Relationship Between Preoperative Hypoalbuminemia and Postoperative Pneumonia Following Geriatric Hip Fracture Surgery: A Propensity-Score Matched and Conditional Logistic Regression Analysis

References

• Lo I, Siu C, Tse H, Lau T, Leung F, Wong M. Pre-operative pulmonary assessment for patients with hip fracture. Osteoporos Int. 2010;21:S579–86. doi:10.1007/s00198-010-1427-7
   PubMed Web of Science ®Google Scholar
• Shin K, Kim J, Son S, Hwang K, Han S. Early postoperative hypoalbuminaemia as a risk factor for postoperative pneumonia following hip fracture surgery. Clin Interv Aging. 2020;15:1907–1915. doi:10.2147/cia.S272610
   PubMed Web of Science ®Google Scholar
• Xiang G, Dong X, Xu T, et al. A nomogram for prediction of postoperative pneumonia risk in elderly hip fracture patients. Risk Manag Healthc Policy. 2020;13:1603–1611. doi:10.2147/rmhp.S270326
   PubMed Web of Science ®Google Scholar
• Chatterton BD, Moores TS, Ahmad S, Cattell A, Roberts PJ. Cause of death and factors associated with early in-hospital mortality after hip fracture. Bone Joint J. 2015;97-B(2):246–251. doi:10.1302/0301-620X.97B2.35248
   PubMed Web of Science ®Google Scholar
• Lv H, Yin P, Long A, et al. Clinical characteristics and risk factors of postoperative pneumonia after hip fracture surgery: a pr ospective cohort study. Osteoporos Int. 2016;27(10):3001–3009. doi:10.1007/s00198-016-3624-5
   PubMed Web of Science ®Google Scholar
• Salarbaks AM, Lindeboom R, Nijmeijer W. Pneumonia in hospitalized elderly hip fracture patients: the effects on length of hospital-stay, in-h ospital and thirty-day mortality and a search for potential predictors. Injury. 2020;51(8):1846–1850. doi:10.1016/j.injury.2020.05.017
   PubMed Web of Science ®Google Scholar
• Tarazona-Santabalbina F, Belenguer-Varea A, Rovira-Daudi E, et al. Early interdisciplinary hospital intervention for elderly patients with hip fractures: functional outcome and mortality. Clinics. 2012;67(6):547–556. doi:10.6061/clinics/2012(06)02
   PubMed Web of Science ®Google Scholar
• Bohl DD, Sershon RA, Saltzman BM, Darrith B, Della Valle CJ. Incidence, risk factors, and clinical implications of pneumonia after surgery for geriatric hip fract ure. J Arthroplasty. 2018;33(5):1552–1556.e1. doi:10.1016/j.arth.2017.11.068
   PubMed Web of Science ®Google Scholar
• Kamath A, Nelson C, Elkassabany N, Guo Z, Liu J. Low albumin is a risk factor for complications after revision total knee arthroplasty. J Knee Surg. 2017;30(3):269–275. doi:10.1055/s-0036-1584575
   PubMed Web of Science ®Google Scholar
• Koren-Hakim T, Weiss A, Hershkovitz A, et al. Comparing the adequacy of the MNA-SF, NRS-2002 and MUST nutritional tools in assessing malnutrition in hip fracture operated elderly patients. Clinical Nutrition. 2017;36(3):912. doi:10.1016/j.clnu.2017.01.018
   PubMed Web of Science ®Google Scholar
• Lee H, Chang Y, Jean Y, Wang H. Importance of serum albumin level in the preoperative tests conducted in elderly patients with hip fracture. Injury. 2009;40(7):756–759. doi:10.1016/j.injury.2009.01.008
   PubMed Web of Science ®Google Scholar
• Velanovich V. The value of routine preoperative laboratory testing in predicting postoperative complications: a multivariate analysis. Surgery. 1991;109:236–243.
   PubMed Web of Science ®Google Scholar
• Koren-Hakim T, Weiss A, Hershkovitz A, et al. The relationship between nutritional status of hip fracture operated elderly patients and their functioning, comorbidity and outcome. Clinical Nutrition. 2012;31(6):917–921. doi:10.1016/j.clnu.2012.03.010
   PubMed Web of Science ®Google Scholar
• Patterson B, Cornell C, Carbone B, Levine B, Chapman D. Protein depletion and metabolic stress in elderly patients who have a fracture of the hip. J Bone Joint Surg Am. 1992;74(2):251–260. doi:10.2106/00004623-199274020-00011
   PubMed Web of Science ®Google Scholar
• Bohl D, Shen M, Hannon C, Fillingham Y, Darrith B, Della Valle C. Serum albumin predicts survival and postoperative course following surgery for geriatric hip fracture. J Bone Joint Surg Am. 2017;99(24):2110–2118. doi:10.2106/jbjs.16.01620
   PubMed Web of Science ®Google Scholar
• Wang Y, Li X, Ji Y, et al. Preoperative serum albumin level as a predictor of postoperative pneumonia after femoral neck fractur e surgery in a geriatric population. Clin Interv Aging. 2019 14:2007–2016.
