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REVIEW

Geriatric Health Care During the COVID-19 Pandemic: Managing the Health Crisis

ORCID Icon, &
Pages 1365-1378 | Received 28 May 2022, Accepted 20 Aug 2022, Published online: 13 Nov 2023

References

  • World Health Organization. WHO coronavirus (COVID-19) dashboard; 2022.
  • Gao YD, Ding M, Dong X, et al. Risk factors for severe and critically ill COVID-19 patients: a review. Allergy. 2021;76(2):428–455. doi:10.1111/all.14657
  • Zhang JJ, Cao YY, Tan G, et al. Clinical, radiological, and laboratory characteristics and risk factors for severity and mortality of 289 hospitalized COVID-19 patients. Allergy. 2021;76(2):533–550. doi:10.1111/all.14496
  • Richardson S, Hirsch JS, Narasimhan M, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City Area. JAMA. 2020;323(20):2052–2059. doi:10.1001/jama.2020.6775
  • Remuzzi A, Remuzzi G. COVID-19 and Italy: what next? Lancet. 2020;395(10231):1225–1228. doi:10.1016/s0140-6736(20)30627-9
  • CDC Weekly C; The Novel Coronavirus Pneumonia Emergency Response Epidemiology T. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) - China, 2020. China CDC Wkly. 2020;2(8):113–122. doi:10.46234/ccdcw2020.032
  • Lithander FE, Neumann S, Tenison E, et al. COVID-19 in older people: a rapid clinical review. Age Ageing. 2020;49(4):501–515. doi:10.1093/ageing/afaa093
  • Chen Y, Klein SL, Garibaldi BT, et al. Aging in COVID-19: vulnerability, immunity and intervention. Ageing Res Rev. 2021;65:101205. doi:10.1016/j.arr.2020.101205
  • Wilder-Smith A, Freedman DO. Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak. J Travel Med. 2020;27(2). doi:10.1093/jtm/taaa020
  • Batsis JA, Daniel K, Eckstrom E, et al. Promoting healthy aging during COVID-19. J Am Geriatr Soc. 2021;69(3):572–580. doi:10.1111/jgs.17035
  • Beckman AL, Mechanic RE, Shah TB, Figueroa JF. Accountable Care Organizations during Covid-19: routine care for older adults with multiple chronic conditions. Healthc. 2021;9(1):100511. doi:10.1016/j.hjdsi.2020.100511
  • Promislow DEL. A geroscience perspective on COVID-19 mortality. J Gerontol a Biol Sci Med Sci. 2020;75(9):e30–e33. doi:10.1093/gerona/glaa094
  • Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382(18):1708–1720. doi:10.1056/NEJMoa2002032
  • Ajebli M, Amssayef A, Akdad M, et al. Chronic Diseases and COVID-19: a Review. Endocr Metab Immune Disord Drug Targets. 2021;21(10):1781–1803. doi:10.2174/1871530320666201201110148
  • Summers KL, Marleau AM, Mahon JL, McManus R, Hramiak I, Singh B. Reduced IFN-alpha secretion by blood dendritic cells in human diabetes. Clin Immunol. 2006;121(1):81–89. doi:10.1016/j.clim.2006.05.015
  • van Crevel R, van de Vijver S, Moore DAJ. The global diabetes epidemic: what does it mean for infectious diseases in tropical countries? Lancet Diabetes Endocrinol. 2017;5(6):457–468. doi:10.1016/s2213-8587(16)30081-x
  • Zhu L, She ZG, Cheng X, et al. Association of blood glucose control and outcomes in patients with COVID-19 and pre-existing type 2 diabetes. Cell Metab. 2020;31(6):1068–1077.e3. doi:10.1016/j.cmet.2020.04.021
  • Kolahian S, Leiss V, Nürnberg B. Diabetic lung disease: fact or fiction? Rev Endocr Metab Disord. 2019;20(3):303–319. doi:10.1007/s11154-019-09516-w
  • Rajpal A, Rahimi L, Ismail-Beigi F. Factors leading to high morbidity and mortality of COVID-19 in patients with type 2 diabetes. J Diabetes. 2020;12(12):895–908. doi:10.1111/1753-0407.13085
