Modelling the Costs of Sublingual Immunotherapy versus Subcutaneous Immunotherapy Based on Clinical Appointments and Impacts of Patient Travel in Sweden

References

• Holmström M, Davidsson Å, Stridh B, et al. Allergisk rinit hos barn och vuxna [Allergic rhinitis in children and adults - international recommendations adapted to the clinical situation in Sweden]. Lakartidningen. 2023;120:23041. Swedish.
   PubMedGoogle Scholar
• Small P, Keith PK, Kim H. Allergic rhinitis. Allergy Asthma Clin Immunol. 2018;14(S2):51. doi:10.1186/s13223-018-0280-7
   PubMed Web of Science ®Google Scholar
• Varshney J, Varshney H. Allergic rhinitis: an overview. Indian J Otolaryngol Head Neck Surg. 2015;67(2):143–149. doi:10.1007/s12070-015-0828-5
   PubMedGoogle Scholar
• Tkacz JP, Rance K, Waddell D, et al. Real-world evidence costs of allergic rhinitis and allergy immunotherapy in the commercially insured United States population. Curr Med Res Opin. 2021;37(6):957–965. doi:10.1080/03007995.2021.1903848
   PubMed Web of Science ®Google Scholar
• Kremer B, Den Hartog HM, Jolles J. Relationship between allergic rhinitis, disturbed cognitive functions and psychological well-being. Clin Exp Allergy. 2002;32(9):1310–1315. doi:10.1046/j.1365-2745.2002.01483.x
   PubMed Web of Science ®Google Scholar
• Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy. 2008;63(Suppl 86):8–160. doi:10.1111/j.1398-9995.2007.01620.x
   PubMed Web of Science ®Google Scholar
• Greiner AN, Hellings PW, Rotiroti G, et al. Allergic rhinitis. Lancet. 2011;378(9809):2112–2122. doi:10.1016/S0140-6736(11)60130-X
   PubMed Web of Science ®Google Scholar
• Bousquet J, Neukirch F, Bousquet PJ, et al. Severity and impairment of allergic rhinitis in patients consulting in primary care. J Allergy Clin Immunol. 2006;117(1):158–162. doi:10.1016/j.jaci.2005.09.047
   PubMed Web of Science ®Google Scholar
• Eriksson J, Ekerljung L, Rönmark E, et al. Update of prevalence of self-reported allergic rhinitis and chronic nasal symptoms among adults in Sweden. Clin Respir J. 2012;6(3):159–168. doi:10.1111/j.1752-699X.2011.00269.x
   PubMed Web of Science ®Google Scholar
• Cardell L-O, Olsson P, Andersson M, et al. TOTALL: high cost of allergic rhinitis-a national Swedish population-based questionnaire study. NPJ Prim Care Respir Med. 2016;26(1):15082. doi:10.1038/npjpcrm.2015.82
   PubMedGoogle Scholar
• Hellgren J, Cervin A, Nordling S, et al. Allergic rhinitis and the common cold - high cost to society. Allergy. 2010;65(6):776–783. doi:10.1111/j.1398-9995.2009.02269.x
   PubMed Web of Science ®Google Scholar
• Sur DKC, Plesa ML. Treatment of allergic rhinitis. Am Fam Physician. 2015;92(11):985–992.
   PubMed Web of Science ®Google Scholar
• Varney VA, Gaga M, Frew AJ, et al. Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs. BMJ. 1991;302(6771):265–269. doi:10.1136/bmj.302.6771.265
   PubMed Web of Science ®Google Scholar
• Sánchez-Borges M, Bernstein DI, Calabria C. Subcutaneous immunotherapy safety: incidence per surveys and risk factors. Immunol Allergy Clin North Am. 2020;40(1):25–39. doi:10.1016/j.iac.2019.09.001
   PubMed Web of Science ®Google Scholar
• Dretzke J, Meadows A, Novielli N, et al. Subcutaneous and sublingual immunotherapy for seasonal allergic rhinitis: a systematic review and indirect comparison. J Allergy Clin Immunol. 2013;131(5):1361–1366. doi:10.1016/j.jaci.2013.02.013
   PubMed Web of Science ®Google Scholar
• Saporta D. Efficacy of sublingual immunotherapy versus subcutaneous injection immunotherapy in allergic patients. J Environ Public Health. 2012;2012:492405. doi:10.1155/2012/492405
   PubMedGoogle Scholar
• Cardell L-O, Sterner T, Ahmed W, et al. Modelling the impact of sublingual immunotherapy versus subcutaneous immunotherapy on patient travel time and CO2 emissions in Sweden. Sci Rep. 2024;14(1):1575. doi:10.1038/s41598-024-51925-8
   PubMed Web of Science ®Google Scholar
• Ali F. NICE’s strategy on sustainability: current progress and next steps. NICE; 2020. Available from: https://www.nice.org.uk/news/blog/current-progress-and-next-steps-on-sustainability. Accessed May 31, 2024.
