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Clinical Interventions in Aging Volume 17, 2022 - Issue
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Original Research

The Association Between Systemic Immune-Inflammation Index and Postoperative Cognitive Decline in Elderly Patients

Wenbin Lu1 Faculty of Anesthesiology, Changhai Hospital, Naval Medical University/Second Military Medical University, PLA, Shanghai, 200433, People’s Republic of ChinaView further author information
,
Keqin Zhang1 Faculty of Anesthesiology, Changhai Hospital, Naval Medical University/Second Military Medical University, PLA, Shanghai, 200433, People’s Republic of China;2 Department of Anesthesiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, People’s Republic of ChinaView further author information
,
Xinning Chang1 Faculty of Anesthesiology, Changhai Hospital, Naval Medical University/Second Military Medical University, PLA, Shanghai, 200433, People’s Republic of ChinaView further author information
,
Xiya Yu1 Faculty of Anesthesiology, Changhai Hospital, Naval Medical University/Second Military Medical University, PLA, Shanghai, 200433, People’s Republic of ChinaCorrespondence[email protected] [email protected]
View further author information
&
Jinjun Bian1 Faculty of Anesthesiology, Changhai Hospital, Naval Medical University/Second Military Medical University, PLA, Shanghai, 200433, People’s Republic of ChinaView further author information
Pages 699-705 | Published online: 03 May 2022

References

  • Wei P, Yang F, Zheng Q, Tang W, Li J. The Potential Role of the NLRP3 Inflammasome Activation as a Link Between Mitochondria ROS Generation and Neuroinflammation in Postoperative Cognitive Dysfunction. Front Cell Neurosci. 2019;13:73.
  • Evered L, Silbert B, Knopman D, et al. Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018. Br J Anaesth. 2018;121(5):1005–1012.
  • Skvarc D, Berk M, Byrne L, et al. Post-Operative Cognitive Dysfunction: an exploration of the inflammatory hypothesis and novel therapies. Neurosci Biobehavioral Rev. 2018;84:116–133.
  • Deng Y, Wang R, Li S, et al. Methylene blue reduces incidence of early postoperative cognitive disorders in elderly patients undergoing major non-cardiac surgery: an open-label randomized controlled clinical trial. J Clin Anesth. 2021;68:110108.
  • Liu Q, Sun Y, Huang H, et al. Sirtuin 3 protects against anesthesia/surgery-induced cognitive decline in aged mice by suppressing hippocampal neuroinflammation. J Neuroinflammation. 2021;18(1):41.
  • Alam A, Hana Z, Jin Z, Suen K, Ma D. Surgery, neuroinflammation and cognitive impairment. EBioMedicine. 2018;37:547–556.
  • Hu J, Feng X, Valdearcos M, et al. Interleukin-6 is both necessary and sufficient to produce perioperative neurocognitive disorder in mice. Br J Anaesth. 2018;120(3):537–545.
  • Zheng J, Meng B, Li X, Lu B, Wu G, Chen J. NF-κB/P65 signaling pathway: a potential therapeutic target in postoperative cognitive dysfunction after sevoflurane anesthesia. Eur Rev Med Pharmacol Sci. 2017;21(2):394–407.
  • Wang P, Velagapudi R, Kong C, et al. Neurovascular and immune mechanisms that regulate postoperative delirium superimposed on dementia. Alzheimer’s Dementia. 2020;16(5):734–749.
  • Wen C, Xie T, Pan K, et al. Acetate attenuates perioperative neurocognitive disorders in aged mice. Aging. 2020;12(4):3862–3879.
  • Feng X, Valdearcos M, Uchida Y, Lutrin D, Maze M, Koliwad S. Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice. JCI Insight. 2017;2(7):e91229.
  • Yang T, Velagapudi R, Terrando N. Neuroinflammation after surgery: from mechanisms to therapeutic targets. Nat Immunol. 2020;21(11):1319–1326.
  • Jomrich G, Paireder M, Kristo I, et al. High Systemic Immune-Inflammation Index is an Adverse Prognostic Factor for Patients With Gastroesophageal Adenocarcinoma. Ann Surg. 2021;273(3):532–541.
  • Yang Y, Wu C, Hsu P, et al. Systemic immune-inflammation index (SII) predicted clinical outcome in patients with coronary artery disease. Eur J Clin Invest. 2020;50(5):e13230.
  • Li Y, Huang H, Le Y. Risk factors and predictive value of perioperative neurocognitive disorders in elderly patients with gastrointestinal tumors. BMC Anesthesiol. 2021;21(1):193.
  • Kim H, Jung W, Chan Shin Y, et al. The diagnostic and prognostic values of inflammatory markers in intraductal papillary mucinous neoplasm. HPB. 2021;1:w54.
  • Inouye S, Westendorp R, Saczynski J. Delirium in elderly people. Lancet. 2014;383(9920):911–922.
  • Chen R, Zhang X, Gu L, et al. New Insight Into Neutrophils: a Potential Therapeutic Target for Cerebral Ischemia. Front Immunol. 2021;12:692061.
  • Tsukita K, Sakamaki-Tsukita H, Takahashi R. Lower Circulating Lymphocyte Count Predicts ApoE ε4-Related Cognitive Decline in Parkinson’s Disease. Movement Disorder. 2021;1:5.
  • Berger M, Murdoch D, Staats J, et al. Flow Cytometry Characterization of Cerebrospinal Fluid Monocytes in Patients With Postoperative Cognitive Dysfunction: a Pilot Study. Anesth Analg. 2019;129(5):e150–e154.
  • Yu H, Liu Y, He B, et al. Platelet biomarkers for a descending cognitive function: a proteomic approach. Aging Cell. 2021;20(5):e13358.
  • Bartl T, Bekos C, Postl M, et al. The systemic immune-inflammation index (SII) is an independent prognostic parameter of survival in patients with invasive vulvar cancer. J Gynecol Oncol. 2021;32(1):e1.

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