  • Russell B, Moss C, George G, et al. Associations between immune-suppressive and stimulating drugs and novel COVID-19-a systematic review of current evidence. Ecancermedicalscience. 2020;14:1022. doi:10.3332/ecancer.2020.1022
  • Chung MK, Zidar DA, Bristow MR, et al. COVID-19 and cardiovascular disease: from bench to bedside. Circ Res. 2021;128(8):1214–1236. doi:10.1161/circresaha.121.317997
  • Lely AT, Hamming I, van Goor H, Navis GJ. Renal ACE2 expression in human kidney disease. J Pathol. 2004;204(5):587–593. doi:10.1002/path.1670
  • Borgoni S, Kudryashova KS, Burka K, de Magalhães JP. Targeting immune dysfunction in aging. Ageing Res Rev. 2021;70:101410. doi:10.1016/j.arr.2021.101410
  • McElhaney JE. Influenza vaccine responses in older adults. Ageing Res Rev. 2011;10(3):379–388. doi:10.1016/j.arr.2010.10.008
  • Dock JN, Effros RB. Role of CD8 T cell replicative senescence in human aging and in HIV-mediated immunosenescence. Aging Dis. 2011;2(5):382–397.
  • Ostan R, Bucci L, Capri M, et al. Immunosenescence and immunogenetics of human longevity. Neuroimmunomodulation. 2008;15(4–6):224–240. doi:10.1159/000156466
  • Mittelbrunn M, Kroemer G. Hallmarks of T cell aging. Nat Immunol. 2021;22(6):687–698. doi:10.1038/s41590-021-00927-z
  • Pang WW, Price EA, Sahoo D, et al. Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. Proc Natl Acad Sci USA. 2011;108(50):20012–20017. doi:10.1073/pnas.1116110108
  • Quinn KM, Fox A, Harland KL, et al. Age-related decline in primary CD8(+) T cell responses is associated with the development of senescence in virtual memory CD8(+) T cells. Cell Rep. 2018;23(12):3512–3524. doi:10.1016/j.celrep.2018.05.057
  • Han S, Yang K, Ozen Z, et al. Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice. J Immunol. 2003;170(3):1267–1273. doi:10.4049/jimmunol.170.3.1267
  • Camous X, Pera A, Solana R, Larbi A. NK cells in healthy aging and age-associated diseases. J Biomed Biotechnol. 2012;2012:195956. doi:10.1155/2012/195956
  • Stout RD, Suttles J. Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changes. Immunol Rev. 2005;205:60–71. doi:10.1111/j.0105-2896.2005.00260.x
  • Uyemura K, Castle SC, Makinodan T. The frail elderly: role of dendritic cells in the susceptibility of infection. Mech Ageing Dev. 2002;123(8):955–962. doi:10.1016/s0047-6374(02)00033-7
  • Li X, Marmar T, Xu Q, et al. Predictive indicators of severe COVID-19 independent of comorbidities and advanced age: a nested case-control study. Epidemiol Infect. 2020;148:e255. doi:10.1017/s0950268820002502
  • Zhou Z, Zhang M, Wang Y, et al. Clinical characteristics of older and younger patients infected with SARS-CoV-2. Aging. 2020;12(12):11296–11305. doi:10.18632/aging.103535
  • Chen Q, Wang L, Yu W, et al. Recommendations for the prevention and treatment of the novel coronavirus pneumonia in the elderly in China. Aging Med. 2020;3(2):66–73. doi:10.1002/agm2.12113
  • Ciabattini A, Nardini C, Santoro F, Garagnani P, Franceschi C, Medaglini D. Vaccination in the elderly: the challenge of immune changes with aging. Semin Immunol. 2018;40:83–94. doi:10.1016/j.smim.2018.10.010
  • Collier DA, Ferreira I, Kotagiri P, et al. Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2. Nature. 2021;596(7872):417–422. doi:10.1038/s41586-021-03739-1