   Google Scholar
• Lenzen M, Malik A, Li M, et al. The environmental footprint of health care: a global assessment. Lancet Planet Health. 2020;4(7):e271–e279. doi:10.1016/S2542-5196(20)30121-2
   PubMedGoogle Scholar
• Wallskär H. Fler får immunterapi mot allergier. LäkemedelsVärlden; 2022. Available from: https://www.lakemedelsvarlden.se/immunterapi-mot-allergier-okar/. Accessed May 31, 2024.
   Google Scholar
• emc. ITULAZAX 12 SQ-Bet - Summary of Product Characteristics (SmPC); 2022. Available from: https://www.medicines.org.uk/emc/product/12906. Accessed May 31, 2024.
   Google Scholar
• FASS. Alutard SQ 5-Grass. fass.se; 2021. Available from: https://www.fass.se/LIF/product?userType=2&nplId=19901102000807. Accessed May 31, 2024.
   Google Scholar
• Pollock RF, Slættanes AK, Brandi H, et al. A cost-utility analysis of SQ® Tree SLIT-tablet versus placebo in the treatment of birch pollen allergic rhinitis from a Swedish societal perspective. Clin Outcomes Res CEOR. 2023;15:69–86.
   PubMed Web of Science ®Google Scholar
• 1177.se. Högkostnadsskydd för öppenvård. 1177. Available from: https://www.1177.se/sa-fungerar-varden/kostnader-och-ersattningar/hogkostnadsskydd-for-oppenvard/. Accessed May 31, 2024.
   Google Scholar
• FASS. Itulazax. fass.se; 2022. Available from: https://www.fass.se/LIF/product?userType=2&nplId=20180727000034. Accessed May 31, 2024.
   Google Scholar
• E-hälsomyndigheten. Raised limits in the high-cost reimbursement scheme on January 1st 2023; 2022. Available from: https://www.ehalsomyndigheten.se/languages/english/raised-limits-in-The-high-cost-reimbursement--scheme-on-january-1st-2023/.
   Google Scholar
• Buy Alutard SQ Birch suspension for injection strength series, 4 x 5 milliliters | apoteket.se. Available from: https://www.apoteket.se/produkt/alutard-sq-bjork-injektionsvatska-suspension-styrkeserie-4-x-5-milliliter-kombinationsforpackning-52520/. Accessed May 31, 2024.
   Google Scholar
• Buy Alutard SQ Birch, inj-liquid, suspension 100,000 SQ-E/mL, 5 milliliters | apoteket.se. Available from: https://www.apoteket.se/produkt/alutard-sq-bjork-injektionsvatska-suspension-100-000-sq-e-per-mL-5-milliliter-injektionsflaska-52519/. Accessed May 31, 2024.
   Google Scholar
• Energimyndigheten. Energiläget. Available from: https://www.energimyndigheten.se/statistik/energilaget/?currentTab=1. Accessed May 31, 2024.
   Google Scholar
• International Energy Agency. Fuel economy in major car markets: technology and policy drivers 2005-2017. Paris: International Energy Agency; 2019. Available from: https://www.iea.org/reports/fuel-economy-in-major-car-markets. Accessed May 31, 2024.
   Google Scholar
• Koopmanschap MA, Rutten FF. Indirect costs in economic studies: confronting the confusion. PharmacoEconomics. 1993;4(6):446–454. doi:10.2165/00019053-199304060-00006
   PubMed Web of Science ®Google Scholar
• Drummond MF, Sculpher MJ, Claxton K, et al. Methods for the Economic Evaluation of Health Care Programmes. Oxford University Press; 2015.
   Google Scholar
• Gosselin E, Lemyre L, Corneil W. Presenteeism and absenteeism: differentiated understanding of related phenomena. J Occup Health Psychol. 2013;18(1):75–86. doi:10.1037/a0030932
   PubMed Web of Science ®Google Scholar
• Average hourly earnings, including overtime pay, of manual workers in the private sector, time series. Stat. Cent. Available from: https://www.scb.se/en/finding-statistics/statistics-by-subject-area/labour-market/wages-salaries-and-labour-costs/short-term-statistics-wages-and-salaries-private-sector-klp/pong/tables-and-graphs/manual-workers/average-hourly-earnings-including-overtime-pay-of-manual-workers-in-The-private-sector-time-series/. Accessed May 31, 2024.
