Comparison of the Effects of Dexmedetomidine and Lidocaine on Stress Response and Postoperative Delirium of Older Patients Undergoing Thoracoscopic Surgery: A Randomized Controlled Trial

References

• Hu CG, Zheng K, Liu GH, et al. Effectiveness and postoperative pain level of single-port versus two-port thoracoscopic lobectomy for lung cancer: a retrospective cohort study. Gen Thorac Cardiovasc Surg. 2021;69(2):318–325. doi:10.1007/s11748-020-01479-z
   PubMed Web of Science ®Google Scholar
• Yun J, Lee J, Shin S, et al. Video-assisted thoracoscopic lobectomy versus open lobectomy in the treatment of large lung cancer: propensity-score matched analysis. J Cardiothorac Surg. 2022;17(1):2. doi:10.1186/s13019-021-01749-8
   PubMed Web of Science ®Google Scholar
• Chen W, Yu Z, Zhang Y, Liu H. Comparison of cost effectiveness between video-assisted thoracoscopic surgery (vats) and open lobectomy: a retrospective study. Cost Eff Resour Alloc. 2021;19(1):55. doi:10.1186/s12962-021-00307-2
   PubMed Web of Science ®Google Scholar
• Huang X, Li L, Feng Q, Wan C. Correlation analysis of inflammatory markers CRP and IL-6 and postoperative delirium (POD) in elderly patients: a meta-analysis of observational studies. J Environ Public Health. 2022;2022:1136386. doi:10.1155/2022/1136386
   PubMed Web of Science ®Google Scholar
• Zhang Y, Jiang Q, Li T. Nalbuphine analgesic and anti-inflammatory effects on patients undergoing thoracoscopic lobectomy during the perioperative period. Exp Ther Med. 2017;14(4):3117–3121. doi:10.3892/etm.2017.4920
   PubMed Web of Science ®Google Scholar
• Jin Z, Hu J, Ma D. Postoperative delirium: perioperative assessment, risk reduction, and management. Br J Anaesth. 2020;125(4):492–504. doi:10.1016/j.bja.2020.06.063
   PubMed Web of Science ®Google Scholar
• Hermanns H, Hollmann MW, Stevens MF, et al. Molecular mechanisms of action of systemic lidocaine in acute and chronic pain: a narrative review. Br J Anaesth. 2019;123(3):335–349. doi:10.1016/j.bja.2019.06.014
   PubMed Web of Science ®Google Scholar
• Lee IW, Schraag S. The use of intravenous lidocaine in perioperative medicine: anaesthetic, analgesic and immune-modulatory aspects. J Clin Med. 2022;11(12):3543. doi:10.3390/jcm11123543
   PubMed Web of Science ®Google Scholar
• Bai YX, Zhang JH, Zhao BC, Liu KX, Bai YW. Dexmedetomidine attenuates one-lung ventilation associated lung injury by suppressing inflammatory responses: a systematic review and meta-analysis. Clin Exp Pharmacol Physiol. 2021;48(9):1203–1214. doi:10.1111/1440-1681.13525
   PubMed Web of Science ®Google Scholar
• Buren MA, Theologis A, Zuraek A, Behrends M, Clark AJ, Leung JM. Lidocaine Infusion for the Management of postoperative Pain and Delirium (LIMPP): protocol for a randomised control trial. BMJ Open. 2022;12(6):e059416. doi:10.1136/bmjopen-2021-059416
   PubMed Web of Science ®Google Scholar
• Liao X, Fu B, Yun J, Lin H, Qian B, Yao Y. Efficacy of systemic lidocaine in postoperative delirium in elderly patients undergoing laparoscopic colorectal surgery: study protocol for a multicentre, prospective, double-blind, randomised, parallel-group, superiority, placebo-controlled trial. BMJ Open. 2022;12(5):e056959. doi:10.1136/bmjopen-2021-056959
   PubMed Web of Science ®Google Scholar
• Duan X, Coburn M, Rossaint R, Sanders RD, Waesberghe JV, Kowark A. Efficacy of perioperative dexmedetomidine on postoperative delirium: systematic review and meta-analysis with trial sequential analysis of randomised controlled trials. Br J Anaesth. 2018;121(2):384–397. doi:10.1016/j.bja.2018.04.046
   PubMed Web of Science ®Google Scholar
• Deiner S, Luo X, Lin HM, et al. Intraoperative infusion of dexmedetomidine for prevention of postoperative delirium and cognitive dysfunction in elderly patients undergoing major elective noncardiac surgery: a randomized clinical trial. JAMA Surg. 2017;152(8):e171505. doi:10.1001/jamasurg.2017.1505
