254
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

A Systematic Review and Statistical Analysis of Factors Influencing the Cost-Effectiveness of Transcatheter Aortic Valve Implantation for Symptomatic Severe Aortic Stenosis

ORCID Icon, , , , &
Pages 459-475 | Received 23 Nov 2022, Accepted 15 May 2023, Published online: 14 Jun 2023

References

  • Carabello BA, Paulus WJ. Aortic stenosis. Lancet. 2009;373(9667):956–966. doi:10.1016/S0140-6736(09)60211-7
  • Joseph J, Naqvi SY, Giri J, et al. Aortic Stenosis: pathophysiology, Diagnosis, and Therapy. Am J Med. 2017;130(3):253–263. doi:10.1016/j.amjmed.2016.10.005
  • Dweck MR, Boon NA, Newby DE. Calcific Aortic Stenosis. J Am Coll Cardiol. 2012;60(19):1854–1863. doi:10.1016/j.jacc.2012.02.093
  • Bates ER. Treatment options in severe aortic stenosis. Circulation. 2011;124(3):355–359. doi:10.1161/CIRCULATIONAHA.110.974204
  • Turina J, Hess O, Sepulcri F, et al. Spontaneous course of aortic valve disease. Eur Heart J. 1987;8(5):471–483. doi:10.1093/oxfordjournals.eurheartj.a062307
  • Schwarz F, Baumann P, Manthey J, et al. The effect of aortic valve replacement on survival. Circulation. 1982;66(5):1105–1110. doi:10.1161/01.CIR.66.5.1105
  • Ramlawi B, Ramchandani M, Reardon MJ. Surgical Approaches to Aortic Valve Replacement and Repair—Insights and Challenges. Int Cardiol Rev. 2014;9(1):32.
  • Marquis-Gravel G, Redfors B, Leon MB, et al. Medical treatment of aortic stenosis. Circulation. 2016;134(22):1766–1784. doi:10.1161/CIRCULATIONAHA.116.023997
  • Cribier A. Development of transcatheter aortic valve implantation (TAVI): a 20-year odyssey. Arch Cardiovasc Dis. 2012;105(3):146–152. doi:10.1016/j.acvd.2012.01.005
  • Cribier A, Eltchaninoff H, Bash A, et al. Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: first human case description. Circulation. 2002;106(24):3006–3008. doi:10.1161/01.CIR.0000047200.36165.B8
  • Clayton B, Morgan-Hughes G, Roobottom C. Transcatheter aortic valve insertion (TAVI): a review. Br J Radiol. 2014;87(1033):1033. doi:10.1259/bjr.20130595
  • Biasco L, Ferrari E, Pedrazzini G, et al. Access Sites for TAVI: patient Selection Criteria, Technical Aspects, and Outcomes. Front Cardiovascular Med. 2018;5:88. doi:10.3389/fcvm.2018.00088
  • Branny M, Branny P, Hudec M, et al. Alternative Access Routes for Transcatheter Aortic Valve Implantation (TAVI). Cor et Vasa. 2017;59(1):e10e16.
  • Walther T, Simon P, Dewey T, et al. Transapical Minimally Invasive Aortic Valve Implantation. Circulation. 2007;116(11):653. doi:10.1161/CIRCULATIONAHA.106.677237
  • Leon MB, Smith CR, Mack M, et al. Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery. N Eng J Med. 2010;363(17):1597–1607. doi:10.1056/NEJMoa1008232
  • Smith CR, Leon MB, Mack MJ, et al. Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients. n Engl j Med. 2011;364:2187–2198. doi:10.1056/NEJMoa1103510
  • Lanz J, Kim W-K, Walther T, et al. Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement in patients with symptomatic severe aortic stenosis: a randomised non-inferiority trial. Lancet. 2019;394(10209):1619–1628. doi:10.1016/S0140-6736(19)32220-2
  • Makkar RR, Cheng W, Waksman R, et al. Self-expanding intra-annular versus commercially available transcatheter heart valves in high and extreme risk patients with severe aortic stenosis (PORTICO IDE): a randomised, controlled, non-inferiority trial. Lancet. 2020;396(10252):669–683. doi:10.1016/S0140-6736(20)31358-1
  • Thiele H, Kurz T, Feistritzer H-J, et al. Comparison of newer generation self-expandable vs. balloon-expandable valves in transcatheter aortic valve implantation: the randomized SOLVE-TAVI trial. Eur Heart J. 2020;41(20):1890–1899. doi:10.1093/eurheartj/ehaa036
