References
- BuslKMNogueiraRGYooAJHirschJASchwammLHRostNSPrestroke dementia is associated with poor outcomes after reperfusion therapy among elderly stroke patientsJ Stroke Cerebrovasc Dis Epub12172011
- TanneDTurgemanDAdlerYManagement of acute ischaemic stroke in the elderly: tolerability of thrombolyticsDrugs200161101439145311558833
- Del ZoppoGJSaverJLJauchECAdamsHPJrAmericanHeartAmerican Heart Association Stroke CouncilExpansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association/American Stroke AssociationStroke20094082945294819478221
- LorenzanoSToniDTESPI trial InvestigatorsTESPI (Thrombolysis in Elderly Stroke Patients in Italy): a randomized controlled trial of alteplase (rt-PA) versus standard treatment in acute ischaemic stroke in patients aged more than 80 years where thrombolysis is initiated within three hours after stroke onsetInt J Stroke20127325025722292526
- ToniDLorenzanoSAgnelliGIntravenous thrombolysis with rt-PA in acute ischemic stroke patients aged older than 80 years in ItalyCerebrovasc Dis2008251–212913518073466
- PundikSMcWilliams-DunniganLBlackhamKLOlder age does not increase risk of hemorrhagic complications after intravenous and/or intra-arterial thrombolysis for acute strokeJ Stroke Cerebrovasc Dis200817526627218755405
- SylajaPNCoteRBuchanAMHillMDCanadian Alteplase for Stroke Effectiveness Study (CASES) InvestigatorsThrombolysis in patients older than 80 years with acute ischaemic stroke: Canadian Alteplase for Stroke Effectiveness StudyJ Neurol Neurosurg Psychiatr200677782682916505004
- MouradianMSSenthilselvanAJicklingGIntravenous rt-PA for acute stroke: comparing its effectiveness in younger and older patientsJ Neurol Neurosurg Psychiatr20057691234123716107357
- García-CaldenteyJAlonso de LeciñanaMSimalPIntravenous thrombolytic treatment in the oldest oldStroke Res Treat2012201292367622848866
- FordGAAhmedNAzevedoEIntravenous alteplase for stroke in those older than 80 years oldStroke201041112568257420930163
- EngelterSTBonatiLHLyrerPAIntravenous thrombolysis in stroke patients of ≥80 versus <80 years of age – a systematic review across cohort studiesAge Ageing200635657258017047006
- SimonJESandlerDLPexmanJHHillMDBuchanAMCalgary Stroke ProgrammeIs intravenous recombinant tissue plasminogen activator (rt-PA) safe for use in patients over 80 years old with acute ischaemic stroke? – The Calgary experienceAge Ageing200433214314914960429
- SungPSChenCHHsiehHCOutcome of acute ischemic stroke in very elderly patients: is intravenous thrombolysis beneficial?Eur Neurol201166211011621849787
- MishraNKAhmedNAndersenGSITS collaboratorsThrombolysis in very elderly people: controlled comparison of SITS International Stroke Thrombolysis Registry and Virtual International Stroke Trials ArchiveBMJ2010341c604621098614
- ChenCIIguchiYGrottaJCIntravenous TPA for very old stroke patientsEur Neurol200554314014416244487
- ZacharatosHHassanAEVazquezGComparison of acute non-thrombolytic and thrombolytic treatments in ischemic stroke patients 80 years or olderAm J Emerg Med201230115816421247724
- LongstrethWTJrKatzRTirschwellDLCushmanMPsatyBMIntravenous tissue plasminogen activator and stroke in the elderlyAm J Emerg Med201028335936320223397
- BoulouisGDumontFCordonnierCBodenantMLeysDHénonHIntravenous thrombolysis for acute cerebral ischaemia in old stroke patients ≥80 years of ageJ Neurol201225971461146722183776
- WilleyJZPetersenNDhamoonMSSafety of thrombolysis in patients over the age of 80Neurologist20121829910122367841
- HenriksenEHLjøstadUTveitenANaessHThomassenLMyglandATPA for ischemic stroke in patients ≥80 yearsActa Neurol Scand2013127530931522988960
- ZeeviNChhabraJSilvermanIELeeNSMcCulloughLDAcute stroke management in the elderlyCerebrovasc Dis200723430430817199089
- BrayBDCampbellJHoffmanATyrrellPJWolfeCDRuddAGStroke thrombolysis in England: an age stratified analysis of practice and outcomeAge Ageing201342224024523174425
- MishraNKDienerHCLydenPDBluhmkiELeesKRVISTA CollaboratorsInfluence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA)Stroke201041122840284821030710
- MartinsSCFriedrichMABrondaniRThrombolytic therapy for acute stroke in the elderly: an emergent condition in developing countriesJ Stroke Cerebrovasc Dis201120545946420813552
- Di CarloALamassaMPracucciGStroke in the very old: clinical presentation and determinants of 3-month functional outcome: A European perspective. European BIOMED Study of Stroke Care GroupStroke199930112313231910548664
- KammersgaardLPJørgensenHSReithJCopenhagen Stroke StudyShort- and long-term prognosis for very old stroke patients. The Copenhagen Stroke StudyAge Ageing200433214915414960430
- FonarowGCReevesMJZhaoXGet With the Guidelines-Stroke Steering Committee and InvestigatorsAge-related differences in characteristics, performance measures, treatment trends, and outcomes in patients with ischemic strokeCirculation2010121787989120142445
- SandercockPWardlawJMLinleyRIIST-3 collaborative groupThe benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trialLancet201237998342352236322632908
- Gómez-ChocoMObachVUrraXThe response to IV rt-PA in very old stroke patientsEur J Neurol200815325325618190509
- KimDFordGAKidwellCSUCLA Intra-Arterial Thrombolysis InvestigatorsIntra-arterial thrombolysis for acute stroke in patients 80 and older: a comparison of results in patients younger than 80 yearsAJNR Am J Neuroradiol200728115916317213448
- ChandraRVLeslie-MazwiTMOhDCElderly patients are at higher risk for poor outcomes after intra-arterial therapyStroke20124392356236122744644
- WilleyJZOrtega-GutierrezSPetersenNImpact of acute ischemic stroke treatment in patients >80 years of age: the specialized program of translational research in acute stroke (SPOTRIAS) consortium experienceStroke20124392369237522798327
- BroderickJPPaleschYYDemchukAMInterventional Management of Stroke (IMS) III InvestigatorsEndovascular therapy after intravenous t-PA versus t-PA alone for strokeN Engl J Med20133681089390323390923
- KidwellCSJahanRGornbeinJMR RESCUE InvestigatorsA trial of imaging selection and endovascular treatment for ischemic strokeN Engl J Med20133681091492323394476
- BerrouschotJRötherJGlahnJKucinskiTFiehlerJThomallaGOutcome and severe hemorrhagic complications of intravenous thrombolysis with tissue plasminogen activator in very old (≥80 years) stroke patientsStroke200536112421242516210554
- MateenFJNasserMSpencerBROutcomes of intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 90 years or olderMayo Clin Proc200984433433819339651
- DerexLAcute stroke management in elderly patientsRev Prat201262912251228 French23272471