The mean platelet volume on admission predicts unfavorable stroke outcomes in patients treated with IV thrombolysis

References

• MolinaCAMontanerJArenillasJFRiboMRubieraMAlvarez-SabínJDifferential pattern of tissue plasminogen activator-induced proximal middle cerebral artery recanalization among stroke subtypesStroke200435248649014707233
   PubMed Web of Science ®Google Scholar
• RossRAtherosclerosis – an inflammatory diseaseN Engl J Med199934021151269887164
   PubMed Web of Science ®Google Scholar
• DuyguHTurkogluCKirilmazBTurkUEffect of mean platelet volume on postintervention coronary blood flow in patients with chronic stable angina pectorisJ Invasive Cardiol200820312012418316827
   PubMed Web of Science ®Google Scholar
• ChuSGBeckerRCBergerPBMean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysisJ Thromb Haemost20108114815619691485
   PubMed Web of Science ®Google Scholar
• SenaranHIleriMAltinbaşAThrombopoietin and mean platelet volume in coronary artery diseaseClin Cardiol200124540540811346249
   PubMed Web of Science ®Google Scholar
• ChenYXiaoYLinZThe role of circulating platelets microparticles and platelet parameters in acute ischemic stroke patientsJ Stroke Cerebrovasc Dis201524102313232026169549
   PubMed Web of Science ®Google Scholar
• GreiseneggerSEndlerGHsiehKTentschertSMannhalterCLalouschekWIs elevated mean platelet volume associated with a worse outcome in patients with acute ischemic cerebrovascular events?Stroke20043571688169115143290
   PubMed Web of Science ®Google Scholar
• OjiSTomohisaDHaraWMean platelet volume is associated with early neurological deterioration in patients with branch atheromatous disease: involvement of platelet activationJ Stroke Cerebrovasc Dis20182761624163129428328
   PubMed Web of Science ®Google Scholar
• InançYGiraySInançYYusufISemihGYilmazIMean platelet volume, C-reactive protein, and prognosis in patients with acute ischemic stroke following intravenous thrombolytic treatmentMed Sci Monit2018243782378829869620
   PubMed Web of Science ®Google Scholar
• Postępowanie W udarze mózgu: wytyczne Grupy Ekspertów Sekcji Chorób Naczyniowych Polskiego Towarzystwa NeurologicznegoNeurol i Neurochir Pol201246Suppl 1
   Google Scholar
• KernanWNOvbiageleBBlackHRGuidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/ American Stroke AssociationStroke20144572160223624788967
   PubMed Web of Science ®Google Scholar
• FrankelMRMorgensternLBKwiatkowskiTPredicting prognosis after stroke: a placebo group analysis from the National Institute of Neurological Disorders and Stroke rt-PA Stroke TrialNeurology200055795295911061250
   PubMed Web of Science ®Google Scholar
• SaposnikGYoungBSilverBLack of improvement in patients with acute stroke after treatment with thrombolytic therapy: predictors and association with outcomeJAMA2004292151839184415494581
   PubMed Web of Science ®Google Scholar
• AwadhMMacDougallNSantoshCTeasdaleEBairdTMuirKWEarly recurrent ischemic stroke complicating intravenous thrombolysis for stroke: incidence and association with atrial fibrillationStroke20104191990199520705933
   PubMed Web of Science ®Google Scholar
• HackeWKasteMFieschiCIntravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: the European cooperative acute Stroke Study (ECASS)J Am Med Assoc199527410171025
   PubMed Web of Science ®Google Scholar
• TrouillasPvon KummerRClassification and pathogenesis of cerebral hemorrhages after thrombolysis in ischemic strokeStroke200637255656116397182
   PubMed Web of Science ®Google Scholar
• BreuerLBlinzlerCHuttnerHBKiphuthICSchwabSKöhrmannMOff-label thrombolysis for acute ischemic stroke: rate, clinical outcome and safety are influenced by the definition of ‘minor stroke’Cerebrovasc Dis201132217718521849777
   PubMed Web of Science ®Google Scholar