   PubMed Web of Science ®Google Scholar
• Hou YH, Shi WC, Cai S, et al. Effect of intravenous lidocaine on serum interleukin-17 after video-assisted thoracic surgery for non-small-cell lung cancer: a randomized, double-blind, placebo-controlled trial. Drug Des Dev Ther. 2021;15:3379–3390. doi:10.2147/DDDT.S316804
   PubMed Web of Science ®Google Scholar
• Pawlik W, Pawlik J, Kozłowski M, et al. The clinical importance of IL-6, IL-8, and TNF-α in patients with ovarian carcinoma and benign cystic lesions. Diagnostics. 2021;11(9):1625. doi:10.3390/diagnostics11091625
   Web of Science ®Google Scholar
• He L, Qing F, Li M, Lan D. Effects of laparoscopic and traditional open surgery on the levels of IL-6, TNF-α, and Gal-3 in patients with thyroid cancer. Gland Surg. 2021;10(3):1085–1092. doi:10.21037/gs-21-60
   PubMed Web of Science ®Google Scholar
• Wang J, Yin Y, Zhu Y, et al. Thoracic epidural anaesthesia and analgesia ameliorates surgery-induced stress response and postoperative pain in patients undergoing radical oesophagectomy. J Int Med Res. 2019;47(12):6160–6170. doi:10.1177/0300060519866943
   PubMed Web of Science ®Google Scholar
• Ding W, Chen Y, Li D, et al. Investigation of single-dose thoracic paravertebral analgesia for postoperative pain control after thoracoscopic lobectomy – a randomized controlled trial. Int J Surg. 2018;57:8–14. doi:10.1016/j.ijsu.2018.07.006
   PubMed Web of Science ®Google Scholar
• Zhang C, Xie C, Lu Y. Local anesthetic lidocaine and cancer: insight into tumor progression and recurrence. Front Oncol. 2021;11(11):669746. doi:10.3389/fonc.2021.669746
   PubMedGoogle Scholar
• Foo I, Macfarlane AJR, Srivastava D, et al. The use of intravenous lidocaine for postoperative pain and recovery: international consensus statement on efficacy and safety. Anaesthesia. 2021;76(2):238–250. doi:10.1111/anae.15270
   PubMed Web of Science ®Google Scholar
• Dale GJ, Phillips S, Falk GL. The analgesic efficacy of intravenous lidocaine infusion after laparoscopic fundoplication: a prospective, randomised, double-blind, placebo-controlled trial. Local Reg Anesth. 2016;9:87–93. doi:10.2147/LRA.S119483
   PubMedGoogle Scholar
• Weibel S, Jelting Y, Pace NL, et al. Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults. Cochrane Database Syst Rev. 2018;6(6):CD009642. doi:10.1002/14651858.CD009642.pub3
   PubMed Web of Science ®Google Scholar
• Weibel S, Jokinen J, Pace NL, et al. Efficacy and safety of intravenous lidocaine for postoperative analgesia and recovery after surgery: a systematic review with trial sequential analysis. Br J Anaesth. 2016;116(6):770–783. doi:10.1093/bja/aew101
   PubMed Web of Science ®Google Scholar
• Davy A, Fessler J, Fischler M, Le Guen M. Dexmedetomidine and general anesthesia: a narrative literature review of its major indications for use in adults undergoing non-cardiac surgery. Minerva Anestesiol. 2017;83(12):1294–1308. doi:10.23736/S0375-9393.17.12040-7
   PubMed Web of Science ®Google Scholar
• Grape S, Kirkham KR, Frauenknecht J, Albrecht E. Intra-operative analgesia with remifentanil vs. dexmedetomidine: a systematic review and meta-analysis with trial sequential analysis. Anaesthesia. 2019;74(6):793–800. doi:10.1111/anae.14657
   PubMed Web of Science ®Google Scholar
• Su X, Meng ZT, Wu XH, et al. Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial. Lancet. 2016;388(10054):1893–1902. doi:10.1016/S0140-6736(16)30580-3
   PubMed Web of Science ®Google Scholar
• Momeni M, Khalifa C, Lemaire G, et al. Propofol plus low-dose dexmedetomidine infusion and postoperative delirium in older patients undergoing cardiac surgery. Br J Anaesth. 2021;126(3):665–673. doi:10.1016/j.bja.2020.10.041
   PubMed Web of Science ®Google Scholar