  • Li J, Hui A, Zhang X, et al. Safety and immunogenicity of the SARS-CoV-2 BNT162b1 mRNA vaccine in younger and older Chinese adults: a randomized, placebo-controlled, double-blind Phase 1 study. Nat Med. 2021;27(6):1062–1070. doi:10.1038/s41591-021-01330-9
  • Dent E, Martin FC, Bergman H, Woo J, Romero-Ortuno R, Walston JD. Management of frailty: opportunities, challenges, and future directions. Lancet. 2019;394(10206):1376–1386. doi:10.1016/s0140-6736(19)31785-4
  • Hoogendijk EO, Suanet B, Dent E, Deeg DJ, Aartsen MJ. Adverse effects of frailty on social functioning in older adults: results from the Longitudinal Aging Study Amsterdam. Maturitas. 2016;83:45–50. doi:10.1016/j.maturitas.2015.09.002
  • Hanlon P, Nicholl BI, Jani BD, Lee D, McQueenie R, Mair FS. Frailty and pre-frailty in middle-aged and older adults and its association with multimorbidity and mortality: a prospective analysis of 493 737 UK Biobank participants. Lancet Public Health. 2018;3(7):e323–e332. doi:10.1016/s2468-2667(18)30091-4
  • Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol a Biol Sci Med Sci. 2001;56(3):M146–56. doi:10.1093/gerona/56.3.m146
  • Walston J, Robinson TN, Zieman S, et al. Integrating frailty research into the medical specialties-report from a U13 conference. J Am Geriatr Soc. 2017;65(10):2134–2139. doi:10.1111/jgs.14902
  • Vetrano DL, Triolo F, Maggi S, et al. Fostering healthy aging: the interdependency of infections, immunity and frailty. Ageing Res Rev. 2021;69:101351. doi:10.1016/j.arr.2021.101351
  • Kundi H, Wadhera RK, Strom JB, et al. Association of frailty with 30-day outcomes for acute myocardial infarction, heart failure, and pneumonia among elderly adults. JAMA Cardiol. 2019;4(11):1084–1091. doi:10.1001/jamacardio.2019.3511
  • Prendki V, Tiseo G, Falcone M. Caring for older adults during the COVID-19 pandemic. Clin Microbiol Infect. 2022;28:785–791. doi:10.1016/j.cmi.2022.02.040
  • Hewitt J, Carter B, Vilches-Moraga A, et al. The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study. Lancet Public Health. 2020;5(8):e444–e451. doi:10.1016/s2468-2667(20)30146-8
  • Pranata R, Henrina J, Lim MA, et al. Clinical frailty scale and mortality in COVID-19: a systematic review and dose-response meta-analysis. Arch Gerontol Geriatr. 2021;93:104324. doi:10.1016/j.archger.2020.104324
  • Roschel H, Artioli GG, Gualano B. Risk of increased physical inactivity during COVID-19 outbreak in older people: a call for actions. J Am Geriatr Soc. 2020;68(6):1126–1128. doi:10.1111/jgs.16550
  • Murukesu RR, Singh DKA, Shahar S, Subramaniam P. Physical activity patterns, psychosocial well-being and coping strategies among older persons with cognitive frailty of the ”WE-RISE” trial throughout the COVID-19 movement control order. Clin Interv Aging. 2021;16:415–429. doi:10.2147/cia.S290851
  • Breen L, Stokes KA, Churchward-Venne TA, et al. Two weeks of reduced activity decreases leg lean mass and induces ”anabolic resistance” of myofibrillar protein synthesis in healthy elderly. J Clin Endocrinol Metab. 2013;98(6):2604–2612. doi:10.1210/jc.2013-1502
  • Reidy PT, McKenzie AI, Mahmassani Z, et al. Skeletal muscle ceramides and relationship with insulin sensitivity after 2 weeks of simulated sedentary behaviour and recovery in healthy older adults. J Physiol. 2018;596(21):5217–5236. doi:10.1113/jp276798
  • Wall BT, Dirks ML, van Loon LJ. Skeletal muscle atrophy during short-term disuse: implications for age-related sarcopenia. Ageing Res Rev. 2013;12(4):898–906. doi:10.1016/j.arr.2013.07.003
