HSP20 phosphorylation and airway smooth muscle relaxation

References

• Beall AC, Kato K, Goldenring JR, Rasmussen H, Brophy CM. Cyclic nucleotide-dependent vasorelaxation is associated with the phosphorylation of a small heat shock-related protein. J Biol Chem. 1997;272(17):11283–11287.
   Web of Science ®Google Scholar
• Beall A, Bagwell D, Woodrum D, et al. The small heat shock- related protein, HSP20, is phosphorylated on serine 16 during cyclic nucleotide-dependent relaxation. J Biol Chem. 1999;274(16):11344–11351.
   Web of Science ®Google Scholar
• Rembold CM, O’Connor M, Clarkson M, Wardle RL, Murphy RA. Selected contribution: HSP20 phosphorylation in nitroglycerin- and forskolin-induced sustained reductions in swine carotid media tone. J Appl Physiol. 2001;91(3):1460–1466.
   Web of Science ®Google Scholar
• Rembold CM, Foster DB, Strauss JD, Wingard CJ, Eyk JE. cGMP- mediated phosphorylation of heat shock protein 20 may cause smooth muscle relaxation without myosin light chain dephosphorylation in swine carotid artery. J Physiol. 2000;524(Pt 3):865–878.
   Web of Science ®Google Scholar
• Woodrum D, Pipkin W, Tessier D, Komalavilas P, Brophy CM. Phosphorylation of the heat shock-related protein, HSP20, mediates cyclic nucleotide-dependent relaxation. J Vasc Surg. 2003;37(4):874–881.
   Web of Science ®Google Scholar
• Flynn CR, Komalavilas P, Tessier D, et al. Transduction of biologically active motifs of the small heat shock-related protein HSP20 leads to relaxation of vascular smooth muscle. FASEB J. 2003;17(10):1358–1360.
   Google Scholar
• Flynn CR, Brophy CM, Furnish EJ, et al. Transduction of phos- phorylated heat shock-related protein 20, HSP20, prevents vasospasm of human umbilical artery smooth muscle. J Appl Physiol. 2005;98(5):1836–1845.
   Web of Science ®Google Scholar
• Komalavilas P, Penn RB, Flynn CR, et al. The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation. Am J Physiol Lung Cell Mol Physiol. 2008;294(1):L69–L78.
   Web of Science ®Google Scholar
• Watanabe M, Yoshino Y, Morimoto S. Troponin I inhibitory peptide suppresses the force generation in smooth muscle by directly interfering with cross-bridge formation. Biochem Biophys Res Commun. 2003;307(2):236–240.
   Web of Science ®Google Scholar
• Brophy CM, Beall A, Lamb S, Dickinson M, Ware DJ. Small heat shock proteins and vasospasm in human umbilical artery smooth muscle. Biol Reprod. 1997;57(6):1354–1359.
   Web of Science ®Google Scholar
• Batts TW, Klausner AP, Jin Z, et al. Increased expression of heat shock protein 20 and decreased contractile stress in obstructed rat bladder. J Urol. 2006;176(4 Pt 1):1679–1684.
   Web of Science ®Google Scholar
• Cross BE, O’Dea HM, MacPhee DJ. Expression of small heat shock-related protein 20 (HSP20) in rat myometrium is markedly decreased during late pregnancy and labour. Reproduction. 2007;133(4):807–817.
   Web of Science ®Google Scholar
• Shore SA, Moore PE. Effects of cytokines on contractile and dilator responses of airway smooth muscle. Clin Exp Pharmacol Physiol. 2002;29(10):859–866.
   Web of Science ®Google Scholar
• Amrani Y, Panettieri RA Jr. Cytokines induce airway smooth muscle cell hyperresponsiveness to contractile agonists. Thorax. 1998;53(8):713–716.
   Web of Science ®Google Scholar
• Gerthoffer WT. Calcium dependence of myosin phosphorylation and airway smooth muscle contraction and relaxation. Am J Physiol. 1986;250(4 Pt 1):C597–C604.
