90
Views
8
CrossRef citations to date
0
Altmetric
Review

The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection

, , , , , & show all
Pages 149-156 | Published online: 11 Feb 2013

References

  • WebbRAWho, what, where and when – influences on cutaneous vitamin D synthesisProg Biophys Mol Biol200692172516766240
  • DussoASBrownAJSlatopolskyEVitamin DAm J Physiol Renal Physiol2005289828
  • GrantWBHolickMFBenefits and requirements of vitamin D for optimal health: A reviewAltern Med Rev2005109411115989379
  • LappeJMTravers-GustafsonDDaviesKMVitamin D and calcium supplementation reduces cancer risk: results of a randomized trialAm J Clin Nutr2007851586159117556697
  • Gouni-BertholdIKroneWBertholdHKVitamin D and cardiovascular diseaseCurr Vasc Pharmacol2009741442219601865
  • ParkerJHashmiODuttonDLevels of vitamin D and cardiometabolic disorders: systematic review and meta-analysisMaturitas20106522523620031348
  • ScraggRSowersMBellCSerum 25-hydroxyvitamin D, ethnicity, and blood pressure in the Third National Health and Nutrition Examination SurveyAm J Hypertens20072071371917586404
  • FreedmanBIWagenknechtLEHairstonKGVitamin D, adiposity, and calcified atherosclerotic plaque in African-AmericansJ Clin Endocrinol Metab2010951076108320061416
  • DeLucaHFOverview of general physiologic features and functions of vitamin DAm J Clin Nutr200480Suppl 6S1689S1696
  • MitsuhashiTMorrisRCJrIvesHE1,25-dihydroxyvitamin D3 modulates growth of vascular smooth muscle cellsJ Clin Invest199187188918951645744
  • MichosEDMelamedMLVitamin D and cardiovascular disease riskCurr Opin Clin Nutr Metab Care20081171218090651
  • PanichiVDe PietroSAndreiniBCalcitriol modulates in vivo and in vitro cytokine production: a role for intracellular calciumKidney Int199854146314699844122
  • BellowsCGReimersSMHeerscheJNExpression of mRNAs for type-I collagen, bone sialoprotein, osteocalcin, and osteopontin at different stages of osteoblastic differentiation and their regulation by 1,25 dihydroxyvitamin D3Cell Tissue Res199929724925910470495
  • DrissiHPouliotAKoolloosC1,25-(OH)2-vitamin D3 suppresses the bone-related Runx2/Cbfa1 gene promoterExp Cell Res200227432333311900492
  • AiharaKAzumaHAkaikeMDisruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in miceJ Biol Chem2004279357983580215205460
  • SimpsonRUHersheySHNibbelinkKACharacterization of heart size and blood pressure in the vitamin D receptor knockout mouseJ Steroid Biochem Mol Biol200710352152417275289
  • MeemsLMvan der HarstPvan GilstWHde BoerRAVitamin D biology in heart failure: molecular mechanisms and systematic reviewCurr Drug Targets201112294120795939
  • TalmorYGolanEBenchetritSCalcitriol blunts the deleterious impact of advanced glycation end products on endothelial cellsAm J Physiol Renal Physiol200829410591064
  • HsiaJHeissGRenHCalcium/vitamin D supplementation and cardiovascular eventsCirculation200711584685417309935
  • ZittermannAFrischSBertholdHKVitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markersAm J Clin Nutr2009891321132719321573
  • ElaminMBAbu ElnourNOElaminKBVitamin D and cardiovascular outcomes: a systematic review and meta-analysisJ Clin Endocrinol Metab2011961931194221677037
  • AutierPGandiniSVitamin D supplementation and total mortality: a meta-analysis of randomized controlled trialsArch Intern Med2007167161730173717846391
  • DobnigHPilzSScharnaglHRennerWIndependent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortalityArch Intern Med20081681340134918574092
  • InagumaDNagayaHHaraKRelationship between serum 1,25-dihydroxyvitamin D and mortality in patients with pre-dialysis chronic kidney diseaseClin Exp Nephrol20081212613118180871
  • BakerLRAbramsLRoeCJ1,25(OH)2D3 administration in moderate renal failure: a prospective double-blind trialKidney Int1989356616692651758
  • MoeSMDrüekeTBBlockGAKDIGO clinical practice guidelines for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD)Kidney Int Suppl2009113S1S13019644521