• AyHFurieKLSinghalASmithWSSorensenAGKoroshetzWJAn evidence-based causative classification system for acute ischemic strokeAnn Neurol200558568869716240340
   PubMed Web of Science ®Google Scholar
• ArsavaEMBallabioEBennerTThe causative classification of stroke system: an international reliability and optimization studyNeurology201075141277128420921513
   PubMed Web of Science ®Google Scholar
• PexmanJHBarberPAHillMDUse of the Alberta Stroke Program Early CT Score (ASPECTS) for assessing CT scans in patients with acute strokeAJNR Am J Neuroradiol20012281534154211559501
   PubMed Web of Science ®Google Scholar
• WahlgrenNMoreiraTMichelPMechanical thrombectomy in acute ischemic stroke: consensus statement by ESO-Karolinska stroke update 2014/2015, supported by ESO, ESMINT, ESNR and EANInt J Stroke201611113414726763029
   PubMed Web of Science ®Google Scholar
• CasoVMichelPThrombolysis in acute strokeLancet2015385997613951396
   Web of Science ®Google Scholar
• Mayda-DomaçFMisirliHYilmazMPrognostic role of mean platelet volume and platelet count in ischemic and hemorrhagic strokeJ Stroke Cerebrovasc Dis2010191667220123229
   PubMed Web of Science ®Google Scholar
• FlussRFaraggiDReiserBEstimation of the Youden index and its associated cutoff pointBiom J200547445847216161804
   PubMed Web of Science ®Google Scholar
• PowersWJRabinsteinAAAckersonTGuidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/ American Stroke AssociationStroke2018201849e46e110
   Google Scholar
• EmbersonJLeesKRLydenPEffect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trialsLancet201438499581929193525106063
   PubMed Web of Science ®Google Scholar
• WahlgrenNAhmedNErikssonNMultivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring study (SITS-MOST)Stroke200839123316332218927461
   PubMed Web of Science ®Google Scholar
• WhiteleyWNSlotKBFernandesPSandercockPWardlawJRisk factors for intracranial hemorrhage in acute ischemic stroke patients treated with recombinant tissue plasminogen activator: a systematic review and meta-analysis of 55 studiesStroke201243112904290922996959
   PubMed Web of Science ®Google Scholar
• ArikanogluAYucelYAcarACevikMUAkilEVarolSThe relationship of the mean platelet volume and C-reactive protein levels with mortality in ischemic stroke patientsEur Rev Med Pharmacol Sci201317131774177723852903
   PubMed Web of Science ®Google Scholar
• Mayda-DomaçFMisirliHYilmazMPrognostic role of mean platelet volume and platelet count in ischemic and hemorrhagic strokeJ Stroke Cerebrovasc Dis2010191667220123229
   PubMed Web of Science ®Google Scholar
• GreiseneggerSEndlerGHsiehKTentschertSMannhalterCLalouschekWIs elevated mean platelet volume associated with a worse outcome in patients with acute ischemic cerebrovascular events?Stroke20043571688169115143290
   PubMed Web of Science ®Google Scholar
• ButterworthRJBathPMThe relationship between mean platelet volume, stroke subtype and clinical outcomePlatelets19989635936416793719
   PubMed Web of Science ®Google Scholar
• DuJWangQHeBAssociation of mean platelet volume and platelet count with the development and prognosis of ischemic and hemorrhagic strokeInt J Lab Hematol201638323323926992440
   PubMed Web of Science ®Google Scholar
• ElsayedAMMohamedGAMean platelet volume and mean platelet volume/platelet count ratio as a risk stratification tool in the assessment of severity of acute ischemic strokeAlexandria J Med20175316770
   Web of Science ®Google Scholar
• Arévalo-LoridoJCCarretero-GómezJÁlvarez-OlivaAGutiérrez-MontañoCFernández-RecioJMNajarro-DíezFMean platelet volume in acute phase of ischemic stroke, as predictor of mortality and functional outcome after 1 yearJ Stroke Cerebrovasc Dis201322429730322005035
   PubMed Web of Science ®Google Scholar
• MuscariAPudduGMCenniAMean platelet volume (MPV) increase during acute non-lacunar ischemic strokesThromb Res2009123458759118472144
   PubMed Web of Science ®Google Scholar
