunity. J Math Biol. 1989;27(3):233–258. doi:10.1007/BF00275810
  • World Health Organization. WHO vaccine-preventable diseases: monitoring system 2018. Available from: http://apps.who.int/immunization_monitoring/globalsummary/countries?Countrycriteria%5Bcountry%5D%5B%5D=ITA. Accessed March 18, 2020.
  • Department of Economic and Social Affairs. Population Prospects: The 2017 Revision. United Nations: Population Division; 2017.
  • Fumanelli L, Ajelli M, Manfredi P, Vespignani A, Merler S. Inferring the structure of social contacts from demographic data in the analysis of infectious diseases spread. PLoS Comput Biol. 2012;8(9):e1002673. doi:10.1371/journal.pcbi.1002673
  • Agenzia Nazionale per i Servizi Sanitari Regionali. Tariffario Prestazioni Sanitarie Specialistiche Ambulatoriali - Visita Generale Agenzia Nazionale per i Servizi Sanitari Regionali; 2014.
  • Azzari C, Massai C, Poggiolesi C, et al. Cost of varicella-related hospitalisations in an Italian paediatric hospital: comparison with possible vaccination expenses. Curr Med Res Opin. 2007;12:2945–2954. doi:10.1185/030079907X242610
  • Trucchi C, Gabutti G, Rota MC, Bella A. Burden of varicella in Italy, 2001–2010: analysis of data from multiple sources and assessment of universal vaccination impact in three pilot regions. J Microbiol. 2015;64(11):1387–1394.
  • Morandi DI. Prestazioni specialistiche ambulatoriali Confronto tra le tariffe nazionale. Agenzia Nazionale per i Servizi Sanitari Regionali; 2014.
  • Boccalini S, Bonanni P, Bechini A. Preparing to introduce the varicella vaccine into the Italian immunisation programme: varicella-related hospitalisations in Tuscany, 2004-2012. Euro Surveill. 2016;21(24). doi:10.2807/1560-7917.ES.2016.21.24.30257
  • Ministero dell’Economia e delle Finanze. Libro verde della spesa pubblica 2007 - aggiornato con l’indice dei prezzi al consumo Ministero dell’Economia e delle Finanze. 2007.
  • Agenzia Nazionale per i Servizi Sanitari Regionali. Tariffario Prestazioni Sanitarie Specialistiche Ambulatoriali - Radiografia del torace di routine Agenzia Nazionale per i Servizi Sanitari Regionali. 2014.
  • Coudeville L, Brunot A, Giaquinto C, Lucioni C, Dervaux B. Varicella vaccination in Italy - an economic evaluation of different scenarios. PharmacoEconomics. 2004;22(13):839–855. doi:10.2165/00019053-200422130-00003
  • EuroStat. Retribuzioni e costo del lavoro. 2018.
  • Farmadati online database, Available from: https://www.farmadati.it/. Accessed in 2008
  • National Law N. 386/1974, included in the National Official Bulletin “GU Serie Generale n.225 del 29-08-1974”, art. N. 9, Link: https://www.gazzettaufficiale.it/eli/id/1974/08/29/074U0386/sg
  • Schink T, Holstiege J, Kowalzik F, Zepp F, Garbe E. Risk of febrile convulsions after MMRV vaccination in comparison to MMR or MMR+V vaccination. Vaccine. 2014;32(6):645–650. doi:10.1016/j.vaccine.2013.12.011
  • Ma S-J, Xiong Y-Q, Jiang L-N, Chen Q. Risk of febrile seizure after measles-mumps-rubella-varicella vaccine: a systematic review and meta-analysis. Vaccine. 2015;33(31):3636–3649. doi:10.1016/j.vaccine.2015.06.009
  • Kowalzik F, Faber J, Knuf M. MMR and MMRV vaccines. Vaccine. 2018;36(36):5402–5407. doi:10.1016/j.vaccine.2017.07.051
  • Gabutti G, Kuhdari P, Ferioli S, Trucchi C. Hospital admissions for seizure in Italy: a decennial retrospective analysis with a special focus on the burden in the pediatric age. Neurol Sci. 2015;36(9):1667–1673. doi:10.1007/s10072-015-2230-1
  • Christensen H, Trotter CL. Modelling the cost-effectiveness of catch-up ‘MenB’ (Bexsero) vaccination in England. Vaccine. 2017;35(2):208–211. doi:10.1016/j.vaccine.2016.11.076
  • Supplemento Ordinario n.8 alla Gazzetta Ufficiale n.23 - Tariffe delle prestazioni di assistenza ospedaliera per acuti - Convulsioni e cefalea.  2012
  • Kuter B, Matthews H, Shinefield H, et al. Ten Year Follow-up of Healthy Children Who Received One or Two Injections of Varicella Vaccine. Pediatr Res. 2004;23(2):132–137.