  • Hartley P, Costello P, Fenner R, et al. Change in skeletal muscle associated with unplanned hospital admissions in adult patients: a systematic review and meta-analysis. PLoS One. 2019;14(1):e0210186. doi:10.1371/journal.pone.0210186
  • Kelaiditi E, Cesari M, Canevelli M, et al. Cognitive frailty: rational and definition from an (I.A.N.A./I.A.G.G.) international consensus group. J Nutr Health Aging. 2013;17(9):726–734. doi:10.1007/s12603-013-0367-2
  • Boccardi M, Boccardi V. Silent cognitive frailty at the interplay between delirium and COVID-19. Asian J Psychiatr. 2021;57:102565. doi:10.1016/j.ajp.2021.102565
  • Franceschi C, Capri M, Monti D, et al. Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans. Mech Ageing Dev. 2007;128(1):92–105. doi:10.1016/j.mad.2006.11.016
  • Baum A, Kaboli PJ, Schwartz MD. Reduced In-person and increased telehealth outpatient visits during the COVID-19 pandemic. Ann Intern Med. 2021;174(1):129–131. doi:10.7326/m20-3026
  • Roy J, Jain R, Golamari R, Vunnam R, Sahu N. COVID-19 in the geriatric population. Int J Geriatr Psychiatry. 2020;35(12):1437–1441. doi:10.1002/gps.5389
  • Kramer BJ, Cleary JF, Mahoney JE. Enhancing palliative care for low-income elders with chronic disease: feasibility of a hospice consultation model. J Soc Work End Life Palliat Care. 2014;10(4):356–377. doi:10.1080/15524256.2014.975088
  • Syed ST, Sharp LK, Kim Y, et al. Relationship between medication adherence and distance to dispensing pharmacies and prescribers among an urban Medicaid population with diabetes mellitus. Pharmacotherapy. 2016;36(6):590–597. doi:10.1002/phar.1757
  • Chan EYY, Kim JH, Lo ESK, et al. What happened to people with non-communicable diseases during COVID-19: implications of H-EDRM policies. Int J Environ Res Public Health. 2020;17(15):5588. doi:10.3390/ijerph17155588
  • Wright A, Salazar A, Mirica M, Volk LA, Schiff GD. The invisible epidemic: neglected chronic disease management during COVID-19. J Gen Intern Med. 2020;35(9):2816–2817. doi:10.1007/s11606-020-06025-4
  • Hartmann-Boyce J, Morris E, Goyder C, et al. Diabetes and COVID-19: risks, management, and learnings from other national disasters. Diabetes Care. 2020;43(8):1695–1703. doi:10.2337/dc20-1192
  • Palmer K, Monaco A, Kivipelto M, et al. The potential long-term impact of the COVID-19 outbreak on patients with non-communicable diseases in Europe: consequences for healthy ageing. Aging Clin Exp Res. 2020;32(7):1189–1194. doi:10.1007/s40520-020-01601-4
  • Singh K, Kondal D, Mohan S, et al. Health, psychosocial, and economic impacts of the COVID-19 pandemic on people with chronic conditions in India: a mixed methods study. BMC Public Health. 2021;21(1):685. doi:10.1186/s12889-021-10708-w
  • Kretchy IA, Asiedu-Danso M, Kretchy JP. Medication management and adherence during the COVID-19 pandemic: perspectives and experiences from low-and middle-income countries. Res Social Adm Pharm. 2021;17(1):2023–2026. doi:10.1016/j.sapharm.2020.04.007
  • Karter AJ, Parker MM, Moffet HH, et al. Missed appointments and poor glycemic control: an opportunity to identify high-risk diabetic patients. Med Care. 2004;42(2):110–115. doi:10.1097/01.mlr.0000109023.64650.73
  • Schectman JM, Schorling JB, Voss JD. Appointment adherence and disparities in outcomes among patients with diabetes. J Gen Intern Med. 2008;23(10):1685–1687. doi:10.1007/s11606-008-0747-1