   Google Scholar
• Hamann KJ, Vieira JE, Halayko AJ, et al. Fas cross-linking induces apoptosis in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2000;278(3):L618–L624.
   Web of Science ®Google Scholar
• Rahman MS, Yang J, Shan LY, et al. IL-17R activation of human airway smooth muscle cells induces CXCL-8 production via a transcriptional- dependent mechanism. Clin Immunol. 2005;115(3):268–276.
   Web of Science ®Google Scholar
• Flynn CR, Smoke CC, Furnish E, et al. Phosphorylation and activation of a transducible recombinant form of human HSP20 in Escherichia coli. Protein Expr Purif. 2007;52(1):50–58.
   Web of Science ®Google Scholar
• Ikebe M, Hartshorne DJ. Effects of Ca2+ on the conformation and enzymatic activity of smooth muscle myosin. J Biol Chem. 1985;260(24):13146–13153.
   Web of Science ®Google Scholar
• Ikebe M, Hartshorne DJ. Proteolysis of smooth muscle myosin by Staphylococcus aureus protease: preparation of heavy meromyosin and subfragment 1 with intact 20,000-dalton light chains. Biochemistry. 1985;24(9):2380–2387.
   Web of Science ®Google Scholar
• Ellison PA, Sellers JR, Cremo CR. Kinetics of smooth muscle heavy meromyosin with one thiophosphorylated head. J Biol Chem. 2000;275(20):15142–15151.
   Web of Science ®Google Scholar
• Smillie LB. Preparation and identification of alpha- and betatropomyosins. Meth ods Enzymol. 1982;85(Pt B):234–241.
   Google Scholar
• Spudich JA, Watt S. The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J Biol Chem. 1971;246(15):4866–4871.
   PubMed Web of Science ®Google Scholar
• Hooft AM, Maki EJ, Cox KK, Baker JE. An accelerated state of myosin- based actin motility. Biochemistry. 2007;46(11):3513–3520.
   Web of Science ®Google Scholar
• Negre-Aminou P, van Leeuwen RE, van Thiel GC, et al. Differential effect of simvastatin on activation of Rac(1) vs activation of the heat shock protein 27-mediated pathway upon oxidative stress, in human smooth muscle cells. Biochem Pharmacol. 2002;64(10):1483–91.
   Web of Science ®Google Scholar
• Salinthone S, Singer CA, Gerthoffer WT. Inflammatory gene expression by human colonic smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2004;287(3):G627–G637.
   Web of Science ®Google Scholar
• Trinklein ND, Murray JI, Hartman SJ, Botstein D, Myers RM. The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response. Mol Biol Cell. 2004;15(3):1254–1261.
   PubMed Web of Science ®Google Scholar
• Fan GC, Chu G, Kranias EG. Hsp20 and its cardioprotection. Trends Cardiovasc Med. 2005;15(4):138–141.
   Web of Science ®Google Scholar
• Meeks MK, Ripley ML, Jin Z, Rembold CM. Heat shock protein 20-mediated force suppression in forskolin-relaxed swine carotid artery. Am J Physiol Cell Physiol. 2005;288(3):C633–C639.
   Web of Science ®Google Scholar
• Rembold CM, Meeks MK, Ripley ML, Han S. Longer muscle lengths recapitulate force suppression in swine carotid artery. Am J Physiol Heart Circ Physiol. 2007;292(2):H1065–H1070.
   Web of Science ®Google Scholar
• Pipkin W, Johnson JA, Creazzo TL, Burch J, Komalavilas P, Brophy C. Localization, macromolecular associations, and function of the small heat shock-related protein HSP20 in rat heart. Circulation. 2003;107(3):469–476.
   Web of Science ®Google Scholar
• Islamovic E, Duncan A, Bers DM, Gerthoffer WT, Mestril R. Importance of small heat shock protein 20 (HSP20) C-terminal extension in cardioprotection. J Mol Cell Cardiol. 2007;42(4):862–869.
   Web of Science ®Google Scholar
• Brophy CM, Lamb S, Graham A. The small heat shock-related protein- 20 is an actin-associated protein. J Vasc Surg. 1999;29(2):326–333.