• CiancarelliIDe AmicisDDi MassimoCPistariniCCiancarelliMGMean platelet volume during ischemic stroke is a potential pro-inflammatory biomarker in the acute phase and during neurorehabilitation not directly linked to clinical outcomeCurr Neurovasc Res201613317718327184032
   PubMed Web of Science ®Google Scholar
• NtaiosGGurerOFaouziMAubertCMichelPMean platelet volume in the early phase of acute ischemic stroke is not associated with severity or functional outcomeCerebrovasc Dis201029548448920299788
   PubMed Web of Science ®Google Scholar
• KamisliOKamisliSKablanYGonulluSOzcanCThe prognostic value of an increased mean platelet volume and platelet distribution width in the early phase of cerebral venous sinus thrombosisClin Appl Thromb Hemost2013191293222815317
   PubMed Web of Science ®Google Scholar
• CaoXXieXZhouJYangPWangYChenZIncreased platelet volume in a general population with prehypertension: a cross-sectional study of 80 545 participants from ChinaHypertens Res201235990390822573201
   PubMed Web of Science ®Google Scholar
• VerdoiaMBarbieriLSchafferAImpact of renal function on mean platelet volume and its relationship with coronary artery disease: a single-centre cohort studyThromb Res201614113914427039166
   PubMed Web of Science ®Google Scholar
• KeatingFKSobelBESchneiderDJEffects of increased concentrations of glucose on platelet reactivity in healthy subjects and in patients with and without diabetes mellitusAm J Cardiol200392111362136514636925
   PubMed Web of Science ®Google Scholar
• PedreñoJHurt-CamejoEWiklundOBadimónLMasanaLLow-density lipoprotein (LDL) binds to a G-protein coupled receptor in human platelets. Evidence that the proaggregatory effect induced by LDL is modulated by down-regulation of binding sites and desensitization of its mediated signalingAtherosclerosis200115519911211223431
   PubMed Web of Science ®Google Scholar
• Arévalo-LoridoJCCarretero-GómezJVillar-VacaPMean platelet volume predicting carotid atherosclerosis in atherothrombotic ischemic strokeIr J Med Sci2012181217918321928050
   PubMed Web of Science ®Google Scholar
• OzIIYucelMBiliciMIs mean platelet volume a reliable marker to predict ischemic stroke in the follow-up of patients with carotid stenosis?J Stroke Cerebrovasc Dis201625240440926576699
   PubMed Web of Science ®Google Scholar
• KokluEYukselIOArslanSPredictors of symptom development in intermediate carotid artery stenosis: mean platelet volume and platelet distribution widthAngiology201667762262926514416
   PubMed Web of Science ®Google Scholar
• O’MalleyTLanghornePEltonRAStewartCPlatelet size in stroke patientsStroke19952669959997762052
   PubMed Web of Science ®Google Scholar
• ColkesenYAcilTAbayliBMean platelet volume is elevated during paroxysmal atrial fibrillation: a marker of increased platelet activation?Blood Coagul Fibrinolysis200819541141418600091
   PubMed Web of Science ®Google Scholar
• PikijaSCvetkoDHajdukMTrkuljaVHigher mean platelet volume determined shortly after the symptom onset in acute ischemic stroke patients is associated with a larger infarct volume on CT brain scans and with worse clinical outcomeClin Neurol Neurosurg2009111756857319446390
   PubMed Web of Science ®Google Scholar
• XuXRCarrimNNevesMAPlatelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapiesThromb J201614Suppl 12927766055
   PubMedGoogle Scholar
• Viera-de-AbreuARondinaMTWeyrichASZimmermannGAThe role of platelets in disease: inflammationMichelsonADPlatelets3rd edNew YorkElsevier Inc2013733766
   Google Scholar
• del ZoppoGJThe role of platelets in disease: central nervous system ischemiaMichelsonADPlatelets3rd edElsevier Inc2013669698
   Google Scholar
• Ho-Tin-NoéBDemersMWagnerDDHow platelets safeguard vascular integrityJ Thromb Haemost20119Suppl 1566521781242
   PubMed Web of Science ®Google Scholar
