Benefits of Endovascular Treatment in Late Window for Acute Ischemic Stroke Selected without CT Perfusion: A Real-World Study

References

• Albers GW, Marks MP, Kemp S, et al. Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging. New Engl J Med. 2018;378(8):708–718. doi:10.1056/NEJMoa1713973
   PubMed Web of Science ®Google Scholar
• Nogueira RG, Jadhav AP, Haussen DC, et al. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med. 2018;378(1):11–21. doi:10.1056/NEJMoa1706442
   PubMed Web of Science ®Google Scholar
• Powers WJ, Rabinstein AA, Ackerson T, et al. 2018 guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2018;49(3):e46–e110. doi:10.1161/STR.0000000000000158
   PubMed Web of Science ®Google Scholar
• Bouslama M, Haussen DC, Rodrigues G, Barreira C, Frankel M, Nogueira RG. Novel selection paradigms for endovascular stroke treatment in the extended time window. J Neurol Neurosurg Psychiatry. 2021;92(11):1152–1157. doi:10.1136/jnnp-2020-325284
   PubMed Web of Science ®Google Scholar
• Desai SM, Haussen DC, Aghaebrahim A, et al. Thrombectomy 24 hours after stroke: beyond Dawn. J Neurointerv Surg. 2018;10(11):1039–1042. doi:10.1136/neurintsurg-2018-013923
   PubMed Web of Science ®Google Scholar
• Desai SM, Rocha M, Molyneaux BJ, et al. Thrombectomy 6–24 hours after stroke in trial ineligible patients. J Neurointerv Surg. 2018;10(11):1033–1037. doi:10.1136/neurintsurg-2018-013915
   PubMed Web of Science ®Google Scholar
• Herzberg M, Scherling K, Stahl R, et al. Late thrombectomy in clinical practice: retrospective application of dawn/DEFUSE3 criteria within the German stroke registry. Clin Neuroradiol. 2021;31(3):799–810. doi:10.1007/s00062-021-01033-1
   PubMed Web of Science ®Google Scholar
• Sanelli PC, Pandya A, Segal AZ, et al. Cost-effectiveness of CT angiography and perfusion imaging for delayed cerebral ischemia and vasospasm in aneurysmal subarachnoid hemorrhage. AJNR Am J Neuroradiol. 2014;35(9):1714–1720. doi:10.3174/ajnr.A3947
   PubMed Web of Science ®Google Scholar
• Goyal M, Demchuk AM, Menon BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015;372(11):1019–1030. doi:10.1056/NEJMoa1414905
   PubMed Web of Science ®Google Scholar
• Casetta I, Fainardi E, Saia V, et al. Endovascular thrombectomy for acute ischemic stroke beyond 6 hours from onset: a real-world experience. Stroke. 2020;51(7):2051–2057. doi:10.1161/STROKEAHA.119.027974
   PubMed Web of Science ®Google Scholar
• Jung S, Gralla J, Fischer U, et al. Safety of endovascular treatment beyond the 6-h time window in 205 patients. Eur J Neurol. 2013;20(6):865–871. doi:10.1111/ene.12069
   PubMed Web of Science ®Google Scholar
• Beaulieu M-C, Nehme A, Fortin F, et al. Non-contrast CT and CT-angiogram for late window ischemic stroke treatment selection. Can J Neurol Sci. 2020;47(3):309–313. doi:10.1017/cjn.2020.15
   PubMed Web of Science ®Google Scholar
• Dekker L, Venema E, Pirson FAV, et al. Endovascular treatment in anterior circulation stroke beyond 6.5 hours after onset or time last seen well: results from the MR CLEAN Registry. Stroke Vasc Neurol. 2021;6(4):572–580. doi:10.1136/svn-2020-000803
   PubMedGoogle Scholar
• Rocha M, Jovin TG. Fast versus slow progressors of infarct growth in large vessel occlusion stroke: clinical and research implications. Stroke. 2017;48(9):2621–2627. doi:10.1161/STROKEAHA.117.017673
   PubMed Web of Science ®Google Scholar
• Tan IYL, Demchuk AM, Hopyan J, et al. CT angiography clot burden score and collateral score: correlation with clinical and radiologic outcomes in acute middle cerebral artery infarct. AJNR Am J Neuroradiol. 2009;30(3):525–531. doi:10.3174/ajnr.A1408
   PubMed Web of Science ®Google Scholar
• Hacke W, Kaste M, Bluhmki E, et al. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008;359(13):1317–1329. doi:10.1056/NEJMoa0804656
   PubMed Web of Science ®Google Scholar
• Austin PC. Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples. Stat Med. 2009;28(25):3083–3107. doi:10.1002/sim.3697
   PubMed Web of Science ®Google Scholar
• Jovin TG, Nogueira RG, Lansberg MG, et al. Thrombectomy for anterior circulation stroke beyond 6 h from time last known well (Aurora): a systematic review and individual patient data meta-analysis. Lancet. 2022;399(10321):249–258. doi:10.1016/S0140-6736(21)01341-6
   PubMed Web of Science ®Google Scholar
• Huang Q, Gu M, Zhou J, et al. Endovascular treatment of acute ischemic stroke due to anterior circulation large vessel occlusion beyond 6 hours: a real-world study in China. BMC Neurol. 2021;21(1):92. doi:10.1186/s12883-021-02122-x
   PubMed Web of Science ®Google Scholar