  • Feistritzer H-J, Kurz T, Stachel G, et al. Impact of anesthesia strategy and valve type on clinical outcomes after transcatheter aortic valve replacement. J Am Coll Cardiol. 2021;77(17):2204–2215. doi:10.1016/j.jacc.2021.03.007
  • Leon MB, Smith CR, Mack MJ, et al. Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients. N Eng J Med. 2016;374(17):1609–1620. doi:10.1056/NEJMoa1514616
  • Mack MJ, Leon MB, Thourani VH, et al. Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients. N Eng J Med. 2019;380(18):1695–1705. doi:10.1056/NEJMoa1814052
  • Thourani VH, Kodali S, Makkar RR, et al. Transcatheter aortic valve replacement versus surgical valve replacement in intermediate-risk patients: a propensity score analysis. Lancet. 2016;387(10034):2218–2225. doi:10.1016/S0140-6736(16)30073-3
  • Stachel G, Abdel-Wahab M, De waha-thiele S, et al. Paravalvular Regurgitation According to Transcatheter Aortic Valve Prosthesis Type: insights From the Randomized SOLVE-TAVI Trial. Cardiovascular Imaging. 2021;14(6):1277–1279. doi:10.1016/j.jcmg.2020.10.025
  • Reardon MJ, Van Mieghem NM, Popma JJ, et al. Surgical or Transcatheter Aortic-Valve Replacement in Intermediate-Risk Patients. N Eng J Med. 2017;376(14):1321–1331. doi:10.1056/NEJMoa1700456
  • Popma JJ, Deeb GM, Yakubov SJ, et al. Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients. N Eng J Med. 2019;380(18):1706–1715. doi:10.1056/NEJMoa1816885
  • Genereux P, Head SJ, Wood DA, et al. Transcatheter aortic valve implantation 10-year anniversary: review of current evidence and clinical implications. Eur Heart J. 2012;33(19):2388–2398. doi:10.1093/eurheartj/ehs220
  • Kahlert P, Knipp SC, Schlamann M, et al. Silent and apparent cerebral ischemia after percutaneous transfemoral aortic valve implantation: a diffusion-weighted magnetic resonance imaging study. Circulation. 2010;121(7):870–878. doi:10.1161/CIRCULATIONAHA.109.855866
  • Siontis GCM, Jüni P, Pilgrim T, et al. Predictors of Permanent Pacemaker Implantation in Patients With Severe Aortic Stenosis Undergoing TAVR: a Meta-Analysis. J Am Coll Cardiol. 2014;64(2):129–140. doi:10.1016/j.jacc.2014.04.033
  • Writing Committee M, Otto CM, Nishimura RA, et al. 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: executive Summary: a Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2021;77(4):450–500. doi:10.1016/j.jacc.2020.11.035
  • Vahanian A, Beyersdorf F, Praz F. 2021 ESC/EACTS Guidelines for the management of valvular heart disease. Eur j Cardio Thoracic Surg. 2021;60(4):727–800. doi:10.1093/ejcts/ezab389
  • Authority, H.I.a.Q. Health Technology Assessment of Transcatheter Aortic Valve Implantation (TAVI) in Patients with Severe Symptomatic Aortic Stenosis at Low and Intermediate Risk of Surgical Complications; 2019.
  • Health Quality O. Transcatheter Aortic Valve Implantation for Treatment of Aortic Valve Stenosis: a Health Technology Assessment. Ont Health Technol Assess Ser. 2016;16(19):1–94.
  • Group, H.I.S.a.t.S.H.T. Transcatheter Aortic Valve Implantation (TAVI) for the Treatment of Patients with Severe Symptomatic Aortic Stenosis Who are at Intermediate Surgical Risk; 2019.
  • Sante, H.A.D. SAPIEN 3: Traitement de la sténose aortique sévère symptomatique en France chez les patients à faible risque chirurgical; 2021.
  • Committee, M.S.A. Public Summary Document: Application No. 1361.2: Transcatheter Aortic Valve Implantation via Transfemoral Delivery. Canberra (ACT): Medical Services Advisory Committee; 2016.
  • Himmels JP, Flottorp SA, Stoinska-Schneider AK, et al. Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) for Patients with Severe Aortic Stenosis and Low Surgical Risk and Across Surgical Risk Groups: A Health Technology Assessment. Heart Lung Circulation. 2021;30:1918.
