440
Views
79
CrossRef citations to date
0
Altmetric
Review

Effectiveness of influenza vaccine in aging and older adults: comprehensive analysis of the evidence

, , , , &
Pages 55-64 | Published online: 24 Feb 2012

References

  • World Health Organization (WHO)Influenza (Seasonal)Fact sheet N°21142009 [updated 2011]. Available from: http://www.who.int/mediacentre/factsheets/fs211/en/Accessed November 30, 2011
  • Centers for Disease Control and Prevention (CDC)Prevention and Control of Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices (ACIP)MMWR Morb Mortal Wkly Rep201160331128113221866086
  • National Advisory Committee on ImmunizationStatement on seasonal influenza vaccine for 2011–2012Canada Communicable Disease Report (CCDR)201137ACS5155 [updated 2011]. Available from: http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/11vol37/acs-dcc-5/assets/pdf/acs-dcc-5-eng.pdfAccessed October 30, 2011
  • MichielsBGoveartsFRemmenRVermeireECoenenSA systematic review of the evidence on the effectiveness and risks of inactivated influenza vaccines in different target groupsVaccine201129499159917021840359
  • European Centre for Disease Prevention ControlSeasonal human influenza and vaccination [updated 2011]. Available from: http://www.ecdc.europa.eu/en/press/Press%20Releases/071012_PR_SI_Prof_Fact_Sheet.pdfAccessed October 30, 2011
  • MontoASSeasonal influenza and vaccination coverageVaccine201028Suppl 4D334420713259
  • MichelJPLangPOBaeyensJPFlu vaccination policy in old adults: need for harmonization of national public health recommendations throughout EuropeVaccine200927218218319010367
  • ParodiVde FlorentiisDMartiniMAnsaldiFInactivated influenza vaccines: recent progress and implication for the elderlyDrugs Aging20112829310621275435
  • MontoASAnsaldiFAspinallRInfluenza control in the 21st century: optimizing protection for older adultsVaccine200927375043505319559118
  • LangPOGovindSMitchellWASiegristCAAspinallRVaccine effectiveness in older individuals: What has been learned from influenza-vaccine experienceAgeing Res Rev201110338939520888439
  • LangPOGovindSMitchellWAInfluenza vaccine effectiveness in aged individuals: the role played by cell-mediated immunityEur Geriatr Med201012233238
  • SimonsenLTaylorRJViboudCMillerMAJacksonLAMortality benefits of influenza vaccination in elderly people: an ongoing controversyLancet Infect Dis200771065866617897608
  • BeigelJHInfluenzaCrit Care Med20083692660266618679129
  • World Health OrganizationInfluenza vaccinesWkly Epidemiol Rec2005803327928716171031
  • McElhaneyJEThe unmet need in the elderly: designing new influenza vaccines for older adultsVaccine200523Suppl 1S10S2515908062
  • GreenbergHBPiedraPAImmunization against viral respiratory disease: a reviewPediatr Infect Dis J200423Suppl 11S254S26115577581
  • GavazziGKrauseKHAgeing and infectionLancet Infect Dis200221165966612409046
  • BarkerWHBorisuteHCoxCA study of the impact of influenza on the functional status of frail older peopleArch Intern Med199815866456509521230
  • MolinariNAOrtega-SanchezIRMessonierMLThe annual impact of seasonal influenza in the US: measuring disease burden and costsVaccine200725275086509617544181
  • NicholKLNordinJDNelsonDBMulloolyJPHakEEffectiveness of influenza vaccine in the community-dwelling elderlyN Engl J Med2007357141373138117914038
  • DeansGDStiverHGMcElhaneyJEInfluenza vaccines provide diminished protection but are cost-saving in older adultsJ Intern Med2010267222022720175868
  • MaciosekMVSolbergLICoffieldABEdwardsNMGoodmanMJInfluenza vaccination health impact and cost effectiveness among adults aged 50 to 64 and 65 and olderAm J Prev Med2006311727916777545
  • Centers for Disease Control and PreventionRecommendation of the Advisory Committee on Immunization PracticesMMWR Morb Mortal Wkly Rep200453RR–06140
  • JeffersonTDi PietrantonjCRivettiABawazeerGAAl-AnsaryFerroniEVaccines for preventing influenza in healthy adultsCochrane Database Syst Rev2007CD00126917443504
  • GovaertTMThijsCTMasurelNSprengerMJDinantGJKnottnerusJAThe efficacy of influenza vaccination in elderly individuals. A randomized double-blind placebo-controlled trialJAMA199427221166116657966893
  • NelsonJCJacksonMLWeissNSJacksonLANew strategies are needed to improve the accuracy of influenza vaccine effectiveness estimates among seniorJ Clin Epidemiol200962768769419124221
