Association Between Polypharmacy, Anxiety, and Depression Among Chinese Older Adults: Evidence from the Chinese Longitudinal Healthy Longevity Survey

References

• Hajjar ER, Cafiero AC, Hanlon JT. Polypharmacy in elderly patients. Am J Geriatr Pharmacother. 2007;5(4):345–351. doi:10.1016/j.amjopharm.2007.12.002
   PubMedGoogle Scholar
• Pazan F, Wehling M. Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences. Eur Geriatr Med. 2021;12(3):443–452. doi:10.1007/s41999-021-00479-3
   PubMed Web of Science ®Google Scholar
• Maher RL, Hanlon J, Hajjar ER. Clinical consequences of polypharmacy in elderly. Expert Opin Drug Saf. 2014;13(1):57–65. doi:10.1517/14740338.2013.827660
   PubMed Web of Science ®Google Scholar
• Eriksen CU, Kyriakidis S, Christensen LD, et al. Medication-related experiences of patients with polypharmacy: a systematic review of qualitative studies. BMJ open. 2020;10(9):e036158–e036158. doi:10.1136/bmjopen-2019-036158
   PubMed Web of Science ®Google Scholar
• Palagyi A, Keay L, Harper J, Potter J, Lindley RI. Barricades and brickwalls–a qualitative study exploring perceptions of medication use and deprescribing in long-term care. BMC Geriatr. 2016;16(1):15. doi:10.1186/s12877-016-0181-x
   PubMed Web of Science ®Google Scholar
• Gutiérrez-Valencia M, Izquierdo M, Cesari M, Casas-Herrero Á, Inzitari M, Martínez-Velilla N. The relationship between frailty and polypharmacy in older people: a systematic review. Br J Clin Pharmacol. 2018;84(7):1432–1444. doi:10.1111/bcp.13590
   PubMed Web of Science ®Google Scholar
• Magnuson A, Sattar S, Nightingale G, Saracino R, et al. A practical guide to geriatric syndromes in older adults with cancer: a focus on falls, cognition, polypharmacy, and depression. Am Soc Clin Oncol Educ Book. 2019;39:e96–e109. doi:10.1200/edbk_237641.
   PubMedGoogle Scholar
• Kornholt J, Christensen MB. Prevalence of polypharmacy in Denmark. Dan Med J. 2020;67(6):Jun.
   Web of Science ®Google Scholar
• Kantor ED, Rehm CD, Haas JS, Chan AT, Giovannucci EL. Trends in prescription drug use among adults in the United States from 1999–2012. JAMA. 2015;314(17):1818–1831. doi:10.1001/jama.2015.13766
   PubMed Web of Science ®Google Scholar
• Page AT, Falster MO, Litchfield M, Pearson SA, Etherton-Beer C. Polypharmacy among older Australians, 2006–2017: a population-based study. Med J Aust. 2019;211(2):71–75. doi:10.5694/mja2.50244
   PubMed Web of Science ®Google Scholar
• Zhang XM, Jiao J, Guo N, Bo HX, Xu T, Wu XJ. Association of polypharmacy with falls among older Chinese inpatients: a nationwide cohort study. Geriatr Gerontol Int. 2021;21(9):810–817. doi:10.1111/ggi.14245
   PubMed Web of Science ®Google Scholar
• Wang R, Chen L, Fan L, et al. Incidence and effects of polypharmacy on clinical outcome among patients aged 80+: a five-year follow-up study. PLoS One. 2015;10(11):e0142123. doi:10.1371/journal.pone.0142123
   PubMed Web of Science ®Google Scholar
• Li J, Chattopadhyay K, Xu M, et al. Prevalence and predictors of polypharmacy prescription among type 2 diabetes patients at a tertiary care department in Ningbo, China: a retrospective database study. PLoS One. 2019;14(7):e0220047–e0220047. doi:10.1371/journal.pone.0220047
   PubMed Web of Science ®Google Scholar
• Rieckert A, Trampisch US, Klaaßen-Mielke R, et al. Polypharmacy in older patients with chronic diseases: a cross-sectional analysis of factors associated with excessive polypharmacy. BMC Fam Pract. 2018;19(1):113. doi:10.1186/s12875-018-0795-5
   PubMed Web of Science ®Google Scholar
• Palapinyo S, Methaneethorn J, Leelakanok N. Association between polypharmacy and depression: a systematic review and meta-analysis. J Pharm Pract Res. 2021;51(4):280–299. doi:10.1002/jppr.1749
   Web of Science ®Google Scholar
• Bazargan M, Smith J, Saqib M, Helmi H, Assari S. Associations between polypharmacy, self-rated health, and depression in African American older adults; mediators and moderators. Int J Environ Res Public Health. 2019;16(9):1574. doi:10.3390/ijerph16091574
   PubMed Web of Science ®Google Scholar
• Choi NG, Marti CN, Kunik ME. Predictors of CNS-active medication use and polypharmacy among homebound older adults with depression. Psychiatr Serv. 2020;71(8):847–850. doi:10.1176/appi.ps.201900551
   PubMed Web of Science ®Google Scholar
• Zhao Y, Zhao S, Zhang L, Haregu TN, Wang H. Impacts of multimorbidity on medication treatment, primary healthcare and hospitalization among middle-aged and older adults in China: evidence from a nationwide longitudinal study. BMC public Health. 2021;21(1):1380. doi:10.1186/s12889-021-11456-7
   PubMed Web of Science ®Google Scholar
• Center for Healthy A, Development S. Data from: the Chinese Longitudinal Healthy Longevity Survey (CLHLS)-longitudinal data (1998–2018). 2020; DRAFT VERSION. Deposited 2020-04-0316:22:09.385. doi:10.18170/DVN/WBO7LK.