   Google Scholar
• Medlingsinstitutet. Lönestrukturstatistik. Medlingsinstitutet; 2019. Available from: https://www.mi.se/lonestatistik/lonestrukturstatistik/. Accessed May 31, 2024.
   Google Scholar
• SCB. Medelarbetstid (faktisk) per vecka för sysselsatta 15-74 år (AKU) efter anknytningsgrad till arbetsmarknaden, kön och ålder. År 2021 - 2022. Statistikdatabasen. Available from: http://www.statistikdatabasen.scb.se/pxweb/sv/ssd/START__AM__AM0401__AM0401S/NAKUFaktMedArbtidAr/. Accessed May 31, 2024.
   Google Scholar
• Regeringen och Regeringskansliet. Annual Leave Act (Semesterlagen). Regeringskansliet. Regeringen och Regeringskansliet; 2016. Available from: https://www.government.se/government-policy/labour-law-and-work-environment/1977480-annual-leave-act-semesterlagen/. Accessed May 31, 2024.
   Google Scholar
• Coombs NJ, Coombs JM, Vaidya UJ, et al. Environmental and social benefits of the targeted intraoperative radiotherapy for breast cancer: data from UK TARGIT-A trial centres and two UK NHS hospitals offering TARGIT IORT. BMJ Open. 2016;6(5):e010703. doi:10.1136/bmjopen-2015-010703
   PubMed Web of Science ®Google Scholar
• Andrews E, Pearson D, Kelly C, et al. Carbon footprint of patient journeys through primary care: a mixed methods approach. Br J Gen Pract. 2013;63(614):e595–603. doi:10.3399/bjgp13X671579
   PubMed Web of Science ®Google Scholar
• Vincent Rajkumar S. The high cost of prescription drugs: causes and solutions. Blood Cancer J. 2020;10(6):71. doi:10.1038/s41408-020-0338-x
   PubMed Web of Science ®Google Scholar
• Ricke K, Drouet L, Caldeira K, et al. Country-level social cost of carbon. Nat Clim Change. 2018;8(10):895–900. doi:10.1038/s41558-018-0282-y
   Web of Science ®Google Scholar
• Rennert K, Errickson F, Prest BC, et al. Comprehensive evidence implies a higher social cost of CO2. Nature. 2022;610(7933):687–692. doi:10.1038/s41586-022-05224-9
   PubMed Web of Science ®Google Scholar
• Hodgson C, Sheppard D EU carbon price tops €100 a tonne for first time. Financ Times; 2023. Available from: https://www.ft.com/content/7a0dd553-fa5b-4a58-81d1-e500f8ce3d2a. Accessed May 31, 2024.
   Google Scholar
• Rennert K, Prest BC, Pizer WA, et al. The social cost of carbon: advances in long-term probabilistic projections of population, GDP, emissions, and discount rates. Brookings; 2021. Available from: https://www.brookings.edu/articles/the-social-cost-of-carbon/. Accessed May 31, 2024.
   Google Scholar
• Anell A, Glenngård AH, Merkur S. Sweden health system review. Health Syst Transit. 2012;14:1–159.
   PubMedGoogle Scholar
• Regeringskansliet R. Central government budget in figures. Regeringskansliet. Regeringen och Regeringskansliet; 2019. Available from: https://www.government.se/government-of-sweden/ministry-of-finance/central-government-budget/central-government-budget-in-figures/. Accessed May 31, 2024.
   Google Scholar
• Department of Health and Social Care, Foreign & Commonwealth Office, Foreign, Commonwealth & Development Office. Healthcare for UK nationals living in Sweden. GOV.UK; 2021. Available from: https://www.gov.uk/guidance/healthcare-in-sweden. Accessed May 31, 2024.
   Google Scholar
• Öster K. Patientavgifter och högkostnadsskydd. 1177.se; 2023. Available from: https://www.1177.se/sa-fungerar-varden/kostnader-och-ersattningar/patientavgifter/. Accessed May 31, 2024.
   Google Scholar
• Olsson P, Skröder C, Ahlbeck L, et al. HealthSWEDE: costs with sublingual immunotherapy—a Swedish questionnaire study. Allergy Asthma Clin Immunol. 2021;17(1):55. doi:10.1186/s13223-021-00560-3
   PubMed Web of Science ®Google Scholar