  • Syed ST, Gerber BS, Sharp LK. Traveling towards disease: transportation barriers to health care access. J Community Health. 2013;38(5):976–993. doi:10.1007/s10900-013-9681-1
  • Gruss J, Smith CH. Demonstrating the vital role of physiatry throughout the health care continuum: lessons learned from the impacts of the COVID-19 pandemic on skilled nursing facilities. Pm r. 2021;13(6):563–571. doi:10.1002/pmrj.12609
  • Nguyen HL, Tran OT, Ha DA, et al. Impact of the COVID-19 pandemic on clinical research activities: survey of study participants and health care workers participating in a hypertension trial in Vietnam. PLoS One. 2021;16(7):e0253664. doi:10.1371/journal.pone.0253664
  • Machado CLF, Pinto RS, Brusco CM, Cadore EL, Radaelli R. COVID-19 pandemic is an urgent time for older people to practice resistance exercise at home. Exp Gerontol. 2020;141:111101. doi:10.1016/j.exger.2020.111101
  • Jensen GL, McGee M, Binkley J. Nutrition in the elderly. Gastroenterol Clin North Am. 2001;30(2):313–334. doi:10.1016/s0889-8553(05)70184-9
  • Kalousova L. Social isolation as a risk factor for inadequate diet of older Eastern Europeans. Int J Public Health. 2014;59(5):707–714. doi:10.1007/s00038-014-0582-6
  • Boulos C, Salameh P, Barberger-Gateau P. Social isolation and risk for malnutrition among older people. Geriatr Gerontol Int. 2017;17(2):286–294. doi:10.1111/ggi.12711
  • Delerue Matos A, Barbosa F, Cunha C, Voss G, Correia F. Social isolation, physical inactivity and inadequate diet among European middle-aged and older adults. BMC Public Health. 2021;21(1):924. doi:10.1186/s12889-021-10956-w
  • Ammar A, Brach M, Trabelsi K, et al. Effects of COVID-19 home confinement on eating behaviour and physical activity: results of the ECLB-COVID19 international online survey. Nutrients. 2020;12(6):1583. doi:10.3390/nu12061583
  • Palaniswamy S, Hyppönen E, Williams DM, et al. Potential determinants of vitamin D in Finnish adults: a cross-sectional study from the Northern Finland birth cohort 1966. BMJ Open. 2017;7(3):e013161. doi:10.1136/bmjopen-2016-013161
  • Wei J, Zhu A, Ji JS, Comparison A. Study of Vitamin D deficiency among older adults in China and the United States. Sci Rep. 2019;9(1):19713. doi:10.1038/s41598-019-56297-y
  • Sutton E, Catling J, Segaert K, Veldhuijzen van Zanten J. cognitive health worries, reduced physical activity and fewer social interactions negatively impact psychological wellbeing in older adults during the COVID-19 pandemic. Front Psychol. 2022;13:823089. doi:10.3389/fpsyg.2022.823089
  • Schmidt AL, Labaki C, Hsu CY, et al. COVID-19 vaccination and breakthrough infections in patients with cancer. Ann Oncol. 2022;33(3):340–346. doi:10.1016/j.annonc.2021.12.006
  • Reed PG, Boyd M, Buckwalter KC. Mental health of older adults. West J Nurs Res. 1989;11(2):143–163. doi:10.1177/019394598901100202
  • Grolli RE, Mingoti MED, Bertollo AG, et al. Impact of COVID-19 in the mental health in elderly: psychological and biological updates. Mol Neurobiol. 2021;58(5):1905–1916. doi:10.1007/s12035-020-02249-x
  • Xiang YT, Yang Y, Li W, et al. Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed. Lancet Psychiatry. 2020;7(3):228–229. doi:10.1016/s2215-0366(20)30046-8
  • Wang C, Tee M, Roy AE, et al. The impact of COVID-19 pandemic on physical and mental health of Asians: a study of seven middle-income countries in Asia. PLoS One. 2021;16(2):e0246824. doi:10.1371/journal.pone.0246824