   PubMed Web of Science ®Google Scholar
• Ai S, Sun F, Liu Z, et al. Change in serum albumin level predicts short-term complications in patients with normal preoperative serum albumin after gastrectomy of gastric cancer. ANZ J Surg. 2019;89:E297–E301. doi:10.1111/ans.15363
   PubMed Web of Science ®Google Scholar
• Wierdak M, Pisarska M, Kuśnierz-Cabala B, et al. Changes in plasma albumin levels in early detection of infectious complications after laparoscopic colorectal cancer surgery with ERAS protocol. Surg Endosc. 2018;32(7):3225–3233. doi:10.1007/s00464-018-6040-4
   PubMed Web of Science ®Google Scholar
• Li P, Li J, Lai Y, et al. Perioperative changes of serum albumin are a predictor of postoperative pulmonary complications in lung cancer patients: a retrospective cohort study. J Thorac Dis. 2018;10(10):5755–5763. doi:10.21037/jtd.2018.09.113
   PubMed Web of Science ®Google Scholar
• Bicciré F, Pastori D, Tanzilli A, et al. Low serum albumin levels and in-hospital outcomes in patients with ST segment elevation myocardial infarction. Nutr Metab Cardiovasc Dis. 2021;31:2904–2911. doi:10.1016/j.numecd.2021.06.003
   PubMed Web of Science ®Google Scholar
• Akirov A, Masri-Iraqi H, Atamna A, Shimon I. Low albumin levels are associated with mortality risk in hospitalized patients. Am J Med. 2017;130(12):1465.e11–1465.e19. doi:10.1016/j.amjmed.2017.07.020
   PubMed Web of Science ®Google Scholar
• Kalil A, Metersky M, Klompas M, et al. Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the infectious diseases society of America and the American thoracic society. Clin Infect Dis. 2016;63(5):e61–e111. doi:10.1093/cid/ciw353
   PubMed Web of Science ®Google Scholar
• Franch-Arcas G. The meaning of hypoalbuminaemia in clinical practice. Clinical Nutrition. 2001;20(3):265–269. doi:10.1054/clnu.2001.0438
   PubMed Web of Science ®Google Scholar
• Kim S, McClave S, Martindale R, Miller K, Hurt R. Hypoalbuminemia and clinical outcomes: what is the mechanism behind the relationship? Am Surg. 2017;83(11):1220–1227. doi:10.1177/000313481708301123
   PubMed Web of Science ®Google Scholar
• Ballmer PE. Causes and mechanisms of hypoalbuminaemia. Clin Nutr. 2001;20(3):271–273. doi:10.1054/clnu.2001.0439
   PubMed Web of Science ®Google Scholar
• Sim SD, Sim YE, Tay K, et al. Preoperative hypoalbuminemia: poor functional outcomes and quality of life after hip fracture surgery. Bone. 2021;143:115567. doi:10.1016/j.bone.2020.115567
   PubMed Web of Science ®Google Scholar
• Hur E, Bohl D, Della Valle C, Villalobos F, Gerlinger T. Hypoalbuminemia predicts adverse events following unicompartmental knee arthroplasty. J Knee Surg. 2021. doi:10.1055/s-0041-1739146
   PubMed Web of Science ®Google Scholar
• Tan Y, Jiang L, Liu H, Pan Z, Wang H, Chen L. The effect of preoperative hypoalbuminemia on complications after primary hip arthroplasty. J Orthop Surg Res. 2021;16(1):562. doi:10.1186/s13018-021-02702-0
   PubMed Web of Science ®Google Scholar
• Byun S, Shon H, Kim J, Kim H, Sim Y. Risk factors and prognostic implications of aspiration pneumonia in older hip fracture patients: a multicenter retrospective analysis. Geriatr Gerontol Int. 2019;19(2):119–123. doi:10.1111/ggi.13559
   PubMed Web of Science ®Google Scholar
• Higashikawa T, Shigemoto K, Goshima K, et al. Risk factors for the development of aspiration pneumonia in elderly patients with femoral neck and trochanteric fractures: a retrospective study of a patient cohort. Medicine. 2020;99(7):e19108. doi:10.1097/md.0000000000019108
   PubMed Web of Science ®Google Scholar
• Weimann A, Braga M, Carli F, et al. ESPEN guideline: clinical nutrition in surgery. Clin Nutr. 2017;36(3):623–650. doi:10.1016/j.clnu.2017.02.013
   PubMed Web of Science ®Google Scholar
• Lee S, Yeom S, Kim C, Kim H. Effect of preoperative immunonutrition on outcomes of colon cancer surgery: study protocol for a randomized controlled trial. Trials. 2020;21(1):628. doi:10.1186/s13063-020-04544-3
   PubMed Web of Science ®Google Scholar
• Aida T, Furukawa K, Suzuki D, et al. Preoperative immunonutrition decreases postoperative complications by modulating prostaglandin E2 production and T-cell differentiation in patients undergoing pancreatoduodenectomy. Surgery. 2014;155(1):124–133. doi:10.1016/j.surg.2013.05.040
   PubMed Web of Science ®Google Scholar
• Yokoyama K, Ukai T, Watanabe M. Effect of nutritional status before femoral neck fracture surgery on postoperative outcomes: a retrospective study. BMC Musculoskelet Disord. 2021;22(1):1027. doi:10.1186/s12891-021-04913-2
   PubMed Web of Science ®Google Scholar
• Malafarina V, Reginster J, Cabrerizo S, et al. Nutritional status and nutritional treatment are related to outcomes and mortality in older adults with hip fracture. Nutrients. 2018;10(5):555. doi:10.3390/nu10050555
   PubMed Web of Science ®Google Scholar
• Eneroth M, Olsson UB, Thorngren KG. Nutritional supplementation decreases hip fracture-related complications. Clin Orthop Relat Res. 2006;451:212–217. doi:10.1097/01.blo.0000224054.86625.06
   PubMed Web of Science ®Google Scholar