• FranksZGCampbellRAWeyrichASRondinaMTPlatelet– leukocyte interactions link inflammatory and thromboembolic events in ischemic strokeAnn N Y Acad Sci201012071111720955420
   PubMed Web of Science ®Google Scholar
• TangYHVitalSRussellJSeifertHGrangerDNInterleukin-6 mediates enhanced thrombus development in cerebral arterioles following a brief period of focal brain ischemiaExp Neurol201527135135726054883
   PubMed Web of Science ®Google Scholar
• WelshPLoweGDChalmersJAssociations of proinflammatory cytokines with the risk of recurrent strokeStroke20083982226223018566306
   PubMed Web of Science ®Google Scholar
• CampbellDJWoodwardMChalmersJPSoluble vascular cell adhesion molecule 1 and N-terminal pro-B-type natriuretic peptide in predicting ischemic stroke in patients with cerebrovascular diseaseArch Neurol2006631606516286536
   PubMedGoogle Scholar
• NieswandtBPleinesIBenderMPlatelet adhesion and activation mechanisms in arterial thrombosis and ischaemic strokeJ Thromb Haemost20119Suppl 192104
   PubMed Web of Science ®Google Scholar
• KarlinskiMBembenekJGrabskaKRoutine serum C-reactive protein and stroke outcome after intravenous thrombolysisActa Neurol Scand2014130530531124571644
   PubMed Web of Science ®Google Scholar
• ElkindMSLunaJMMoonYPHigh-sensitivity C-reactive protein predicts mortality but not stroke: the Northern Manhattan StudyNeurology200973161300130719841382
   PubMed Web of Science ®Google Scholar
• Di NapoliMPapaFBocolaVC-reactive protein in ischemic stroke: an independent prognostic factorStroke200132491711283392
   PubMed Web of Science ®Google Scholar
• MatosevicBKnoflachMWernerPFibrinogen degradation coagulopathy and bleeding complications after stroke thrombolysisNeurology201380131216122423486872
   PubMed Web of Science ®Google Scholar
• MontanerJMolinaCAMonasterioJMatrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human strokeCirculation2003107459860312566373
   PubMed Web of Science ®Google Scholar
• Ramos-FernandezMBellolioMFSteadLGMatrix metalloproteinase-9 as a marker for acute ischemic stroke: a systematic reviewJ Stroke Cerebrovasc Dis2011201475421044610
   PubMed Web of Science ®Google Scholar
• KatanMFluriFMorgenthalerNGCopeptin: a novel, independent prognostic marker in patients with ischemic strokeAnn Neurol200966679980820035506
   PubMed Web of Science ®Google Scholar
• Garcia-BerrocosoTGiraltDBustamanteAB-type natriuretic peptides and mortality after stroke: a systematic review and meta-analysisNeurology201381231976198524186915
   PubMed Web of Science ®Google Scholar
• BarberMLanghornePRumleyALoweGDStottDJHemostatic function and progressing ischemic stroke: D-dimer predicts early clinical progressionStroke2004356142115073383
   PubMed Web of Science ®Google Scholar
• del ZoppoGJLevyDEWasiewskiWWHyperfibrinogenemia and functional outcome from acute ischemic strokeStroke20094051687169119299642
   PubMed Web of Science ®Google Scholar
• WelshPBarberMLanghornePAssociations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic strokeCerebrovasc Dis200927324725319176958
   PubMed Web of Science ®Google Scholar
• FoerchCWunderlichMTDvorakFElevated serum S100B levels indicate a higher risk of hemorrhagic transformation after thrombolytic therapy in acute strokeStroke20073892491249517673718
   PubMed Web of Science ®Google Scholar
• KönigIRZieglerABluhmkiEPredicting long-term outcome after acute ischemic stroke: a simple index works in patients from controlled clinical trialsStroke20083961821182618403738
   PubMed Web of Science ®Google Scholar
• BowlesKMCookeLJRichardsEMBaglinTPPlatelet size has diagnostic predictive value in patients with thrombocytopeniaClin Lab Haematol200527637037316307537
   PubMedGoogle Scholar
• MachinSJBriggsCMean platelet volume: a quick, Easy determinant of thrombotic risk?J Thromb Haemost20108114614719874471
   PubMed Web of Science ®Google Scholar