• Alexandre AM, Pedicelli A, Valente I, et al. May endovascular thrombectomy without CT perfusion improve clinical outcome? Clin Neurol Neurosurg. 2020;198:106207. doi:10.1016/j.clineuro.2020.106207
   PubMed Web of Science ®Google Scholar
• Tsurukiri J, Ota T, Jimbo H, et al. Thrombectomy for stroke at 6–24 hours without perfusion CT software for patient selection. J Stroke Cerebrovasc Dis. 2019;28(3):774–781. doi:10.1016/j.jstrokecerebrovasdis.2018.11.022
   PubMed Web of Science ®Google Scholar
• Beckhauser MT, Castro-Afonso LH, Dias FA, et al. Extended time window mechanical thrombectomy for acute stroke in Brazil. J Stroke Cerebrovasc Dis. 2020;29(10):105134. doi:10.1016/j.jstrokecerebrovasdis.2020.105134
   PubMed Web of Science ®Google Scholar
• Nannoni S, Strambo D, Sirimarco G, et al. Eligibility for late endovascular treatment using Dawn, DEFUSE-3, and more liberal selection criteria in a stroke center. J Neurointerv Surg. 2020;12(9):842–847. doi:10.1136/neurintsurg-2019-015382
   PubMed Web of Science ®Google Scholar
• Santos T, Carvalho A, Cunha AA, et al. NCCT and CTA-based imaging protocol for endovascular treatment selection in late presenting or wake-up strokes. J Neurointerv Surg. 2019;11(2):200–203. doi:10.1136/neurintsurg-2018-014051
   PubMedGoogle Scholar
• Bücke P, Pérez MA, Hellstern V, AlMatter M, Bäzner H, Henkes H. Endovascular thrombectomy in wake-up stroke and stroke with unknown symptom onset. AJNR Am J Neuroradiol. 2018;39(3):494–499.
   PubMed Web of Science ®Google Scholar
• Mehta RH, Cox M, Smith EE, et al. Race/Ethnic differences in the risk of hemorrhagic complications among patients with ischemic stroke receiving thrombolytic therapy. Stroke. 2014;45(8):2263–2269. doi:10.1161/STROKEAHA.114.005019
   PubMed Web of Science ®Google Scholar
• Nakajo Y, Zhao Q, Enmi J-I, et al. Early Detection of Cerebral Infarction After Focal Ischemia Using a New MRI Indicator. Mol Neurobiol. 2019;56(1):658–670. doi:10.1007/s12035-018-1073-1
   PubMed Web of Science ®Google Scholar
• Zaidi SF, Aghaebrahim A, Urra X, et al. Final infarct volume is a stronger predictor of outcome than recanalization in patients with proximal middle cerebral artery occlusion treated with endovascular therapy. Stroke. 2012;43(12):3238–3244. doi:10.1161/STROKEAHA.112.671594
   PubMed Web of Science ®Google Scholar
• Haussen DC, Dehkharghani S, Rangaraju S, et al. Automated CT perfusion ischemic core volume and noncontrast CT ASPECTS (Alberta stroke program early CT score): correlation and clinical outcome prediction in large vessel stroke. Stroke. 2016;47(9):2318–2322. doi:10.1161/STROKEAHA.116.014117
   PubMed Web of Science ®Google Scholar
• Voleti S, Vidovich J, Corcoran B, et al. Correlation of Alberta stroke program early computed tomography score with computed tomography perfusion core in large vessel occlusion in delayed time windows. Stroke. 2021;52(2):498–504. doi:10.1161/STROKEAHA.120.030353
   PubMed Web of Science ®Google Scholar
• Naylor J, Churilov L, Chen Z, Koome M, Rane N, Campbell BCV. Reliability, reproducibility and prognostic accuracy of the Alberta stroke program early CT score on CT perfusion and non-contrast CT in hyperacute stroke. Cerebrovascular Diseases. 2017;44(3–4):195–202. doi:10.1159/000479707
   PubMed Web of Science ®Google Scholar
• Kim B, Jung C, Nam HS, et al. Comparison between perfusion- and collateral-based triage for endovascular thrombectomy in a late time window. Stroke. 2019;50(12):3465–3470. doi:10.1161/STROKEAHA.119.027216
   PubMed Web of Science ®Google Scholar
• Bonnin P, Kubis N, Charriaut-Marlangue C. Collateral supply in preclinical cerebral stroke models. Transl Stroke Res. 2021. doi:10.1007/s12975-021-00969-3
   PubMed Web of Science ®Google Scholar
• Potreck A, Weyland CS, Seker F, et al. Accuracy and prognostic role of NCCT-ASPECTS depend on time from acute stroke symptom-onset for both human and machine-learning based evaluation. Clin Neuroradiol. 2021. doi:10.1007/s00062-021-01110-5
   Web of Science ®Google Scholar
• Regenhardt RW, González RG, He J, Lev MH, Singhal AB. Symmetric CTA collaterals identify patients with slow-progressing stroke likely to benefit from late thrombectomy. Radiology. 2022;302(2):400–407. doi:10.1148/radiol.2021210455
   PubMed Web of Science ®Google Scholar
• Pirson FAVA, Hinsenveld WH, Goldhoorn R-JB, et al. MR CLEAN-LATE, a multicenter randomized clinical trial of endovascular treatment of acute ischemic stroke in The Netherlands for late arrivals: study protocol for a randomized controlled trial. Trials. 2021;22(1):160. doi:10.1186/s13063-021-05092-0
   PubMed Web of Science ®Google Scholar