   Google Scholar
• Zheng Z. Twenty years’ follow-up on elder people’s health and quality of life. China Popul Dev Stud. 2020;3(4):297–309. doi:10.1007/s42379-020-00045-7
   Google Scholar
• Spitzer RL, Kroenke K, Williams JB, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166(10):1092–1097. doi:10.1001/archinte.166.10.1092
   PubMed Web of Science ®Google Scholar
• Ren Z, Zhou Y, Liu Y. The psychological burden experienced by Chinese citizens during the COVID-19 outbreak: prevalence and determinants. BMC Public Health. 2020;20(1):1617. doi:10.1186/s12889-020-09723-0
   PubMed Web of Science ®Google Scholar
• Niu L, Qiu Y, Luo D, et al. Cross-culture validation of the HIV/AIDS stress scale: the development of a revised Chinese Version. PLoS One. 2016;11(4):e0152990. doi:10.1371/journal.pone.0152990
   PubMed Web of Science ®Google Scholar
• Liu Y, Chen X, Yan Z. Depression in the house: the effects of household air pollution from solid fuel use among the middle-aged and older population in China. Sci Total Environ. 2020;703:134706. doi:10.1016/j.scitotenv.2019.134706
   PubMed Web of Science ®Google Scholar
• Cheng ST, Chan AC. The center for epidemiologic studies depression scale in older Chinese: thresholds for long and short forms. Int J Geriatr Psychiatry. 2005;20(5):465–470. doi:10.1002/gps.1314
   PubMed Web of Science ®Google Scholar
• Masnoon N, Shakib S, Kalisch-Ellett L, Caughey GE. What is polypharmacy? A systematic review of definitions. BMC Geriatr. 2017;17(1):230. doi:10.1186/s12877-017-0621-2
   PubMed Web of Science ®Google Scholar
• Almirall J, Fortin M. The coexistence of terms to describe the presence of multiple concurrent diseases. J Comorb. 2013;3(1):4–9. doi:10.15256/joc.2013.3.22
   PubMedGoogle Scholar
• Midão L, Giardini A, Menditto E, Kardas P, Costa E. Polypharmacy prevalence among older adults based on the survey of health, ageing and retirement in Europe. Arch Gerontol Geriatr. 2018;78:213–220. doi:10.1016/j.archger.2018.06.018
   PubMed Web of Science ®Google Scholar
• Chen C, Feng Z, Fu Q, et al. Predictors of polypharmacy among elderly patients in china: the role of decision involvement, depression, and taking Chinese medicine behavior. Front Pharmacol. 2021;12:745688. doi:10.3389/fphar.2021.745688
   PubMed Web of Science ®Google Scholar
• Hoogendijk EO, Afilalo J, Ensrud KE, Kowal P, Onder G, Fried LP. Frailty: implications for clinical practice and public health. Lancet. 2019;394(10206):1365–1375. doi:10.1016/s0140-6736(19)31786-6
   PubMed Web of Science ®Google Scholar
• Vaughan L, Corbin AL, Goveas JS. Depression and frailty in later life: a systematic review. Clin Interv Aging. 2015;10:1947–1958. doi:10.2147/cia.S69632
   PubMed Web of Science ®Google Scholar
• Mayerl H, Stolz E, Freidl W. Frailty and depression: reciprocal influences or common causes? Soc Sci Med. 2020;263:113273. doi:10.1016/j.socscimed.2020.113273
   PubMed Web of Science ®Google Scholar
• Lotfaliany M, Bowe SJ, Kowal P, Orellana L, Berk M, Mohebbi M. Depression and chronic diseases: co-occurrence and communality of risk factors. J Affect Disord. 2018;241:461–468. doi:10.1016/j.jad.2018.08.011
   PubMed Web of Science ®Google Scholar
• Read JR, Sharpe L, Modini M, Dear BF. Multimorbidity and depression: a systematic review and meta-analysis. J Affect Disord. 2017;221:36–46. doi:10.1016/j.jad.2017.06.009
   PubMed Web of Science ®Google Scholar
• Trivedi MH. The link between depression and physical symptoms. Prim Care Companion J Clin Psychiatry. 2004;6(Suppl 1):12–16.
   PubMedGoogle Scholar
• Assari S, Bazargan M. Polypharmacy and psychological distress may be associated in African American adults. Pharmacy. 2019;7(1). doi:10.3390/pharmacy7010014
   Web of Science ®Google Scholar
• Fountoulakis KN, Grunze H, Vieta E, et al. The International College of Neuro-Psychopharmacology (CINP) treatment guidelines for Bipolar Disorder in adults (CINP-BD-2017), Part 3: the clinical guidelines. Int J Neuropsychopharmacol. 2017;20(2):180–195. doi:10.1093/ijnp/pyw109
   PubMed Web of Science ®Google Scholar
• Aw JYH, Yiengprugsawan VS, Gong CH. Utilization of traditional Chinese medicine practitioners in later life in Mainland China. Geriatrics. 2019;4(3):49. doi:10.3390/geriatrics4030049
   PubMed Web of Science ®Google Scholar
• Yang Z, Zhu Z, Lizarondo L, et al. Experience of chronic noncommunicable disease in people living with HIV: a systematic review and meta-aggregation of qualitative studies. BMC Public Health. 2021;21(1):1651. doi:10.1186/s12889-021-11698-5
   PubMed Web of Science ®Google Scholar