  • MoeSDrüekeTCunninghamJDefinition, evaluation, and classification of renal osteodystrophy: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO)Kidney Int2006691945195316641930
  • WatsonKEAbrolatMLMaloneLLActive serum vitamin D levels are inversely correlated with coronary calcificationCirculation199796175517609323058
  • TengMWolfMOfsthunMNActivated injectable vitamin D and hemodialysis survival: a historical cohort studyJ Am Soc Nephrol2005161115112515728786
  • BianchiMLColantonioGCampaniniFCalcitriol and calcium carbonate therapy in early chronic renal failureNephrol Dial Transplant19949159515997870349
  • YildizAMemisogluEOflazHAtherosclerosis and vascular calcification are independent predictors of left ventricular hypertrophy in chronic haemodialysis patientsNephrol Dial Transplant20052076076715716296
  • LondonGMCardiovascular calcifications in uremic patients: clinical impact on cardiovascular functionJ Am Soc Nephrol20039Suppl 4S305S30912939386
  • FoleyRNParfreyPSSarnakMJClinical epidemiology of cardiovascular disease in chronic renal diseaseAm J Kidney Dis199832S112S1199820470
  • [No authors listed]VI. Causes of death in ESRDAm J Kidney Dis1999342 Suppl 1S87S9410431005
  • [No authors listed]V. Patient mortality and survival in ESRDAm J Kidney Dis1999342 Suppl 1S748610431004
  • GoodmanWGCoburnJWThe use of 1,25-dihydroxyvitamin D3 in early renal failureAnnu Rev Med1992432272371580587
  • DemerLLTintutYVascular calcification: pathobiology of multifaceted diseaseCirculation20081172938294818519861
  • BasALopezIPerezJRodriguezMAguilera-TejeroEReversibility of calcitriol-induced medial artery calcification in rats with intact renal functionJ Bone Miner Res20062148449016491297
  • StubbsJRLiuSTangWRole of hyperphosphatemia and 1,25- dihydroxyvitamin D in vascular calcification and mortality in fibroblastic growth factor 23 null miceJ Am Soc Nephrol2007182116212417554146
  • CozzolinoMBrancaccioDGallieniMSlatopolskyEPathogenesis of vascular calcification in chronic kidney diseaseKidney Int20056842943616014020
  • BrownAJFinchJTakahashiFSlatopolskyECalcemic activity of 19-Nor-1,25(OH)(2)D(2) decreases with duration of treatmentJ Am Soc Nephrol2000112088209411053485
  • MizobuchiMOgataHKoiwaFKinugasaEAkizawaTVitamin D and vascular calcification in chronic kidney diseaseBone200945Suppl 1S26S2919442619
  • AndressDNonclassical aspects of differential vitamin D receptor activation: implications for survival in patients with chronic kidney diseaseDrugs2007671999201217883284
  • ChengJZhangWZhangXLiXChenJEfficacy and safety of paricalcitol therapy for chronic kidney disease: a meta-analysisClin J Am Soc Nephrol2012739140022223607
  • SpragueSMLlachFAmdahlMTaccettaCBatlleDParicalcitol versus calcitriol in the treatment of secondary hyperparathyroidismKidney Int2003631483149012631365
  • BrownJAFinchJSlatopolskyEDifferential effects of 19-nor-1,25-dihydroxyvitamin D2 and 1,25-dihydroxyvitamin D3 on intestinal calcium and phosphate transportJ Lab Clin Med200213927928412032488
  • NakaneMMaJRoseAEDifferential effects of vitamin D analogs on calcium transportJ Steroid Biochem Mol Biol2007103848917046242
  • SpragueSMLermaEMcCormmickDSuppression of parathyroid hormone secretion in hemodialysis patients: comparison of paricalcitol with calcitriolAm J Kidney Dis200138S51S5611689388
  • TakahashiFFinchJLDendaMDussoASBrownAJSlatopolskyEA new analog of 1,25-(OH)2D3, 19-NOR-1,25-(OH)2D2, suppresses serum PTH and parathyroid gland growth in uremic rats without elevation of intestinal vitamin D receptor contentAm J Kidney Dis1997301051129214408
  • RodriguezMMartinez-MorenoJMRodríguez-OrtizMEMuñoz-CastañedaJRAlmadenYVitamin D and vascular calcification in chronic kidney diseaseKidney Blood Press Res20113426126821691129
  • LiXSpeerMYYangHBergenJGiachelliCMVitamin D receptor activators induce an anticalcific paracrine program in macrophages: requirement of osteopontinArterioscler Thromb Vasc Biol20103032132619948844