  • JeffersonTRivettiDRivettiARudinMDi PietrantonjCDemicheliVEfficacy and effectiveness of influenza vaccines in elderly people: a systematic reviewLancet200536694921165117416198765
  • JeffersonTDi PietrantonjCAl-AnsaryLAFerroniEThorningSThomasREVaccines for preventing influenza in the elderlyCochrane Database Syst Rev2010CD00487620166072
  • OsterholmMTKelleyNSSommerABelongiaEAEfficacy and effectiveness of influenza vaccines: a systematic review and meta-analysisLancet Infect Dis2011121364422032844
  • RivettiDJeffersonTThomasRVaccines for preventing influenza in the elderlyCochrane Database Syst Rev2006CD00487616856068
  • GrossPAHermogenesAWSacksHSLauJLevandowskiRAThe efficacy of influenza vaccine in elderly persons. A meta-analysis and review of the literatureAnn Intern Med199512375185277661497
  • VuTFarishSJenkinsMKellyHA meta-analysis of effectiveness of influenza vaccine in persons aged 65 years and over living in the communityVaccine20022013–141831183611906772
  • FedsonDSWajdaANicolJPHammondGWKaiserDLRoosLLClinical effectiveness of influenza vaccination in ManitobaJAMA199327016195619618411553
  • LegrandJVerguEFlahaultAReal-time monitoring of the influenza vaccine field effectivenessVaccine20062444–466605661116806607
  • MulloolyJPBennettMDHornbrookMCInfluenza vaccination programs for elderly persons: cost-effectiveness in a health maintenance organizationAnn Intern Med1994121129479527978721
  • NordinJMulloolyJPobleteSInfluenza vaccine effectiveness in preventing hospitalizations and deaths in persons 65 years or older in Minnesota, New York, and Oregon: data from 3 health plansJ Infect Dis2001184666567011517426
  • NicholKLNordinJMulloolyJInfluenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderlyN Engl J Med2003348141322133212672859
  • VoordouwBCvan der LindenPDSimonianSvan der LeiJSturkenboomMCStrickerBHInfluenza vaccination in community-dwelling elderly: impact on mortality and influenza-associated morbidityArch Intern Med200316391089109412742808
  • HakEVerheijTJGrobbeeDENicholKLHoesAWConfounding by indication in non-experimental evaluation of vaccine effectiveness: the example of prevention of influenza complicationsJ Epidemiol Community Health2002561295195512461118
  • HakEBuskensEvan EssenGAClinical effectiveness of influenza vaccination in persons younger than 65 years with high-risk medical conditions: the PRISMA studyArch Intern Med2005165327428015710789
  • HakEHoesAWNordinJNicholKLBenefits of influenza vaccine in US elderly – appreciating issues of confounding, bias and precisionInt J Epidemiol200635380080216618708
  • Vila-CorcolesARodriguezTde DiegoCEffect of influenza vaccine status on winter mortality in Spanish community-dwelling elderly people during 2002–2005 influenza periodsVaccine20072537–386699670717698263
  • SimonsenLViboudCTaylorRJMillerMAJacksonLAInfluenza vaccination and mortality benefits: new insights, new opportunityVaccine200927456300630419840664
  • HottesTSSkowronskiDMHiebertBInfluenza vaccine effectiveness in the elderly based on administrative databases: change in immunization habit as a marker for biasPLoS One201167e2261821818350
  • JacksonLAJacksonMLNelsonJCNeuzilKMWeissNSEvidence of bias in estimates of influenza vaccine effectiveness in seniorsInt J Epidemiol200635233734416368725
  • JacksonLANelsonJCBensonPFunctional status is a confounder of the association of influenza vaccine and risk of all cause mortality in seniorsInt J Epidemiol200635234535216368724
  • JacksonLABenefits of examining influenza vaccine associations outside of influenza seasonAm J Respir Crit Care Med2008178543944018713848
  • JacksonMLNelsonJCWeissNSNeuzilKMBarlowWJacksonLAInfluenza vaccination and risk of community-acquired pneumonia in immunocompetent elderly people: a population-based, nested casecontrol studyLancet2008372963639840518675690
  • SambharaSMcElhaneyJEImmunosenescence and influenza vaccine efficacyCurr Top Microbiol Immunol200933341342919768417
  • McElhaneyJEInfluenza vaccine response in older adultsAgeing Res Rev201110337938821055484
  • GoodwinKViboudCSimonsenLAntibody response to influenza vaccine in the elderly: a quantitative reviewVaccine20062486808681116872725
  • BeyerWEPalacheAMBaljetMMasurelNAntibody induction by influenza vaccines in the elderly: a review of the literatureVaccine1989753853942683459
  • SkowronskiDMTweedSADe SerresGRapid decline of influenza vaccine-induced antibody in the elderly: is it real, or is it relevant?J Infect Dis2008197449050218275271