  • Holl K, Sauboin C, Amodio E, Bonanni P, Gabutti G. Coverage, efficacy or dosing interval: which factor predominantly influences the impact of routine childhood vaccination for the prevention of varicella? A model-based study for Italy. BMC Public Health. 2016;16(1):1103. doi:10.1186/s12889-016-3738-x
  • Ouwens MJNM, Littlewood KJ, Sauboin C, et al. The impact of 2-dose routine measles, mumps, rubella, and varicella vaccination in France on the epidemiology of varicella and zoster using a dynamic model with an empirical contact matrix. Clin Ther. 2017;37(4):816–829. doi:10.1016/j.clinthera.2014.12.017
  • Prymula R, Riise Bergsaker M, Esposito S, et al. Protection against varicella with two doses of combined measles-mumps-rubella-varicella vaccine versus one dose of monovalent varicella vaccine: a multicentre, observer-blind, randomised, controlled trial. Lancet. 2014;383(9925):1313–1324. doi:10.1016/S0140-6736(12)61461-5
  • Sauboin C, Holl K, Bonanni P, et al. The impact of childhood varicella vaccination on the incidence of herpes zoster in the general population: modelling the effect of exogenous and endogenous varicella-zoster virus immunity boosting. BMC Infect Dis. 2019;19(1):126. doi:10.1186/s12879-019-3759-z
  • Povey M, Henry O, Riise Bergsaker MA, et al. Protection against varicella with two doses of combined measles-mumps-rubella-varicella vaccine or one dose of monovalent varicella vaccine: 10-year follow-up of a Phase 3 multicentre, observer-blind, randomised, controlled trial. Lancet Infect Dis. 2019;19(3):287–297. doi:10.1016/S1473-3099(18)30716-3
  • Quinn HE, Gidding HF, Marshall HS, et al. Varicella vaccine effectiveness over 10 years in Australia; moderate protection from 1-dose program. J Infect. 2019;78(3):220–225. doi:10.1016/j.jinf.2018.11.009
  • Zhu S, Zeng F, Xia L, He H, Zhang J. Incidence rate of breakthrough varicella observed in healthy children after 1 or 2 doses of varicella vaccine: results from a meta-analysis. Am J Infect Control. 2018;46(1):e1–e7. doi:10.1016/j.ajic.2017.07.029
  • Yin M, Xu X, Liang Y, Ni J. Effectiveness, immunogenicity and safety of one vs. two-dose varicella vaccination: a meta-analysis. Expert Rev Vaccines. 2018;17(4):351–362. doi:10.1080/14760584.2018.1433999
  • Marin M, Marti M, Kambhampati A, Jeram SM, Seward JF. Global varicella vaccine effectiveness: a meta-analysis. Pediatrics. 2016;137(3):e20153741. doi:10.1542/peds.2015-3741
  • Cheng H, Chang L, Lu C, Huang L. Epidemiology of breakthrough varicella after the implementation of a universal varicella vaccination program in Taiwan, 2004–2014. Sci Rep. 2018;8(1):1. doi:10.1038/s41598-018-35451-y
  • Littlewood KJ, Ouwens MJ, Sauboin C, Tehard B, Alain S, Denis F. Cost-effectiveness of routine varicella vaccination using the measles, mumps, rubella and varicella vaccine in France: an economic analysis based on a dynamic transmission model for varicella and herpes zoster. Clin Ther. 2015;37(7):830–841. doi:10.1016/j.clinthera.2015.01.006
  • Attema AE, Brouwer W, Claxton K. Discounting in economic evaluations. PharmacoEconomics. 2018;36(7):745–758. doi:10.1007/s40273-018-0672-z
  • Gabutti G, Rota MC, De Donno A, et al. Sero-epidemiology of VZV infection in Italy: impact evaluation of extensive vaccination. Epidemiol Prev. 2014;38(6):57–61.
  • World Health Organization. Weekly epidemiological record 2014
  • World Health Organization. Guide for Standardization of Economic Evaluations of Immunization Programmes; 2008.
  • Centers for Disease Control and Prevention. Direct and Indirect Effects of Routine Vaccination of Children with 7-Valent Pneumococcal Conjugate Vaccine on Incidence of Invasive Pneumococcal Disease–United States, 1998–2003; 2005.
  • Drolet M, Bénard É, Boily M-C, et al. Population-level impact and herd effects following human papillomavirus vaccination programmes: a systematic review and meta-analysis. Lancet Infect Dis. 2015;15(5):565–580. doi:10.1016/S1473-3099(14)71073-4
  • Department of Economic and Social Affairs. Birth by Age of Mother - World Population Prospects: 2017 Revision. United Nations: Population Division; 2017.
  • Hoang TV, Coletti P, Melegaro A, et al. A systematic review of social contact surveys to inform transmission models of close contact infections. BioRxiv. 2018.
  • van Hoek AJ, Melegaro A, Gay N, Bilcke J, Edmunds WJ. The cost-effectiveness of varicella and combined varicella and herpes zoster vaccination programmes in the United Kingdom. Vaccine. 2012;30(6):1225–1234. doi:10.1016/j.vaccine.2011.11.026
  • Spackova M, Wiese-Posselt M, Dehnert M, Matysiak-Klose D, Heininger U, Siedler A. Comparative varicella vaccine effectiveness during outbreaks in day-care centres. Vaccine. 2010;28(3):686–691. doi:10.1016/j.vaccine.2009.10.086
  • Giaquinto C, Gabutti G, Baldo V, et al. Impact of a vaccination programme in children vaccinated with ProQuad, and ProQuad-specific effectiveness against varicella in the Veneto region of Italy. BMC Infect Dis. 2018;18(1):103. doi:10.1186/s12879-018-3017-9