  • Yang XY, Peng S, Yang T, Cottrell RR. Changing trends of mental and behavioral responses and associations during the COVID-19 epidemic in China: a panel study. Health Educ Res. 2021;36(2):151–158. doi:10.1093/her/cyab012
  • Yao H, Chen JH, Xu YF. Patients with mental health disorders in the COVID-19 epidemic. Lancet Psychiatry. 2020;7(4):e21. doi:10.1016/s2215-0366(20)30090-0
  • Russell G, Lightman S. The human stress response. Nat Rev Endocrinol. 2019;15(9):525–534. doi:10.1038/s41574-019-0228-0
  • Friedler B, Crapser J, McCullough L. One is the deadliest number: the detrimental effects of social isolation on cerebrovascular diseases and cognition. Acta Neuropathol. 2015;129(4):493–509. doi:10.1007/s00401-014-1377-9
  • Parisi V, Leosco D. Precision medicine in COVID-19: IL-1β a potential target. JACC Basic Transl Sci. 2020;5(5):543–544. doi:10.1016/j.jacbts.2020.04.006
  • Yan C, Luo Z, Li W, et al. Disturbed Yin-Yang balance: stress increases the susceptibility to primary and recurrent infections of herpes simplex virus type 1. Acta Pharm Sin B. 2020;10(3):383–398. doi:10.1016/j.apsb.2019.06.005
  • Ismail H, Marshall VD, Patel M, Tariq M, Mohammad RA. The impact of the COVID-19 pandemic on medical conditions and medication adherence in people with chronic diseases. J Am Pharm Assoc. 2021. doi:10.1016/j.japh.2021.11.013
  • de Lusignan S, Correa A, Smith GE, et al. RCGP research and surveillance centre: 50 years’ surveillance of influenza, infections, and respiratory conditions. Br J Gen Pract. 2017;67(663):440–441. doi:10.3399/bjgp17X692645
  • Tran BX, Phan HT, Nguyen TPT, et al. Reaching further by Village Health Collaborators: the informal health taskforce of Vietnam for COVID-19 responses. J Glob Health. 2020;10(1):010354. doi:10.7189/jogh.10.010354
  • Le HT, Mai HT, Pham HQ, et al. Feasibility of intersectoral collaboration in epidemic preparedness and response at grassroots levels in the threat of COVID-19 pandemic in Vietnam. Front Public Health. 2020;8:589437. doi:10.3389/fpubh.2020.589437
  • Akbar MA, Juniarti N, Yamin A. The roles of community health nurses’ in covid-19 management in Indonesia: a qualitative study. Int J Community Based Nurs Midwifery. 2022;10(2):96–109. doi:10.30476/ijcbnm.2021.90884.1739
  • Steinman MA, Perry L, Perissinotto CM. Meeting the care needs of older adults isolated at home during the COVID-19 pandemic. JAMA Intern Med. 2020;180(6):819–820. doi:10.1001/jamainternmed.2020.1661
  • Mistry SK, Ali A, Akther F, Yadav UN, Harris MF. Exploring fear of COVID-19 and its correlates among older adults in Bangladesh. Global Health. 2021;17(1):47. doi:10.1186/s12992-021-00698-0
  • Gummidi B, John O, Jha V. Continuum of care for non-communicable diseases during COVID-19 pandemic in rural India: a mixed methods study. J Family Med Prim Care. 2020;9(12):6012–6017. doi:10.4103/jfmpc.jfmpc_1805_20
  • Yadav UN, Mistry SK, Ghimire S, et al. Recognizing the roles of primary health care in addressing non-communicable diseases in low- and middle-income countries: lesson from COVID-19, implications for the future. J Glob Health. 2021;11:03120. doi:10.7189/jogh.11.03120
  • Ruíz-Fernández MD, Fernández-Medina IM, Gálvez Ramírez F, Granero-Molina J, Fernández-Sola C, Hernández-Padilla JM. Experiences of home care nurses during the COVID-19 pandemic. Nurs Res. 2022;71(2):111–118. doi:10.1097/nnr.0000000000000566