  • TalbotHKFalseyARThe diagnosis of viral respiratory disease in older adultsClin Infect Dis201050574775120121411
  • EbellMHAlfonsoAA systematic review of clinical decision rules for the diagnosis of influenzaAnn Fam Med201191697721242564
  • NicholKLChallenges in evaluating influenza vaccine effectiveness and the mortality benefits controversyVaccine200927456305631119840665
  • ReichertTSimonsenLShamaAPardoSAFedsonDSMillerMAInfluenza and the winter increase in mortality in the United States, 1959–1999Am J Epidemiol2004160549250215321847
  • FlemingDMCrossKWPannellRSInfluenza and its relationship to circulatory disordersEpidemiol Infect2005133225526215816150
  • YuXTsibaneTMcGrawPANeutralizing antibodies derived from the B cells of 1918 influenza pandemic survivorsNature2008455721253253618716625
  • MillerEHoschlerKHardelidPStanfordEAndrewsNZambonMIncidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological studyLancet201037597201100110820096450
  • LangPOInactivated influenza vaccines: pre-vaccination haemagglutinin-antibody titres influence the vaccine response but not necessarily the vaccine effectivenessDrugs Aging201128650521639411
  • SasakiSHeXSHolmesTHInfluence of prior influenza vaccination on antibody and B-cell responsesPLoS One200838e297518714352
  • OhmitSEPetrieJGCrossRTJohnsonEMontoASInfluenza hemagglutination-inhibition antibody titer as a correlate of vaccine-induced protectionJ Infect Dis2011204121879188521998477
  • FengJGulatiUZhangXAntibody quantity versus quality after influenza vaccinationVaccine200927456358636219840673
  • SasakiSSullivanMNarvaezCFLimited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodiesJ Clin Invest201112183109311921785218
  • JeffersonTInfluenza vaccination: policy versus evidenceBMJ2006333757491291517068038
  • FiremanBLeeJLewisNBembomOvan der LaanMBaxterMInfluenza vaccination and mortality: differentiating vaccine effects from biasAm J Epidemiol2009170565065619625341
  • ThompsonWWMooreMRWeintraubEEstimating influenza-associated deaths in the United StatesAm J Public Health200999Suppl 2S225S23019797736
  • Grubeck-LoebensteinBDella BellaSIorioAMMichelJPPawelecGSolanaRImmunosenescence and vaccine failure in the elderlyAging Clin Exp Res200921320120919571643
  • FulopTPawelecGCastleSLoebMImmunosenescence and vaccination in nursing homeClin Infect Dis200948444344819140756
  • SiegristCAAspinallRB-cell responses to vaccination at the extremes of ageNat Rev Immunol20099318519319240757
  • GovindSLapennaALangPOAspinallRImmunotherapy of immunosenescence: who and how?Open Longev Sci2012 In press
  • LangPOAspinallRImmunosenescence and herd immunity: with an ever increasing aging population do we need to rethink vaccine schedules?Expert Rev Vaccines2012 In press
  • LangPOGovindSMichelJPAspinallRMitchellWAImmunosenescence: Implications for vaccination programmes in adultsMaturitas201168432233021316879
  • ThomasREJeffersonTLassersonTJInfluenza vaccination for healthcare workers who work with the elderlyCochrane Database Syst Rev2010CD00518720166073
  • ThomasREJeffersonTLassersonTJInfluenza vaccination for healthcare workers who work with the elderly: systematic reviewVaccine201029234435620937313
  • LemaitreMMeretTRothan-TondeurMEffect of influenza vaccination of nursing home staff on mortality of residents: a cluster-randomized trialJ Am Geriatr Soc20095791580158619682118
  • HaywardACHarlingRWettenSEffectiveness of an influenza vaccine programme for care home staff to prevent death, morbidity, and health service use among residents: cluster randomised controlled trialBMJ20063337581124117142257
  • CarmanWFElderAGWallaceLAEffects of influenza vaccination of health-care workers on mortality of elderly people in long-term care: a randomised controlled trialLancet20003559198939710675165
  • PotterJStottDJRobertsMAInfluenza vaccination of health care workers in long-term-care hospitals reduces the mortality of elderly patientsJ Infect Dis19971751168985189
  • TalbotTRDellitTHHebdenJSamaDCunyJFactors associated with increased healthcare worker influenza vaccination rates: results from a national survey of university hospitals and medical centersInfect Control Hosp Epidemiol201031545646220233060
  • BlankPRSchwenkglenksMSzucsTDVaccination coverage rates in eleven European countries during two consecutive influenza seasonsJ Infect200958644645819446340
  • WeiskopfDWeinbergerDGrubeck-LoebensteinBThe aging of the immune systemTranspl Int200922111041105019624493