  • Eaton J, Mealing S, Thompson J, et al. Is transcatheter aortic valve implantation (TAVI) a cost-effective treatment in patients who are ineligible for surgical aortic valve replacement? A systematic review of economic evaluations. J Med Econ. 2014;17(5):365–375. doi:10.3111/13696998.2014.903256
  • Gialama F, Prezerakos P, Apostolopoulos V, et al. Systematic review of the cost-effectiveness of transcatheter interventions for valvular heart disease. Eur Heart J Quality Care Clin Outcomes. 2018;4(2):81–90. doi:10.1093/ehjqcco/qcx049
  • Indraratna P, Ang SC, Gada H, et al. Systematic review of the cost-effectiveness of transcatheter aortic valve implantation. J Thoracic Cardiovascular Surg. 2014;148(2):509–514. doi:10.1016/j.jtcvs.2013.10.023
  • Shields GE, Elvidge J. Challenges in synthesising cost-effectiveness estimates. Syst Rev. 2020;9(1):1–7. doi:10.1186/s13643-020-01536-x
  • Friedman J, Hastie T, Tibshirani R. The Elements of Statistical Learning. New York: Springer series in statistics; 2001.
  • Watt M, Mealing S, Eaton J, et al. Cost-effectiveness of transcatheter aortic valve replacement in patients ineligible for conventional aortic valve replacement. Heart. 2012;98(5):370–376. doi:10.1136/heartjnl-2011-300444
  • Sehatzadeh S, Doble B, Xie F, et al. Transcatheter aortic valve implantation (TAVI) for treatment of aortic valve stenosis: an evidence-based Analysis (part B). Ont Health Technol Assess Ser. 2012;12(14):1–62.
  • Reynolds MR, Magnuson EA, Lei Y, et al. Cost-effectiveness of transcatheter aortic valve replacement compared with surgical aortic valve replacement in high-risk patients with severe aortic stenosis: results of the PARTNER (Placement of Aortic Transcatheter Valves) trial (Cohort A). J Am Coll Cardiol. 2012;60(25):2683–2692. doi:10.1016/j.jacc.2012.09.018
  • Doble B, Blackhouse G, Goeree R, et al. Cost-effectiveness of the Edwards SAPIEN transcatheter heart valve compared with standard management and surgical aortic valve replacement in patients with severe symptomatic aortic stenosis: a Canadian perspective. J Thoracic Cardiovascul Surg. 2013;146(1):52–60.e53. doi:10.1016/j.jtcvs.2012.06.018
  • Hancock-Howard RL, Feindel CM, Rodes-Cabau J, et al. Cost effectiveness of transcatheter aortic valve replacement compared to medical management in inoperable patients with severe aortic stenosis: canadian analysis based on the PARTNER Trial Cohort B findings. J Med Econ. 2013;16(4):566–574. doi:10.3111/13696998.2013.770747
  • Murphy A, Fenwick E, Toff WD, et al. Transcatheter aortic valve implantation for severe aortic stenosis: the cost-effectiveness case for inoperable patients in the United Kingdom. Int J Technol Assess Health Care. 2013;29(1):12–19. doi:10.1017/S0266462312000670
  • Simons CT, Cipriano LE, Shah RU, et al. Transcatheter aortic valve replacement in nonsurgical candidates with severe, symptomatic aortic stenosis: a cost-effectiveness analysis. Circulation. Cardiovascular Qual Outcomes. 2013;6(4):419–428. doi:10.1161/CIRCOUTCOMES.113.000280
  • Brecker S, Mealing S, Padhiar A, et al. Cost-utility of transcatheter aortic valve implantation for inoperable patients with severe aortic stenosis treated by medical management: a UK cost-utility analysis based on patient-level data from the ADVANCE study. Open Heart. 2014;1(1):e000155. doi:10.1136/openhrt-2014-000155
  • Sante HAD. Système Medtronic Corevalve; 2017.
  • Kodera S, Kiyosue A, Ando J, et al. Cost effectiveness of transcatheter aortic valve implantation in patients with aortic stenosis in Japan. J Cardiol. 2018;71(3):223–229. doi:10.1016/j.jjcc.2017.10.008
  • Inoue S, Nakao K, Hanyu M, et al. Cost-effectiveness of transcatheter aortic valve implantation using a balloon-expandable valve in Japan: experience From the Japanese pilot health technology assessment. Value Health Reg Issues. 2020;21:82–90. doi:10.1016/j.vhri.2019.07.013
  • Lorenzoni V, Barbieri G, Saia F, et al. The cost-effectiveness of transcatheter aortic valve implantation: exploring the Italian National Health System perspective and different patient risk groups. Eur J Health Econ. 2021;21:21.