   Web of Science ®Google Scholar
• Bukach OV, Marston SB, Gusev NB. Small heat shock protein with apparent molecular mass 20 kDa (HSP20, HSPB6) is not a genuine actin- binding protein. J Muscle Res Cell Motil. 2005 ;26(4–5):175–181.
   Web of Science ®Google Scholar
• Kato K, Goto S, Inaguma Y, Hasegawa K, Morishita R, Asano T. Purification and characterization of a 20-kDa protein that is highly homologous to alpha B crystallin. J Biol Chem. 1994;269(21):15302–15309.
   PubMed Web of Science ®Google Scholar
• Brophy CM, Dickinson M, Woodrum D. Phosphorylation of the small heat shock-related protein, HSP20, in vascular smooth muscles is associated with changes in the macromolecular associations of HSP20. J Biol Chem. 1999;274(10):6324–6329.
   Web of Science ®Google Scholar
• Sugiyama Y, Suzuki A, Kishikawa M, et al. Muscle develops a specific form of small heat shock protein complex composed of MKBP/ HSPB2 and HSPB3 during myogenic differentiation. J Biol Chem. 2000;275(2):1095–1104.
   Web of Science ®Google Scholar
• Sun X, Fontaine JM, Rest JS, Shelden EA, Welsh MJ, Benndorf R. Interaction of human HSP22 (HSPB8) with other small heat shock proteins. J Biol Chem. 2004;279(4):2394–2402.
   PubMed Web of Science ®Google Scholar
• Zantema A, Verlaan-De VM, Maasdam D, Bol S, van der EA. Heat shock protein 27 and alpha B-crystallin can form a complex, which dissociates by heat shock. J Biol Chem. 1992;267(18):12936–12941.
   Web of Science ®Google Scholar
• Batts TW, Walker JS, Murphy RA, Rembold CM. Absence of force suppression in rabbit bladder correlates with low expression of heat shock protein 20. BMC Physiol. 2005;5:16.
   Google Scholar
• Macomson SD, Brophy CM, Miller W, Harris VA, Shaver EG. Heat shock protein expression in cerebral vessels after subarachnoid hemorrhage. Neurosurgery. 2002;51(1):204–220.
   Web of Science ®Google Scholar
• Gusev NB, Bukach OV, Marston SB. Structure, properties, and probable physiological role of small heat shock protein with molecular mass 20 kD (HSP20, HSPB6). Biochemistry (Mosc). 2005;70(6):629–637.
   Web of Science ®Google Scholar
• Salinthone S, Tyagi M, Gerthoffer WT. Small heat shock proteins in smooth muscle. Pharmacol Ther. 2008;119(1):44–54.
   Web of Science ®Google Scholar
• Gerthoffer WT, T revethick MA, Murphy RA. Myosin phosphorylation and cyclic adenosine 3’,5’-monophosphate in relaxation of arterial smooth muscle by vasodilators. Circ Res. 1984;54(1):83–89.
   Web of Science ®Google Scholar
• Gerthoffer WT. Dissociation of myosin phosphorylation and active tension during muscarinic stimulation of tracheal smooth muscle. J Pharmacol Exp Ther. 1987;240(1):8–15.
   Web of Science ®Google Scholar
• Tessier DJ, Komalavilas P, Panitch A, Joshi L, Brophy CM. The small heat shock protein (HSP) 20 is dynamically associated with the actin cross-linking protein actinin. J Surg Res. 2003;111(1):152–157.
   Web of Science ®Google Scholar
• Dreiza CM, Brophy CM, Komalavilas P, et al. Transducible heat shock protein 20 (HSP20) phosphopeptide alters cytoskeletal dynamics. FASEB J. 2005;19(2):261–263.
   Google Scholar
• van de Klundert FA, de Jong WW The small heat shock proteins Hsp20 and alphaB-crystallin in cultured cardiac myocytes: differences in cellular localization and solubilization after heat stress. Eur J Cell Biol. 1999;78(8):567–472.
   Web of Science ®Google Scholar