Thrombocytopenia and bleeding in myelosuppressed transfusion-dependent patients: a simulation study exploring underlying mechanisms

References

• KreugerALMiddelburgRAZwagingaJJKerkhoffsJLvan der BomJGClinical practice of platelet transfusions in hemato-oncology; a surveyVox Sang2015109919425833739
   PubMed Web of Science ®Google Scholar
• KaufmanRMDjulbegovicBGernsheimerTPlatelet Transfusion: A Clinical Practice Guideline From the AABBAnn Intern Med2014101589
   Web of Science ®Google Scholar
• de VriesRHaasFEnglish translation of the Dutch Blood Transfusion guideline 2011Vox Sang2012103363041022747957
   PubMed Web of Science ®Google Scholar
• YpmaPFKerkhoffsJLvan HiltenJAThe observation of bleeding complications in haemato-oncological patients: stringent watching, relevant reportingTransfus Med2012 ePub103148
   Web of Science ®Google Scholar
• MiddelburgRAYpmaPFvan der MeerPFvan Wordragen-VlaswinkelRJEissenOKerkhoffsJLMeasuring clinical bleeding using a standardized daily report form and a computer algorithm for adjudication of WHO bleeding gradesVox Sang201310514414923517250
   PubMed Web of Science ®Google Scholar
• SlichterSJKaufmanRMAssmannSFDose of prophylactic platelet transfusions and prevention of hemorrhageN Engl J Med201036260061320164484
   PubMed Web of Science ®Google Scholar
• StanworthSJEstcourtLJPowterGA no-prophylaxis platelet-transfusion strategy for hematologic cancersN Engl J Med20133681771178023656642
   PubMed Web of Science ®Google Scholar
• HeddleNMCookRJTinmouthAA randomized controlled trial comparing standard- and low-dose strategies for transfusion of platelets (SToP) to patients with thrombocytopeniaBlood20091131564157319109560
   PubMed Web of Science ®Google Scholar
• KumarAMhaskarRGrossmanBJPlatelet transfusion: a systematic review of the clinical evidenceTransfusion201410
   Google Scholar
• StanworthSJHudsonCLEstcourtLJJohnsonRJWoodEMRisk of bleeding and use of platelet transfusions in patients with hematologic malignancies: recurrent event analysisHaematologica201510074074725795717
   PubMed Web of Science ®Google Scholar
• SlichterSJRelationship between platelet count and bleeding risk in thrombocytopenic patientsTransfus Med Rev20041815316715248165
   PubMed Web of Science ®Google Scholar
• RothmanKJGreenlandSLashTLModern Epidemiology3Wolter Kluwer2009
   Google Scholar
• MiddelburgRAWiersum-OsseltonJCvan de WateringLMvan der BomJGObservational etiologic research: part 1–The etiologic research question: it requires DATATransfusion2013532606260824117626
   PubMed Web of Science ®Google Scholar
• HansonSRSlichterSJPlatelet kinetics in patients with bone marrow hypoplasia: evidence for a fixed platelet requirementBlood198566110511094052629
   PubMed Web of Science ®Google Scholar
• SlichterSJDavisKEnrightHFactors affecting posttransfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patientsBlood20051054106411415692069
   PubMed Web of Science ®Google Scholar
• R: A language and environment for statistical computing [Version 3.2.0Vienna, AustriaR Foundation for Statistical Computing2015
   Google Scholar
• HodESchwartzJPlatelet transfusion refractorinessBr J Haematol200814234836018510692
   PubMed Web of Science ®Google Scholar
• LawrenceJBYomtovianRADillmanCReliability of automated platelet counts: comparison with manual method and utility for prediction of clinical bleedingAm J Hematol1995482442507717373
   PubMed Web of Science ®Google Scholar
• PfuntnerAWierLMStocksCMost Frequent Procedures Performed in U.S. Hospitals, 2011: Statistical Brief #165
   Google Scholar
• Stata Statistical Software [Version 14.1College Station, Texas, USAStataCorp LP2015
   Google Scholar
• RebullaPFinazziGMarangoniFThe threshold for prophylactic platelet transfusions in adults with acute myeloid leukemia. Gruppo Italiano Malattie Ematologiche Maligne dell’AdultoN Engl J Med1997337187018759407153
   PubMed Web of Science ®Google Scholar
• DiedrichBRembergerMShanwellASvahnBMRingdenOA prospective randomized trial of a prophylactic platelet transfusion trigger of 10 × 10(9) per L versus 30 × 10(9) per L in allogeneic hema-topoietic progenitor cell transplant recipientsTransfusion2005451064107215987349
   PubMed Web of Science ®Google Scholar
• HeckmanKDWeinerGJDavisCSStraussRGJonesMPBurnsCPRandomized study of prophylactic platelet transfusion threshold during induction therapy for adult acute leukemia: 10,000/microL versus 20,000/microLJ Clin Oncol199715114311499060557
   PubMed Web of Science ®Google Scholar
• ZumbergMSdel RosarioMLNejameCFA prospective random-ized trial of prophylactic platelet transfusion and bleeding incidence in hematopoietic stem cell transplant recipients: 10,000/L versus 20,000/microL triggerBiol Blood Marrow Transplant2002856957612434952
   PubMed Web of Science ®Google Scholar
• Mirasol Clinical Evaluation Study GroupA randomized controlled clinical trial evaluating the performance and safety of platelets treated with MIRASOL pathogen reduction technologyTransfusion2010502362237520492615
   PubMed Web of Science ®Google Scholar
• DjulbegovicBClarkeMScientific and ethical issues in equivalence trialsJAMA20012851206120811231752
   PubMed Web of Science ®Google Scholar
• PiaggioGElbourneDRPocockSJEvansSJAltmanDGReporting of noninferiority and equivalence randomized trials: extension of the CONSORT 2010 statementJAMA20123082594260423268518
   PubMed Web of Science ®Google Scholar
• MiettinenOSKarpIEpidemiological Research: An IntroductionDordrechtSpringer2012
   Google Scholar
• HernanMAA definition of causal effect for epidemiological researchJ Epidemiol Community Health20045826527115026432
   PubMed Web of Science ®Google Scholar
• HeddleNMThe research questionTransfusion200747151717207225
   PubMed Web of Science ®Google Scholar
• EckhardtCLvan VelzenASFijnvandraatCJvan der BomJGDissecting intensive treatment as risk factor for inhibitor development in haemophiliaHaemophilia201622e241e24427076357
   PubMed Web of Science ®Google Scholar
• StukelTAFisherESWennbergDEAlterDAGottliebDJVermeu-lenMJAnalysis of observational studies in the presence of treatment selection bias: effects of invasive cardiac management on AMI survival using propensity score and instrumental variable methodsJAMA200729727828517227979
   PubMed Web of Science ®Google Scholar
• BorJMoscoeEMutevedziPNewellMLBarnighausenTRegression discontinuity designs in epidemiology: causal inference without randomized trialsEpidemiology20142572973725061922
   PubMed Web of Science ®Google Scholar
• BoefAGvanPJArbousMSPhysician’s preference-based instrumental variable analysis: is it valid and useful in a moderate-sized study?Epidemiology20142592392725051311
   PubMed Web of Science ®Google Scholar
• GuoSLiXDuXLiuHXieGGroup-Based Trajectory Analysis for Long-Term Use of Warfarin Therapy in Atrial Fibrillation PatientsStud Health Technol Inform20172451024102829295256
   PubMedGoogle Scholar