  • Sanchez-NiñoMDBozicMCórdoba-LanúsEBeyond proteinuria: VDR activation reduces renal inflammation in experimental diabetic nephropathyAm J Physiol Renal Physiol2012302647657
  • ResnickLMMüllerFBLaraghJHCalcium-regulating hormones in essential hypertension. Relation to plasma renin activity and sodium metabolismAnn Intern Med19861056496543532893
  • FreundlichMQuirozYZhangZSuppression of renin-angiotensin gene expression in the kidney by paricalcitolKidney Int2008741394140218813285
  • ParkJWBaeEHKimIJRenoprotective effects of paricalcitol on gentamicin-induced kidney injury in ratsAm J Physiol Renal Physiol2010298301313
  • SochorováKBudinskýVRozkováDParicalcitol (19-nor-1, 25-dihydroxyvitamin D2) and calcitriol (1,25-dihydroxyvitamin D3) exert potent immunomodulatory effects on dendritic cells and inhibit induction of antigen-specific T cellsClin Immunol2009133697719660988
  • AriEKedrahAEAlahdabYAntioxidant and renoprotective effects of paricalcitol on experimental contrast-induced nephropathy modelBr J Radiol2012851038104322815410
  • MeemsLMCannonMVMahmudHThe vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overloadJ Steroid Biochem Mol Biol201213228228922800987
  • HusainKFerderLMizobuchiMFinchJSlatopolskyECombination therapy with paricalcitol and enalapril ameliorates cardiac oxidative injury in uremic ratsAm J Nephrol20092946547219033720
  • ParkJWChoJWJooSYParicalcitol prevents cisplatin-induced renal injury by suppressing apoptosis and proliferationEur J Pharmacol201268330130922449373
  • MizobuchiMMorrisseyJFinchJLCombination therapy with an angiotensin-converting enzyme inhibitor and a vitamin D analog suppresses the progression of renal insufficiency in uremic ratsJ Am Soc Nephrol2007181796180617513326
  • HusainKSuarezEIsidroAFerderLEffects of paricalcitol and enalapril on atherosclerotic injury in mouse aortasAm J Nephrol20103229630420720404
  • KongJKimGHWeiMTherapeutic effects of vitamin D analogs on cardiac hypertrophy in spontaneously hypertensive ratsAm J Pathol201017762263120616348
  • MizobuchiMNakamuraHTokumotoMMyocardial effects of VDR activators in renal failureJ Steroid Biochem Mol Biol201012118819220236614
  • FragaCBlancoMVigoEAutogenesis of the vitamin D receptor in the rat heartHistochem Cell Biol200211754755012107506
  • Wu-WongJRNoonanWNakaneMVitamin d receptor activation mitigates the impact of uremia on endothelial function in the 5/6 nephrectomized ratsInt J Endocrinol Epub February 10, 2010
  • MizobuchiMFinchJLMartinDRSlatopolskyEDifferential effects of vitamin D receptor activators on vascular calcification in uremic ratsKidney Int20077270971517597697
  • CardúsAPanizoSParisiEFernandezEValdivielsoJMDifferential effects of vitamin D analogs on vascular calcificationJ Bone Miner Res20072286086617352647
  • TengMWolfMLowrieEOfsthunNLazarusJMThadhaniRSurvival of patients undergoing hemodialysis with paricalcitol or calcitriol therapyEngl J Med312003349446456
  • TentoriFHuntWCStidleyCAMortality risk among hemodialysis patients receiving different vitamin D analogsKidney Int2006701858186517021609
  • CozzolinoMBrancaccioDCannellaGVDRA therapy is associated with improved survival in dialysis patients with serum intact PTH < = 150 pg/mL: results of the Italian FARO SurveyNephrol Dial Transplant20122793588359422523119
  • HeWKangYSDaiCLiuYBlockade of Wnt/? – catenin signaling by paricalcitol ameliorates proteinuria and kidney injuryJ Am Soc Nephrol2011229010321030600
  • AperisGPaliourasCZervosAArvanitisAAlivanisPThe role of paricalcitol on proteinuriaJ Ren Care201137808421561543
  • AgarwalRAcharyaMTianJAntiproteinuric effect of oral paricalcitol in chronic kidney diseaseKidney Int2005682823282816316359
  • de ZeeuwDAgarwalRAmdahlMSelective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trialLancet20103761543155121055801
  • ThadhaniRAppelbaumEPritchettYVitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trialJAMA201230767468422337679