  • García JMM, Izquierdo JA, Pérez MIG. [COVID-19 in Spain, how did we get here?] COVID-19 en España, ¿cómo hemos llegado hasta aquí? Aten Primaria. 2020;52(10):676–679. Spanish. doi:10.1016/j.aprim.2020.10.003
  • Visser M, Schaap LA, Wijnhoven HAH. Self-reported impact of the COVID-19 pandemic on nutrition and physical activity behaviour in Dutch older adults living independently. Nutrients. 2020;12(12):3708. doi:10.3390/nu12123708
  • Berg-Weger M, Morley JE. Editorial: loneliness and social isolation in older adults during the COVID-19 pandemic: implications for gerontological social work. J Nutr Health Aging. 2020;24(5):456–458. doi:10.1007/s12603-020-1366-8
  • Zheng SQ, Yang L, Zhou PX, Li HB, Liu F, Zhao RS. Recommendations and guidance for providing pharmaceutical care services during COVID-19 pandemic: a China perspective. Res Social Adm Pharm. 2021;17(1):1819–1824. doi:10.1016/j.sapharm.2020.03.012
  • Aruru M, Truong HA, Clark S. Pharmacy Emergency Preparedness and Response (PEPR): a proposed framework for expanding pharmacy professionals’ roles and contributions to emergency preparedness and response during the COVID-19 pandemic and beyond. Res Social Adm Pharm. 2021;17(1):1967–1977. doi:10.1016/j.sapharm.2020.04.002
  • Visacri MB, Figueiredo IV, Lima TM. Role of pharmacist during the COVID-19 pandemic: a scoping review. Res Social Adm Pharm. 2021;17(1):1799–1806. doi:10.1016/j.sapharm.2020.07.003
  • Kambayashi D, Manabe T, Kawade Y, Hirohara M. Knowledge, attitudes, and practices regarding COVID-19 among pharmacists partnering with community residents: a national survey in Japan. PLoS One. 2021;16(10):e0258805. doi:10.1371/journal.pone.0258805
  • Thiruchselvam T, Naglie G, Moineddin R, et al. Risk factors for medication nonadherence in older adults with cognitive impairment who live alone. Int J Geriatr Psychiatry. 2012;27(12):1275–1282. doi:10.1002/gps.3778
  • Gellad WF, Grenard JL, Marcum ZA. A systematic review of barriers to medication adherence in the elderly: looking beyond cost and regimen complexity. Am J Geriatr Pharmacother. 2011;9(1):11–23. doi:10.1016/j.amjopharm.2011.02.004
  • Westra BL, Paitich N, Ekstrom D, et al. Getting on with living life: experiences of older adults after home care. Home Healthc Nurse. 2013;31(9):493–501. doi:10.1097/NHH.0b013e3182a87654
  • Osakwe ZT. Home care and use of telehealth amidst the COVID-19 pandemic. Home Healthc Now. 2020;38(4):229–230. doi:10.1097/nhh.0000000000000900
  • Hickey S, Gomez J, Meller B, et al. Interactive home telehealth and burns: a pilot study. Burns. 2017;43(6):1318–1321. doi:10.1016/j.burns.2016.11.013
  • Hirko KA, Kerver JM, Ford S, et al. Telehealth in response to the COVID-19 pandemic: implications for rural health disparities. J Am Med Inform Assoc. 2020;27(11):1816–1818. doi:10.1093/jamia/ocaa156
  • Barlow J, Wright C, Sheasby J, Turner A, Hainsworth J. Self-management approaches for people with chronic conditions: a review. Patient Educ Couns. 2002;48(2):177–187. doi:10.1016/s0738-3991(02)00032-0
  • Guo Y, Albright D. The effectiveness of telehealth on self-management for older adults with a chronic condition: a comprehensive narrative review of the literature. J Telemed Telecare. 2018;24(6):392–403. doi:10.1177/1357633x17706285