  • Pinar E, Hurtado J, Robles M, et al. Cost-effectiveness analysis of the SAPIEN 3 transcatheter aortic valve implant in patients with symptomatic severe aortic stenosis. Rev Esp Cardiol. 2021;17:17.
  • Gada H, Agarwal S, Marwick TH. Perspective on the cost-effectiveness of transapical aortic valve implantation in high-risk patients: outcomes of a decision-analytic model. Ann Cardiothorac Surg. 2012;1(2):145–155. doi:10.3978/j.issn.2225-319X.2012.06.12
  • Gada H, Kapadia SR, Tuzcu EM, et al. Markov model for selection of aortic valve replacement versus transcatheter aortic valve implantation (without replacement) in high-risk patients. Am J Card. 2012;109(9):1326–1333. doi:10.1016/j.amjcard.2011.12.030
  • Fairbairn TA, Meads DM, Hulme C, et al. The cost-effectiveness of transcatheter aortic valve implantation versus surgical aortic valve replacement in patients with severe aortic stenosis at high operative risk. Heart. 2013;99(13):914–920. doi:10.1136/heartjnl-2013-303722
  • Bayón J, Gutiérrez Iglesias A, Mateos Del Pino M, et al. Análisis coste-efectividad del recambio valvular aórtico mediante prótesis valvular percutánea frente al tratamiento quirúrgico habitual. Ministerio de Sanidad, Servicios Sociales e Igualdad; Servicio de Evaluación de Tecnologías Sanitarias del País Vasco. Informes de Evaluación de Tecnologías Sanitarias: OSTEBA; 2014.
  • Reynolds MR, Lei Y, Wang K, et al. Cost-effectiveness of transcatheter aortic valve replacement with a self-expanding prosthesis versus surgical aortic valve replacement. J Am Coll Cardiol. 2016;67(1):29–38. doi:10.1016/j.jacc.2015.10.046
  • Geisler BP, Huygens SA, Reardon MJ, et al. Cost-effectiveness and projected survival of self-expanding transcatheter versus surgical aortic valve replacement for high risk patients in a european setting: a dutch analysis based on the corevalve high risk trial. Structural Heart. 2017;1(5–6):267–274. doi:10.1080/24748706.2017.1381357
  • Tarride JE, Luong T, Goodall G, et al. A Canadian cost-effectiveness analysis of SAPIEN 3 transcatheter aortic valve implantation compared with surgery, in intermediate and high-risk severe aortic stenosis patients. Clinicoecon Outcomes Res. 2019;11:477–486. doi:10.2147/CEOR.S208107
  • Ferreira-Gonzalez I, You JJ, Karanicolas PJ, et al. Evidence of the cost-effectiveness of Edwards Sapien transcatheter aortic valve implantation (TAVI) in high-risk patients with symptomatic aortic stenosis in Spain: preliminary results. Pharmacoeconomics. 2013;10(1):1–13. Spanish.
  • Orlando R, Pennant M, Rooney S, et al. Cost-effectiveness of transcatheter aortic valve implantation (TAVI) for aortic stenosis in patients who are high risk or contraindicated for surgery: a model-based economic evaluation. Health Technol Asses. 2013;17(33):1–86. doi:10.3310/hta17330
  • Tam DY, Hughes A, Fremes SE, et al. A cost-utility analysis of transcatheter versus surgical aortic valve replacement for the treatment of aortic stenosis in the population with intermediate surgical risk. J Thoracic Cardiovascul Surg. 2018;155(5):1978–1988.e1971. doi:10.1016/j.jtcvs.2017.11.112
  • Tam DY, Hughes A, Wijeysundera HC, et al. Cost-effectiveness of self-expandable transcatheter aortic valves in intermediate-risk patients. Ann Thorac Surg. 2018;106(3):676–683. doi:10.1016/j.athoracsur.2018.03.069
  • Baron SJ, Wang K, House JA, et al. Cost-Effectiveness of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis at Intermediate Risk. Circulation. 2019;139(7):877–888. doi:10.1161/CIRCULATIONAHA.118.035236
  • Goodall G, Lamotte M, Ramos M, et al. Cost-effectiveness analysis of the SAPIEN 3 TAVI valve compared with surgery in intermediate-risk patients. J Med Econ. 2019;22(4):289–296. doi:10.1080/13696998.2018.1559600
  • Fagerlund BC, Stoinska-Schneider A, Lauvrak V, et al. Health technology assessment of Transcatether aortic valve implantation (TAVI) as treatment of patients with severe aortic stenosis and intermediate surgical risk–Part 2. Health Economic Evaluat. 2019.