  • Jerant AF, von Friederichs-Fitzwater MM, Moore M. Patients’ perceived barriers to active self-management of chronic conditions. Patient Educ Couns. 2005;57(3):300–307. doi:10.1016/j.pec.2004.08.004
  • Doraiswamy S, Abraham A, Mamtani R, Cheema S. Use of telehealth during the COVID-19 Pandemic: scoping review. J Med Internet Res. 2020;22(12):e24087. doi:10.2196/24087
  • Hudson GM, Sprow K. Promoting physical activity during the COVID-19 pandemic: implications for obesity and chronic disease management. J Phys Act Health. 2020;17(7):685–687. doi:10.1123/jpah.2020-0318
  • Jiménez-Pavón D, Carbonell-Baeza A, Lavie CJ. Physical exercise as therapy to fight against the mental and physical consequences of COVID-19 quarantine: special focus in older people. Prog Cardiovasc Dis. 2020;63(3):386–388. doi:10.1016/j.pcad.2020.03.009
  • Laddu DR, Lavie CJ, Phillips SA, Arena R. Physical activity for immunity protection: inoculating populations with healthy living medicine in preparation for the next pandemic. Prog Cardiovasc Dis. 2021;64:102–104. doi:10.1016/j.pcad.2020.04.006
  • Cadore EL, Sáez de Asteasu ML, Izquierdo M. Multicomponent exercise and the hallmarks of frailty: considerations on cognitive impairment and acute hospitalization. Exp Gerontol. 2019;122:10–14. doi:10.1016/j.exger.2019.04.007
  • Martínez-Velilla N, Casas-Herrero A, Zambom-Ferraresi F, et al. Effect of exercise intervention on functional decline in very elderly patients during acute hospitalization: a randomized clinical trial. JAMA Intern Med. 2019;179(1):28–36. doi:10.1001/jamainternmed.2018.4869
  • Tu J, Wang C, Wu S. The internet hospital: an emerging innovation in China. Lancet Glob Health. 2015;3(8):e445–e446. doi:10.1016/s2214-109x(15)00042-x
  • Ding L, She Q, Chen F, et al. The internet hospital plus drug delivery platform for health management during the COVID-19 pandemic: observational study. J Med Internet Res. 2020;22(8):e19678. doi:10.2196/19678
  • Gong K, Xu Z, Cai Z, Chen Y, Wang Z. Internet hospitals help prevent and control the epidemic of COVID-19 in China: multicenter user profiling study. J Med Internet Res. 2020;22(4):e18908. doi:10.2196/18908
  • Cleland C, Ferguson S, Ellis G, Hunter RF. Validity of the International Physical Activity Questionnaire (IPAQ) for assessing moderate-to-vigorous physical activity and sedentary behaviour of older adults in the United Kingdom. BMC Med Res Methodol. 2018;18(1):176. doi:10.1186/s12874-018-0642-3
  • Radbruch L, Sabatowski R, Elsner F, Everts J, Mendoza T, Cleeland C. Validation of the German version of the brief fatigue inventory. J Pain Symptom Manage. 2003;25(5):449–458. doi:10.1016/s0885-3924(03)00073-3
  • Spitzer RL, Kroenke K, Williams JB. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary care evaluation of mental disorders. Patient health questionnaire. JAMA. 1999;282(18):1737–1744. doi:10.1001/jama.282.18.1737
  • Spitzer RL, Kroenke K, Williams JB, Löwe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006;166(10):1092–1097. doi:10.1001/archinte.166.10.1092
  • Gago CM, Lopez-Cepero A, O’Neill J, et al. Association of a single-item self-rated diet construct with diet quality measured with the alternate healthy eating index. Front Nutr. 2021;8:646694. doi:10.3389/fnut.2021.646694
  • Folstein MF, Folstein SE, McHugh PR. ”Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189–198. doi:10.1016/0022-3956(75)90026-6
  • Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193–213. doi:10.1016/0165-1781(89)90047-4