  • Zhou J, Liew D, Duffy SJ, et al. Cost-effectiveness of transcatheter aortic valve implantation compared to surgical aortic valve replacement in the intermediate surgical risk population. Int J Cardiol. 2019;294:17–22. doi:10.1016/j.ijcard.2019.06.057
  • Wales HT. Evidence appraisal report: transcatheter aortic valve implantation to treat people with severe symptomatic aortic stenosis, who are at intermediate surgical risk; 2020.
  • Geisler BP, Jørgensen TH, Thyregod HGH, et al. Cost-effectiveness of transcatheter versus surgical aortic valve replacement in patients at lower surgical risk: results from the NOTION trial. Eurointervention. 2019;15(11):e959–e967. doi:10.4244/EIJ-D-18-00847
  • Tam DY, Azizi PM, Fremes SE, et al. The cost-effectiveness of transcatheter aortic valve replacement in low surgical risk patients with severe aortic stenosis. Eur Heart J Qual Care Clin Outcomes. 2020;09:09.
  • Gilard M, Eltchaninoff H, Iung B, et al. Cost-effectiveness analysis of sapien 3 transcatheter aortic valve implantation procedure compared with surgery in patients with severe aortic stenosis at low risk of surgical mortality in France. Value Health. 2021;25(4):605–613. doi:10.1016/j.jval.2021.10.003
  • Sante HAD. Medtronic CoreValve Evolut R et Evolut PRO: traitement de la sténose aortique sévère symptomatique en France chez les patients à faible risque chirurgical; 2021.
  • Zhou JY, Liew D, Duffy SJ, et al. Cost-effectiveness of transcatheter versus surgical aortic valve replacement in low-risk patients with severe aortic stenosis. Heart Lung Circ. 2021;30(4):547–554. doi:10.1016/j.hlc.2020.09.934
  • Kuntjoro I, Tay E, Hon J, et al. Cost-effectiveness of transcatheter aortic valve implantation in intermediate and low risk severe aortic stenosis patients in Singapore. Ann Acad Med Singapore. 2020;49(7):423–433. doi:10.47102/annals-acadmedsg.2019198
  • Reynolds MR, Baron SJ, Cohen DJ. Economic Implications of Transcatheter Aortic Valve Replacement in Patients at Intermediate Surgical Risk. Circulation. 2016;134(19):1416–1418. doi:10.1161/CIRCULATIONAHA.116.021962
  • Reynolds MR, Magnuson EA, Wang K, et al. Cost-effectiveness of transcatheter aortic valve replacement compared with standard care among inoperable patients with severe aortic stenosis: results from the placement of aortic transcatheter valves (PARTNER) trial (Cohort B). Circulation. 2012;125(9):1102–1109. doi:10.1161/CIRCULATIONAHA.111.054072
  • Baron SJ, Wang K, Arnold SV, et al. Cost-Effectiveness of Transcatheter Mitral Valve Repair Versus Medical Therapy in Patients with Heart Failure and Secondary Mitral Regurgitation: results from the COAPT Trial. Circulation. 2019;140(23):1881–1891. doi:10.1161/CIRCULATIONAHA.119.043275
  • Young C, Horton J. Transcatheter Aortic Valve Implantation for Patients with Severe Symptomatic Aortic Stenosis. Canadian J Health Technol. 2021;1(7). doi:10.51731/cjht.2021.100
  • Chotnoppharatphatthara P, Yoodee V, Taesotikul S, et al. Transcatheter aortic valve implantation in patients with severe symptomatic aortic valve stenosis: systematic review of cost-effectiveness analysis. Eur J Health Economics. 2022;1–18.
  • Auffret V, Lefevre T, Van Belle E, et al. Temporal trends in transcatheter aortic valve replacement in France: France 2 to France TAVI. J Am Coll Cardiol. 2017;70(1):42–55. doi:10.1016/j.jacc.2017.04.053